[go: up one dir, main page]

NO20053125D0 - Rekombinant koppevirus omfattende i det minste to kukoppe-ati-promotere. - Google Patents

Rekombinant koppevirus omfattende i det minste to kukoppe-ati-promotere.

Info

Publication number
NO20053125D0
NO20053125D0 NO20053125A NO20053125A NO20053125D0 NO 20053125 D0 NO20053125 D0 NO 20053125D0 NO 20053125 A NO20053125 A NO 20053125A NO 20053125 A NO20053125 A NO 20053125A NO 20053125 D0 NO20053125 D0 NO 20053125D0
Authority
NO
Norway
Prior art keywords
smallpox
recombinant
seq
ati
virus
Prior art date
Application number
NO20053125A
Other languages
English (en)
Norwegian (no)
Other versions
NO20053125L (no
Inventor
Paul Howley
Sonja Leyrer
Original Assignee
Bavarian Nordic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bavarian Nordic As filed Critical Bavarian Nordic As
Publication of NO20053125L publication Critical patent/NO20053125L/no
Publication of NO20053125D0 publication Critical patent/NO20053125D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/863Poxviral vectors, e.g. entomopoxvirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/275Poxviridae, e.g. avipoxvirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/60Vector systems having a special element relevant for transcription from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20053125A 2002-11-25 2005-06-24 Rekombinant koppevirus omfattende i det minste to kukoppe-ati-promotere. NO20053125D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200201814 2002-11-25
PCT/EP2003/012610 WO2004048582A2 (en) 2002-11-25 2003-11-12 Recombinant poxvirus comprising at least two cowpox ati promoters

Publications (2)

Publication Number Publication Date
NO20053125L NO20053125L (no) 2005-06-24
NO20053125D0 true NO20053125D0 (no) 2005-06-24

Family

ID=32337938

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053125A NO20053125D0 (no) 2002-11-25 2005-06-24 Rekombinant koppevirus omfattende i det minste to kukoppe-ati-promotere.

Country Status (21)

Country Link
US (1) US7300658B2 (de)
EP (1) EP1567653B1 (de)
JP (1) JP2006515170A (de)
KR (1) KR20050083839A (de)
CN (1) CN1717488A (de)
AT (1) ATE365220T1 (de)
AU (1) AU2003293675B2 (de)
CA (1) CA2501168A1 (de)
CY (1) CY1106883T1 (de)
DE (1) DE60314541T2 (de)
DK (1) DK1567653T3 (de)
EA (1) EA012723B1 (de)
ES (1) ES2288634T3 (de)
IL (1) IL167844A (de)
MX (1) MXPA05005549A (de)
NO (1) NO20053125D0 (de)
NZ (1) NZ540156A (de)
PL (1) PL375740A1 (de)
PT (1) PT1567653E (de)
UA (1) UA85379C2 (de)
WO (1) WO2004048582A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002231639B2 (en) * 2000-11-23 2007-01-04 Bavarian Nordic A/S Modified vaccinia ankara virus variant
IL164172A0 (en) * 2002-05-16 2005-12-18 Bavarian Nordic As Intergenic regions as insertion sites in the genome of modified vaccinia virus ankara (mva)
US7501127B2 (en) 2002-05-16 2009-03-10 Bavarian Nordic A/S Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara
WO2008100292A2 (en) 2006-10-16 2008-08-21 Genelux Corporation Modified vaccinia virus strains for use in diagnostic and therapeutic methods
WO2009152969A1 (en) * 2008-06-20 2009-12-23 Bavarian Nordic A/S Recombinant modified vaccinia virus measles vaccine
ES2618103T3 (es) * 2008-11-21 2017-06-20 Bavarian Nordic A/S Vector que comprende múltiples secuencias de nucleótidos homólogas
US8394385B2 (en) * 2009-03-13 2013-03-12 Bavarian Nordic A/S Optimized early-late promoter combined with repeated vaccination favors cytotoxic T cell response against recombinant antigen in MVA vaccines
US9567331B2 (en) 2011-11-15 2017-02-14 Trustees Of Boston University Pyridopyrimidinone inhibitors of viruses
WO2016115116A1 (en) 2015-01-12 2016-07-21 Geovax, Inc. Compositions and methods for generating an immune response to a hemorrhagic fever virus
KR20160140075A (ko) * 2015-05-29 2016-12-07 코오롱생명과학 주식회사 폭스바이러스 유래 프로모터 및 이를 포함하는 벡터
FR3042121A1 (fr) 2015-10-08 2017-04-14 Jean-Marc Limacher Composition anti-tumorale
WO2017089307A1 (en) * 2015-11-24 2017-06-01 Glaxosmithkline Intellectual Property Development Limited Transient transfection method for retroviral production
WO2017089308A1 (en) * 2015-11-24 2017-06-01 Glaxosmithkline Intellectual Property Development Limited Stable cell lines for retroviral production
PL3402802T3 (pl) 2016-01-08 2023-06-05 Geovax, Inc. Kompozycje i sposoby generowania odpowiedzi immunologicznej względem antygenu powiązanego z guzem nowotworowym
US20190030157A1 (en) 2016-02-03 2019-01-31 Geovax Inc. Compositions and Methods for Generating an Immune Response to a Flavivirus
JP7023929B2 (ja) * 2016-08-09 2022-02-22 シティ・オブ・ホープ キメラポックスウイルス組成物及びその使用
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
FR3160186A1 (fr) 2024-03-13 2025-09-19 Odimma Therapeutics Vecteur non-viral pour transcription augmentee

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443964A (en) * 1987-08-10 1995-08-22 Duke University Poxvirus insertion/expression vector
US5759841A (en) * 1990-11-20 1998-06-02 Virogenetics Corporation Immunological composition of measles virus utilizing recombinant poxvirus
UA68327C2 (en) * 1995-07-04 2004-08-16 Gsf Forschungszentrum Fur Unwe A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals
US6869793B2 (en) * 1996-09-24 2005-03-22 Bavarian Nordic Research Institute Recombinant MVA virus expressing dengue virus antigens, and the use thereof in vaccines
JP5639736B2 (ja) * 1999-05-28 2014-12-10 ヘルムホルツ・ツェントルム・ミュンヒェン・ドイチェス・フォルシュンクスツェントルム・フューア・ゲズントハイト・ウント・ウムベルト(ゲーエムベーハー)Helmholtz Zentrum MuenchenDeutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH) ポックスウイルスゲノムへの異種遺伝子の組込みのためのベクター
ATE373721T1 (de) 2000-08-29 2007-10-15 Wyeth Corp Verpackung von replikon-partikeln eines positiv- strängigen rna-virus

Also Published As

Publication number Publication date
DK1567653T3 (da) 2007-10-15
NO20053125L (no) 2005-06-24
AU2003293675B2 (en) 2009-04-23
WO2004048582A2 (en) 2004-06-10
WO2004048582A3 (en) 2004-08-12
MXPA05005549A (es) 2005-08-16
EP1567653B1 (de) 2007-06-20
UA85379C2 (ru) 2009-01-26
EP1567653A2 (de) 2005-08-31
CY1106883T1 (el) 2012-09-26
DE60314541T2 (de) 2008-02-28
NZ540156A (en) 2006-11-30
PT1567653E (pt) 2007-10-01
CN1717488A (zh) 2006-01-04
PL375740A1 (en) 2005-12-12
US20060153874A1 (en) 2006-07-13
IL167844A (en) 2011-03-31
KR20050083839A (ko) 2005-08-26
CA2501168A1 (en) 2004-06-10
ES2288634T3 (es) 2008-01-16
EA012723B1 (ru) 2009-12-30
US7300658B2 (en) 2007-11-27
DE60314541D1 (de) 2007-08-02
EA200500879A1 (ru) 2005-10-27
JP2006515170A (ja) 2006-05-25
AU2003293675A1 (en) 2004-06-18
ATE365220T1 (de) 2007-07-15

Similar Documents

Publication Publication Date Title
CY1106883T1 (el) Ανασυνδυασμενος ιος ευλογιας που περιεχει τουλαχιστον δυο υποκινητες ατι ιου ευλογιας αγελαδας.
UA82998C2 (ru) Экспрессия генов в модифицированном вирусе коровьей оспы ankara с использованием коровьего поксвирусного промотора аті
ES2800623T3 (es) Promotor PR13.5 para respuestas contundentes de células T y anticuerpos
RU98101904A (ru) Рекомбинантный вирус mva и его использование
US6869793B2 (en) Recombinant MVA virus expressing dengue virus antigens, and the use thereof in vaccines
IL204539A (en) Foxvirus virus containing defective genes and a losing gene
KR20040108798A (ko) 변형 백시니아 바이러스 안카라(mva)의 게놈내삽입부위로서의 유전자내 영역
US11286500B2 (en) Recombinant Orf virus vector
MXPA02011545A (es) Virus del sindrome respiratorio y reproductor porcino (peesv), vacuna recombinante para el virus de la viruela.
MX2022010588A (es) Vacuna basada en poxvirus recombinantes contra el virus sars-cov-2.
JP5952112B2 (ja) ポックスウイルスまたは他の感染性因子に対する免疫の急速な誘導に改変ポックスウイルスを使用する方法
AU2002337083A1 (en) Vaccinia virus mva-e3l-knockout-mutants and use thereof
IL164179A0 (en) Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter
JPWO2021154828A5 (de)
CA2430115A1 (en) Recombinant rsv virus expression systems and vaccines
DE60117053D1 (de) Herstellung rekombinanter künstlicher hefe-chromosome, welche das genom des humanen cytomegalovirus enthalten
CN101142319B (zh) 基于使用修饰安卡拉痘苗病毒的疫苗
NZ512341A (en) Polynucleotides between 15 and 100 base pairs in length coding for parapoxvirus ovis (PPVO)/vaccinia virus recombinant (VVOV) viral genome fragments
JP2009232836A5 (de)
BR0316553A (pt) Poxvìrus recombinante que compreende pelo menos dois promotores ati de varìola bovina
WO2024259078A3 (en) Anti-tick vaccines and methods of use thereof
DK200201813A (da) Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application