NO20075829L - Syntese - Google Patents
SynteseInfo
- Publication number
- NO20075829L NO20075829L NO20075829A NO20075829A NO20075829L NO 20075829 L NO20075829 L NO 20075829L NO 20075829 A NO20075829 A NO 20075829A NO 20075829 A NO20075829 A NO 20075829A NO 20075829 L NO20075829 L NO 20075829L
- Authority
- NO
- Norway
- Prior art keywords
- do3a
- butyl ester
- tri
- salt
- synthesis
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HHLZCENAOIROSL-UHFFFAOYSA-N 2-[4,7-bis(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid Chemical compound OC(=O)CN1CCNCCN(CC(O)=O)CCN(CC(O)=O)CC1 HHLZCENAOIROSL-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- NMHVTLJFPDOJOD-UHFFFAOYSA-N tert-butyl 2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetate Chemical compound CC(C)(C)OC(=O)CN1CCNCCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 NMHVTLJFPDOJOD-UHFFFAOYSA-N 0.000 abstract 1
- 238000010626 work up procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Oppfinnelsen dreier seg om en forbedret prosess for å framstille beskyttet D03A, for eksempel D03A-tri-t- butylester (l,4,7,10-tetiaazasyklododekan-l,4,7-trieddiksyre-tri-t-butylester). Forbindelsen fiiamstilles i form av et salt. Prosessen inneholder en opparbeidingsprosedyre som gir D03A-tri-t-butylester i form av et salt med særs høy renhet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20075829A NO20075829L (no) | 2005-04-19 | 2007-11-13 | Syntese |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20051911A NO20051911D0 (no) | 2005-04-19 | 2005-04-19 | Synthesis |
| PCT/NO2006/000141 WO2006112723A1 (en) | 2005-04-19 | 2006-04-18 | Synthesis of cyclen derivatives |
| NO20075829A NO20075829L (no) | 2005-04-19 | 2007-11-13 | Syntese |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20075829L true NO20075829L (no) | 2007-11-13 |
Family
ID=35267069
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20051911A NO20051911D0 (no) | 2005-04-19 | 2005-04-19 | Synthesis |
| NO20075829A NO20075829L (no) | 2005-04-19 | 2007-11-13 | Syntese |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20051911A NO20051911D0 (no) | 2005-04-19 | 2005-04-19 | Synthesis |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8138332B2 (no) |
| EP (1) | EP1877389B1 (no) |
| JP (1) | JP2008538371A (no) |
| KR (1) | KR20080003816A (no) |
| CN (1) | CN101160292B (no) |
| AT (1) | ATE545636T1 (no) |
| AU (1) | AU2006237745B2 (no) |
| BR (1) | BRPI0610730A2 (no) |
| CA (1) | CA2604219A1 (no) |
| ES (1) | ES2379004T3 (no) |
| MX (1) | MX2007013113A (no) |
| NO (2) | NO20051911D0 (no) |
| RU (1) | RU2405776C2 (no) |
| WO (1) | WO2006112723A1 (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009266944A (ja) | 2008-04-23 | 2009-11-12 | Toshiba Corp | 三次元積層不揮発性半導体メモリ |
| KR101253100B1 (ko) * | 2010-02-16 | 2013-04-10 | 경북대학교 산학협력단 | 폴리아자마크로사이클릭 화합물, 그 제조 방법 및 생의학적 적용 |
| US10994016B2 (en) | 2015-09-15 | 2021-05-04 | Northwestern University | Graphene oxide mediated cellular delivery of gadolinium-labeled molecules |
| KR102703312B1 (ko) * | 2015-12-10 | 2024-09-05 | 브라코 이미징 에스.피.에이. | 조영제 |
| GB201522412D0 (en) * | 2015-12-18 | 2016-02-03 | Ge Healthcare As | Dota synthesis |
| CN110835326B (zh) * | 2018-08-15 | 2023-04-14 | 正大天晴药业集团股份有限公司 | 大环螯合剂及其中间体的制备方法 |
| WO2021116165A1 (en) * | 2019-12-13 | 2021-06-17 | Bracco Imaging Spa | Manufacturing of protected do3a |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9320277D0 (en) * | 1993-10-01 | 1993-11-17 | Nycomed Salutar Inc | Chelants |
| GB9115375D0 (en) * | 1991-07-17 | 1991-09-04 | Salutar Inc | Compounds |
| JP5335171B2 (ja) * | 2000-09-29 | 2013-11-06 | アノーメッド インコーポレイティド | N−1保護したn環窒素含有環式ポリアミンの調製のためのプロセスおよびその生成物 |
| US20050033106A1 (en) * | 2003-07-08 | 2005-02-10 | Wing Tak Wong | Synthesis of tris N-alkylated 1,4,7,10-tetraazacyclododecanes |
-
2005
- 2005-04-19 NO NO20051911A patent/NO20051911D0/no unknown
-
2006
- 2006-04-18 EP EP06733113A patent/EP1877389B1/en not_active Not-in-force
- 2006-04-18 KR KR1020077023901A patent/KR20080003816A/ko not_active Abandoned
- 2006-04-18 US US11/911,848 patent/US8138332B2/en not_active Expired - Fee Related
- 2006-04-18 ES ES06733113T patent/ES2379004T3/es active Active
- 2006-04-18 AT AT06733113T patent/ATE545636T1/de active
- 2006-04-18 WO PCT/NO2006/000141 patent/WO2006112723A1/en not_active Ceased
- 2006-04-18 RU RU2007137806/04A patent/RU2405776C2/ru not_active IP Right Cessation
- 2006-04-18 CN CN2006800127928A patent/CN101160292B/zh not_active Expired - Fee Related
- 2006-04-18 BR BRPI0610730-3A patent/BRPI0610730A2/pt not_active IP Right Cessation
- 2006-04-18 AU AU2006237745A patent/AU2006237745B2/en not_active Ceased
- 2006-04-18 MX MX2007013113A patent/MX2007013113A/es active IP Right Grant
- 2006-04-18 CA CA002604219A patent/CA2604219A1/en not_active Abandoned
- 2006-04-18 JP JP2008507582A patent/JP2008538371A/ja not_active Ceased
-
2007
- 2007-11-13 NO NO20075829A patent/NO20075829L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006237745A1 (en) | 2006-10-26 |
| KR20080003816A (ko) | 2008-01-08 |
| CN101160292B (zh) | 2010-11-03 |
| CN101160292A (zh) | 2008-04-09 |
| JP2008538371A (ja) | 2008-10-23 |
| RU2405776C2 (ru) | 2010-12-10 |
| AU2006237745B2 (en) | 2012-02-23 |
| CA2604219A1 (en) | 2006-10-26 |
| ATE545636T1 (de) | 2012-03-15 |
| MX2007013113A (es) | 2008-01-11 |
| NO20051911D0 (no) | 2005-04-19 |
| ES2379004T3 (es) | 2012-04-19 |
| WO2006112723A1 (en) | 2006-10-26 |
| RU2007137806A (ru) | 2009-05-27 |
| US8138332B2 (en) | 2012-03-20 |
| EP1877389A1 (en) | 2008-01-16 |
| EP1877389B1 (en) | 2012-02-15 |
| US20090216011A1 (en) | 2009-08-27 |
| BRPI0610730A2 (pt) | 2012-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CREP | Change of representative |
Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA |
|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |