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NO20161485A1 - Kationiske bakterieklorofyllderivater og anvendelser derav - Google Patents

Kationiske bakterieklorofyllderivater og anvendelser derav

Info

Publication number
NO20161485A1
NO20161485A1 NO20161485A NO20161485A NO20161485A1 NO 20161485 A1 NO20161485 A1 NO 20161485A1 NO 20161485 A NO20161485 A NO 20161485A NO 20161485 A NO20161485 A NO 20161485A NO 20161485 A1 NO20161485 A1 NO 20161485A1
Authority
NO
Norway
Prior art keywords
cationic
chlorophyll derivatives
bacterial chlorophyll
bacterial
derivatives
Prior art date
Application number
NO20161485A
Other languages
English (en)
Inventor
Avraham Cohen
Avigdor Scherz
Yoram Salomon
Alexander Brandis
Doron Eren
Original Assignee
Yeda Res And Development Company Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20161485A1 publication Critical patent/NO20161485A1/no
Application filed by Yeda Res And Development Company Ltd filed Critical Yeda Res And Development Company Ltd

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D229/00—Heterocyclic compounds containing rings of less than five members having two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20161485A 2004-06-07 2016-09-19 Kationiske bakterieklorofyllderivater og anvendelser derav NO20161485A1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57719604P 2004-06-07 2004-06-07
PCT/IL2005/000602 WO2005120573A2 (en) 2004-06-07 2005-06-07 Cationic bacteriochlorophyll derivatives and uses thereof

Publications (1)

Publication Number Publication Date
NO20161485A1 true NO20161485A1 (no) 2007-03-06

Family

ID=35044538

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20070083A NO339304B1 (no) 2004-06-07 2007-01-05 Kationiske bakterieklorofyllderivater, farmasøytiske sammensetninger inneholdende slike, og anvendelse derav.
NO20161485A NO20161485A1 (no) 2004-06-07 2016-09-19 Kationiske bakterieklorofyllderivater og anvendelser derav

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20070083A NO339304B1 (no) 2004-06-07 2007-01-05 Kationiske bakterieklorofyllderivater, farmasøytiske sammensetninger inneholdende slike, og anvendelse derav.

Country Status (19)

Country Link
US (1) US8207154B2 (no)
EP (2) EP2322173B1 (no)
JP (1) JP5372371B2 (no)
KR (1) KR101191700B1 (no)
CN (1) CN1980661B (no)
AU (1) AU2005251556B2 (no)
BR (1) BRPI0511909A (no)
CA (1) CA2569675C (no)
CY (2) CY1118194T1 (no)
DK (2) DK1753457T3 (no)
ES (2) ES2602204T3 (no)
HU (2) HUE030586T2 (no)
MX (1) MXPA06014326A (no)
NO (2) NO339304B1 (no)
NZ (1) NZ551845A (no)
PT (2) PT2322173T (no)
RU (1) RU2397172C2 (no)
WO (1) WO2005120573A2 (no)
ZA (1) ZA200700169B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2008665A1 (fr) * 2007-06-25 2008-12-31 Steba Biotech N.V. Formulation injectable pour thérapie photodynamique
ES2764781T3 (es) 2008-02-27 2020-06-04 Yeda Res And Development Company Ltd Conjugados de RGD-(bacterio)clorofila para uso en el diagnóstico de tumores que comprenden dominios necróticos
JP6215203B2 (ja) 2011-08-23 2017-10-18 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ． Ｌｔｄ 眼疾患および障害の治療用の（バクテリオ）クロロフィル光増感剤
AU2014229637B2 (en) 2013-03-11 2017-05-04 Tookad Ip Sarl Method for producing bacteriochlorophyll a
RU2548675C9 (ru) * 2013-05-29 2015-11-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет тонких химических технологий имени М.В. Ломоносова" (МИТХТ им. М.В. Ломоносова) Аминоамиды в ряду бактериохлорофилла a, обладающие фотодинамической активностью, и способ их получения
JP6218073B2 (ja) * 2013-11-26 2017-10-25 国立大学法人群馬大学 細胞・組織内酸素濃度測定のための高感度近赤外りん光イリジウム錯体
RU2549953C2 (ru) * 2013-12-25 2015-05-10 Федеральное государственное унитарное предприятие Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Фотосенсибилизатор для фотодинамической терапии
RU2610566C1 (ru) * 2015-09-17 2017-02-13 Сергей Сергеевич Брусов Способ фотодинамической терапии локальных очагов инфекции
CN105424857A (zh) * 2015-12-01 2016-03-23 浙江汇能生物股份有限公司 一种二甲基半胱胺盐酸盐的高效液相色谱分析方法
US10836774B2 (en) 2016-11-30 2020-11-17 North Carolina State University Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds
CN113677685B (zh) * 2019-01-25 2025-03-04 桑科能源股份有限公司 光敏剂化合物、制备方法和在植物中的应用
US20250269031A1 (en) * 2020-11-24 2025-08-28 The Regents Of The University Of California Mitochondria targeting quinolinium-drug conjugates and their self-assembling nanoformulations for cancer therapy
CN115093422B (zh) * 2022-06-15 2023-06-20 西北工业大学 一种基于代谢标记策略的新型光敏剂及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997019081A1 (en) * 1995-11-24 1997-05-29 Yeda Research And Development Co. Ltd. Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
WO2000033833A1 (en) * 1998-12-09 2000-06-15 Yeda Research And Development Co. Ltd. Palladium-substituted bacteriochlorophyll derivatives and use thereof
WO2001040232A1 (en) * 1999-12-01 2001-06-07 Yeda Research And Development Co. Ltd. Chlorophyll and bacteriochlorophyll esters, and their preparation

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US3050296A (en) * 1960-12-19 1962-08-21 Trimborn Hans Transport roller for industrial furnaces
US3203888A (en) * 1961-04-24 1965-08-31 Exxon Research Engineering Co Treating athabaska sands utilizing a flotation gas
DE2018970A1 (de) 1970-04-21 1971-11-11 Badische Anilin- & Soda Fabrik AG, 6700 Ludwigshafen Verfahren zur Herstellung von beta-Aminoäthylsulfoniumverbindungen
US5330741A (en) * 1992-02-24 1994-07-19 The Regents Of The University Of California Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors
US5744598A (en) 1992-06-19 1998-04-28 University Of Toledo Imines of porphyrins, of porphyrin derivatives, and of related compounds, and pharmaceutical compositions containing such imines
IL102645A (en) 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
US6147195A (en) 1993-07-26 2000-11-14 Yeda Research And Development Co., Ltd. Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
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CA2449031C (en) * 2001-06-01 2010-07-27 Ceramoptec Industries, Inc. Water-soluble porphyrin derivatives for photodynamic therapy, their use and manufacture
US20030203888A1 (en) * 2001-06-06 2003-10-30 Boyle Ross William Chromophores
US20040266748A1 (en) 2001-10-03 2004-12-30 Robinson Byron C Photosensitizing carbamate derivatives
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DE10154436A1 (de) 2001-11-07 2003-05-15 Rodotech Gmbh pyro-Bakteriopheophorbidderivate
GB0130778D0 (en) * 2001-12-21 2002-02-06 Catalyst Biomedica Ltd Novel compounds
CA2485224A1 (en) 2002-05-08 2003-11-20 Yeda Research And Development Co. Ltd. Sensitized online bold-mri imaging method
EP1517684B1 (en) * 2002-06-27 2009-07-22 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
RU2223274C1 (ru) * 2002-09-04 2004-02-10 ООО "Фотогем" ГИДРАЗИДЫ В РЯДУ БАКТЕРИОХЛОРОФИЛЛА a, ОБЛАДАЮЩИЕ ФОТОДИНАМИЧЕСКОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ
IL152900A0 (en) 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997019081A1 (en) * 1995-11-24 1997-05-29 Yeda Research And Development Co. Ltd. Synthetic metal-substituted bacteriochlorophyll derivatives and use thereof
WO2000033833A1 (en) * 1998-12-09 2000-06-15 Yeda Research And Development Co. Ltd. Palladium-substituted bacteriochlorophyll derivatives and use thereof
WO2001040232A1 (en) * 1999-12-01 2001-06-07 Yeda Research And Development Co. Ltd. Chlorophyll and bacteriochlorophyll esters, and their preparation

Also Published As

Publication number Publication date
NO20070083L (no) 2007-03-06
CA2569675C (en) 2015-03-17
AU2005251556A1 (en) 2005-12-22
AU2005251556B2 (en) 2011-04-14
BRPI0511909A (pt) 2008-01-15
HUE030586T2 (en) 2017-06-28
CN1980661B (zh) 2011-09-28
KR20070026563A (ko) 2007-03-08
CA2569675A1 (en) 2005-12-22
CY1118203T1 (el) 2017-06-28
ZA200700169B (en) 2008-05-28
EP2322173A1 (en) 2011-05-18
PT2322173T (pt) 2016-11-14
WO2005120573A3 (en) 2006-01-26
KR101191700B1 (ko) 2012-10-16
ES2602204T3 (es) 2017-02-20
HUE031075T2 (en) 2017-06-28
WO2005120573A2 (en) 2005-12-22
CY1118194T1 (el) 2017-06-28
DK1753457T3 (en) 2016-12-05
JP5372371B2 (ja) 2013-12-18
PT1753457T (pt) 2016-11-10
CN1980661A (zh) 2007-06-13
US8207154B2 (en) 2012-06-26
JP2008501780A (ja) 2008-01-24
EP1753457A2 (en) 2007-02-21
NO339304B1 (no) 2016-11-21
EP1753457B8 (en) 2016-09-21
DK2322173T3 (en) 2016-12-05
RU2006146677A (ru) 2008-07-20
EP1753457B1 (en) 2016-08-10
US20080076748A1 (en) 2008-03-27
EP2322173B1 (en) 2016-08-10
NZ551845A (en) 2010-08-27
RU2397172C2 (ru) 2010-08-20
MXPA06014326A (es) 2007-02-19
ES2602460T3 (es) 2017-02-21

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