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NO20005951L - Fremgangsmåte for rensning av Borrelia lipoprotein OspA - Google Patents

Fremgangsmåte for rensning av Borrelia lipoprotein OspA

Info

Publication number
NO20005951L
NO20005951L NO20005951A NO20005951A NO20005951L NO 20005951 L NO20005951 L NO 20005951L NO 20005951 A NO20005951 A NO 20005951A NO 20005951 A NO20005951 A NO 20005951A NO 20005951 L NO20005951 L NO 20005951L
Authority
NO
Norway
Prior art keywords
purification
procedure
lipoprotein ospa
borrelia
borrelia lipoprotein
Prior art date
Application number
NO20005951A
Other languages
English (en)
Other versions
NO20005951D0 (no
Inventor
Pierre Desmons
Robert Liveyns
Emmanuel Mertens
Benoit Champluvier
Dominique Plainchamp
Yvon Corazza
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of NO20005951D0 publication Critical patent/NO20005951D0/no
Publication of NO20005951L publication Critical patent/NO20005951L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer en fremgangsmåte for rensning av Borrelia-lipoprotein-OspA egnet for human klinisk anvendelse hvori en vertcelle som uttrykker lipoprotein-OspA lyseres ved tilstedeværelse av zwitterjonisk detergent etterfulgt av flere kromatografiske trinn i et ikke-jonisk detergent.
NO20005951A 1998-05-26 2000-11-24 Fremgangsmåte for rensning av Borrelia lipoprotein OspA NO20005951L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9811219.6A GB9811219D0 (en) 1998-05-26 1998-05-26 Novel process
PCT/EP1999/003602 WO1999061473A1 (en) 1998-05-26 1999-05-25 Method for purification of borrelia lipoprotein ospa

Publications (2)

Publication Number Publication Date
NO20005951D0 NO20005951D0 (no) 2000-11-24
NO20005951L true NO20005951L (no) 2001-01-24

Family

ID=10832669

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005951A NO20005951L (no) 1998-05-26 2000-11-24 Fremgangsmåte for rensning av Borrelia lipoprotein OspA

Country Status (17)

Country Link
EP (1) EP1080109B1 (no)
JP (1) JP2002516340A (no)
KR (1) KR20010043817A (no)
CN (1) CN1311795A (no)
AT (1) ATE244730T1 (no)
AU (1) AU752196B2 (no)
BR (1) BR9910715A (no)
CA (1) CA2333167A1 (no)
DE (1) DE69909469T2 (no)
GB (1) GB9811219D0 (no)
HU (1) HUP0102774A3 (no)
IL (1) IL139749A0 (no)
NO (1) NO20005951L (no)
PL (1) PL345273A1 (no)
TR (1) TR200003468T2 (no)
WO (1) WO1999061473A1 (no)
ZA (1) ZA200006873B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA99719C2 (ru) 2006-11-03 2012-09-25 Шеринг-Плау Лтд. Вакцина для собак против болезни лайма
US8293876B2 (en) * 2007-02-22 2012-10-23 Baxter International Inc. Method of purification of hydrophobic proteins
KR102230562B1 (ko) 2010-05-14 2021-03-22 박스알타 인코퍼레이티드 Ospa 키메라 및 백신에서 그의 용도
KR20150038380A (ko) 2012-07-27 2015-04-08 백스터 인터내셔널 인코포레이티드 키메라 ospa 분자를 포함하는 조성물 및 이의 사용 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) * 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
US6221363B1 (en) * 1991-07-11 2001-04-24 Baxter Aktiengesellschaft Vaccine for the prevention of lyme disease
AU676140B2 (en) * 1991-10-18 1997-03-06 Connaught Laboratories Inc. Preparation of recombinant borrelia proteins

Also Published As

Publication number Publication date
HUP0102774A2 (hu) 2001-11-28
BR9910715A (pt) 2001-01-30
AU4367999A (en) 1999-12-13
EP1080109A1 (en) 2001-03-07
CN1311795A (zh) 2001-09-05
WO1999061473A1 (en) 1999-12-02
KR20010043817A (ko) 2001-05-25
HUP0102774A3 (en) 2003-04-28
EP1080109B1 (en) 2003-07-09
NO20005951D0 (no) 2000-11-24
GB9811219D0 (en) 1998-07-22
ZA200006873B (en) 2001-07-05
DE69909469T2 (de) 2004-04-15
DE69909469D1 (de) 2003-08-14
JP2002516340A (ja) 2002-06-04
TR200003468T2 (tr) 2002-05-21
IL139749A0 (en) 2002-02-10
ATE244730T1 (de) 2003-07-15
PL345273A1 (en) 2001-12-03
AU752196B2 (en) 2002-09-12
CA2333167A1 (en) 1999-12-02

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application