NO20091099L - Zabicykloforbindelser som inhibitorer av monoamingjenopptakelse - Google Patents

Zabicykloforbindelser som inhibitorer av monoamingjenopptakelse

Info

Publication number: NO20091099L
Authority: NO; Norway
Prior art keywords: group; zabicyclo; inhibitors; compounds; monoamine reuptake
Prior art date: 2006-09-11

Application number

NO20091099A

Other languages

English (en)

Norwegian (no)

Inventor

Romano Di Fabio

Silvia Terreni

Fabrizio Micheli

Barbara Bertani

Giovanni Tedesco

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-11

Filing date

2009-03-13

Publication date

2009-04-03

2006-09-11 Priority claimed from GB0617863A external-priority patent/GB0617863D0/en

2006-09-11 Priority claimed from GB0617868A external-priority patent/GB0617868D0/en

2007-08-22 Priority claimed from GB0716371A external-priority patent/GB0716371D0/en

2009-03-13 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2009-04-03 Publication of NO20091099L publication Critical patent/NO20091099L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Addiction (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Virology (AREA)
Diabetes (AREA)
Psychology (AREA)
Obesity (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Oncology (AREA)
Hospice & Palliative Care (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Molecular Biology (AREA)
Pregnancy & Childbirth (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Emergency Medicine (AREA)

NO20091099A 2006-09-11 2009-03-13 Zabicykloforbindelser som inhibitorer av monoamingjenopptakelse NO20091099L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0617863A GB0617863D0 (en)	2006-09-11	2006-09-11	Chemical compounds
GB0617868A GB0617868D0 (en)	2006-09-11	2006-09-11	Chemical compounds
GB0716371A GB0716371D0 (en)	2007-08-22	2007-08-22	Chemical compounds
PCT/EP2007/059381 WO2008031772A1 (en)	2006-09-11	2007-09-07	Azabicyclic compounds as inhibitors of monoamines reuptake

Publications (1)

Publication Number	Publication Date
NO20091099L true NO20091099L (no)	2009-04-03

Family

ID=38561834

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20091099A NO20091099L (no)	2006-09-11	2009-03-13	Zabicykloforbindelser som inhibitorer av monoamingjenopptakelse

Country Status (19)

Country	Link
US (2)	US7691893B2 (es)
EP (1)	EP2064186A1 (es)
JP (1)	JP4448198B2 (es)
KR (1)	KR20090064447A (es)
AR (1)	AR062737A1 (es)
AU (1)	AU2007296301A1 (es)
BR (1)	BRPI0716532A2 (es)
CA (1)	CA2662538A1 (es)
CL (1)	CL2007002619A1 (es)
CO (1)	CO6150149A2 (es)
CR (1)	CR10671A (es)
EA (1)	EA200970266A1 (es)
IL (1)	IL197297A0 (es)
MA (1)	MA30767B1 (es)
MX (1)	MX2009002625A (es)
NO (1)	NO20091099L (es)
PE (1)	PE20081368A1 (es)
TW (1)	TW200826934A (es)
WO (1)	WO2008031772A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2064186A1 (en)	2006-09-11	2009-06-03	Glaxo Group Limited	Azabicyclic compounds as inhibitors of monoamines reuptake
GB0716573D0 (en) *	2007-08-24	2007-10-03	Glaxo Group Ltd	Chemical compounds
GB0804326D0 (en) *	2008-03-07	2008-04-16	Glaxo Group Ltd	Novel compounds
WO2010125033A1 (en) *	2009-04-29	2010-11-04	Glaxo Group Limited	Azabicyclo[4.1.0]heptane derivatives
WO2010130672A1 (en) *	2009-05-12	2010-11-18	Glaxo Group Limited	Azabicyclo [4.1.0] heptane derivatives and their use as monoamine reuptake inhibitors
WO2010133569A1 (en) *	2009-05-20	2010-11-25	Glaxo Group Limited	Azabicyclo[4.1.0]heptane derivatives
WO2010146025A1 (en) *	2009-06-17	2010-12-23	Glaxo Group Limited	Tricyclic azabicyclo [4.1.0] heptane derivatives as inhibitors of serotonin, dopamine and norepinephrine re-uptake
US8268848B2 (en)	2010-09-22	2012-09-18	Eisai R&D Management Co., Ltd.	Cyclopropane compound
DE102011100831A1 (de)	2011-05-07	2012-11-08	Studiengesellschaft Kohle Mbh	Verfahren zur Herstellung von GSK 1360707 und verwandter Verbindungen mit 6-Aryl-1-[(alkyloxy) alkyl]-3-azabicyclo[4.1.0]heptan Grundgerüst
AU2015336463B2 (en)	2014-10-23	2020-06-18	Eisai R&D Management Co., Ltd.	Compositions and methods for treating insomnia
US12059408B2 (en)	2020-08-13	2024-08-13	Boehringer Ingelheim International Gmbh	Treatment of cognitive impairment associated with schizophrenia
WO2022078927A1 (en)	2020-10-13	2022-04-21	Boehringer Ingelheim International Gmbh	Process of reworking

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2008A (en) *		1841-03-18		Gas-lamp eok conducting gas pkom ah elevated buhner to one below it
US2004A (en) *		1841-03-12		Improvement in the manner of constructing and propelling steam-vessels
US4131611A (en) *	1975-07-31	1978-12-26	American Cyanamid Company	Azabicyclohexanes
US4435419A (en) *	1981-07-01	1984-03-06	American Cyanamid Company	Method of treating depression using azabicyclohexanes
AU672644B2 (en) *	1992-12-23	1996-10-10	Neurosearch A/S	Aryl substituted heterocyclic compounds
DE69705608T2 (de)	1996-02-22	2002-05-16	Neurosearch A/S, Ballerup	Tropanderivate, deren herstellung und verwendung
ES2329739T3 (es) *	1997-04-07	2009-11-30	Georgetown University	Analogos de cocaina.
US6303627B1 (en) *	1998-06-19	2001-10-16	Eli Lilly And Company	Inhibitors of serotonin reuptake
US6372919B1 (en)	2001-01-11	2002-04-16	Dov Pharmaceutical, Inc.	(+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent
US6569887B2 (en) *	2001-08-24	2003-05-27	Dov Pharmaceuticals Inc.	(−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US20060173064A1 (en)	2001-08-24	2006-08-03	Lippa Arnold S	(-)-1-(3,4-Dichlorophenyl)-3-azabi cyclo[3.1.0]hexane, compositions thereof, and uses for treating alcohol-related disorders
DE10306250A1 (de)	2003-02-14	2004-09-09	Aventis Pharma Deutschland Gmbh	Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7223788B2 (en)	2003-02-14	2007-05-29	Sanofi-Aventis Deutschland Gmbh	Substituted N-aryl heterocycles, process for their preparation and their use as medicaments
EP1735302B1 (en) *	2004-02-27	2010-06-16	Eli Lilly And Company	4-amino-piperidine derivatives as monoamine uptake inhibitors
EP2064186A1 (en)	2006-09-11	2009-06-03	Glaxo Group Limited	Azabicyclic compounds as inhibitors of monoamines reuptake

2007
- 2007-09-07 EP EP07803326A patent/EP2064186A1/en not_active Withdrawn
- 2007-09-07 EA EA200970266A patent/EA200970266A1/ru unknown
- 2007-09-07 KR KR1020097007365A patent/KR20090064447A/ko not_active Withdrawn
- 2007-09-07 AU AU2007296301A patent/AU2007296301A1/en not_active Abandoned
- 2007-09-07 US US11/851,459 patent/US7691893B2/en not_active Expired - Fee Related
- 2007-09-07 PE PE2007001202A patent/PE20081368A1/es not_active Application Discontinuation
- 2007-09-07 US US12/440,852 patent/US20100035914A1/en not_active Abandoned
- 2007-09-07 MX MX2009002625A patent/MX2009002625A/es unknown
- 2007-09-07 CA CA002662538A patent/CA2662538A1/en not_active Abandoned
- 2007-09-07 JP JP2009527793A patent/JP4448198B2/ja not_active Expired - Fee Related
- 2007-09-07 WO PCT/EP2007/059381 patent/WO2008031772A1/en not_active Ceased
- 2007-09-07 BR BRPI0716532-3A2A patent/BRPI0716532A2/pt not_active IP Right Cessation
- 2007-09-10 TW TW096133638A patent/TW200826934A/zh unknown
- 2007-09-10 CL CL200702619A patent/CL2007002619A1/es unknown
- 2007-09-11 AR ARP070104006A patent/AR062737A1/es not_active Application Discontinuation
2009
- 2009-02-26 IL IL197297A patent/IL197297A0/en unknown
- 2009-03-10 CO CO09024346A patent/CO6150149A2/es unknown
- 2009-03-13 NO NO20091099A patent/NO20091099L/no not_active Application Discontinuation
- 2009-03-19 CR CR10671A patent/CR10671A/es not_active Application Discontinuation
- 2009-03-30 MA MA31737A patent/MA30767B1/fr unknown

Also Published As

Publication number	Publication date
JP2010502761A (ja)	2010-01-28
CA2662538A1 (en)	2008-03-20
JP4448198B2 (ja)	2010-04-07
EP2064186A1 (en)	2009-06-03
US7691893B2 (en)	2010-04-06
MX2009002625A (es)	2009-03-24
MA30767B1 (fr)	2009-10-01
CR10671A (es)	2009-04-29
WO2008031772A1 (en)	2008-03-20
US20100035914A1 (en)	2010-02-11
AU2007296301A1 (en)	2008-03-20
PE20081368A1 (es)	2008-11-19
BRPI0716532A2 (pt)	2013-09-24
AR062737A1 (es)	2008-11-26
TW200826934A (en)	2008-07-01
EA200970266A1 (ru)	2009-08-28
US20080114049A1 (en)	2008-05-15
CO6150149A2 (es)	2010-04-20
KR20090064447A (ko)	2009-06-18
CL2007002619A1 (es)	2008-04-18
IL197297A0 (en)	2009-12-24

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EA200970472A1 (ru)	2009-10-30	Замещенные пиразолы, композиции, их содержащие, способ получения и применение
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Legal Events

Date	Code	Title	Description
2012-04-30	FC2A	Withdrawal, rejection or dismissal of laid open patent application