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NO20092138L - Forbindelser og sammensetninger som proteinkinase inhibitorer - Google Patents

Forbindelser og sammensetninger som proteinkinase inhibitorer

Info

Publication number
NO20092138L
NO20092138L NO20092138A NO20092138A NO20092138L NO 20092138 L NO20092138 L NO 20092138L NO 20092138 A NO20092138 A NO 20092138A NO 20092138 A NO20092138 A NO 20092138A NO 20092138 L NO20092138 L NO 20092138L
Authority
NO
Norway
Prior art keywords
compounds
compositions
protein kinase
kinase inhibitors
diseases
Prior art date
Application number
NO20092138A
Other languages
English (en)
Inventor
Werner Breitenstein
Paul William Manley
Lawrence Blas Perez
Wojciech Wrona
Valentina Molteni
Xiaolin Li
Donatella Chianelli
Jon Loren
Juliet Nabakka
Xiaodong Liu
Laszlo Revesz
Clinton Brooks
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of NO20092138L publication Critical patent/NO20092138L/no

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Medicinal Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer en ny klasse av forbindelser, farmasøytiske sammensetninger som innbefatter slike forbindelser og fremgangsmåter for anvendelse av slike forbindelser for behandling eller hindring av sykdommer eller forstyrrelser assosiert med abnormal eller deregulert kinaseaktivitet, særlig sykdommer eller forstyrrelser som involverer abnormal aktivering av c-kit, PDGFRa og PDGFRß kinaser.
NO20092138A 2006-11-03 2009-06-02 Forbindelser og sammensetninger som proteinkinase inhibitorer NO20092138L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86437806P 2006-11-03 2006-11-03
PCT/US2007/083543 WO2008058037A1 (en) 2006-11-03 2007-11-02 Compounds and compositions as protein kinase inhibitors

Publications (1)

Publication Number Publication Date
NO20092138L true NO20092138L (no) 2009-07-13

Family

ID=39119736

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092138A NO20092138L (no) 2006-11-03 2009-06-02 Forbindelser og sammensetninger som proteinkinase inhibitorer

Country Status (20)

Country Link
US (1) US20100048539A1 (no)
EP (1) EP2079729A1 (no)
JP (1) JP2010509349A (no)
KR (2) KR20120049397A (no)
CN (1) CN101622244A (no)
AU (1) AU2007317349B2 (no)
BR (1) BRPI0718677A2 (no)
CA (1) CA2668190A1 (no)
CO (1) CO6241115A2 (no)
CR (1) CR10755A (no)
EA (1) EA200970447A1 (no)
EC (1) ECSP099378A (no)
IL (1) IL198315A0 (no)
MA (1) MA30906B1 (no)
MX (1) MX2009004716A (no)
NO (1) NO20092138L (no)
RU (1) RU2009120882A (no)
SM (1) SMAP200900031A (no)
TN (1) TN2009000163A1 (no)
WO (1) WO2008058037A1 (no)

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LT2799427T (lt) 2006-07-05 2018-11-26 Fibrotech Therapeutics Pty Ltd Terapiniai junginiai
EA019524B1 (ru) * 2007-05-04 2014-04-30 Айрм Ллк СОЕДИНЕНИЯ И КОМПОЗИЦИИ КАК ИНГИБИТОРЫ КИНАЗЫ с-kit И PDGFR
EP2152079A4 (en) * 2007-06-04 2011-03-09 Avila Therapeutics Inc HETEROCYCLIC COMPOUNDS AND USES THEREOF
JP5303557B2 (ja) 2007-08-22 2013-10-02 アイアールエム・リミテッド・ライアビリティ・カンパニー キナーゼ阻害剤である２−ヘテロアリールアミノ−ピリミジン誘導体
WO2009026276A1 (en) 2007-08-22 2009-02-26 Irm Llc 5- (4- (haloalkoxy) phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors
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UA103918C2 (en) 2009-03-02 2013-12-10 Айерем Элелси N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
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EP2576532B1 (en) 2010-06-07 2018-07-18 Novomedix, LLC Furanyl compounds and the use thereof
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UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
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