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NO20072984L - Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for medical treatment - Google Patents

Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for medical treatment

Info

Publication number
NO20072984L
NO20072984L NO20072984A NO20072984A NO20072984L NO 20072984 L NO20072984 L NO 20072984L NO 20072984 A NO20072984 A NO 20072984A NO 20072984 A NO20072984 A NO 20072984A NO 20072984 L NO20072984 L NO 20072984L
Authority
NO
Norway
Prior art keywords
pyrido
pyrimidines
pharmaceutical compositions
medical treatment
compositions useful
Prior art date
Application number
NO20072984A
Other languages
English (en)
Inventor
Steven Cesar Alfons De Jonghe
Eduard Dolusic
Ling-Jie Gao
Piet Andre Maurits M Herdewijn
Wolfgang Eugen Pfleiderer
Original Assignee
4 Aza Ip Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4 Aza Ip Nv filed Critical 4 Aza Ip Nv
Publication of NO20072984L publication Critical patent/NO20072984L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Oppfinnelsen angår substituerte pyrido(3,2-d)pyrimidinderivater ifølge figur, deres farmasøytisk akseptable salter, N-oksider, solvater, prodrugs og enantiomerer med uventet ønskede farmasøytiske egenskaper og som spesielt er svært aktive immunosuppressive midler, og som sådan er nyttige i behandlingen av transplantatrejeksjon og/eller i behandlingen av visse inflammatoriske sykdommer. Disse derivatene er også anvendelige for å forhindre eller behandle kardiovaskulære forstyrrelser, forstyrrelser i sentralnervesystemet, TNF-a-relaterte forstyrrelser, virale sykdommer (inkludert hepatitt C), erektil dysfunksjon og celleproliferative forstyrrelser.
NO20072984A 2004-12-30 2007-06-12 Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for medical treatment NO20072984L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0428475.8A GB0428475D0 (en) 2004-12-30 2004-12-30 Pyrido(3,2-D)pyrimidine derivatives and pharmaceutical compositions useful as medicines for the treatment of autoimmune disorders
US69389905P 2005-06-24 2005-06-24
PCT/EP2005/014187 WO2006069805A2 (en) 2004-12-30 2005-12-29 Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for medical treatment

Publications (1)

Publication Number Publication Date
NO20072984L true NO20072984L (no) 2007-09-10

Family

ID=34131009

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072984A NO20072984L (no) 2004-12-30 2007-06-12 Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for medical treatment

Country Status (10)

Country Link
US (1) US20080004285A1 (no)
EP (1) EP1831217A2 (no)
KR (1) KR20070102693A (no)
CN (1) CN101365699A (no)
AU (1) AU2005321492A1 (no)
CA (1) CA2594241A1 (no)
GB (1) GB0428475D0 (no)
NO (1) NO20072984L (no)
WO (1) WO2006069805A2 (no)
ZA (1) ZA200705281B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
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NO341055B1 (no) * 2005-11-22 2017-08-14 Kudos Pharm Ltd Pyridopyrimidinforbindelser og anvendelse derav,samt farmasøytisk preparat.

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NO341055B1 (no) * 2005-11-22 2017-08-14 Kudos Pharm Ltd Pyridopyrimidinforbindelser og anvendelse derav,samt farmasøytisk preparat.

Also Published As

Publication number Publication date
KR20070102693A (ko) 2007-10-19
AU2005321492A1 (en) 2006-07-06
WO2006069805A3 (en) 2007-01-25
CN101365699A (zh) 2009-02-11
CA2594241A1 (en) 2006-07-06
US20080004285A1 (en) 2008-01-03
WO2006069805A2 (en) 2006-07-06
ZA200705281B (en) 2008-07-30
EP1831217A2 (en) 2007-09-12
GB0428475D0 (en) 2005-02-02

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