NO20016067D0 - Fremgangsmåte for fremstilling av IL-8-reseptor-antagonister - Google Patents
Fremgangsmåte for fremstilling av IL-8-reseptor-antagonisterInfo
- Publication number
- NO20016067D0 NO20016067D0 NO20016067A NO20016067A NO20016067D0 NO 20016067 D0 NO20016067 D0 NO 20016067D0 NO 20016067 A NO20016067 A NO 20016067A NO 20016067 A NO20016067 A NO 20016067A NO 20016067 D0 NO20016067 D0 NO 20016067D0
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- receptor antagonists
- antagonists
- receptor
- Prior art date
Links
- 108090001007 Interleukin-8 Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2341496P | 1996-08-15 | 1996-08-15 | |
| PCT/US1997/014581 WO1998006397A1 (en) | 1996-08-15 | 1997-08-15 | Il-8 receptor antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20016067L NO20016067L (no) | 1999-04-12 |
| NO20016067D0 true NO20016067D0 (no) | 2001-12-12 |
| NO314301B1 NO314301B1 (no) | 2003-03-03 |
Family
ID=21814968
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19990668A NO312458B1 (no) | 1996-08-15 | 1999-02-12 | IL-8-reseptor antagonister, fremgangsmåte for fremstilling derav og farmasöytisk preparat |
| NO20016067A NO314301B1 (no) | 1996-08-15 | 2001-12-12 | Fremgangsmåte for fremstilling av IL-8-reseptor-antagonister |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19990668A NO312458B1 (no) | 1996-08-15 | 1999-02-12 | IL-8-reseptor antagonister, fremgangsmåte for fremstilling derav og farmasöytisk preparat |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6204294B1 (no) |
| EP (1) | EP0929302A4 (no) |
| JP (1) | JP2000516619A (no) |
| KR (1) | KR20000030003A (no) |
| CN (1) | CN1152675C (no) |
| AR (1) | AR008290A1 (no) |
| AU (1) | AU723816B2 (no) |
| BR (1) | BR9711140A (no) |
| CA (1) | CA2263388A1 (no) |
| CO (1) | CO5031286A1 (no) |
| CZ (1) | CZ46799A3 (no) |
| IL (1) | IL128501A0 (no) |
| NO (2) | NO312458B1 (no) |
| PL (1) | PL331539A1 (no) |
| TR (1) | TR199900318T2 (no) |
| TW (1) | TW461878B (no) |
| WO (1) | WO1998006397A1 (no) |
| ZA (1) | ZA977301B (no) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2255858C (en) | 1996-05-24 | 2007-09-11 | Neurosearch A/S | Phenyl derivatives containing an acidic group, their preparation and their use as chloride channel blockers |
| WO1997049400A1 (en) | 1996-06-27 | 1997-12-31 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| WO1998006399A1 (en) * | 1996-08-15 | 1998-02-19 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| CA2245224A1 (en) * | 1998-08-14 | 2000-02-14 | Jiang-Hong Giong | Chemokine receptor antagonists and chemotherapeutics |
| WO1999047158A2 (en) | 1998-03-13 | 1999-09-23 | The University Of British Columbia | Therapeutic chemokine receptor antagonists |
| CA2305787A1 (en) * | 2000-05-09 | 2001-11-09 | The University Of British Columbia | Cxcr4 antagonist treatment of hematopoietic cells |
| AR029361A1 (es) * | 1999-05-28 | 2003-06-25 | Smithkline Beecham Corp | Compuestos de guanidina ciclicas antagonistas de los receptores de la il- 8, composicion farmaceutica que los comprende y el uso de los mismos para la manufactura de un medicamento |
| AR029637A1 (es) * | 1999-05-28 | 2003-07-10 | Smithkline Beecham Corp | Compuestos de guanidina, antagonistas de los receptores de la il-8, una composicion farmaceutica que los contiene y el uso de los mismos para la manufactura de un medicamento |
| ECSP003525A (es) * | 1999-06-16 | 2002-01-25 | Smithkline Beecham Corp | Antagonistas del receptor de il- 8 iv |
| UY26627A1 (es) * | 2000-03-24 | 2001-09-28 | Smithkline Beecham Corp | Antagonistas de receptores de il-8 |
| US7378098B2 (en) * | 2000-04-12 | 2008-05-27 | The University Of British Columbia | CXC chemokine receptor 4 agonist peptides |
| US20050059584A1 (en) * | 2002-08-16 | 2005-03-17 | Ahmed Merzouk | Novel chemokine mimetics synthesis and their use |
| CA2335109A1 (en) * | 2000-04-12 | 2001-10-12 | Chemokine Therapeutics Corporation | Cxcr4 agonist treatment of hematopoietic cells |
| US7368425B2 (en) * | 2006-03-24 | 2008-05-06 | Chemokine Therapeutics Corp. | Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis |
| WO2001079168A1 (en) | 2000-04-14 | 2001-10-25 | Kureha Chemical Industry Co., Ltd. | Nitrogenous compounds and antiviral drugs containing the same |
| US6515001B2 (en) | 2001-03-05 | 2003-02-04 | Chemokine Therapeutic Corporation | IL-8 receptor ligands-drugs for inflammatory and autoimmune diseases |
| CN1630517A (zh) * | 2001-05-24 | 2005-06-22 | 吴羽化学工业株式会社 | 包含含氮化合物的具有cxcr4拮抗作用的药物 |
| US7176227B2 (en) | 2002-09-11 | 2007-02-13 | Kureha Corporation | Amine compounds and use thereof |
| TW200418812A (en) * | 2002-10-29 | 2004-10-01 | Smithkline Beecham Corp | IL-8 receptor antagonists |
| CA2558600C (en) * | 2004-03-10 | 2013-07-09 | Kureha Corporation | A substituted-trialkyl amine compound with anti-viral activity based on antagonism against a chemokine receptor cxcr4 |
| MXPA06013118A (es) | 2004-05-12 | 2007-02-28 | Schering Corp | Antagonistas de cxcr1 y cxcr2 de quimocina. |
| EP1634573A1 (en) * | 2004-08-16 | 2006-03-15 | The Procter and Gamble Company | 2-(Amino or substituted Amino)-5,6-substituted Phenol compounds, dyeing compositions containing them, and use thereof |
| WO2006023435A1 (en) * | 2004-08-16 | 2006-03-02 | The Procter & Gamble Company | 2-(amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof |
| EP1812008A4 (en) * | 2004-10-20 | 2008-10-29 | Smithkline Beecham Corp | ANTAGONISTS OF THE IL-8 RECEPTOR |
| JP2009534420A (ja) * | 2006-04-21 | 2009-09-24 | スミスクライン・ビーチャム・コーポレイション | Il−8受容体アンタゴニスト |
| WO2007124424A2 (en) * | 2006-04-21 | 2007-11-01 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| PE20080943A1 (es) * | 2006-06-23 | 2008-09-27 | Smithkline Beecham Corp | Sal toluenosulfonato de 4-{[6-cloro-3-({[(2-cloro-3-fluorofenil)amino]carbonil}amino)-2-hidroxifenil]sulfonil}-1-piperazinacarboxilato de 1,1-dimetiletilo como antagonista del receptor de il-8 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US537186A (en) * | 1895-04-09 | Jacob ebert | ||
| US4269837A (en) * | 1980-02-19 | 1981-05-26 | Pfizer Inc. | Hypoglycemic guanylamidines, compositions and use |
| NZ229828A (en) * | 1988-08-09 | 1992-03-26 | Squibb & Sons Inc | Aryl cyanoguanidine derivatives and pharmaceutical compositions |
| JP2742084B2 (ja) * | 1989-03-13 | 1998-04-22 | キヤノン株式会社 | グアニジン二量化物およびグアニジン二量化物を含有する静電荷像現像用トナー |
| US5214208A (en) * | 1989-03-13 | 1993-05-25 | Canon Kabushiki Kaisha | Toner containing a dimer of diarylguanidine type compound for developing electrostatic image |
| US5792444A (en) * | 1989-05-09 | 1998-08-11 | The General Hospital Corporation | Labeled chemotactic peptides to image focal sites of infection or inflammation |
| US5371086A (en) | 1991-03-15 | 1994-12-06 | The Green Cross Corporation | Aminopyridine compounds |
| AU4530693A (en) | 1992-08-13 | 1994-03-15 | Upjohn Company, The | Cyanoguanidines as potassium channel blockers |
| DK41193D0 (da) * | 1993-04-07 | 1993-04-07 | Neurosearch As | Ionkanalaabnere |
| US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
-
1997
- 1997-08-12 AR ARP970103665A patent/AR008290A1/es not_active Application Discontinuation
- 1997-08-14 ZA ZA9707301A patent/ZA977301B/xx unknown
- 1997-08-15 IL IL12850197A patent/IL128501A0/xx unknown
- 1997-08-15 US US09/230,977 patent/US6204294B1/en not_active Expired - Fee Related
- 1997-08-15 CA CA002263388A patent/CA2263388A1/en not_active Abandoned
- 1997-08-15 TR TR1999/00318T patent/TR199900318T2/xx unknown
- 1997-08-15 KR KR1019997001283A patent/KR20000030003A/ko not_active Ceased
- 1997-08-15 JP JP10510106A patent/JP2000516619A/ja not_active Ceased
- 1997-08-15 CZ CZ99467A patent/CZ46799A3/cs unknown
- 1997-08-15 CN CNB971986037A patent/CN1152675C/zh not_active Expired - Fee Related
- 1997-08-15 CO CO97047171A patent/CO5031286A1/es unknown
- 1997-08-15 AU AU40750/97A patent/AU723816B2/en not_active Ceased
- 1997-08-15 EP EP19970938425 patent/EP0929302A4/en not_active Withdrawn
- 1997-08-15 BR BR9711140A patent/BR9711140A/pt not_active Application Discontinuation
- 1997-08-15 WO PCT/US1997/014581 patent/WO1998006397A1/en not_active Ceased
- 1997-08-15 PL PL97331539A patent/PL331539A1/xx unknown
- 1997-10-03 TW TW086111871A patent/TW461878B/zh not_active IP Right Cessation
-
1999
- 1999-02-12 NO NO19990668A patent/NO312458B1/no not_active IP Right Cessation
-
2001
- 2001-12-12 NO NO20016067A patent/NO314301B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20016067L (no) | 1999-04-12 |
| CN1232398A (zh) | 1999-10-20 |
| PL331539A1 (en) | 1999-07-19 |
| US6204294B1 (en) | 2001-03-20 |
| IL128501A0 (en) | 2000-01-31 |
| EP0929302A1 (en) | 1999-07-21 |
| NO314301B1 (no) | 2003-03-03 |
| NO990668D0 (no) | 1999-02-12 |
| TW461878B (en) | 2001-11-01 |
| CO5031286A1 (es) | 2001-04-27 |
| WO1998006397A1 (en) | 1998-02-19 |
| KR20000030003A (ko) | 2000-05-25 |
| CZ46799A3 (cs) | 1999-12-15 |
| ZA977301B (en) | 1998-02-16 |
| JP2000516619A (ja) | 2000-12-12 |
| AU723816B2 (en) | 2000-09-07 |
| CN1152675C (zh) | 2004-06-09 |
| BR9711140A (pt) | 1999-08-17 |
| TR199900318T2 (xx) | 1999-05-21 |
| EP0929302A4 (en) | 2002-10-31 |
| NO312458B1 (no) | 2002-05-13 |
| CA2263388A1 (en) | 1998-02-19 |
| NO990668L (no) | 1999-04-12 |
| AU4075097A (en) | 1998-03-06 |
| AR008290A1 (es) | 1999-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |