NO20025601D0 - Arylmetylaminderivater for anvendelse som tryptaseinhibitorer - Google Patents
Arylmetylaminderivater for anvendelse som tryptaseinhibitorerInfo
- Publication number
- NO20025601D0 NO20025601D0 NO20025601A NO20025601A NO20025601D0 NO 20025601 D0 NO20025601 D0 NO 20025601D0 NO 20025601 A NO20025601 A NO 20025601A NO 20025601 A NO20025601 A NO 20025601A NO 20025601 D0 NO20025601 D0 NO 20025601D0
- Authority
- NO
- Norway
- Prior art keywords
- tryptase
- tryptase inhibitors
- arylmethylamine
- derivatives
- arylmethylamine derivatives
- Prior art date
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- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- Organic Chemistry (AREA)
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- Life Sciences & Earth Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0012362.0A GB0012362D0 (en) | 2000-05-22 | 2000-05-22 | Chemical compounds |
| US09/843,126 US6977263B2 (en) | 2000-05-22 | 2001-04-26 | Chemical compounds |
| PCT/US2001/013811 WO2001090101A1 (en) | 2000-05-22 | 2001-04-27 | Arylmethylamine derivatives for use as tryptase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20025601D0 true NO20025601D0 (no) | 2002-11-21 |
| NO20025601L NO20025601L (no) | 2003-01-06 |
| NO327378B1 NO327378B1 (no) | 2009-06-22 |
Family
ID=26244322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20025601A NO327378B1 (no) | 2000-05-22 | 2002-11-21 | Arylmetylaminderivater, anvendelse av forbindelsene samt farmasoytiske sammensetninger. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20050228018A1 (no) |
| EP (1) | EP1296972B1 (no) |
| KR (1) | KR100858642B1 (no) |
| CN (1) | CN1230431C (no) |
| AR (1) | AR033525A1 (no) |
| AU (2) | AU2001257413B2 (no) |
| BR (1) | BR0111206A (no) |
| CA (1) | CA2409827C (no) |
| DZ (1) | DZ3347A1 (no) |
| HR (1) | HRP20020926B1 (no) |
| HU (1) | HU227630B1 (no) |
| IL (1) | IL152830A0 (no) |
| MA (1) | MA25809A1 (no) |
| MX (1) | MXPA02011400A (no) |
| NO (1) | NO327378B1 (no) |
| OA (1) | OA12274A (no) |
| PL (1) | PL360495A1 (no) |
| WO (1) | WO2001090101A1 (no) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7662826B2 (en) | 2002-04-23 | 2010-02-16 | Shionogi & Co., Ltd. | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same |
| EA008928B1 (ru) | 2002-11-26 | 2007-08-31 | Пфайзер Продактс Инк. | Активаторы рецепторов, активируемых пролифератором пероксисом (ppar ) |
| GB0308613D0 (en) * | 2002-12-26 | 2003-05-21 | Aventis Pharma Inc | 4-(3-Aminomethylphenyl) piperidin-1-yl- 5-(2-fluorophenylethynyl) furan-2-yl- methanone as an inhibitor of mast cell tryptase |
| ES2887054T3 (es) | 2003-04-11 | 2021-12-21 | Ptc Therapeutics Inc | Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades |
| EP1620405A2 (en) * | 2003-05-01 | 2006-02-01 | Abbott Laboratories | Pyrazole-amides and sulfonamides as sodium channel modulators |
| SI1867644T1 (sl) | 2003-07-24 | 2009-10-31 | Euro Celtique Sa | Heteroaril-tetrahidropiperidilne spojine, koristne za zdravljenje ali preprečevanje bolečine |
| EP1571150A1 (en) * | 2004-03-02 | 2005-09-07 | Aventis Pharma Deutschland GmbH | Process for the preparation of tryptase inhibitors |
| HRP20100040T1 (hr) * | 2004-03-02 | 2010-02-28 | Aventis Pharmaceuticals Inc. | Postupak dobivanja inhibitora triptaze |
| EP1729771B1 (en) * | 2004-03-22 | 2009-10-14 | Eli Lilly & Company | Pyridyl derivatives and their use as mglu5 receptor antagonists |
| DOP2005000039A (es) * | 2004-03-26 | 2005-10-31 | Aventis Pharma Inc | Hidrocloruro de [4-(5-aminometil-2-fluoro-fenil)- piperidin-1-il]-(4-bomo-3-metil-5-propoxi-tiofen-2-il)-metanona como un inhibidor de la triptasa de mastocitos |
| CN102827082B (zh) | 2004-07-01 | 2015-01-07 | 第一三共株式会社 | 具有pde7抑制活性的噻吩并吡唑衍生物 |
| WO2006014012A2 (en) | 2004-08-06 | 2006-02-09 | Otsuka Pharmaceutical Co., Ltd. | Aromatic compounds |
| WO2006044456A1 (en) * | 2004-10-13 | 2006-04-27 | Ptc Therapeutics, Inc. | Compounds for nonsense suppression, and methods for their use |
| US7880007B2 (en) | 2004-11-29 | 2011-02-01 | Vertex Pharmaceuticals Incorporated | Bicyclic substituted phenyl piperidine modulators of muscarinic receptors |
| WO2006066879A2 (en) * | 2004-12-21 | 2006-06-29 | Devgen N.V. | Compounds with kv4 ion channel activity |
| US7576218B2 (en) * | 2005-10-11 | 2009-08-18 | Chemocentryx, Inc. | 4-phenylpiperdine-pyrazole CCR1 antagonists |
| AU2006323700B2 (en) | 2005-12-05 | 2011-02-17 | Otsuka Pharmaceutical Co., Ltd. | Diarylether derivatives as antitumor agents |
| IN2014CN04406A (no) | 2006-03-30 | 2015-09-04 | Ptc Therapeutics Inc | |
| WO2008019302A1 (en) * | 2006-08-04 | 2008-02-14 | Decode Genetics Ehf | Pyrazolylphenyl and pyrrolylphenyl inhibitors of lta4h for treating inflammation |
| UA95978C2 (ru) | 2006-10-02 | 2011-09-26 | Оцука Фармас'Ютікел Ко., Лтд. | Ингибитор активации stat3/5 |
| TW200833663A (en) * | 2006-12-21 | 2008-08-16 | Astrazeneca Ab | Therapeutic agents |
| WO2008075077A1 (en) * | 2006-12-21 | 2008-06-26 | Astrazeneca Ab | Piperidine derivatives for the treatment of obesity |
| JP5603770B2 (ja) | 2007-05-31 | 2014-10-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ccr2受容体拮抗薬およびその使用 |
| WO2009044403A2 (en) * | 2007-10-05 | 2009-04-09 | Juvenis Ltd. | Injectable biodegradable polymer compositions for soft tissue repair and augmentation |
| JP2011504499A (ja) | 2007-11-21 | 2011-02-10 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | トリプターゼ阻害剤として使用するためのスピロピペリジン |
| PL2234485T3 (pl) * | 2007-12-20 | 2014-06-30 | Teva Pharma | Stabilne preparaty lakwinimodu |
| HRP20151338T1 (hr) * | 2008-08-22 | 2016-01-15 | Sanofi | [4-(5-aminometil-2-fluoro-fenil)-piperidin-1-il]-[7-fluoro-1-(2-metoksi-etil)-4trifluorometoksi-1h-indol-3-il]metanon kao inhibitor triptaze mastocita |
| EA020548B1 (ru) | 2008-12-19 | 2014-12-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Циклические пиримидин-4-карбоксамиды в качестве антагонистов рецептора ccr2, предназначенные для лечения воспаления, астмы и хозл |
| FR2955324A1 (fr) * | 2010-01-15 | 2011-07-22 | Sanofi Aventis | [4-(5-aminomethyl-phenyl)-piperidin-1-yl]-1h-indol-3-yl]-methanones disubstituees |
| PE20121614A1 (es) | 2009-12-17 | 2012-12-21 | Boehringer Ingelheim Int | Derivados de 6-amino,4-carbonil-pirimidina sustituida como antagonistas del receptor ccr2 |
| MX2012006741A (es) * | 2009-12-23 | 2012-07-04 | Sanofi Sa | Tratamiento para la enfermedad inflamatoria del intestino. |
| EP2519520A1 (en) * | 2009-12-23 | 2012-11-07 | Sanofi | [4-(3-aminomethyl-phenyl)-piperidin-1-yl]-(1h-pyrrolopyridinyl)-methanone derivatives as tryptase inhibitors |
| PT2516418E (pt) * | 2009-12-23 | 2014-07-18 | Sanofi Sa | Profármacos de [4[4-(5-aminometil-2-fluoro-fenil)-piperidin-1- il]-(1h-pirrolo-piridin-il)-metanonas e sua síntese |
| RU2012131341A (ru) * | 2009-12-23 | 2014-01-27 | Санофи | Индол-пиперидинилбензиламины как ингибиторы бета-триптазы |
| WO2011079103A1 (en) * | 2009-12-23 | 2011-06-30 | Sanofi | Spiropiperidine benzylamines as beta-tryptase inhibitors |
| ES2703176T3 (es) * | 2010-03-11 | 2019-03-07 | Univ New York | Compuestos amido como moduladores de RORgammat y usos de los mismos |
| EP2569298B1 (en) | 2010-05-12 | 2015-11-25 | Boehringer Ingelheim International GmbH | Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments |
| JP5646736B2 (ja) | 2010-05-12 | 2014-12-24 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規ccr2受容体アンタゴニスト、これらの製造方法、及び薬物としてのこれらの使用 |
| WO2011144501A1 (en) | 2010-05-17 | 2011-11-24 | Boehringer Ingelheim International Gmbh | Ccr2 antagonists and uses thereof |
| WO2011147772A1 (en) | 2010-05-25 | 2011-12-01 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists |
| EP2576538B1 (en) | 2010-06-01 | 2015-10-28 | Boehringer Ingelheim International GmbH | New CCR2 antagonists |
| JP2014512364A (ja) | 2011-04-07 | 2014-05-22 | コーネル ユニバーシティー | 水溶液中で二量体化できる単量体、およびその使用法 |
| JP5786258B2 (ja) | 2011-07-15 | 2015-09-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規かつ選択的なccr2拮抗薬 |
| US10092574B2 (en) | 2012-09-26 | 2018-10-09 | Valorisation-Recherche, Limited Partnership | Inhibitors of polynucleotide repeat-associated RNA foci and uses thereof |
| JP6203194B2 (ja) | 2012-11-30 | 2017-09-27 | 協和発酵キリン株式会社 | 含窒素複素環化合物 |
| TW201441193A (zh) | 2012-12-06 | 2014-11-01 | Kyowa Hakko Kirin Co Ltd | 吡啶酮化合物 |
| WO2015073864A1 (en) | 2013-11-15 | 2015-05-21 | The Wisar Institute Of Anatomy And Biology | Ebna1 inhibitors and their method of use |
| WO2015134711A1 (en) | 2014-03-06 | 2015-09-11 | Ptc Therapeutics, Inc. | Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid |
| BR112017024481B1 (pt) | 2015-05-14 | 2020-11-17 | The Wistar Institute Of Anatomy And Biology | composto inibidor de ebna1, composição farmacêutica compreendendo dito composto e usos terapêuticos do mesmo |
| CA2990460C (en) | 2015-07-02 | 2023-10-17 | Centrexion Therapeutics Corporation | (4-((3r,4r)-3-methoxytetrahydro-pyran-4-ylamino)piperidin-1-yl)(5-methyl-6-(((2r,6s)-6-(p-tolyl)tetrahydro-2h-pyran-2-yl)methylamino)pyrimidin-4-yl)methanone citrate |
| CN108348527A (zh) | 2015-10-30 | 2018-07-31 | Ptc医疗公司 | 用于治疗癫痫的方法 |
| CN112543634A (zh) | 2018-05-17 | 2021-03-23 | 威斯达研究所 | Ebna1抑制剂晶体形式及其制备和使用方法 |
| US12479816B2 (en) | 2019-02-08 | 2025-11-25 | University of Pittsburgh—of the Commonwealth System of Higher Education | 20-HETE formation inhibitors |
| CN110357833B (zh) * | 2019-06-03 | 2022-05-24 | 杭州维坦医药科技有限公司 | 芳杂乙酰胺类衍生物及其制备和应用 |
| TW202115086A (zh) | 2019-06-28 | 2021-04-16 | 美商輝瑞大藥廠 | Bckdk抑制劑 |
| MX2022015253A (es) * | 2020-06-04 | 2023-03-14 | Pillai Universal Llc | Moleculas peque?as novedosas para la degradacion dirigida de kras no dirigibles en la terapia contra el cancer. |
| WO2025195508A1 (zh) * | 2024-03-22 | 2025-09-25 | 润尔眼科药物(广州)有限公司 | 一种苯基杂环化合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4407139A1 (de) * | 1994-03-04 | 1995-09-07 | Thomae Gmbh Dr K | Aryl-1-azacycloalkane und deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| US6673908B1 (en) * | 1999-02-22 | 2004-01-06 | Nuvelo, Inc. | Tumor necrosis factor receptor 2 |
-
2001
- 2001-04-27 AR ARP010102009A patent/AR033525A1/es active IP Right Grant
- 2001-04-27 CN CNB018119522A patent/CN1230431C/zh not_active Expired - Lifetime
- 2001-04-27 BR BR0111206-6A patent/BR0111206A/pt not_active IP Right Cessation
- 2001-04-27 AU AU2001257413A patent/AU2001257413B2/en not_active Ceased
- 2001-04-27 AU AU5741301A patent/AU5741301A/xx active Pending
- 2001-04-27 PL PL36049501A patent/PL360495A1/xx not_active Application Discontinuation
- 2001-04-27 HR HR20020926A patent/HRP20020926B1/xx not_active IP Right Cessation
- 2001-04-27 CA CA2409827A patent/CA2409827C/en not_active Expired - Lifetime
- 2001-04-27 IL IL15283001A patent/IL152830A0/xx unknown
- 2001-04-27 OA OA1200200357A patent/OA12274A/en unknown
- 2001-04-27 HU HU0302485A patent/HU227630B1/hu not_active IP Right Cessation
- 2001-04-27 DZ DZ013347A patent/DZ3347A1/fr active
- 2001-04-27 KR KR1020027015683A patent/KR100858642B1/ko not_active Expired - Fee Related
- 2001-04-27 EP EP01930925A patent/EP1296972B1/en not_active Expired - Lifetime
- 2001-04-27 WO PCT/US2001/013811 patent/WO2001090101A1/en not_active Ceased
- 2001-04-27 MX MXPA02011400A patent/MXPA02011400A/es active IP Right Grant
-
2002
- 2002-11-21 MA MA26919A patent/MA25809A1/fr unknown
- 2002-11-21 NO NO20025601A patent/NO327378B1/no not_active IP Right Cessation
-
2005
- 2005-02-14 US US11/057,809 patent/US20050228018A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001257413B2 (en) | 2007-01-18 |
| IL152830A0 (en) | 2003-06-24 |
| CA2409827A1 (en) | 2001-11-29 |
| NO327378B1 (no) | 2009-06-22 |
| HRP20020926A2 (en) | 2005-02-28 |
| CN1230431C (zh) | 2005-12-07 |
| AU5741301A (en) | 2001-12-03 |
| WO2001090101A1 (en) | 2001-11-29 |
| EP1296972A1 (en) | 2003-04-02 |
| AR033525A1 (es) | 2003-12-26 |
| CA2409827C (en) | 2010-06-01 |
| EP1296972B1 (en) | 2009-12-23 |
| KR100858642B1 (ko) | 2008-09-17 |
| BR0111206A (pt) | 2003-04-15 |
| DZ3347A1 (fr) | 2001-11-29 |
| KR20030003294A (ko) | 2003-01-09 |
| HRP20020926B1 (en) | 2011-01-31 |
| CN1439003A (zh) | 2003-08-27 |
| HUP0302485A3 (en) | 2007-09-28 |
| HU227630B1 (hu) | 2011-10-28 |
| HUP0302485A2 (hu) | 2003-12-29 |
| OA12274A (en) | 2006-05-09 |
| NO20025601L (no) | 2003-01-06 |
| MA25809A1 (fr) | 2003-07-01 |
| US20050228018A1 (en) | 2005-10-13 |
| PL360495A1 (en) | 2004-09-06 |
| MXPA02011400A (es) | 2003-05-23 |
| HK1057899A1 (en) | 2004-04-23 |
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| MM1K | Lapsed by not paying the annual fees |