NO20023424D0 - Corticotropin-frigjörende faktor antagonister - Google Patents
Corticotropin-frigjörende faktor antagonisterInfo
- Publication number
- NO20023424D0 NO20023424D0 NO20023424A NO20023424A NO20023424D0 NO 20023424 D0 NO20023424 D0 NO 20023424D0 NO 20023424 A NO20023424 A NO 20023424A NO 20023424 A NO20023424 A NO 20023424A NO 20023424 D0 NO20023424 D0 NO 20023424D0
- Authority
- NO
- Norway
- Prior art keywords
- corticotropin
- releasing factor
- factor antagonists
- antagonists
- releasing
- Prior art date
Links
- 229940122010 Corticotropin releasing factor antagonist Drugs 0.000 title 1
- 239000002769 corticotropin releasing factor antagonist Substances 0.000 title 1
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C07D213/643—2-Phenoxypyridines; Derivatives thereof
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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Applications Claiming Priority (2)
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| US17661100P | 2000-01-18 | 2000-01-18 | |
| PCT/IB2001/000004 WO2001053263A1 (en) | 2000-01-18 | 2001-01-05 | Corticotropin releasing factor antagonists |
Publications (2)
| Publication Number | Publication Date |
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| NO20023424D0 true NO20023424D0 (no) | 2002-07-17 |
| NO20023424L NO20023424L (no) | 2002-09-10 |
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| NO20023424A NO20023424L (no) | 2000-01-18 | 2002-07-17 | Kortikotropin-frigjörende faktorantagonister |
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| EP (1) | EP1263732A1 (no) |
| JP (1) | JP2003520272A (no) |
| KR (1) | KR20020063934A (no) |
| CN (1) | CN1395566A (no) |
| AP (1) | AP2002002583A0 (no) |
| AR (1) | AR027221A1 (no) |
| AU (1) | AU779995B2 (no) |
| BG (1) | BG106853A (no) |
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| CO (1) | CO5271658A1 (no) |
| CR (1) | CR6698A (no) |
| CZ (1) | CZ20022390A3 (no) |
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| GT (1) | GT200100007A (no) |
| HN (1) | HN2001000006A (no) |
| HR (1) | HRP20020599A2 (no) |
| HU (1) | HUP0204272A3 (no) |
| IL (1) | IL150632A0 (no) |
| IS (1) | IS6445A (no) |
| MA (1) | MA26864A1 (no) |
| MX (1) | MXPA02007047A (no) |
| NO (1) | NO20023424L (no) |
| OA (1) | OA12157A (no) |
| PA (1) | PA8510001A1 (no) |
| PE (1) | PE20011166A1 (no) |
| PL (1) | PL357589A1 (no) |
| SK (1) | SK10062002A3 (no) |
| SV (1) | SV2002000289A (no) |
| TN (1) | TNSN01008A1 (no) |
| UY (1) | UY26544A1 (no) |
| WO (1) | WO2001053263A1 (no) |
| YU (1) | YU54402A (no) |
| ZA (1) | ZA200205660B (no) |
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| US6956047B1 (en) * | 1995-06-06 | 2005-10-18 | Pfizer Inc. | Corticotropin releasing factor antagonists |
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| GB0117396D0 (en) | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
| US7323469B2 (en) | 2001-08-07 | 2008-01-29 | Novartis Ag | 7H-pyrrolo[2,3-d]pyrimidine derivatives |
| GB0119249D0 (en) | 2001-08-07 | 2001-10-03 | Novartis Ag | Organic compounds |
| TW200409629A (en) | 2002-06-27 | 2004-06-16 | Bristol Myers Squibb Co | 2,4-disubstituted-pyridine N-oxides useful as HIV reverse transcriptase inhibitors |
| EP1688408A3 (en) * | 2002-08-08 | 2007-08-22 | Amgen, Inc | Vanilloid receptor ligands and their use in treatments |
| EP1546116A1 (en) * | 2002-08-08 | 2005-06-29 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| ES2295816T3 (es) | 2003-01-14 | 2008-04-16 | Arena Pharmaceuticals, Inc. | Derivados arilo y heteroarilo 1,2,3-trisustituidos como moduladores del metabolismo, y profilaxis y tratamiento de transtornos relacionados con los mismos, tales como la diabetes y la hiperglucemia. |
| US20070066640A1 (en) * | 2003-01-16 | 2007-03-22 | Emiliano Castiglioni | Heteroaryl-substituted pyrrolo'2,3-b1 pyridine derivatives as crf receptor antagonists |
| GB0308208D0 (en) | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
| US7112585B2 (en) | 2003-04-18 | 2006-09-26 | Bristol-Myers Squibb Company | Pyrimidine derivatives as corticotropin releasing factor inhibitors |
| US7030145B2 (en) | 2003-04-18 | 2006-04-18 | Bristol-Myers Squibb Company | Pyridinyl derivatives for the treatment of depression |
| AR045047A1 (es) * | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| US7132426B2 (en) | 2003-07-14 | 2006-11-07 | Arena Pharmaceuticals, Inc. | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| US20050171095A1 (en) * | 2004-01-06 | 2005-08-04 | Pfizer Inc | Combination of CRF antagonists and 5-HT1B receptor antagonists |
| EP1701961A1 (en) * | 2004-01-06 | 2006-09-20 | Taisho Pharmaceutical Co., Ltd | Thienopyrimidine and thienopyridine derivatives substituted with cyclic amino group |
| MY139645A (en) | 2004-02-11 | 2009-10-30 | Amgen Inc | Vanilloid receptor ligands and their use in treatments |
| US7534798B2 (en) | 2004-02-11 | 2009-05-19 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| AP2006003771A0 (en) | 2004-04-30 | 2006-10-31 | Warner Lambert Co | Substituted morpholine compounds for the treatmentof central nervous system disorders |
| DE602005019874D1 (de) * | 2004-05-12 | 2010-04-22 | Bristol Myers Squibb Co | Für die behandlung von thrombotischen leiden geeignete harnstoffantagonisten des p2y1-rezeptors |
| MX2007003330A (es) | 2004-09-20 | 2007-06-05 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como agentes terapeuticos. |
| WO2006089311A1 (en) | 2005-02-15 | 2006-08-24 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| US8153791B2 (en) | 2005-12-21 | 2012-04-10 | Janssen Pharmaceutica N.V. | Substituted pyrimidinyl oxime kinase inhibitors |
| US8013153B2 (en) * | 2006-03-23 | 2011-09-06 | Janssen Pharmaceutica, N.V. | Substituted pyrimidine kinase inhibitors |
| DK2076508T3 (da) | 2006-10-18 | 2011-02-21 | Pfizer Prod Inc | Biaryl-ether-urinstof-forbindelser |
| WO2009144632A1 (en) * | 2008-05-30 | 2009-12-03 | Pfizer Limited | Novel compounds |
| GB0913636D0 (en) * | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
| EP2619198A1 (en) | 2010-09-22 | 2013-07-31 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| AP2015008844A0 (en) | 2013-06-27 | 2015-11-30 | Pfizer | Heteroaromatic compounds and their use as dopamined1 ligands |
| PL3242666T3 (pl) | 2015-01-06 | 2025-02-17 | Arena Pharmaceuticals, Inc. | Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1 |
| SG11201707246YA (en) | 2015-03-06 | 2017-10-30 | Pharmakea Inc | Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof |
| WO2016144702A1 (en) | 2015-03-06 | 2016-09-15 | Pharmakea, Inc. | Lysyl oxidase-like 2 inhibitors and uses thereof |
| JP6838744B2 (ja) | 2015-06-22 | 2021-03-03 | アリーナ ファーマシューティカルズ, インコーポレイテッド | S1P1レセプター関連障害における使用のための(R)−2−(7−(4−シクロペンチル−3−(トリフルオロメチル)ベンジルオキシ)−1,2,3,4−テトラヒドロシクロペンタ[b]インドール−3−イル)酢酸(化合物1)の結晶性L−アルギニン塩 |
| JP6975514B2 (ja) * | 2016-07-08 | 2021-12-01 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 縮合ピリミジン誘導体 |
| US11077108B2 (en) * | 2016-09-07 | 2021-08-03 | The Regents Of The University Of California | Allosteric corticotropin-releasing factor receptor 1 (CRFR1) antagonists that decrease p-tau and improve cognition |
| BR112019004517A2 (pt) | 2016-09-07 | 2019-08-13 | Pharmakea, Inc. | formas cristalinas de um inibidor lisil-oxidase-semelhante 2 e métodos de preparação |
| KR102615565B1 (ko) | 2016-09-07 | 2023-12-18 | 파마케아, 인크. | 리실 옥시다제 유사 2 억제제의 용도 |
| AU2018220521A1 (en) | 2017-02-16 | 2019-09-05 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of primary biliary cholangitis |
| FI3609868T3 (fi) | 2017-03-13 | 2023-11-22 | Raqualia Pharma Inc | Tetrahydrokinoliinijohdannaisia P2X7-reseptorin antagonisteina |
| KR102859841B1 (ko) | 2018-06-06 | 2025-09-12 | 아레나 파마슈티칼스, 인크. | S1p1 수용체와 관련된 병태의 치료 방법 |
| WO2020168068A1 (en) * | 2019-02-13 | 2020-08-20 | The University Of Vermont And State Agricultural College | Small molecule antagonist to pacap receptor and uses thereof |
| EP4054608A4 (en) * | 2019-11-06 | 2024-02-21 | Albert Einstein College of Medicine | LOW MOLECULAR PROSTAGLADINE TRANSPORT INHIBITORS |
| EP4604945A2 (en) * | 2022-10-18 | 2025-08-27 | Merck Sharp & Dohme LLC | Novel kv3 channel modulators |
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| DE3145287A1 (de) | 1981-11-14 | 1983-05-19 | Troponwerke GmbH & Co KG, 5000 Köln | Pyrrolo (2.3-d)pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4605642A (en) | 1984-02-23 | 1986-08-12 | The Salk Institute For Biological Studies | CRF antagonists |
| EP0264883A3 (en) | 1986-10-21 | 1990-04-04 | Banyu Pharmaceutical Co., Ltd. | Substituted pyridine derivatives |
| US5063245A (en) | 1990-03-28 | 1991-11-05 | Nova Pharmaceutical Corporation | Corticotropin-releasing factor antagonism compounds |
| CA2051012C (en) | 1990-09-14 | 2002-04-02 | David R. Borcherding | Carbocyclic adenosine analogs useful as immunosupressants |
| DE59303950D1 (de) | 1992-08-10 | 1996-10-31 | Volkswagen Ag | Schalteinrichtung für ein Getriebe |
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| CN1142817A (zh) * | 1993-10-12 | 1997-02-12 | 杜邦麦克制药有限公司 | 1n-烷基-n-芳基嘧啶胺及其衍生物 |
| TW574214B (en) * | 1994-06-08 | 2004-02-01 | Pfizer | Corticotropin releasing factor antagonists |
| US5691364A (en) | 1995-03-10 | 1997-11-25 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| US6403599B1 (en) * | 1995-11-08 | 2002-06-11 | Pfizer Inc | Corticotropin releasing factor antagonists |
| PA8467401A1 (es) * | 1998-02-17 | 2000-09-29 | Pfizer Prod Inc | Procedimiento para tratar la insuficiencia cardiaca |
| US6130188A (en) * | 1998-05-05 | 2000-10-10 | American Cyanamid Company | Herbicidal pyridine compounds |
| EP1040831A3 (en) * | 1999-04-02 | 2003-05-02 | Pfizer Products Inc. | Use of corticotropin releasing factor (CRF) antagonists to prevent sudden death |
| US6387894B1 (en) * | 1999-06-11 | 2002-05-14 | Pfizer Inc. | Use of CRF antagonists and renin-angiotensin system inhibitors |
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- 2001-01-05 AU AU23905/01A patent/AU779995B2/en not_active Ceased
- 2001-01-05 CN CN01803846A patent/CN1395566A/zh active Pending
- 2001-01-05 YU YU54402A patent/YU54402A/sh unknown
- 2001-01-05 JP JP2001553267A patent/JP2003520272A/ja active Pending
- 2001-01-05 EP EP01900209A patent/EP1263732A1/en not_active Withdrawn
- 2001-01-05 CZ CZ20022390A patent/CZ20022390A3/cs unknown
- 2001-01-05 AP APAP/P/2002/002583A patent/AP2002002583A0/en unknown
- 2001-01-05 EA EA200200688A patent/EA200200688A1/ru unknown
- 2001-01-05 EA EA200300834A patent/EA200300834A1/ru unknown
- 2001-01-05 PL PL01357589A patent/PL357589A1/xx not_active Application Discontinuation
- 2001-01-05 SK SK1006-2002A patent/SK10062002A3/sk unknown
- 2001-01-05 CA CA002397633A patent/CA2397633A1/en not_active Abandoned
- 2001-01-05 BR BR0107662-0A patent/BR0107662A/pt not_active IP Right Cessation
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- 2001-01-16 PE PE2001000038A patent/PE20011166A1/es not_active Application Discontinuation
- 2001-01-16 AR ARP010100176A patent/AR027221A1/es not_active Application Discontinuation
- 2001-01-17 US US09/761,995 patent/US6833378B2/en not_active Expired - Fee Related
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- 2001-01-17 CO CO01003117A patent/CO5271658A1/es not_active Application Discontinuation
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- 2002-07-11 MA MA26728A patent/MA26864A1/fr unknown
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