[go: up one dir, main page]

NO20055459L - Prosesser - Google Patents

Prosesser

Info

Publication number
NO20055459L
NO20055459L NO20055459A NO20055459A NO20055459L NO 20055459 L NO20055459 L NO 20055459L NO 20055459 A NO20055459 A NO 20055459A NO 20055459 A NO20055459 A NO 20055459A NO 20055459 L NO20055459 L NO 20055459L
Authority
NO
Norway
Prior art keywords
genes
gene
responsive
processes
sets
Prior art date
Application number
NO20055459A
Other languages
English (en)
Other versions
NO20055459D0 (no
Inventor
Takashi Tsuruo
Yusuke Nakamura
Saburo Sone
Masahiro Fukuoka
Original Assignee
Univ Tokyo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0312451A external-priority patent/GB0312451D0/en
Priority claimed from GB0322636A external-priority patent/GB0322636D0/en
Priority claimed from GB0327132A external-priority patent/GB0327132D0/en
Application filed by Univ Tokyo filed Critical Univ Tokyo
Publication of NO20055459D0 publication Critical patent/NO20055459D0/no
Publication of NO20055459L publication Critical patent/NO20055459L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Pulmonology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Oppfinnelsen vedrører et sett isolerte markørgener omfattende minst ett gen identifisert ved at det har forskjeilig ekspresjon i pasienter som er responssive og ikke-responssive til en erbB reseptor tyrosinkinase inhibitor, hvor gensettet omfatter en eller flere gener valgt fra i det minste gruppen som består av de 51 genene opplistet hen, inkludert genspesifikke oligonukleotider derivert fra genene, og bruk av slike sett til diagnostiske anvendelser.
NO20055459A 2003-05-30 2005-11-18 Prosesser NO20055459L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0312451A GB0312451D0 (en) 2003-05-30 2003-05-30 Process
GB0322636A GB0322636D0 (en) 2003-09-26 2003-09-26 Process
GB0327132A GB0327132D0 (en) 2003-11-21 2003-11-21 Process
PCT/GB2004/002316 WO2005049829A1 (en) 2003-05-30 2004-06-01 Process

Publications (2)

Publication Number Publication Date
NO20055459D0 NO20055459D0 (no) 2005-11-18
NO20055459L true NO20055459L (no) 2006-02-27

Family

ID=34623472

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055459A NO20055459L (no) 2003-05-30 2005-11-18 Prosesser

Country Status (12)

Country Link
US (1) US20060252056A1 (no)
EP (2) EP2348110B1 (no)
JP (2) JP4724657B2 (no)
KR (1) KR101126560B1 (no)
AU (1) AU2004291709C1 (no)
BR (1) BRPI0410634A (no)
CA (1) CA2527680A1 (no)
IL (1) IL172029A (no)
MX (1) MXPA05012939A (no)
NO (1) NO20055459L (no)
NZ (1) NZ543234A (no)
WO (1) WO2005049829A1 (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4724657B2 (ja) * 2003-05-30 2011-07-13 アストラゼネカ ユーケー リミテッド プロセス
US7700299B2 (en) * 2005-08-12 2010-04-20 Hoffmann-La Roche Inc. Method for predicting the response to a treatment
US8129114B2 (en) 2005-08-24 2012-03-06 Bristol-Myers Squibb Company Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
JP2007135581A (ja) * 2005-10-20 2007-06-07 Japan Science & Technology Agency 自己免疫性血小板減少性紫斑病（ｉｔｐ）患者の血液細胞特異的遺伝子群
FI121236B (fi) * 2006-01-18 2010-08-31 Licentia Oy Menetelmä asbestialtistukseen liittyvien keuhkosyöpien tunnistamiseksi
US8138167B2 (en) 2006-02-10 2012-03-20 Oncotherapy Science, Inc. Methods for treating lung cancers
WO2007099852A1 (ja) * 2006-02-23 2007-09-07 National University Corporation Kanazawa University 固形癌のチロシンキナーゼ阻害剤に対する感受性を検査する方法及び検査キット
WO2007101122A2 (en) * 2006-02-24 2007-09-07 University Of Chicago Methods and compositions involving slc17a1
WO2007123462A1 (en) 2006-04-25 2007-11-01 Shengyuan Xu A protein, an antibody and measurement of the protein
EP2392673A1 (en) 2006-06-02 2011-12-07 GlaxoSmithKline Biologicals S.A. Method for identifying whether a patient will be responder or not to immunotherapy based on the differential expression of the FOXP3 gene
JP5656406B2 (ja) * 2006-11-28 2015-01-21 ユースリー ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツングＵ３ Ｐｈａｒｍａ ＧｍｂＨ 治療効力を予測するためのマーカーとしての活性化ｈｅｒ３
WO2008070663A2 (en) * 2006-12-04 2008-06-12 Abbott Laboratories Companion diagnostic assays for cancer therapy
AU2008250033A1 (en) 2007-05-11 2008-11-20 Enzon Pharmaceuticals, Inc. RNA antagonist compounds for the modulation of HER3
BRPI0815413A2 (pt) * 2007-08-14 2019-02-26 F. Hoffmann-La Roche Ag marcador preditivo para tratamento inibidor de egfr
US20110230506A1 (en) * 2007-08-14 2011-09-22 Paul Delmar Predictive marker for egfr inhibitor treatment
MX2010001578A (es) * 2007-08-14 2010-03-15 Hoffmann La Roche Marcador predictivo para tratamiento con el inhibidor del receptor del factor de crecimiento epidermico.
WO2009021683A2 (en) * 2007-08-14 2009-02-19 F. Hoffmann-La Roche Predictive marker for egfr inhibitor treatment
US20110212979A1 (en) * 2007-08-14 2011-09-01 Paul Delmar Predictive marker for egfr inhibitor treatment
AU2008286406A1 (en) * 2007-08-14 2009-02-19 F. Hoffmann-La Roche Ag Predictive markers for EGFR inhibitor treatment
JP2010535517A (ja) * 2007-08-14 2010-11-25 エフ．ホフマン−ラ ロシュ アーゲー Ｅｇｆｒ阻害因子治療のための予測マーカー
MX2010001570A (es) * 2007-08-14 2010-03-15 Hoffmann La Roche Marcador predictivo para tratamiento con el inhibidor del receptor del factor de crecimiento epidermico.
JP5368445B2 (ja) 2007-08-14 2013-12-18 エフ．ホフマン−ラ ロシュ アーゲー Ｅｇｆｒ阻害因子治療のための予測マーカー
JP2010535520A (ja) * 2007-08-14 2010-11-25 エフ．ホフマン−ラ ロシュ アーゲー Ｅｇｆｒ阻害因子治療のための予測マーカー
WO2010015535A1 (en) * 2008-08-05 2010-02-11 F. Hoffmann-La Roche Ag Predictive marker for egfr inhibitor treatment
GB0904957D0 (en) * 2009-03-23 2009-05-06 Univ Erasmus Medical Ct Tumour gene profile
EP2239578A1 (en) * 2009-04-10 2010-10-13 PamGene B.V. Method for determining the survival prognosis of patients suffering from non-small cell lung cancer (NSCLC)
US20120095030A1 (en) * 2009-04-17 2012-04-19 The Translational Genomics Research Institute Methods and kits to predict therapeutic outcome of tyrosine kinase inhibitors
GB0917457D0 (en) 2009-10-06 2009-11-18 Glaxosmithkline Biolog Sa Method
TW201302793A (zh) 2010-09-03 2013-01-16 Glaxo Group Ltd 新穎之抗原結合蛋白
US20140249150A1 (en) * 2011-10-13 2014-09-04 Agios Pharmaceuticals, Inc Activators of pyruvate kinase m2 and methods of treating disease
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與ｗｎｔ抑制劑相關之標記
US10509034B2 (en) 2013-11-05 2019-12-17 Agency For Science, Technology And Research Bladder carcinoma biomarkers

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU661533B2 (en) 1992-01-20 1995-07-27 Astrazeneca Ab Quinazoline derivatives
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
ES2332984T3 (es) 1995-03-30 2010-02-16 Pfizer Products Inc. Derivados de quinazolinas.
GB9508538D0 (en) 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
ES2172670T3 (es) 1995-07-06 2002-10-01 Novartis Ag Pirrolpirimidinas y procedimientos para su preparacion.
US5760041A (en) 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
GB9603095D0 (en) 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
NZ332119A (en) 1996-04-12 2001-08-31 Warner Lambert Co Quinazoline compounds which are irreversible inhibitors of tyrosine kinases
US6002008A (en) 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
EP0980244B1 (en) 1997-05-06 2003-06-04 Wyeth Holdings Corporation Use of quinazoline compounds for the treatment of polycystic kidney disease
TW436485B (en) 1997-08-01 2001-05-28 American Cyanamid Co Substituted quinazoline derivatives
WO1999024037A1 (en) 1997-11-06 1999-05-20 American Cyanamid Company Use of quinazoline derivatives as tyrosine kinase inhibitors for treating colonic polyps
RS49779B (sr) 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
MEP42008A (en) 1998-04-29 2011-02-10 Osi Farmaceuticals Inc N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
CA2349721A1 (en) 1998-11-19 2000-06-02 Warner-Lambert Company N-¬4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl|-acrylamide, an irreversible inhibitor of tyrosine kinases
JP2000287680A (ja) * 1999-04-09 2000-10-17 Sentan Kagaku Gijutsu Incubation Center:Kk 未成熟肝細胞を成熟肝細胞へ分化させる方法
WO2001004111A1 (en) 1999-07-09 2001-01-18 Glaxo Group Limited Anilinoquinazolines as protein tyrosine kinase inhibitors
US7194269B2 (en) 2000-10-30 2007-03-20 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Industry Method and wireless communication hub for data communications
US7189507B2 (en) * 2001-06-18 2007-03-13 Pdl Biopharma, Inc. Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
AU2002355963A1 (en) * 2001-08-16 2003-03-03 Genzyme Corporation Molecular characteristics of non-small cell lung cancer
WO2003040317A2 (en) * 2001-11-02 2003-05-15 Pfizer Products Inc. Lung cancer therapeutics and diagnostics
JP2006519620A (ja) * 2003-03-04 2006-08-31 アークチュラス バイオサイエンス，インコーポレイティド 乳がんにおけるｅｒ状態の弁別特性
JP4724657B2 (ja) * 2003-05-30 2011-07-13 アストラゼネカ ユーケー リミテッド プロセス

Also Published As

Publication number Publication date
JP5217010B2 (ja) 2013-06-19
JP2006526420A (ja) 2006-11-24
EP2348110A1 (en) 2011-07-27
KR101126560B1 (ko) 2012-04-05
EP1633870A1 (en) 2006-03-15
JP4724657B2 (ja) 2011-07-13
EP1633870B1 (en) 2013-03-27
JP2011167188A (ja) 2011-09-01
EP2348110B1 (en) 2013-03-27
NZ543234A (en) 2009-04-30
IL172029A (en) 2011-06-30
KR20060002012A (ko) 2006-01-06
MXPA05012939A (es) 2006-05-17
AU2004291709C1 (en) 2010-03-11
NO20055459D0 (no) 2005-11-18
AU2004291709B2 (en) 2009-09-10
AU2004291709A1 (en) 2005-06-02
WO2005049829A1 (en) 2005-06-02
US20060252056A1 (en) 2006-11-09
BRPI0410634A (pt) 2006-06-13
CA2527680A1 (en) 2005-06-02

Similar Documents

Publication Publication Date Title
NO20055459L (no) Prosesser
WO2008109142A3 (en) Pirna and uses related thereto
WO2005029037A3 (en) Selective modulation of tlr gene expression
WO2007053719A8 (en) Chemically cleavable 3'-o-allyl-dntp-allyl-fluorophore fluorescent nucleotide analogues and related methods
AR059433A1 (es) Identificacion y uso de genes blanco para el control de nematodos parasitos de plantas
NZ585327A (en) Lna antagonists targeting the androgen receptor
DE60329030D1 (de) Melanocortin-rezeptormodulatoren
UY28103A1 (es) Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
WO2007118198A3 (en) 2-METHYLENE-1α,25-DIHYDROXY-19,21-DINORVITAMIN D3 ANALOGS AND USES THEREOF
WO2008035207A3 (en) 2-methylene-1alpha-hydroxy-19,21-dinorvitamin d3 analogs and uses thereof
PL375398A1 (en) Immunostimulatory nucleic acids
NO20082709L (no) Kjemiske forbindelser
MX362199B (es) Compuestos y composiciones de poliglicerilo cationicos.
WO2009061941A3 (en) Baseless nucleotide analogues and uses thereof
NO20065946L (no) DPP-IV-inhibitorer
NO20083845L (no) 2,4-diaminopyrimidiner som celle-cyklus kinase inhibitorer
NO20054083L (no) Nye sammenkoblede triazoloner og deres anvendelse
GB0612721D0 (en) Organic compounds
EP1578359A4 (en) COMBINATIVE LIBRARIES WITH AUTOINDUCER ANALOGU, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHOD OF USE THEREOF
TW200510333A (en) Benzimidazole compounds
BRPI0512352A (pt) 3-aminociclopentanocarboxamidas como moduladores de receptores de quimiocinas
MX2009000654A (es) Medios para inhibir la expresion de la cinasa de proteina 3.
BRPI0514327A (pt) compostos triazolopiridina
BR112018017316A2 (pt) compostos e métodos para a síntese de 5-(n-protegido-triptaminocarboxiamida)-2?-desoxiuridina fosforamidato para incorporação em uma sequência nucleica
ATE439361T1 (de) 7h-pyridoä3,4-düpyrimidin-8-one, ihre herstellung und ihre verwendung als proteinkinaseinhibitoren

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application