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NO20002849L - Sammensetninger og metoder for Õ indusere genekspersjon - Google Patents

Sammensetninger og metoder for Õ indusere genekspersjon

Info

Publication number
NO20002849L
NO20002849L NO20002849A NO20002849A NO20002849L NO 20002849 L NO20002849 L NO 20002849L NO 20002849 A NO20002849 A NO 20002849A NO 20002849 A NO20002849 A NO 20002849A NO 20002849 L NO20002849 L NO 20002849L
Authority
NO
Norway
Prior art keywords
compositions
methods
gene expression
inducing gene
inducing
Prior art date
Application number
NO20002849A
Other languages
English (en)
Other versions
NO20002849D0 (no
Inventor
Richard J Gregory
Karen Vincent
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of NO20002849D0 publication Critical patent/NO20002849D0/no
Publication of NO20002849L publication Critical patent/NO20002849L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20002849A 1997-12-04 2000-06-02 Sammensetninger og metoder for Õ indusere genekspersjon NO20002849L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6754697P 1997-12-04 1997-12-04
US13361298A 1998-08-13 1998-08-13
PCT/US1998/025753 WO1999028469A1 (en) 1997-12-04 1998-12-04 Compositions and methods for inducing gene expression

Publications (2)

Publication Number Publication Date
NO20002849D0 NO20002849D0 (no) 2000-06-02
NO20002849L true NO20002849L (no) 2000-08-02

Family

ID=26747998

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002849A NO20002849L (no) 1997-12-04 2000-06-02 Sammensetninger og metoder for Õ indusere genekspersjon

Country Status (9)

Country Link
US (3) US6432927B1 (no)
EP (1) EP1034267A1 (no)
JP (2) JP2001525173A (no)
AU (1) AU749467B2 (no)
CA (1) CA2311643C (no)
IL (2) IL136454A0 (no)
NO (1) NO20002849L (no)
NZ (1) NZ504847A (no)
WO (1) WO1999028469A1 (no)

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* Cited by examiner, † Cited by third party
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WO1999028469A1 (en) * 1997-12-04 1999-06-10 Genzyme Corporation Compositions and methods for inducing gene expression
US6124131A (en) * 1998-08-25 2000-09-26 The Johns Hopkins University School Of Medicine Mutant hypoxia inducible factor-1 HIF-1
FR2801319A1 (fr) * 1999-11-18 2001-05-25 Inst Nat Sante Rech Med Construction d'acide nucleique porteuse d'un systeme regulant l'expression d'un gene
CN1425075A (zh) * 2000-02-22 2003-06-18 牛津生物医学（英国）有限公司 差异表达筛选方法
SE0002551D0 (sv) * 2000-07-06 2000-07-06 Pharmacia & Upjohn Ab Screening methods
US7214770B2 (en) 2000-07-06 2007-05-08 Angiogenetics Sweden Ab Screening Methods
CA2418386A1 (en) * 2000-08-07 2002-02-14 Angiogenetics Sweden Ab Mechanism of conditional regulation of the hypoxia-inducible factor-1 by the von hippel-lindau tumor suppressor protein
AU2002221542A1 (en) * 2000-11-07 2002-05-21 Max-Delbruck-Centrum Fur Molekulare Medizin Use of heart-specific transcription factors of the basic helix-loop-helix type for treating cardiac power failure
JP2004536572A (ja) 2001-02-23 2004-12-09 セル・ジェネシス・インコーポレイテッド 新規ベクター構築物
GB0107757D0 (en) * 2001-03-28 2001-05-16 Gendaq Ltd Gene regulation II
US7396922B2 (en) * 2001-11-28 2008-07-08 Angiogenetics Sweden Ab Regulation of hypoxia-inducible gene expression with antisense Inhibitory PAS domain protein
DK1463823T3 (da) * 2001-12-06 2013-06-03 Fibrogen Inc Fremgangsmåder til forhøjelse af endogent erythropoetin (epo)
WO2003066883A2 (en) * 2002-02-08 2003-08-14 The Regents Of The University Of California A transcription amplification system for molecular imaging
DE10245926B4 (de) * 2002-10-02 2005-04-07 Ab Elektronik Gmbh Bodenpedal mit Drehwinkelsensor
WO2004042025A2 (en) 2002-11-01 2004-05-21 Cell Genesys, Inc. Cell-specific adenovirus vector comprising ebv-specific promoter
US7144999B2 (en) * 2002-11-23 2006-12-05 Isis Pharmaceuticals, Inc. Modulation of hypoxia-inducible factor 1 alpha expression
US8124582B2 (en) 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US7618940B2 (en) * 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
WO2005001136A1 (en) * 2003-06-04 2005-01-06 Irm Llc Methods and compositions for modulating erythropoietin expression
US8614204B2 (en) * 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
US7822276B2 (en) * 2005-02-17 2010-10-26 Iris International, Inc. Method and apparatus for analyzing body fluids
CA2611785A1 (en) 2005-06-15 2006-12-28 Fibrogen, Inc. Use of hif 1alfa modulators for treatment of cancer
US20090215687A1 (en) * 2005-10-21 2009-08-27 Cornell Research Foundation, Inc. Compounds for Enhancing Hypoxia Inducible Factor Activity and Methods of Use
ES2619522T3 (es) * 2006-03-30 2017-06-26 Lg Electronics, Inc. Un método y un aparato para descodificar/codificar una señal de video multivisión
US7759306B2 (en) * 2006-05-16 2010-07-20 Simoni Jan S Methods of treating acute blood loss
ES2725552T3 (es) 2006-06-07 2019-09-24 Genzyme Corp Terapia génica para esclerosis lateral amiotrófica y otros trastornos de la médula espinal
WO2008033304A2 (en) * 2006-09-12 2008-03-20 Genzyme Corporation Compositions for promoting non-leaky collateral vascularization
US20080081354A1 (en) * 2006-10-02 2008-04-03 Cardiac Pacemakers, Inc. Devices, vectors and methods for inducible ischemia cardioprotection
LT2497500T (lt) 2006-10-03 2016-12-27 Genzyme Corporation Spinalinės raumenų atrofijos genų terapija
US8846053B2 (en) 2008-09-26 2014-09-30 Sdg, Inc. Orally bioavailable lipid-based constructs
US9145453B2 (en) * 2007-09-28 2015-09-29 Sdg, Inc. Orally bioavailable lipid-based constructs
US8962015B2 (en) * 2007-09-28 2015-02-24 Sdg, Inc. Orally bioavailable lipid-based constructs
HUE057606T2 (hu) 2009-05-02 2022-05-28 Genzyme Corp Génterápia neurodegeneratív rendellenességekre
EP2432481A2 (en) * 2009-05-21 2012-03-28 Stemcyte Inc. Cell therapy for brain tissue damage
US10351610B2 (en) * 2012-02-02 2019-07-16 Dow Agrosciences Llc Plant transactivation interaction motifs and uses thereof

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
WO1991019784A1 (en) 1990-06-13 1991-12-26 The Trustees Of Princeton University A Lac REPRESSOR-HSV VP16 CHIMERIC TRANSCRIPTIONAL ACTIVATOR PROTEIN SYSTEM FUNCTIONING IN TRANSFECTED MAMMALIAN CELLS
JP3337214B2 (ja) * 1990-12-20 2002-10-21 アーチ・ディベロップメント・コーポレーション 電離線による遺伝子発現の調節
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5834306A (en) * 1994-12-23 1998-11-10 Sri International Tissue specific hypoxia regulated therapeutic constructs
JP3961019B2 (ja) * 1995-02-28 2007-08-15 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 遺伝子転移媒介の血管形成療法
US5792453A (en) * 1995-02-28 1998-08-11 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
US5707618A (en) 1995-03-24 1998-01-13 Genzyme Corporation Adenovirus vectors for gene therapy
US5882914A (en) * 1995-06-06 1999-03-16 The Johns Hopkins University School Of Medicine Nucleic acids encoding the hypoxia inducible factor-1
US6306649B1 (en) * 1995-06-27 2001-10-23 Ariad Gene Therapeutics, Inc. Heterologous transcription factors
US6121246A (en) * 1995-10-20 2000-09-19 St. Elizabeth's Medical Center Of Boston, Inc. Method for treating ischemic tissue
US6133027A (en) * 1996-08-07 2000-10-17 City Of Hope Inducible expression system
US5695963A (en) * 1997-01-17 1997-12-09 Board Of Regents, The University Of Texas System Endothelial PAS domain protein
EP0990042A1 (en) 1997-06-10 2000-04-05 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Regulatory sequences involved in hypoxia regulated gene expression and uses thereof
US6087166A (en) * 1997-07-03 2000-07-11 Basf Aktiengesellschaft Transcriptional activators with graded transactivation potential
WO1999028469A1 (en) * 1997-12-04 1999-06-10 Genzyme Corporation Compositions and methods for inducing gene expression
US6124131A (en) * 1998-08-25 2000-09-26 The Johns Hopkins University School Of Medicine Mutant hypoxia inducible factor-1 HIF-1

Also Published As

Publication number Publication date
US20060127361A1 (en) 2006-06-15
NO20002849D0 (no) 2000-06-02
IL136454A0 (en) 2001-06-14
AU749467B2 (en) 2002-06-27
US20030018007A1 (en) 2003-01-23
JP2001525173A (ja) 2001-12-11
IL136454A (en) 2010-06-16
US7053062B2 (en) 2006-05-30
US6432927B1 (en) 2002-08-13
AU1626899A (en) 1999-06-16
NZ504847A (en) 2003-02-28
CA2311643A1 (en) 1999-06-10
JP2007195555A (ja) 2007-08-09
WO1999028469A1 (en) 1999-06-10
CA2311643C (en) 2009-04-07
EP1034267A1 (en) 2000-09-13

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