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NO20056169L - 2,4-bis (trifluoroetoksy)pyridin-forbindelse og medikament inneholdende samme - Google Patents

2,4-bis (trifluoroetoksy)pyridin-forbindelse og medikament inneholdende samme

Info

Publication number
NO20056169L
NO20056169L NO20056169A NO20056169A NO20056169L NO 20056169 L NO20056169 L NO 20056169L NO 20056169 A NO20056169 A NO 20056169A NO 20056169 A NO20056169 A NO 20056169A NO 20056169 L NO20056169 L NO 20056169L
Authority
NO
Norway
Prior art keywords
trifluoroethoxy
bis
pyridine compound
same
drug containing
Prior art date
Application number
NO20056169A
Other languages
English (en)
Other versions
NO332545B1 (no
Inventor
Kimiyuki Shibuya
Tadaaki Ohgiya
Takayuki Matsuda
Toru Miura
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Publication of NO20056169L publication Critical patent/NO20056169L/no
Publication of NO332545B1 publication Critical patent/NO332545B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår en 2,4-bis(trifluoretoksy)pyridinforbindelse representert ved formel (1): (hvor x' representerer et fluoratom eller et hydrogenatom), eller et salt derav, og en medisin inneholdende forbindelsen eller saltet som en aktiv bestanddel. Forbindelsen har metabolsk resistens i et humant levermikrosom, god absorberbarhet ved oral adminisfrering, og utmerket ACAT-hemmende aktivitet.
NO20056169A 2003-07-07 2005-12-23 2,4-bis(trifluoroetoksy)pyridin-forbindelse, fremgangsmate for fremstilling, mellomprodukt ved fremstilling, medikament inneholdende samme samt anvendelse av medikamentet for behandling og forebygging av sykdom NO332545B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003192853 2003-07-07
PCT/JP2004/009563 WO2005003119A1 (ja) 2003-07-07 2004-07-06 ２，４−ビス（トリフルオロエトキシ）ピリジン化合物及びこれを含有する医薬

Publications (2)

Publication Number Publication Date
NO20056169L true NO20056169L (no) 2006-01-16
NO332545B1 NO332545B1 (no) 2012-10-22

Family

ID=33562427

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20056169A NO332545B1 (no) 2003-07-07 2005-12-23 2,4-bis(trifluoroetoksy)pyridin-forbindelse, fremgangsmate for fremstilling, mellomprodukt ved fremstilling, medikament inneholdende samme samt anvendelse av medikamentet for behandling og forebygging av sykdom
NO20120857A NO333799B1 (no) 2003-07-07 2012-08-01 Mellomprodukt for syntese av 2,4-bis(trifluoroetoksy)pyridin-forbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20120857A NO333799B1 (no) 2003-07-07 2012-08-01 Mellomprodukt for syntese av 2,4-bis(trifluoroetoksy)pyridin-forbindelser

Country Status (16)

Country Link
US (1) US7223764B2 (no)
EP (1) EP1642899B1 (no)
JP (1) JP4676883B2 (no)
KR (1) KR101048377B1 (no)
CN (3) CN101328152B (no)
AU (1) AU2004254226C1 (no)
CA (1) CA2529207C (no)
DK (1) DK1642899T3 (no)
ES (1) ES2389654T3 (no)
MX (1) MXPA06000296A (no)
MY (1) MY140849A (no)
NO (2) NO332545B1 (no)
NZ (1) NZ544482A (no)
RU (1) RU2346942C2 (no)
TW (1) TWI324600B (no)
WO (1) WO2005003119A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140618A (en) * 2003-02-28 2009-12-31 Kowa Co Method for preparing acid addition salts of polyacidic basic compounds
EP1627875B1 (en) 2003-05-28 2013-07-31 Kowa Co., Ltd. Method for producing cyclic diamine derivative or salt thereof
TWI324600B (en) 2003-07-07 2010-05-11 Kowa Co 2,4-bis (trifluoroethoxy) pyridine compound and drug containing the compound
SG11201913134UA (en) 2017-06-26 2020-01-30 Lunella Biotech Inc Mitoketoscins: mitochondrial-based therapeutics targeting ketone metabolism in cancer cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP624A (en) * 1995-06-06 1997-12-19 Pfizer Substituted n-(indole-2-carbonyl)-b- alanimamides and derivatives as antidiabetic agents.
ATE285402T1 (de) * 1997-05-26 2005-01-15 Kowa Co Neue zyklische diaminverbindungen und heilmittel das diese enthält
JP3790191B2 (ja) * 2002-07-18 2006-06-28 ジヤトコ株式会社 トロイダル型無段変速機
WO2004052861A1 (ja) * 2002-12-12 2004-06-24 Kowa Co., Ltd. ヒドロキシアルキル環状ジアミン化合物
MY140618A (en) * 2003-02-28 2009-12-31 Kowa Co Method for preparing acid addition salts of polyacidic basic compounds
EP1627875B1 (en) * 2003-05-28 2013-07-31 Kowa Co., Ltd. Method for producing cyclic diamine derivative or salt thereof
TWI324600B (en) 2003-07-07 2010-05-11 Kowa Co 2,4-bis (trifluoroethoxy) pyridine compound and drug containing the compound

Also Published As

Publication number Publication date
TW200524904A (en) 2005-08-01
CN101899007A (zh) 2010-12-01
KR20060026417A (ko) 2006-03-23
AU2004254226B2 (en) 2009-01-22
NO20120857L (no) 2006-01-16
WO2005003119A1 (ja) 2005-01-13
CA2529207A1 (en) 2005-01-13
EP1642899B1 (en) 2012-08-15
HK1127862A1 (en) 2009-10-09
MXPA06000296A (es) 2006-04-18
ES2389654T3 (es) 2012-10-30
RU2006103364A (ru) 2006-06-10
CA2529207C (en) 2012-02-21
KR101048377B1 (ko) 2011-07-11
AU2004254226A1 (en) 2005-01-13
NO332545B1 (no) 2012-10-22
DK1642899T3 (da) 2012-09-03
TWI324600B (en) 2010-05-11
MY140849A (en) 2010-01-29
US20050020606A1 (en) 2005-01-27
NO333799B1 (no) 2013-09-16
CN1816542A (zh) 2006-08-09
CN101328152A (zh) 2008-12-24
CN101899007B (zh) 2012-04-25
US7223764B2 (en) 2007-05-29
EP1642899A4 (en) 2009-02-25
JPWO2005003119A1 (ja) 2006-11-09
NZ544482A (en) 2008-05-30
CN101328152B (zh) 2011-06-08
HK1093976A1 (en) 2007-03-16
JP4676883B2 (ja) 2011-04-27
EP1642899A1 (en) 2006-04-05
RU2346942C2 (ru) 2009-02-20
AU2004254226C1 (en) 2009-07-02
CN100404529C (zh) 2008-07-23

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