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NO20015481L - Nye indikasjoner på mannanbindende lectin (MBL) ved behandlingen av immunkompromitterte individer - Google Patents

Nye indikasjoner på mannanbindende lectin (MBL) ved behandlingen av immunkompromitterte individer

Info

Publication number
NO20015481L
NO20015481L NO20015481A NO20015481A NO20015481L NO 20015481 L NO20015481 L NO 20015481L NO 20015481 A NO20015481 A NO 20015481A NO 20015481 A NO20015481 A NO 20015481A NO 20015481 L NO20015481 L NO 20015481L
Authority
NO
Norway
Prior art keywords
treatment
mbl
mannan
prophylaxis
binding lectin
Prior art date
Application number
NO20015481A
Other languages
English (en)
Norwegian (no)
Other versions
NO20015481D0 (no
Inventor
Steffen Thiel
Jens Christian Jensenius
Original Assignee
Jens Christian Jensenius
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jens Christian Jensenius filed Critical Jens Christian Jensenius
Publication of NO20015481D0 publication Critical patent/NO20015481D0/no
Publication of NO20015481L publication Critical patent/NO20015481L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Filtering Materials (AREA)
  • Wrappers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO20015481A 1999-05-14 2001-11-08 Nye indikasjoner på mannanbindende lectin (MBL) ved behandlingen av immunkompromitterte individer NO20015481L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199900668 1999-05-14
DKPA199901508 1999-10-20
PCT/DK2000/000247 WO2000069894A2 (en) 1999-05-14 2000-05-10 Novel indications of mannan-binding lectin (mbl) in the treatment of immunocompromised individuals

Publications (2)

Publication Number Publication Date
NO20015481D0 NO20015481D0 (no) 2001-11-08
NO20015481L true NO20015481L (no) 2002-01-11

Family

ID=26064419

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20015481A NO20015481L (no) 1999-05-14 2001-11-08 Nye indikasjoner på mannanbindende lectin (MBL) ved behandlingen av immunkompromitterte individer
NO20015506A NO20015506L (no) 1999-05-14 2001-11-09 Rekombinant humant mannanbindende lectin

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20015506A NO20015506L (no) 1999-05-14 2001-11-09 Rekombinant humant mannanbindende lectin

Country Status (15)

Country Link
US (5) US6562784B1 (de)
EP (3) EP1181038B1 (de)
JP (2) JP2002543837A (de)
CN (2) CN1359298A (de)
AT (3) ATE352620T1 (de)
AU (2) AU779404B2 (de)
CA (2) CA2372435A1 (de)
DE (3) DE60030173T2 (de)
DK (3) DK1181038T3 (de)
ES (3) ES2281341T3 (de)
NO (2) NO20015481L (de)
NZ (2) NZ515718A (de)
PT (3) PT1181363E (de)
RU (2) RU2292217C2 (de)
WO (2) WO2000069894A2 (de)

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US6969601B2 (en) 1997-04-03 2005-11-29 Jensenius Jens Chr MASP-2, a complement-fixing enzyme, and uses for it
ES2281341T3 (es) * 1999-05-14 2007-10-01 Steffen Thiel Lectina humana recombinante que se une a manano.
EP1303288A1 (de) * 2000-07-13 2003-04-23 Natimmune A/S Mannan-bindendes lektin (mbl) zur behandlung von infektionen in tnf alphabehandelte individen
EP1186299A1 (de) * 2000-09-12 2002-03-13 Universitair Medisch Centrum Utrecht Diagnose, Verbeugung und/oder Behandlung von Atherosklerose, Infectionen und Störungen des Immunsystems
AU2002218154A1 (en) * 2000-11-27 2002-06-03 Jens Christian Jensenius Collectins as adjuvants
US20040192589A1 (en) * 2001-07-23 2004-09-30 Finn Matthiesen Production of high molecular mass lectins
WO2003018617A1 (fr) * 2001-08-31 2003-03-06 Fuso Pharmaceutical Industries, Ltd. Procede de purification de lectine liant le mannose humain, compositions de lectine liant le mannose humain et utilisation medicale de la lectine liant le mannose humain
DE60207678T2 (de) * 2001-10-19 2006-08-24 Natimmune A/S Isolierung von lectinen
AU2003215524A1 (en) * 2002-03-15 2003-09-29 Natimmune A/S Pharmaceutical compositions comprising mannose binding lectin
US7211396B2 (en) 2002-04-18 2007-05-01 Antibodyshop A/S Antibody pairs and kits for immunochemical determination of mannan-binding lectin
CN1646152A (zh) * 2002-04-24 2005-07-27 昆士兰医学研究学院理事会 甘露糖结合凝集素及其应用
JPWO2004002511A1 (ja) * 2002-06-28 2005-10-27 扶桑薬品工業株式会社 抗ｈｉｖ剤
JP2005537807A (ja) * 2002-09-10 2005-12-15 ナットイムネ・アクティーゼルスカブ コレクチン補体活性化タンパク質キメラ
GB0222014D0 (en) * 2002-09-23 2002-10-30 Leuven K U Res & Dev Mannan-binding lectin
US7226429B2 (en) * 2003-01-17 2007-06-05 Aethlon Medical, Inc. Method for removal of viruses from blood by lectin affinity hemodialysis
DK2374819T3 (en) 2003-05-12 2017-06-06 Helion Biotech Aps Antibodies against MASP-2
US7135338B2 (en) * 2003-06-11 2006-11-14 Dobeel Corporation Methods for overexpression of high molecular weight form of mannose binding lectin (MBL) and a specific formulation for active treatment for systemic infection with microorganism
DE20317914U1 (de) 2003-11-19 2004-12-30 Weh, Erwin Betätigungsvorrichtung für eine Schnellanschlusskupplung
US7335633B2 (en) 2004-01-12 2008-02-26 Cornell Research Foundation, Inc. Detecting recurrent vulvovaginal candidiasis or vulvar vestibulitis syndrome and method for treating same
CA2555989A1 (en) * 2004-02-24 2005-09-01 Innogenetics N.V. Method for determining the risk of developing a neurological disease
US7964559B2 (en) 2004-03-09 2011-06-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services MVL, an antiviral protein from a cyanobacterium
US7919094B2 (en) * 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
EP1618887A1 (de) * 2004-07-12 2006-01-25 UMC Utrecht Holding B.V. Beseitigung von Polyolen aus dem Körper
WO2006035024A1 (en) * 2004-09-29 2006-04-06 Mellitus, S.L. Method for detecting a predisposition to develop gestational diabetes mellitus and treatment for this disease
EP1833502B1 (de) * 2004-12-23 2011-03-02 Council of Scientific and Industrial Research Pharmazeutische zusammensetzung zur behandlung von invasiver lungenaspergillose
CN101094651B (zh) * 2004-12-30 2011-03-09 多贝尔有限公司 含有胶原凝集素家族蛋白质或者其变体的喷雾干燥的组合物和其制备方法
WO2006108417A2 (en) * 2005-04-11 2006-10-19 Natimmune A/S Mannan-binding lectin (mbl) in the treatment of immunocompromised conditions associated with cancer
WO2007044642A2 (en) 2005-10-06 2007-04-19 President And Fellows Of Harvard College And Children's Medical Center Corporation Device and method for combined microfluidic-micromagnetic separation of material in continuous flow
DK2380587T3 (en) 2005-12-21 2017-12-04 Pharming Intellectual Property B V Use of a C1 inhibitor to prevent ischemia-reperfusion injury
WO2007085057A1 (en) * 2006-01-25 2007-08-02 The Council Of The Queensland Institute Of Medical Research A medical protocol
US20070226567A1 (en) * 2006-03-23 2007-09-27 Gorman Kevin W High speed bist utilizing clock multiplication
US20110052428A1 (en) * 2008-01-16 2011-03-03 Superpar Otomotiv Sanayi Ve Ticaret Anonim Sirketi Electric fuel pump for heavy duty engine platforms
WO2009126346A2 (en) * 2008-01-18 2009-10-15 The General Hospital Corporation Methods for prevention and treatment of infections with supraphysiological doses of mannan-binding lectin (mbl) and ficolin-mbl fusion proteins
US9156037B2 (en) 2009-01-15 2015-10-13 Children's Medical Center Corporation Microfluidic device and uses thereof
AU2011207626B2 (en) * 2010-01-19 2015-06-18 President And Fellows Of Harvard College Engineered opsonin for pathogen detection and treatment
US20120328568A1 (en) 2010-02-12 2012-12-27 Emory University Compositions and uses of lectins
DE102011003478A1 (de) * 2011-02-01 2012-08-02 Cytavis Biopharma Gmbh Antivirales Mittel enthaltend rekombinante Mistellektine
EP2734843A2 (de) 2011-07-18 2014-05-28 President and Fellows of Harvard College Manipulierte moleküle zur anzielung von mikroben und ihre verwendungen
HK1206066A1 (en) 2012-02-29 2015-12-31 President And Fellows Of Harvard College Rapid antibiotic susceptibility testing
EP3327090A1 (de) 2012-07-18 2018-05-30 President and Fellows of Harvard College Modifizierung von oberflächen zur gleichzeitigen abweisung und gezielten bindung gewünschter gruppen
WO2014144325A1 (en) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Methods and compositions for improving detection and/or capture of a target entity
WO2014190040A1 (en) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
US10513546B2 (en) 2013-12-18 2019-12-24 President And Fellows Of Harvard College CRP capture/detection of gram positive bacteria
WO2016077067A2 (en) * 2014-10-27 2016-05-19 President And Fellows Of Harvard College Magnetic capture of a target from a fluid
WO2017024114A1 (en) 2015-08-06 2017-02-09 President And Fellows Of Harvard College Improved microbe-binding molecules and uses thereof
US11919971B2 (en) 2016-05-16 2024-03-05 President And Fellows Of Harvard College Aqueous biomolecule coupling on CO2-plasma-activated surfaces
CN107050436B (zh) * 2017-02-27 2020-03-17 新乡医学院 Mbl在制备预防或治疗效应t细胞引发疾病药物中的应用
CN107050427A (zh) * 2017-02-27 2017-08-18 新乡医学院 MBL在制备预防或治疗以Tregs为靶点的疾病药物中的应用
WO2019110706A1 (en) * 2017-12-08 2019-06-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of developing a sepsis or a systemic inflammatory response syndrome (sirs)
RU2739113C1 (ru) * 2019-10-04 2020-12-21 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр терапии и профилактической медицины" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТПМ" Минздрава России) Способ определения активности маннан-связывающих лектин-ассоциированных сериновых протеаз в тесте коагуляции фибриногена
WO2023087090A1 (en) * 2021-11-18 2023-05-25 Magellan Therapeutics Inc. Recombinant proteins

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FI900808A7 (fi) * 1987-08-20 1990-02-19 Childrens Medical Center Ihmisen mannoosia sitova proteiini
US5270199A (en) 1987-08-20 1993-12-14 The Children's Medical Center Corporation Human mannose-binding protein
US5112952A (en) 1990-09-28 1992-05-12 Pierce Chemical Company Composition and method for isolation and purification of Immunoglobulin M
EP0856580A4 (de) 1995-08-17 2001-02-07 Fuso Pharmaceutical Ind Rekombinantes conglutinin und verfahren zu dessen herstellung
JP3990736B2 (ja) 1997-08-21 2007-10-17 タカラバイオ株式会社 制がん剤
CA2334696C (en) 1998-06-10 2014-03-25 Statens Serum Institut Purification process for production of mannan-binding lectin and an mbl medicinal product
ES2281341T3 (es) * 1999-05-14 2007-10-01 Steffen Thiel Lectina humana recombinante que se une a manano.

Also Published As

Publication number Publication date
WO2000069894A2 (en) 2000-11-23
ES2281341T3 (es) 2007-10-01
EP1181363B1 (de) 2007-01-24
EP1402897A3 (de) 2004-06-30
AU4393600A (en) 2000-12-05
US7439224B2 (en) 2008-10-21
DE60030173D1 (de) 2006-09-28
CN1359420A (zh) 2002-07-17
WO2000069894A3 (en) 2001-02-08
US6562784B1 (en) 2003-05-13
CA2372128A1 (en) 2000-11-23
NO20015506L (no) 2002-01-09
US20030191052A1 (en) 2003-10-09
ATE352620T1 (de) 2007-02-15
JP2002543837A (ja) 2002-12-24
EP1181038A2 (de) 2002-02-27
RU2005125625A (ru) 2007-02-20
DE60009896T2 (de) 2005-04-21
DK1181363T3 (da) 2007-05-29
ATE264111T1 (de) 2004-04-15
US6846649B1 (en) 2005-01-25
PT1402897E (pt) 2007-01-31
WO2000070043A1 (en) 2000-11-23
DK1402897T3 (da) 2006-12-27
ES2219336T3 (es) 2004-12-01
PT1181038E (pt) 2004-08-31
DE60009896D1 (de) 2004-05-19
EP1181363A1 (de) 2002-02-27
CA2372435A1 (en) 2000-11-23
US20040229212A1 (en) 2004-11-18
DE60030173T2 (de) 2007-08-23
DK1181038T3 (da) 2004-08-09
AU779404B2 (en) 2005-01-20
NO20015481D0 (no) 2001-11-08
PT1181363E (pt) 2007-05-31
EP1181038B1 (de) 2004-04-14
EP1402897B1 (de) 2006-08-16
DE60033147T2 (de) 2007-12-13
JP2002544286A (ja) 2002-12-24
AU4393500A (en) 2000-12-05
CN1359298A (zh) 2002-07-17
NO20015506D0 (no) 2001-11-09
RU2292217C2 (ru) 2007-01-27
US7202207B2 (en) 2007-04-10
EP1402897A2 (de) 2004-03-31
NZ515717A (en) 2004-01-30
DE60033147D1 (de) 2007-03-15
AU781135B2 (en) 2005-05-05
US20070197428A1 (en) 2007-08-23
ES2271468T3 (es) 2007-04-16
ATE336260T1 (de) 2006-09-15
NZ515718A (en) 2004-03-26

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