NO20040768L - Fremgangsmate for rensing av glykopeptidfosfonatderivater. - Google Patents
Fremgangsmate for rensing av glykopeptidfosfonatderivater.Info
- Publication number
- NO20040768L NO20040768L NO20040768A NO20040768A NO20040768L NO 20040768 L NO20040768 L NO 20040768L NO 20040768 A NO20040768 A NO 20040768A NO 20040768 A NO20040768 A NO 20040768A NO 20040768 L NO20040768 L NO 20040768L
- Authority
- NO
- Norway
- Prior art keywords
- purification
- glycopeptide
- phosphonate derivatives
- glycopeptide phosphonate
- derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000002068 Glycopeptides Human genes 0.000 title abstract 2
- 108010015899 Glycopeptides Proteins 0.000 title abstract 2
- -1 glycopeptide phosphonate derivatives Chemical class 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- DQJCDTNMLBYVAY-ZXXIYAEKSA-N (2S,5R,10R,13R)-16-{[(2R,3S,4R,5R)-3-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-(ethylamino)-6-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-5-(4-aminobutyl)-10-carbamoyl-2,13-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazaheptadecan-1-oic acid Chemical class NCCCC[C@H](C(=O)N[C@@H](C)C(O)=O)NC(=O)CC[C@H](C(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)O[C@@H]1[C@@H](NCC)C(O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DQJCDTNMLBYVAY-ZXXIYAEKSA-N 0.000 abstract 2
- 239000011347 resin Substances 0.000 abstract 2
- 229920005989 resin Polymers 0.000 abstract 2
- 239000004793 Polystyrene Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 125000001476 phosphono group Chemical group [H]OP(*)(=O)O[H] 0.000 abstract 1
- 229920002223 polystyrene Polymers 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31471201P | 2001-08-24 | 2001-08-24 | |
| PCT/US2002/026854 WO2003018608A2 (en) | 2001-08-24 | 2002-08-23 | Process for purifying glycopeptide phosphonate derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20040768L true NO20040768L (no) | 2004-04-29 |
| NO330734B1 NO330734B1 (no) | 2011-06-27 |
Family
ID=23221118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20040768A NO330734B1 (no) | 2001-08-24 | 2004-02-20 | Fremgangsmåte for rensing av glykopeptidfosfonatderivater. |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US7015307B2 (no) |
| EP (1) | EP1487863B1 (no) |
| JP (1) | JP4116547B2 (no) |
| KR (1) | KR100905009B1 (no) |
| CN (1) | CN100418980C (no) |
| AT (1) | ATE430159T1 (no) |
| AU (1) | AU2002326740A1 (no) |
| CA (1) | CA2457218C (no) |
| DE (1) | DE60232197D1 (no) |
| DK (1) | DK1487863T3 (no) |
| ES (1) | ES2324771T3 (no) |
| NO (1) | NO330734B1 (no) |
| TW (1) | TWI233932B (no) |
| WO (1) | WO2003018608A2 (no) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA75083C2 (uk) * | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
| TWI233932B (en) * | 2001-08-24 | 2005-06-11 | Theravance Inc | Process for purifying glycopeptide phosphonate derivatives |
| TWI342312B (en) * | 2003-10-22 | 2011-05-21 | Theravance Inc | Hydrochloride salts of a glycopeptide phosphonate derivative |
| AU2005308160A1 (en) | 2004-11-29 | 2006-06-01 | National University Corporation Nagoya University | Glycopeptide antibiotic monomer derivatives |
| TW200808818A (en) * | 2006-05-26 | 2008-02-16 | Shionogi & Co | Glycopeptide antibiotic derivatives |
| US20090069219A1 (en) * | 2007-09-09 | 2009-03-12 | Protia, Llc | Deuterium-enriched telavancin |
| EP2238102A4 (en) * | 2007-12-26 | 2011-03-09 | Lead Therapeutics Inc | NEW HALF-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS |
| GB2465863A (en) * | 2008-12-05 | 2010-06-09 | Lead Therapeutics Inc | Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections |
| CN103105327A (zh) * | 2011-11-11 | 2013-05-15 | 中国科学院大连化学物理研究所 | 采用金属氧化物富集糖肽的通用方法 |
| US9753436B2 (en) | 2013-06-11 | 2017-09-05 | Apple Inc. | Rotary input mechanism for an electronic device |
| KR102231031B1 (ko) | 2013-08-09 | 2021-03-23 | 애플 인크. | 전자 디바이스용 촉각 스위치 |
| CN107759672A (zh) | 2013-08-19 | 2018-03-06 | 南京爱斯药业有限公司 | 万古霉素衍生物、制备方法及其应用 |
| US10048802B2 (en) | 2014-02-12 | 2018-08-14 | Apple Inc. | Rejection of false turns of rotary inputs for electronic devices |
| US10190891B1 (en) | 2014-07-16 | 2019-01-29 | Apple Inc. | Optical encoder for detecting rotational and axial movement |
| KR102544557B1 (ko) | 2014-09-02 | 2023-06-20 | 애플 인크. | 웨어러블 전자 디바이스 |
| WO2016137806A2 (en) | 2015-02-23 | 2016-09-01 | Theravance Biopharma Antibiotics Ip, Llc | Doses and methods of administering telavancin |
| CN105985412A (zh) * | 2015-02-28 | 2016-10-05 | 爱斯医药科技(南京)有限公司 | 万古霉素衍生物、制备方法及其应用 |
| JP6515185B2 (ja) | 2015-03-05 | 2019-05-15 | アップル インコーポレイテッドApple Inc. | 方向依存光学特性を有する光学エンコーダを有する時計、手首装着型電子デバイス及びウェラブル電子デバイス |
| WO2016144919A1 (en) | 2015-03-08 | 2016-09-15 | Apple Inc. | Compressible seal for rotatable and translatable input mechanisms |
| US10018966B2 (en) | 2015-04-24 | 2018-07-10 | Apple Inc. | Cover member for an input mechanism of an electronic device |
| US9891651B2 (en) | 2016-02-27 | 2018-02-13 | Apple Inc. | Rotatable input mechanism having adjustable output |
| CN107325159A (zh) * | 2016-04-29 | 2017-11-07 | 中国科学院上海药物研究所 | 一类万古霉素衍生物、其制备方法、药物组合物和用途 |
| US10551798B1 (en) | 2016-05-17 | 2020-02-04 | Apple Inc. | Rotatable crown for an electronic device |
| US10061399B2 (en) | 2016-07-15 | 2018-08-28 | Apple Inc. | Capacitive gap sensor ring for an input device |
| US10019097B2 (en) | 2016-07-25 | 2018-07-10 | Apple Inc. | Force-detecting input structure |
| US10664074B2 (en) | 2017-06-19 | 2020-05-26 | Apple Inc. | Contact-sensitive crown for an electronic watch |
| US10962935B1 (en) | 2017-07-18 | 2021-03-30 | Apple Inc. | Tri-axis force sensor |
| US11360440B2 (en) | 2018-06-25 | 2022-06-14 | Apple Inc. | Crown for an electronic watch |
| US11561515B2 (en) | 2018-08-02 | 2023-01-24 | Apple Inc. | Crown for an electronic watch |
| US12259690B2 (en) | 2018-08-24 | 2025-03-25 | Apple Inc. | Watch crown having a conductive surface |
| CN209560398U (zh) | 2018-08-24 | 2019-10-29 | 苹果公司 | 电子表 |
| US11181863B2 (en) | 2018-08-24 | 2021-11-23 | Apple Inc. | Conductive cap for watch crown |
| US11194298B2 (en) | 2018-08-30 | 2021-12-07 | Apple Inc. | Crown assembly for an electronic watch |
| CN209625187U (zh) | 2018-08-30 | 2019-11-12 | 苹果公司 | 电子手表和电子设备 |
| US11194299B1 (en) | 2019-02-12 | 2021-12-07 | Apple Inc. | Variable frictional feedback device for a digital crown of an electronic watch |
| US11550268B2 (en) | 2020-06-02 | 2023-01-10 | Apple Inc. | Switch module for electronic crown assembly |
| US11635786B2 (en) | 2020-06-11 | 2023-04-25 | Apple Inc. | Electronic optical sensing device |
| US12092996B2 (en) | 2021-07-16 | 2024-09-17 | Apple Inc. | Laser-based rotation sensor for a crown of an electronic watch |
| US12189347B2 (en) | 2022-06-14 | 2025-01-07 | Apple Inc. | Rotation sensor for a crown of an electronic watch |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4440753A (en) * | 1982-03-15 | 1984-04-03 | Eli Lilly And Company | Purification of glycopeptide antibiotics using non-functional resins |
| US4667024A (en) * | 1983-07-13 | 1987-05-19 | Smithkline Beckman Corporation | Process for the preparation of purified vancomycin class antibiotics |
| GB8608798D0 (en) * | 1986-04-11 | 1986-05-14 | Lepetit Spa | Recovery of glycopeptide antibiotics from aqueous solutions |
| US4845104A (en) * | 1986-11-20 | 1989-07-04 | Merck & Co., Inc. | Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones |
| US4845194A (en) * | 1987-02-27 | 1989-07-04 | Eli Lilly And Company | Glycopeptide recovery process |
| US4874843A (en) * | 1987-12-03 | 1989-10-17 | Eli Lilly And Company | Chromatographic purification process |
| US4996148A (en) * | 1987-07-13 | 1991-02-26 | Eli Lilly And Company | A80407 antibiotics |
| JP2577133B2 (ja) | 1989-11-27 | 1997-01-29 | スティフティング フォール ド テフニスヘ ウェッテンスハッペン | 船舶のプロペラ |
| US5258495A (en) * | 1990-07-10 | 1993-11-02 | Abbott Laboratories | Process for making vancomycin HC1 |
| US5149784A (en) * | 1990-07-10 | 1992-09-22 | Abbott Laboratories | Process for making vancomycin |
| DE4039451A1 (de) * | 1990-12-11 | 1992-06-17 | Hoechst Ag | Metallocene mit bicyclischen cyclopentadienderivaten als liganden, verfahren zu ihrer herstellung und ihre verwendung als katalysatoren |
| AU670081B2 (en) | 1992-04-20 | 1996-07-04 | Abbott Laboratories | Process for making vancomycin |
| AU703106B2 (en) * | 1994-01-28 | 1999-03-18 | Eli Lilly And Company | Glycopeptide antibiotic derivatives |
| SI9500039B (sl) * | 1995-02-07 | 2002-02-28 | Lek, | Nov kombiniran postopek čiščenja Vankomicin hidroklorida |
| WO1998026085A1 (fr) | 1996-12-11 | 1998-06-18 | Nippon Kayaku Kabushiki Kaisha | Procedes de fabrication de vancomycine |
| UA75083C2 (uk) | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
| TWI233932B (en) * | 2001-08-24 | 2005-06-11 | Theravance Inc | Process for purifying glycopeptide phosphonate derivatives |
-
2002
- 2002-08-20 TW TW091118800A patent/TWI233932B/zh not_active IP Right Cessation
- 2002-08-23 CN CNB028166159A patent/CN100418980C/zh not_active Expired - Fee Related
- 2002-08-23 ES ES02761476T patent/ES2324771T3/es not_active Expired - Lifetime
- 2002-08-23 EP EP02761476A patent/EP1487863B1/en not_active Expired - Lifetime
- 2002-08-23 JP JP2003523267A patent/JP4116547B2/ja not_active Expired - Fee Related
- 2002-08-23 WO PCT/US2002/026854 patent/WO2003018608A2/en not_active Ceased
- 2002-08-23 AT AT02761476T patent/ATE430159T1/de not_active IP Right Cessation
- 2002-08-23 DK DK02761476T patent/DK1487863T3/da active
- 2002-08-23 US US10/226,676 patent/US7015307B2/en not_active Expired - Lifetime
- 2002-08-23 CA CA2457218A patent/CA2457218C/en not_active Expired - Fee Related
- 2002-08-23 AU AU2002326740A patent/AU2002326740A1/en not_active Abandoned
- 2002-08-23 KR KR1020047002618A patent/KR100905009B1/ko not_active Expired - Fee Related
- 2002-08-23 DE DE60232197T patent/DE60232197D1/de not_active Expired - Lifetime
-
2004
- 2004-02-20 NO NO20040768A patent/NO330734B1/no not_active IP Right Cessation
-
2005
- 2005-12-13 US US11/301,740 patent/US7375181B2/en not_active Expired - Lifetime
-
2007
- 2007-10-25 US US11/977,605 patent/US7468420B2/en not_active Expired - Lifetime
-
2008
- 2008-11-17 US US12/272,554 patent/US7858583B2/en not_active Expired - Fee Related
-
2010
- 2010-11-16 US US12/947,686 patent/US20110257364A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NO330734B1 (no) | 2011-06-27 |
| CA2457218C (en) | 2011-08-02 |
| EP1487863B1 (en) | 2009-04-29 |
| JP4116547B2 (ja) | 2008-07-09 |
| DK1487863T3 (da) | 2009-07-13 |
| US20060100415A1 (en) | 2006-05-11 |
| EP1487863A4 (en) | 2007-08-29 |
| DE60232197D1 (de) | 2009-06-10 |
| WO2003018608A3 (en) | 2004-10-07 |
| US7375181B2 (en) | 2008-05-20 |
| WO2003018608A8 (en) | 2003-04-24 |
| CN1671732A (zh) | 2005-09-21 |
| US7858583B2 (en) | 2010-12-28 |
| TWI233932B (en) | 2005-06-11 |
| US7015307B2 (en) | 2006-03-21 |
| US20090215673A1 (en) | 2009-08-27 |
| ES2324771T3 (es) | 2009-08-14 |
| JP2005505542A (ja) | 2005-02-24 |
| CN100418980C (zh) | 2008-09-17 |
| US20080103290A1 (en) | 2008-05-01 |
| US20110257364A1 (en) | 2011-10-20 |
| WO2003018608A2 (en) | 2003-03-06 |
| CA2457218A1 (en) | 2003-03-06 |
| KR20040028998A (ko) | 2004-04-03 |
| US7468420B2 (en) | 2008-12-23 |
| EP1487863A2 (en) | 2004-12-22 |
| KR100905009B1 (ko) | 2009-06-29 |
| AU2002326740A1 (en) | 2003-03-10 |
| US20030119722A1 (en) | 2003-06-26 |
| ATE430159T1 (de) | 2009-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: THERAVANCE BIOPHARMA R&D IP, US |
|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: THERAVANCE BIOPHARMA ANTIBIOTICS IP, US |
|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: CUMBERLAND PHARMACEUTICALS INC., US |
|
| MM1K | Lapsed by not paying the annual fees |