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NO20032830D0 - Tetrahydropyridinderivater, fremstilling derav og anvendelse som celle-proliferasjonsinhibitorer - Google Patents

Tetrahydropyridinderivater, fremstilling derav og anvendelse som celle-proliferasjonsinhibitorer

Info

Publication number
NO20032830D0
NO20032830D0 NO20032830A NO20032830A NO20032830D0 NO 20032830 D0 NO20032830 D0 NO 20032830D0 NO 20032830 A NO20032830 A NO 20032830A NO 20032830 A NO20032830 A NO 20032830A NO 20032830 D0 NO20032830 D0 NO 20032830D0
Authority
NO
Norway
Prior art keywords
preparation
cell proliferation
proliferation inhibitors
tetrahydropyridine derivatives
tetrahydropyridine
Prior art date
Application number
NO20032830A
Other languages
English (en)
Other versions
NO20032830L (no
Inventor
Guy Georges
Adelbert Grossmann
Olaf Mundigl
Wolfgang Von Der Saal
Tim Sattelkau
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20032830D0 publication Critical patent/NO20032830D0/no
Publication of NO20032830L publication Critical patent/NO20032830L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO20032830A 2000-12-23 2003-06-20 Tetrahydropyridinderivater, fremstilling derav og anvendelse som celleproliferasjonsinhibitorer NO20032830L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00128487 2000-12-23
PCT/EP2001/015390 WO2002051842A1 (en) 2000-12-23 2001-12-21 Tetrahydropyridine derivatives, their preparation and their use as cell proliferation inhibitors

Publications (2)

Publication Number Publication Date
NO20032830D0 true NO20032830D0 (no) 2003-06-20
NO20032830L NO20032830L (no) 2003-08-04

Family

ID=8170814

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20032830A NO20032830L (no) 2000-12-23 2003-06-20 Tetrahydropyridinderivater, fremstilling derav og anvendelse som celleproliferasjonsinhibitorer

Country Status (27)

Country Link
US (1) US6800638B2 (no)
EP (1) EP1353921B1 (no)
JP (1) JP2004516325A (no)
KR (1) KR100836545B1 (no)
CN (1) CN1213046C (no)
AR (1) AR035513A1 (no)
AT (1) ATE323700T1 (no)
AU (1) AU2002226397B2 (no)
BG (1) BG107935A (no)
BR (1) BR0116402A (no)
CA (1) CA2431471A1 (no)
CZ (1) CZ20031940A3 (no)
DE (1) DE60118975T2 (no)
EC (1) ECSP034664A (no)
ES (1) ES2261519T3 (no)
HU (1) HUP0400554A2 (no)
IL (1) IL156131A0 (no)
MA (1) MA26976A1 (no)
MX (1) MXPA03005713A (no)
NO (1) NO20032830L (no)
NZ (1) NZ526189A (no)
PL (1) PL365531A1 (no)
RU (1) RU2276140C2 (no)
SK (1) SK9122003A3 (no)
WO (1) WO2002051842A1 (no)
YU (1) YU48803A (no)
ZA (1) ZA200304264B (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706686B2 (en) 2001-09-27 2004-03-16 The Regents Of The University Of Colorado Inhibition of histone deacetylase as a treatment for cardiac hypertrophy
EP1443928B1 (en) 2001-10-16 2011-07-27 Sloan-Kettering Institute For Cancer Research Treatment of neurodegenerative diseases and cancer of the brain
WO2003083323A1 (en) 2002-04-01 2003-10-09 Ranko Rakanovic Rubber elastic element
US7154002B1 (en) 2002-10-08 2006-12-26 Takeda San Diego, Inc. Histone deacetylase inhibitors
US7250514B1 (en) 2002-10-21 2007-07-31 Takeda San Diego, Inc. Histone deacetylase inhibitors
AU2003900608A0 (en) * 2003-02-11 2003-02-27 Fujisawa Pharmaceutical Co., Ltd. Hdac inhibitor
US7169801B2 (en) 2003-03-17 2007-01-30 Takeda San Diego, Inc. Histone deacetylase inhibitors
US20060235012A1 (en) * 2003-06-16 2006-10-19 Chroma Therapeutics Limited Carboline and betacarboline derivatives for use as hdac enzyme inhibitors
EP1694329A4 (en) * 2003-11-26 2009-06-03 Aton Pharma Inc DIAMOND AND IMINODIACETIC ACID HYDROXAMINIC DERIVATIVES
US20050159470A1 (en) * 2003-12-19 2005-07-21 Syrrx, Inc. Histone deacetylase inhibitors
WO2005066151A2 (en) * 2003-12-19 2005-07-21 Takeda San Diego, Inc. Histone deacetylase inhibitors
WO2006066133A2 (en) * 2004-12-16 2006-06-22 Takeda San Diego, Inc. Histone deacetylase inhibitors
CA2596015A1 (en) 2005-02-14 2006-08-24 Sampath K. Anandan Fused heterocyclic compounds useful as inhibitors of histone deacetylase
GB0509223D0 (en) * 2005-05-05 2005-06-15 Chroma Therapeutics Ltd Enzyme inhibitors
US7642253B2 (en) 2005-05-11 2010-01-05 Takeda San Diego, Inc. Histone deacetylase inhibitors
WO2007011626A2 (en) * 2005-07-14 2007-01-25 Takeda San Diego, Inc. Histone deacetylase inhibitors
EP1928437A2 (en) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
JP2009525955A (ja) * 2006-01-13 2009-07-16 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼ阻害剤
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
TWI425945B (zh) * 2007-05-28 2014-02-11 Seldar Pharma Inc 四氫異喹啉－１－酮衍生物或其鹽
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CA2768466C (en) * 2009-07-22 2018-08-14 The Board Of Trustees Of The University Of Illinois Hdac inhibitors and therapeutic methods using the same
CN102153549B (zh) * 2010-12-14 2012-11-14 华东理工大学 γ咔啉化合物、制备方法和用途
NZ712696A (en) 2013-04-29 2016-07-29 Chong Kun Dang Pharm Corp Novel compounds for selective histone deacetylase inhibitors, and pharmaceutical composition comprising the same
EP3052662B1 (en) 2013-10-01 2019-05-15 The J. David Gladstone Institutes Compositions, systems and methods for gene expression noise drug screening and uses thereof
CN108084178B (zh) * 2018-01-04 2020-09-01 济南大学 一类含有四氢-β-咔碄结构的异羟肟酸类化合物的用途
CN108558653A (zh) * 2018-05-14 2018-09-21 湖南华腾制药有限公司 赛乐西帕中间体及赛乐西帕的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196758B (en) * 1986-05-21 1989-01-30 Gyogyszerkutato Intezet Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them
WO1990002119A1 (fr) * 1988-08-18 1990-03-08 Banyu Pharmaceutical Co., Ltd. Derives de 1,2,3,4-tetrahydro-isoquinoline
US5369108A (en) * 1991-10-04 1994-11-29 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
US6429212B1 (en) * 1996-08-16 2002-08-06 Ishihara Sangyo Kaisha Ltd. Medicinal composition
WO1998015525A1 (en) * 1996-10-07 1998-04-16 Sumitomo Pharmaceuticals Co., Ltd. Hydroxamic acids
AUPO721997A0 (en) * 1997-06-06 1997-07-03 Queensland Institute Of Medical Research, The Anticancer compounds
AU3312100A (en) * 1999-03-22 2000-10-09 Darwin Discovery Limited Hydroxamic and carboxylic acid derivatives

Also Published As

Publication number Publication date
CZ20031940A3 (cs) 2003-10-15
ES2261519T3 (es) 2006-11-16
US20040053960A1 (en) 2004-03-18
PL365531A1 (en) 2005-01-10
EP1353921B1 (en) 2006-04-19
NO20032830L (no) 2003-08-04
DE60118975T2 (de) 2006-12-21
WO2002051842A1 (en) 2002-07-04
NZ526189A (en) 2004-10-29
IL156131A0 (en) 2003-12-23
KR100836545B1 (ko) 2008-06-10
MA26976A1 (fr) 2004-12-20
ATE323700T1 (de) 2006-05-15
BR0116402A (pt) 2003-11-11
SK9122003A3 (en) 2004-02-03
RU2276140C2 (ru) 2006-05-10
YU48803A (sh) 2006-05-25
EP1353921A1 (en) 2003-10-22
MXPA03005713A (es) 2003-10-06
HUP0400554A2 (hu) 2004-06-28
JP2004516325A (ja) 2004-06-03
DE60118975D1 (de) 2006-05-24
KR20030063424A (ko) 2003-07-28
US6800638B2 (en) 2004-10-05
CN1483033A (zh) 2004-03-17
CA2431471A1 (en) 2002-07-04
BG107935A (bg) 2004-08-31
CN1213046C (zh) 2005-08-03
RU2003122190A (ru) 2005-02-27
ECSP034664A (es) 2003-07-25
AR035513A1 (es) 2004-06-02
ZA200304264B (en) 2004-08-30
AU2002226397B2 (en) 2006-10-05

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