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NO20055934L - Funksjonelt rekonstituerte virale virusmembraner - Google Patents

Funksjonelt rekonstituerte virale virusmembraner

Info

Publication number
NO20055934L
NO20055934L NO20055934A NO20055934A NO20055934L NO 20055934 L NO20055934 L NO 20055934L NO 20055934 A NO20055934 A NO 20055934A NO 20055934 A NO20055934 A NO 20055934A NO 20055934 L NO20055934 L NO 20055934L
Authority
NO
Norway
Prior art keywords
membranes
reconstituted viral
viral virus
functionally reconstituted
viral
Prior art date
Application number
NO20055934A
Other languages
English (en)
Inventor
Antonius Johannes Hen Stegmann
Jan Christiaan Wilschut
Johannes Henricus Garar Berkum
Original Assignee
Bestewil Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bestewil Holding Bv filed Critical Bestewil Holding Bv
Publication of NO20055934L publication Critical patent/NO20055934L/no

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y10S977/907—Liposome

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Sammendrag Det beskrives vaksiner rettet mot antigener så som membranproteiner fra patogener eller tumorceller. Oppfinnelsen vedrører videre framgangsmåter for å danne · rekonstituerte virale membraner, med membranfusjonsaktivitet, som er lipidbisjiktmembraner fortrinnsvis inneholdende naturlige lipider av et virus, et viralt fusjonsprotein, en eller flere valgfritt ytterligere antigen og likeledes amfifile adjuvanser. Farmasøytiske materialer omfattende slike rekonstituerte virale membraner er også en del av oppfinnelsen.
NO20055934A 2003-06-19 2005-12-14 Funksjonelt rekonstituerte virale virusmembraner NO20055934L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL0300450 2003-06-19
PCT/NL2004/000437 WO2004110486A1 (en) 2003-06-19 2004-06-18 Functionally reconstituted viral membranes containing adjuvant

Publications (1)

Publication Number Publication Date
NO20055934L true NO20055934L (no) 2006-03-20

Family

ID=33550371

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055934A NO20055934L (no) 2003-06-19 2005-12-14 Funksjonelt rekonstituerte virale virusmembraner

Country Status (20)

Country Link
US (1) US7618641B2 (no)
EP (2) EP2368576B1 (no)
JP (1) JP4685005B2 (no)
KR (1) KR101225199B1 (no)
CN (1) CN100556454C (no)
AR (1) AR056245A1 (no)
AU (1) AU2004246974B2 (no)
BR (1) BRPI0411519A (no)
CA (1) CA2527735C (no)
DK (2) DK1633395T3 (no)
ES (2) ES2536689T3 (no)
IL (1) IL172584A (no)
MX (1) MXPA05013929A (no)
NO (1) NO20055934L (no)
PL (2) PL1633395T3 (no)
RU (1) RU2348428C2 (no)
TW (1) TWI329130B (no)
UA (1) UA87269C2 (no)
WO (1) WO2004110486A1 (no)
ZA (1) ZA200509907B (no)

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AR059972A1 (es) * 2006-03-22 2008-05-14 Solvay Pharm Bv Administracion intranasal o inhalacional de virosomas
TWI397419B (zh) * 2006-03-22 2013-06-01 Abbott Biologicals Bv 病毒顆粒的鼻內或吸入給藥
US8535683B2 (en) 2006-03-22 2013-09-17 Abbott Biologicals B.V. Intranasal or inhalational administration of virosomes
US8916164B2 (en) * 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
EP2058002A1 (en) 2007-10-31 2009-05-13 Bestewil Holding B.V. Reconstituted respiratory syncytial virus membranes and use as respiratory syncytial virus vaccine
EA025275B1 (ru) 2009-02-06 2016-12-30 Майметикс Корпорейшн Способ, терапевтическая композиция, вакцинная комбинация и набор для терапевтического или профилактического лечения вич
KR101756202B1 (ko) 2009-02-06 2017-07-10 마이메틱스 코포레이션 신규한 ｇｐ41 항원
EP2549990A1 (en) * 2010-03-23 2013-01-30 Irm Llc Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.
WO2011128720A1 (en) 2010-04-14 2011-10-20 Mymetics Corporation Trans-activator of transcription protein
CN103179977B (zh) 2010-08-27 2016-10-26 潘塔希生物科学股份有限公司 治疗前列腺癌的免疫治疗方法
US20130259928A1 (en) * 2010-09-30 2013-10-03 Franvax S.R.L. Generation of virosome particles
RU2440140C1 (ru) * 2010-12-09 2012-01-20 Иосиф Григорьевич Атабеков Иммуногенная композиция, содержащая чужеродные антигены на поверхности сферических носителей, полученных при термической денатурации спиральных вирусов
RU2441667C1 (ru) * 2010-12-09 2012-02-10 Иосиф Григорьевич Атабеков Новый тип частиц-носителей (платформ) для получения активных комплексов
EP3016679B1 (en) * 2013-07-02 2019-03-27 Janssen Vaccines & Prevention B.V. Method for preparing virosomes
WO2016039620A2 (en) 2014-09-12 2016-03-17 Bestewil Holding B.V. Respiratory syncytial virus virosomes
CA2960948C (en) 2014-09-12 2023-04-04 Bestewil Holding B.V. Methods for providing adjuvanted virosomes and adjuvanted virosomes obtainable thereby
WO2016080830A2 (en) 2014-11-18 2016-05-26 Pantarhei Bioscience B.V. Immunotherapeutic method for treating pancreatic cancer
US11819542B2 (en) 2017-10-31 2023-11-21 Pantarhei Bioscience B.V. Immunotherapeutic method for treating lung cancer by administering a polypeptide comprising an epitope of hZP3
WO2020048924A1 (en) 2018-09-03 2020-03-12 Laboratoire Hra-Pharma Zp3 fragments in immunotherapy of ovarian cancer
US11523988B2 (en) 2018-11-29 2022-12-13 Catalent U.K. Swindon Zydis Limited Oral dispersible vaccine comprising virosomes
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WO2021207303A1 (en) * 2020-04-07 2021-10-14 Alsatech, Inc. Immune stimulation against coronavirus infections
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WO2023237726A1 (en) 2022-06-10 2023-12-14 Pantarhei Oncology B.V. An intracellular tumor-specific variant of human zona pellucida glycoprotein 3 and nucleic acids coding therefor for use in the treatment of cancer
CN120076824A (zh) * 2022-10-25 2025-05-30 宁波明亦生物科技有限公司 质膜透化灭活口服疫苗

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Also Published As

Publication number Publication date
AR056245A1 (es) 2007-10-03
KR20060030047A (ko) 2006-04-07
ZA200509907B (en) 2006-11-29
DK2368576T3 (en) 2015-05-18
US7618641B2 (en) 2009-11-17
RU2348428C2 (ru) 2009-03-10
IL172584A (en) 2010-11-30
JP2006527598A (ja) 2006-12-07
EP1633395B1 (en) 2012-08-01
PL1633395T3 (pl) 2012-12-31
CN1805754A (zh) 2006-07-19
JP4685005B2 (ja) 2011-05-18
KR101225199B1 (ko) 2013-01-23
RU2006101394A (ru) 2006-06-10
DK1633395T3 (da) 2012-10-29
EP2368576B1 (en) 2015-02-25
EP2368576A2 (en) 2011-09-28
US20060193873A1 (en) 2006-08-31
AU2004246974A1 (en) 2004-12-23
EP1633395A1 (en) 2006-03-15
CA2527735C (en) 2014-12-16
BRPI0411519A (pt) 2006-08-01
EP2368576A3 (en) 2012-03-28
MXPA05013929A (es) 2006-03-08
CN100556454C (zh) 2009-11-04
CA2527735A1 (en) 2004-12-23
ES2536689T3 (es) 2015-05-27
WO2004110486A1 (en) 2004-12-23
ES2390454T3 (es) 2012-11-13
UA87269C2 (ru) 2009-07-10
TW200510538A (en) 2005-03-16
AU2004246974B2 (en) 2010-05-06
PL2368576T3 (pl) 2015-12-31
TWI329130B (en) 2010-08-21
IL172584A0 (en) 2006-04-10

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