NO20073797L - Humane monoklonale antistoffer mot prostata spesifikt membran antigen (PSMA) - Google Patents
Humane monoklonale antistoffer mot prostata spesifikt membran antigen (PSMA)Info
- Publication number
- NO20073797L NO20073797L NO20073797A NO20073797A NO20073797L NO 20073797 L NO20073797 L NO 20073797L NO 20073797 A NO20073797 A NO 20073797A NO 20073797 A NO20073797 A NO 20073797A NO 20073797 L NO20073797 L NO 20073797L
- Authority
- NO
- Norway
- Prior art keywords
- monoclonal antibodies
- psma
- human monoclonal
- antibodies
- antibodies against
- Prior art date
Links
- 102100041003 Glutamate carboxypeptidase 2 Human genes 0.000 title abstract 3
- 101000892862 Homo sapiens Glutamate carboxypeptidase 2 Proteins 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 229940127121 immunoconjugate Drugs 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001481 poly(stearyl methacrylate) Polymers 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SAMMENDRAG Foreliggende oppfinnelse tilveiebringer isolerte monoklonale antistoffer, spesielt humane monoklonale antistoffer, som spesifikt binder til PSMA med høy affinitet. Nukleinsyremolekyler som koder for antistoffene ifølge oppfinnelsen, ekspresjonsvektorer, vertsceller og fremgangsmåter for å uttrykke antistoffene ifølge oppfinnelsen tilveiebringes også. Immunokonjugater, bispesifikke molekyler og farmasøytiske blandinger omfattende antistoffene ifølge oppfinnelsen er også gitt. Oppfinnelsen tilveiebringer også fremgangsmåter for behandling av kreft.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65412505P | 2005-02-18 | 2005-02-18 | |
| US72049905P | 2005-09-26 | 2005-09-26 | |
| US74841705P | 2005-12-08 | 2005-12-08 | |
| PCT/US2006/005852 WO2006089230A2 (en) | 2005-02-18 | 2006-02-17 | Human monoclonal antibodies to prostate specific membrane antigen (psma) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20073797L true NO20073797L (no) | 2007-09-12 |
Family
ID=36658707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20073797A NO20073797L (no) | 2005-02-18 | 2007-07-20 | Humane monoklonale antistoffer mot prostata spesifikt membran antigen (PSMA) |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20090297438A1 (no) |
| EP (1) | EP1851250B1 (no) |
| JP (1) | JP2008529556A (no) |
| KR (1) | KR20070115967A (no) |
| CN (1) | CN101124249B (no) |
| AU (1) | AU2006214031A1 (no) |
| BR (1) | BRPI0607757A2 (no) |
| CA (1) | CA2598522A1 (no) |
| CY (1) | CY1113089T1 (no) |
| DK (1) | DK1851250T3 (no) |
| ES (1) | ES2386366T3 (no) |
| HR (1) | HRP20120709T1 (no) |
| IL (1) | IL184733A (no) |
| MX (1) | MX2007009878A (no) |
| NO (1) | NO20073797L (no) |
| NZ (1) | NZ556661A (no) |
| PL (1) | PL1851250T3 (no) |
| PT (1) | PT1851250E (no) |
| WO (1) | WO2006089230A2 (no) |
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| EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
| DE102008010363A1 (de) * | 2008-02-18 | 2009-08-20 | Lang, Florian, Prof. Dr.med. | Sgk1 als therapeutisches und diagnostisches Target für karzinomatöse Erkrankungen |
| US20110189093A1 (en) * | 2008-04-14 | 2011-08-04 | Proscan Rx Pharma | Prostate specific membrane antigen antibodies and antigen binding fragments |
| WO2010027513A2 (en) | 2008-09-08 | 2010-03-11 | Psma Development Company, Llc | Methods for killing psma-expressing, taxane-resistant cancer cells |
| PL2352763T5 (pl) | 2008-10-01 | 2023-01-30 | Amgen Research (Munich) Gmbh | Bispecyficzne przeciwciała jednołańcuchowe o specyficzności wobec antygenów docelowych o dużej masie cząsteczkowej |
| DK2356153T3 (en) | 2008-10-01 | 2016-07-04 | Amgen Res Munich Gmbh | Bispecific single CHAIN PSMAXCD3 ANTIBODY THAT ARE SPECIFICALLY TO ALL SPECIES |
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| TWI629357B (zh) * | 2009-10-02 | 2018-07-11 | 安進研究(慕尼黑)有限責任公司 | 跨物種特異性的PSMAxCD3雙特異性單鏈抗體 |
| TWI653333B (zh) | 2010-04-01 | 2019-03-11 | 安進研究(慕尼黑)有限責任公司 | 跨物種專一性之PSMAxCD3雙專一性單鏈抗體 |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| BR112013027224A8 (pt) | 2011-04-22 | 2018-08-14 | Emergent Product Dev Seattle | Proteínas de ligação de antígeno de membrana específico de próstata e composições e métodos relacionados |
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-
2006
- 2006-02-17 CN CN2006800053479A patent/CN101124249B/zh not_active Expired - Fee Related
- 2006-02-17 WO PCT/US2006/005852 patent/WO2006089230A2/en not_active Ceased
- 2006-02-17 US US11/918,153 patent/US20090297438A1/en not_active Abandoned
- 2006-02-17 HR HRP20120709TT patent/HRP20120709T1/hr unknown
- 2006-02-17 AU AU2006214031A patent/AU2006214031A1/en not_active Abandoned
- 2006-02-17 NZ NZ556661A patent/NZ556661A/en not_active IP Right Cessation
- 2006-02-17 PL PL06735489T patent/PL1851250T3/pl unknown
- 2006-02-17 ES ES06735489T patent/ES2386366T3/es active Active
- 2006-02-17 MX MX2007009878A patent/MX2007009878A/es not_active Application Discontinuation
- 2006-02-17 BR BRPI0607757-9A patent/BRPI0607757A2/pt not_active Application Discontinuation
- 2006-02-17 EP EP06735489A patent/EP1851250B1/en active Active
- 2006-02-17 DK DK06735489.4T patent/DK1851250T3/da active
- 2006-02-17 CA CA002598522A patent/CA2598522A1/en not_active Abandoned
- 2006-02-17 JP JP2007556368A patent/JP2008529556A/ja active Pending
- 2006-02-17 PT PT06735489T patent/PT1851250E/pt unknown
- 2006-02-17 KR KR1020077021333A patent/KR20070115967A/ko not_active Withdrawn
-
2007
- 2007-07-19 IL IL184733A patent/IL184733A/en not_active IP Right Cessation
- 2007-07-20 NO NO20073797A patent/NO20073797L/no not_active Application Discontinuation
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2012
- 2012-09-04 CY CY20121100788T patent/CY1113089T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL184733A0 (en) | 2007-12-03 |
| NZ556661A (en) | 2010-10-29 |
| PT1851250E (pt) | 2012-08-27 |
| CA2598522A1 (en) | 2006-08-24 |
| ES2386366T3 (es) | 2012-08-17 |
| PL1851250T3 (pl) | 2012-10-31 |
| EP1851250A2 (en) | 2007-11-07 |
| CY1113089T1 (el) | 2016-04-13 |
| WO2006089230A2 (en) | 2006-08-24 |
| DK1851250T3 (da) | 2012-07-09 |
| EP1851250B1 (en) | 2012-06-06 |
| JP2008529556A (ja) | 2008-08-07 |
| BRPI0607757A2 (pt) | 2009-10-06 |
| CN101124249B (zh) | 2011-06-29 |
| KR20070115967A (ko) | 2007-12-06 |
| IL184733A (en) | 2015-07-30 |
| AU2006214031A1 (en) | 2006-08-24 |
| US20090297438A1 (en) | 2009-12-03 |
| HRP20120709T1 (hr) | 2012-10-31 |
| WO2006089230A3 (en) | 2006-11-16 |
| CN101124249A (zh) | 2008-02-13 |
| MX2007009878A (es) | 2007-10-03 |
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