NO20061832L - Karboksamidderivat av amidtype - Google Patents
Karboksamidderivat av amidtypeInfo
- Publication number
- NO20061832L NO20061832L NO20061832A NO20061832A NO20061832L NO 20061832 L NO20061832 L NO 20061832L NO 20061832 A NO20061832 A NO 20061832A NO 20061832 A NO20061832 A NO 20061832A NO 20061832 L NO20061832 L NO 20061832L
- Authority
- NO
- Norway
- Prior art keywords
- halogen
- derivative
- lower alkyl
- amide type
- salts
- Prior art date
Links
- 150000001408 amides Chemical class 0.000 title abstract 2
- 150000003672 ureas Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 229940053202 antiepileptics carboxamide derivative Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrrole Compounds (AREA)
Abstract
Karboksamidderivat av amidtype med generell formel [1]: hvor X er -N= eller -CH=; R1 er halogen, lavere alkyl etc; R2 har formel [2] Y1 og Y2 er like eller forskjellige og er halogen eller en gruppe valgt blant lavere alkyl, lavere alkoksy etc.; og ring A er fenyl etc. Det beskrives også farmakologisk akseptable salter av derivatet. Derivatet og saltene er anvendelige som medisin, særlig som en FXa-inhibitor. hvor X er -N= eller -CH=; R1 er halogen, lavere alkyl etc; R2 har formel [2] Y1 og Y2 er like eller forskjellige og er halogen eller en gruppe valgt blant lavere alkyl, lavere alkoksy etc.; og ring A er fenyl etc. Det beskrives også farmakologisk akseptable salter av derivatet. Derivatet og saltene er anvendelige som medisin, særlig som en FXa-inhibitor.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003334595 | 2003-09-26 | ||
| PCT/JP2004/013892 WO2005030706A1 (ja) | 2003-09-26 | 2004-09-24 | アミド型カルボキサミド誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061832L true NO20061832L (no) | 2006-04-25 |
Family
ID=34386034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061832A NO20061832L (no) | 2003-09-26 | 2006-04-25 | Karboksamidderivat av amidtype |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7375119B2 (no) |
| EP (1) | EP1666455A4 (no) |
| JP (1) | JP4571075B2 (no) |
| KR (1) | KR100740820B1 (no) |
| CN (1) | CN100475777C (no) |
| AR (1) | AR045816A1 (no) |
| AU (1) | AU2004276128B2 (no) |
| BR (1) | BRPI0414460A (no) |
| CA (1) | CA2538072C (no) |
| IL (1) | IL174188A0 (no) |
| MX (1) | MXPA06003382A (no) |
| NO (1) | NO20061832L (no) |
| NZ (1) | NZ546160A (no) |
| RU (1) | RU2307829C2 (no) |
| TW (1) | TW200512181A (no) |
| WO (1) | WO2005030706A1 (no) |
| ZA (1) | ZA200602131B (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7875627B2 (en) | 2004-12-07 | 2011-01-25 | Abbott Laboratories | Thienopyridyl compounds that inhibit vanilloid receptor subtype 1 (VR1) and uses thereof |
| TW200734304A (en) * | 2005-11-08 | 2007-09-16 | Astellas Pharma Inc | Benzene derivative or salt thereof |
| RS52874B (sr) * | 2006-11-15 | 2013-12-31 | Vertex Pharmaceuticals Incorporated | Analozi tiofena za lečenje ili prevenciju infekcija izazvanih flavivirusom |
| KR101107949B1 (ko) | 2007-02-02 | 2012-02-08 | 화이자 프로덕츠 인코포레이티드 | 트라이사이클릭 화합물 및 글루코코르티코이드 수용체 조절자로서의 이들의 용도 |
| EP2070916A1 (de) | 2007-12-10 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | 2-Aryl-thiazol-4-carbonsäureamid-Derivate, deren Herstellung und Verwendung als Arzneimittel |
| EP2070925A1 (de) | 2007-12-10 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | Neue 2-substituierte Tiazol-4-carbonsäureamid-Derivative deren Herstellung und Verwendung als Arzneimittel |
| EP2070924A1 (de) | 2007-12-10 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | Neue 2-Hetarylthiazol-4-carbonsäureamid-Derivative, deren Herstellung und Verwendung als Arzneimittel |
| US8178583B2 (en) * | 2008-12-19 | 2012-05-15 | Hoffmann-La Roche Inc. | Compounds |
| US9186349B2 (en) * | 2009-05-12 | 2015-11-17 | Mallinckrodt Llc | Diaza heterocyclic compounds for phototherapy |
| EP2635559A2 (en) * | 2010-11-01 | 2013-09-11 | Neurotune AG | Neurotrypsin inhibitors |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9306453D0 (en) * | 1993-03-29 | 1993-05-19 | Zeneca Ltd | Heterocyclic derivatives |
| US6313122B1 (en) | 1997-06-26 | 2001-11-06 | Eli Lilly And Company | Antithrombotic agents |
| CN1143855C (zh) * | 1997-12-19 | 2004-03-31 | 舍林公开股份有限公司 | 作为抗凝剂的邻氨基苯甲酰胺衍生物 |
| EP0937711A1 (de) | 1998-02-18 | 1999-08-25 | Roche Diagnostics GmbH | Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
| US6956988B2 (en) * | 1998-08-21 | 2005-10-18 | Avanex Corporation | Optical interleaver |
| ATE272633T1 (de) * | 1998-12-23 | 2004-08-15 | Lilly Co Eli | Aromatische amiden |
| IL155155A0 (en) | 1999-09-17 | 2003-10-31 | Cor Therapeutics Inc | BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa |
| AU2001277731A1 (en) | 2000-08-09 | 2002-02-18 | Welfide Corporation | Fused bicyclic amide compounds and medicinal use thereof |
| EP1379506A2 (en) * | 2000-11-28 | 2004-01-14 | Eli Lilly And Company | Substituted carboxamides |
| US7312235B2 (en) * | 2001-03-30 | 2007-12-25 | Millennium Pharmaceuticals, Inc. | Benzamide inhibitors of factor Xa |
| WO2002079145A1 (en) * | 2001-03-30 | 2002-10-10 | Millennium Pharmaceuticals, Inc. | BENZAMIDE INHIBITORS OF FACTOR Xa |
| IL160693A0 (en) * | 2001-09-21 | 2004-08-31 | Bristol Myers Squibb Co | Lactam-containing compounds and derivatives thereof as factor xa inhibitors |
| WO2003048081A2 (en) * | 2001-12-04 | 2003-06-12 | Bristol-Myers Squibb Company | Glycinamides as factor xa inhibitors |
| DE60330847D1 (de) | 2002-03-28 | 2010-02-25 | Mitsubishi Tanabe Pharma Corp | Benzofuranderivat |
| JP2005104838A (ja) | 2003-01-09 | 2005-04-21 | Tanabe Seiyaku Co Ltd | 縮合フラン化合物 |
-
2004
- 2004-09-03 TW TW093126644A patent/TW200512181A/zh unknown
- 2004-09-24 EP EP04788051A patent/EP1666455A4/en not_active Withdrawn
- 2004-09-24 WO PCT/JP2004/013892 patent/WO2005030706A1/ja not_active Ceased
- 2004-09-24 AR ARP040103460A patent/AR045816A1/es unknown
- 2004-09-24 BR BRPI0414460-0A patent/BRPI0414460A/pt not_active IP Right Cessation
- 2004-09-24 US US10/571,900 patent/US7375119B2/en not_active Expired - Fee Related
- 2004-09-24 JP JP2005514202A patent/JP4571075B2/ja not_active Expired - Fee Related
- 2004-09-24 RU RU2006114055/04A patent/RU2307829C2/ru not_active IP Right Cessation
- 2004-09-24 CN CNB2004800280312A patent/CN100475777C/zh not_active Expired - Fee Related
- 2004-09-24 NZ NZ546160A patent/NZ546160A/en unknown
- 2004-09-24 MX MXPA06003382A patent/MXPA06003382A/es active IP Right Grant
- 2004-09-24 AU AU2004276128A patent/AU2004276128B2/en not_active Ceased
- 2004-09-24 KR KR1020067005726A patent/KR100740820B1/ko not_active Expired - Fee Related
- 2004-09-24 CA CA002538072A patent/CA2538072C/en not_active Expired - Fee Related
-
2006
- 2006-03-08 IL IL174188A patent/IL174188A0/en unknown
- 2006-03-14 ZA ZA200602131A patent/ZA200602131B/xx unknown
- 2006-04-25 NO NO20061832A patent/NO20061832L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2005030706A1 (ja) | 2006-12-07 |
| CN1860097A (zh) | 2006-11-08 |
| BRPI0414460A (pt) | 2006-11-14 |
| US20060287329A1 (en) | 2006-12-21 |
| JP4571075B2 (ja) | 2010-10-27 |
| US7375119B2 (en) | 2008-05-20 |
| CA2538072C (en) | 2009-08-25 |
| EP1666455A1 (en) | 2006-06-07 |
| NZ546160A (en) | 2008-09-26 |
| AU2004276128A1 (en) | 2005-04-07 |
| AR045816A1 (es) | 2005-11-16 |
| WO2005030706A1 (ja) | 2005-04-07 |
| KR100740820B1 (ko) | 2007-07-19 |
| RU2307829C2 (ru) | 2007-10-10 |
| TW200512181A (en) | 2005-04-01 |
| CA2538072A1 (en) | 2005-04-07 |
| KR20060095982A (ko) | 2006-09-05 |
| EP1666455A4 (en) | 2009-02-25 |
| MXPA06003382A (es) | 2006-06-08 |
| IL174188A0 (en) | 2006-08-01 |
| AU2004276128B2 (en) | 2007-11-29 |
| RU2006114055A (ru) | 2006-09-10 |
| CN100475777C (zh) | 2009-04-08 |
| ZA200602131B (en) | 2007-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |