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MX2007007032A - Compuestos de aminopirimidina y metodos de uso. - Google Patents

Compuestos de aminopirimidina y metodos de uso.

Info

Publication number
MX2007007032A
MX2007007032A MX2007007032A MX2007007032A MX2007007032A MX 2007007032 A MX2007007032 A MX 2007007032A MX 2007007032 A MX2007007032 A MX 2007007032A MX 2007007032 A MX2007007032 A MX 2007007032A MX 2007007032 A MX2007007032 A MX 2007007032A
Authority
MX
Mexico
Prior art keywords
aminopyrimidine compounds
methods
relates
aminopyrimidine
plk1
Prior art date
Application number
MX2007007032A
Other languages
English (en)
Inventor
Adrian Leonard Smith
Nick A Paras
Gang Liu
Paul Edward Brennan
Frenel Fils Demorin
Daniel Martin Retz
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2007007032A publication Critical patent/MX2007007032A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invencion se refiere a compuestos de aminopirimidina utiles para el tratamiento de enfermedades mediadas por cinasa 1 de tipo polo (Plkl). La invencion tambien se refiere al uso terapeutico de los compuestos de aminopirimidina y composiciones de la misma para el tratamiento de enfermedades asociadas con el crecimiento anormal de la celula y la proliferacion indeseada de la celula.
MX2007007032A 2004-12-17 2005-12-16 Compuestos de aminopirimidina y metodos de uso. MX2007007032A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63660404P 2004-12-17 2004-12-17
PCT/US2005/045863 WO2006066172A1 (en) 2004-12-17 2005-12-16 Aminopyrimidine compounds and methods of use

Publications (1)

Publication Number Publication Date
MX2007007032A true MX2007007032A (es) 2007-07-04

Family

ID=36588221

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007007032A MX2007007032A (es) 2004-12-17 2005-12-16 Compuestos de aminopirimidina y metodos de uso.

Country Status (9)

Country Link
US (2) US7786132B2 (es)
EP (1) EP1831207B1 (es)
JP (1) JP4932735B2 (es)
CN (1) CN101115749B (es)
AU (1) AU2005316312B2 (es)
CA (1) CA2590939C (es)
ES (1) ES2397362T3 (es)
MX (1) MX2007007032A (es)
WO (1) WO2006066172A1 (es)

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BRPI0713187A2 (pt) * 2006-07-20 2012-10-16 Mehmet Kahraman método de inibir rho-quinase, método de tratamento de doença mediada por rho-quinase, composto e composição farmacêutica
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AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
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CN104860900A (zh) * 2014-02-25 2015-08-26 中国药科大学 噻唑类化合物、其制备方法及其在制药中的用途
CN105884711A (zh) * 2014-12-16 2016-08-24 中国药科大学 噻唑类化合物、其制备方法及其在制药中的用途
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SG11201804601TA (en) 2015-12-17 2018-07-30 Arqule Inc Methods for preparing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine
SG11201900689RA (en) 2016-07-29 2019-02-27 Sunovion Pharmaceuticals Inc Compounds and compositions and uses thereof
JP2019523279A (ja) 2016-07-29 2019-08-22 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 化合物および組成物ならびにそれらの使用
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WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
CN112125879A (zh) * 2020-09-29 2020-12-25 浙江永太科技股份有限公司 一种卡格列净中间体2-(4-氟苯基)噻吩的制备方法
CN114133337A (zh) * 2020-12-14 2022-03-04 成都泰蓉生物科技有限公司 一种2-取代的赖氨酸的制备方法
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Also Published As

Publication number Publication date
US20100010014A1 (en) 2010-01-14
US20070185133A1 (en) 2007-08-09
ES2397362T3 (es) 2013-03-06
EP1831207A4 (en) 2010-09-15
CN101115749A (zh) 2008-01-30
WO2006066172A1 (en) 2006-06-22
US7858785B2 (en) 2010-12-28
CA2590939A1 (en) 2006-06-22
JP2008524248A (ja) 2008-07-10
AU2005316312A1 (en) 2006-06-22
EP1831207A1 (en) 2007-09-12
CN101115749B (zh) 2011-06-22
JP4932735B2 (ja) 2012-05-16
US7786132B2 (en) 2010-08-31
AU2005316312B2 (en) 2009-10-22
EP1831207B1 (en) 2012-11-14
CA2590939C (en) 2011-10-18

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