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NO20006230L - Hyperforinderivater, anvendelsen derav og formuleringer inneholdende dem - Google Patents

Hyperforinderivater, anvendelsen derav og formuleringer inneholdende dem

Info

Publication number
NO20006230L
NO20006230L NO20006230A NO20006230A NO20006230L NO 20006230 L NO20006230 L NO 20006230L NO 20006230 A NO20006230 A NO 20006230A NO 20006230 A NO20006230 A NO 20006230A NO 20006230 L NO20006230 L NO 20006230L
Authority
NO
Norway
Prior art keywords
formulations containing
hyperforin derivatives
hyperforin
derivatives
glicoside
Prior art date
Application number
NO20006230A
Other languages
English (en)
Other versions
NO328444B1 (no
NO20006230D0 (no
Inventor
Ezio Bombardelli
Paolo Marazzoni
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO20006230D0 publication Critical patent/NO20006230D0/no
Publication of NO20006230L publication Critical patent/NO20006230L/no
Publication of NO328444B1 publication Critical patent/NO328444B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/647Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring
    • C07C49/653Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring polycyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/013Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
NO20006230A 1998-06-10 2000-12-07 Hyperforinderivat, anvendelse derav og farmasoytisk sammensetning inneholdende det NO328444B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI001312A IT1301679B1 (it) 1998-06-10 1998-06-10 Derivati dell'iperforina, loro uso e formulazioni che licontengono.
PCT/EP1999/003880 WO1999064388A1 (en) 1998-06-10 1999-06-04 Hyperforin derivatives, the use thereof and formulations containing them

Publications (3)

Publication Number Publication Date
NO20006230D0 NO20006230D0 (no) 2000-12-07
NO20006230L true NO20006230L (no) 2001-02-01
NO328444B1 NO328444B1 (no) 2010-02-22

Family

ID=11380210

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006230A NO328444B1 (no) 1998-06-10 2000-12-07 Hyperforinderivat, anvendelse derav og farmasoytisk sammensetning inneholdende det

Country Status (22)

Country Link
US (1) US6656510B2 (no)
EP (2) EP1607099A1 (no)
JP (1) JP4511726B2 (no)
KR (1) KR100627933B1 (no)
CN (1) CN1246278C (no)
AT (1) ATE307103T1 (no)
AU (1) AU763889B2 (no)
BR (1) BR9910893B1 (no)
CA (1) CA2334308C (no)
CZ (1) CZ298859B6 (no)
DE (1) DE69927813T2 (no)
DK (1) DK1086071T3 (no)
ES (1) ES2249893T3 (no)
HU (1) HUP0102226A3 (no)
IL (2) IL140151A0 (no)
IT (1) IT1301679B1 (no)
MX (1) MXPA00012177A (no)
NO (1) NO328444B1 (no)
PL (1) PL195797B1 (no)
RU (1) RU2240304C2 (no)
SK (1) SK286049B6 (no)
WO (1) WO1999064388A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1126882B1 (de) * 1998-11-04 2009-12-30 Dr. Willmar Schwabe GmbH & Co. KG Stabile zubereitungen mit hyperforin
ITMI20020872A1 (it) 2002-04-23 2003-10-23 Indena Spa Derivati dell'iperforina loro uso e formulazioni che li contengono
ITMI20020871A1 (it) * 2002-04-23 2003-10-23 Indena Spa Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono
US20060115555A1 (en) * 2004-12-01 2006-06-01 Foulger Sidney W Nutritional supplements containing xanthone extracts
US20060115556A1 (en) * 2004-12-01 2006-06-01 Foulger Sidney W Nutritional supplement drink containing xanthone extracts
BRPI0900614A2 (pt) 2009-02-13 2011-06-28 Univ Fed Do Rio Grande Do Sul Ufrgs extrato vegetal neuroativo, composição farmacêutica compreendendo o mesmo e processo para sua produção
RU2013157954A (ru) 2011-06-03 2015-07-20 Президентс Энд Феллоуз Оф Гарвард Колледж Аналоги гиперфорина, способы их синтеза и применения
ITMI20131012A1 (it) 2013-06-19 2014-12-20 Indena Spa Derivati dell'iperforina e loro uso nella malattia di alzheimer
RU2676100C1 (ru) * 2018-10-05 2018-12-26 федеральное государственное автономное образовательное учреждение высшего образования "Санкт-Петербургский политехнический университет Петра Великого" (ФГАОУ ВО "СПбПУ") Применение производных пиперазина для лечения болезни Альцгеймера и деменций альцгеймеровского типа с нарушенной внутриклеточной кальциевой сигнализацией
CN118724815A (zh) * 2024-06-20 2024-10-01 中日友好医院(中日友好临床医学研究所) 一种间苯三酚类化合物Hyperforidiol E及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2550266A (en) * 1948-12-11 1951-04-24 Swift & Co Preservation of food products
DE4239959A1 (de) * 1992-11-27 1994-06-01 Schwabe Willmar Gmbh & Co Johanniskraut-Trockenextrakt, Verfahren zu seiner Herstellung und seine Verwendung
DE19646977A1 (de) * 1995-09-29 1998-01-15 Schwabe Willmar Gmbh & Co Stabiler Extrakt aus Hypericum perforatum L., Verfahren zu seiner Herstellung und pharmazeutische Zubereitungen
DE19714450A1 (de) * 1997-04-08 1998-10-15 Schwabe Willmar Gmbh & Co Stabiler Extrakt aus Hypericum perforatum L., Verfahren zu seiner Herstellung und pharmazeutische Zubereitung
US6096317A (en) * 1998-01-13 2000-08-01 Rexall Sundown St. John's Wort and methyl donor composition and uses thereof
US6224906B1 (en) * 1999-08-31 2001-05-01 Natreon Inc. St. John's wort composition

Also Published As

Publication number Publication date
ES2249893T3 (es) 2006-04-01
DE69927813T2 (de) 2006-04-20
JP4511726B2 (ja) 2010-07-28
RU2240304C2 (ru) 2004-11-20
IL140151A0 (en) 2002-02-10
IT1301679B1 (it) 2000-07-07
CZ298859B6 (cs) 2008-02-27
WO1999064388A1 (en) 1999-12-16
CN1304397A (zh) 2001-07-18
PL195797B1 (pl) 2007-10-31
MXPA00012177A (es) 2004-09-06
BR9910893A (pt) 2001-03-06
EP1086071A1 (en) 2001-03-28
US20010020040A1 (en) 2001-09-06
PL344696A1 (en) 2001-11-19
ATE307103T1 (de) 2005-11-15
CA2334308C (en) 2009-06-02
CN1246278C (zh) 2006-03-22
HUP0102226A3 (en) 2003-07-28
DK1086071T3 (da) 2006-01-23
ITMI981312A1 (it) 1999-12-10
NO328444B1 (no) 2010-02-22
KR20010052637A (ko) 2001-06-25
EP1086071B1 (en) 2005-10-19
NO20006230D0 (no) 2000-12-07
AU4373999A (en) 1999-12-30
BR9910893B1 (pt) 2013-10-29
HUP0102226A2 (hu) 2001-10-28
CZ20004562A3 (en) 2001-06-13
JP2002517478A (ja) 2002-06-18
HK1036791A1 (en) 2002-01-18
SK18712000A3 (sk) 2001-06-11
DE69927813D1 (de) 2006-03-02
IL140151A (en) 2006-12-10
AU763889B2 (en) 2003-07-31
SK286049B6 (sk) 2008-01-07
EP1607099A1 (en) 2005-12-21
CA2334308A1 (en) 1999-12-16
KR100627933B1 (ko) 2006-09-22
US6656510B2 (en) 2003-12-02

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