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NO20055445L - Anvendelse av en blanding for fremstilling av et medikament for perioperativt a hemme smerte, betennelse og/eller spasme, og en losning for perioperativt a hemme smerte, betennelse og/eller spasme - Google Patents

Anvendelse av en blanding for fremstilling av et medikament for perioperativt a hemme smerte, betennelse og/eller spasme, og en losning for perioperativt a hemme smerte, betennelse og/eller spasme

Info

Publication number
NO20055445L
NO20055445L NO20055445A NO20055445A NO20055445L NO 20055445 L NO20055445 L NO 20055445L NO 20055445 A NO20055445 A NO 20055445A NO 20055445 A NO20055445 A NO 20055445A NO 20055445 L NO20055445 L NO 20055445L
Authority
NO
Norway
Prior art keywords
spasm
inflammation
pain
inhibiting pain
agents
Prior art date
Application number
NO20055445A
Other languages
English (en)
Inventor
Gregory A Demopulos
Pamela Anne Pierce
Jeffrey M Herz
Original Assignee
Omeros Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20055445L publication Critical patent/NO20055445L/no
Application filed by Omeros Corp filed Critical Omeros Corp

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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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Abstract

Det beskrives en anvendelse av en blanding i fremstillingen av et medikament for peri-operativt å hemme smerte og betennelse og/eller spasme ved en vaskulær struktur under en intravaskulær prosedyre, ved under prosedyren å tilføre blandingen lokalt til den vaskulære strukturen, eventuelt der medikamentet er, for kontinuerlig å skylle ut strukturen med løsningen under prosedyren, der blandingen omfatter en fortynnet løsning av et flertall av hemmende midler utvalgt fra smerte/ betennelseshemmende midler og spasmehemmende midler i en fysiologisk flytende bærer, der de ulike midler blir utvalgt fra en rekke klasser av midler som virker gjennom forskjellige molekylære mekanismer på ulike molekylære mål som medierer smerte og betennelse og/eller spasme, og der midlene kollektivt er effektive for å hemme smerte og betennelse og/eller spasme ved den vaskulære struktur, hvor hvert middel er inkludert i en konsentrasjon på ikke mer enn 1 00 000 nanomolar.
NO20055445A 1994-12-12 2005-11-17 Anvendelse av en blanding for fremstilling av et medikament for perioperativt a hemme smerte, betennelse og/eller spasme, og en losning for perioperativt a hemme smerte, betennelse og/eller spasme NO20055445L (no)

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US35377594A 1994-12-12 1994-12-12
PCT/US1995/016028 WO1996019233A2 (en) 1994-12-12 1995-12-12 Irrigation solution and method for inhibition of pain, inflammation and spasm

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EP2301562B1 (en) 2013-04-17
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US20080096948A1 (en) 2008-04-24
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CA2206119A1 (en) 1996-06-27
US5858017A (en) 1999-01-12
WO1996019233A3 (en) 1996-09-19
US20080167388A1 (en) 2008-07-10
DE69534341D1 (de) 2005-09-01
RU2180852C2 (ru) 2002-03-27
ES2421306T3 (es) 2013-08-30
EP0799051B1 (en) 2005-07-27
MX9703988A (es) 1998-02-28
ATE300308T1 (de) 2005-08-15
US5860950A (en) 1999-01-19
EP2301562A1 (en) 2011-03-30
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ES2377126T3 (es) 2012-03-22
DE69534341T2 (de) 2006-05-24
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JP2012184274A (ja) 2012-09-27
CN1175213A (zh) 1998-03-04
US5800385A (en) 1998-09-01
EP0799051A2 (en) 1997-10-08
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