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NO20053986L - Sammensetninger og fremgangsmater for a behandle cancer anvendende IGSF9 og LIV-1. - Google Patents

Sammensetninger og fremgangsmater for a behandle cancer anvendende IGSF9 og LIV-1.

Info

Publication number
NO20053986L
NO20053986L NO20053986A NO20053986A NO20053986L NO 20053986 L NO20053986 L NO 20053986L NO 20053986 A NO20053986 A NO 20053986A NO 20053986 A NO20053986 A NO 20053986A NO 20053986 L NO20053986 L NO 20053986L
Authority
NO
Norway
Prior art keywords
polypeptides
igsf9
liv
methods
compositions
Prior art date
Application number
NO20053986A
Other languages
English (en)
Other versions
NO20053986D0 (no
Inventor
Robert J Peach
Karen Mclachlan
Scott Glaser
Tony Rowe
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of NO20053986D0 publication Critical patent/NO20053986D0/no
Publication of NO20053986L publication Critical patent/NO20053986L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

S a m m e n d r a g Humane IGSF9 og LIV- I polypeptider og DNA (RNA) som koder for slike polypeptider er redegjort for. De beskrevne polypeptidene og/eller polynukleotidene er spesielt anvendelige i å danne antistoffer, både modifiserte og native, som binder seg til IGSF9 eller LIV- l. Også redegjort for er farmasøytiske sammensetninger og vaksiner som består av antistoffene, polypeptidene og polynukleotidene tilhørende oppfinnelsen. Også redegjort for er metoder for å benytte slike polypeptider for å identifisere ligander, antagonister og agonister til nevnte polypeptider. Endelig er metodene, som omfatter de ovenfor nevnte sammensetningene redegjort for, hva gjelder behandling, diagnose, og/eller prognose av neoplastiske forstyrrelser.
NO20053986A 2003-01-27 2005-08-26 Sammensetninger og fremgangsmater for a behandle cancer anvendende IGSF9 og LIV-1. NO20053986L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44253503P 2003-01-27 2003-01-27
PCT/US2004/002044 WO2004066933A2 (en) 2003-01-27 2004-01-27 Compositions and methods for treating cancer using igsf9 and liv-1

Publications (2)

Publication Number Publication Date
NO20053986D0 NO20053986D0 (no) 2005-08-26
NO20053986L true NO20053986L (no) 2005-10-27

Family

ID=32825236

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053986A NO20053986L (no) 2003-01-27 2005-08-26 Sammensetninger og fremgangsmater for a behandle cancer anvendende IGSF9 og LIV-1.

Country Status (16)

Country Link
US (2) US20040258616A1 (no)
EP (1) EP1596806A4 (no)
JP (1) JP2006520194A (no)
KR (1) KR20050102627A (no)
CN (1) CN1849337A (no)
AU (1) AU2004207538A1 (no)
BR (1) BRPI0407031A (no)
CA (1) CA2514062A1 (no)
EA (1) EA200501197A1 (no)
IS (1) IS7960A (no)
MX (1) MXPA05007940A (no)
NO (1) NO20053986L (no)
PL (1) PL379264A1 (no)
RS (1) RS20050577A (no)
WO (1) WO2004066933A2 (no)
ZA (1) ZA200506671B (no)

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US20040141983A1 (en) 1999-03-15 2004-07-22 Protein Design Labs, Inc. Compositions against cancer antigen LIV-1 and uses thereof
WO2004067564A2 (en) 2003-01-29 2004-08-12 Protein Design Labs, Inc. Compositions against cancer antigen liv-1 and uses thereof
WO2005063301A1 (ja) * 2003-12-26 2005-07-14 Toshio Hirano Emt誘導剤
US20090214517A1 (en) * 2004-07-27 2009-08-27 Justin Wong Compositions and methods of use for modulators of nectin 4, semaphorin 4b, igsf9, and kiaa0152 in treating disease
WO2007120787A2 (en) * 2006-04-13 2007-10-25 Novartis Vaccines & Diagnostics, Inc. Methods of treating, diagnosing or detecting cancers associated with liv-1 overexpression
KR20110091423A (ko) * 2010-02-05 2011-08-11 국립암센터 항―ｔｍａｐ／ｃｋａｐ２ 항체를 포함하는 암의 예후 진단용 조성물
SG10201510041QA (en) * 2010-12-06 2016-01-28 Seattle Genetics Inc Humanized antibodies to liv-1 and use of same to treat cancer
MA45324A (fr) 2016-03-15 2019-01-23 Seattle Genetics Inc Polythérapie utilisant un adc-liv1 et un agent chimiothérapeutique
US11512114B2 (en) 2017-05-09 2022-11-29 Cyano Biotech Gmbh Modified microcystins and nodularins
CN110563845A (zh) * 2019-09-12 2019-12-13 滨州医学院 抗igsf9抗体、药物组合物及其应用
WO2021201571A1 (ko) * 2020-03-31 2021-10-07 웰마커바이오 주식회사 Igsf1 에 대한 항체를 유효성분으로 포함하는 암 예방 또는 치료용 약학 조성물 및 이를 이용한 암 치료 방법
CN116082503B (zh) * 2022-08-19 2023-08-04 滨州医学院 一种靶向人igsf9的单克隆抗体及其应用
WO2024109944A1 (zh) * 2022-11-25 2024-05-30 江苏恒瑞医药股份有限公司 抗liv-1抗体、其药物偶联物及其医药用途
CN117379561B (zh) * 2023-10-13 2025-07-22 滨州医学院 一种靶向人igsf9的抗体偶联药物及其制备方法与应用

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Also Published As

Publication number Publication date
ZA200506671B (en) 2006-09-27
EA200501197A1 (ru) 2006-04-28
JP2006520194A (ja) 2006-09-07
WO2004066933A3 (en) 2006-03-02
CN1849337A (zh) 2006-10-18
NO20053986D0 (no) 2005-08-26
RS20050577A (sr) 2007-09-21
US20040258616A1 (en) 2004-12-23
EP1596806A4 (en) 2007-08-29
AU2004207538A1 (en) 2004-08-12
BRPI0407031A (pt) 2006-01-17
WO2004066933A2 (en) 2004-08-12
KR20050102627A (ko) 2005-10-26
CA2514062A1 (en) 2004-08-12
EP1596806A2 (en) 2005-11-23
US20070071674A1 (en) 2007-03-29
MXPA05007940A (es) 2007-06-14
PL379264A1 (pl) 2006-08-07
IS7960A (is) 2005-07-27

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