NO20000257L - Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksine - Google Patents
Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksineInfo
- Publication number
- NO20000257L NO20000257L NO20000257A NO20000257A NO20000257L NO 20000257 L NO20000257 L NO 20000257L NO 20000257 A NO20000257 A NO 20000257A NO 20000257 A NO20000257 A NO 20000257A NO 20000257 L NO20000257 L NO 20000257L
- Authority
- NO
- Norway
- Prior art keywords
- vaccine
- compositions
- modified immunogenic
- pneumolysin
- immunogenic pneumolysin
- Prior art date
Links
- 101710183389 Pneumolysin Proteins 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5330697P | 1997-07-21 | 1997-07-21 | |
| US7345698P | 1998-02-02 | 1998-02-02 | |
| PCT/US1998/014716 WO1999003884A2 (en) | 1997-07-21 | 1998-07-21 | Modified immunogenic pneumolysin, compositions and their use as vaccines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20000257D0 NO20000257D0 (no) | 2000-01-19 |
| NO20000257L true NO20000257L (no) | 2000-03-21 |
Family
ID=26731692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000257A NO20000257L (no) | 1997-07-21 | 2000-01-19 | Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksine |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6764686B2 (no) |
| EP (1) | EP0998557A2 (no) |
| JP (1) | JP2001510031A (no) |
| KR (1) | KR100619350B1 (no) |
| AU (1) | AU740956B2 (no) |
| CA (1) | CA2297374A1 (no) |
| HU (1) | HUP0002475A3 (no) |
| NO (1) | NO20000257L (no) |
| WO (1) | WO1999003884A2 (no) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| GB9906437D0 (en) * | 1999-03-19 | 1999-05-12 | Smithkline Beecham Biolog | Vaccine |
| DE122009000054I1 (de) | 1999-03-19 | 2009-12-31 | Glaxosmithkline Biolog Sa | Impfstoff gegen bakterielle antigene |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| US8771702B2 (en) * | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
| GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
| EP1524992B1 (en) | 2002-08-02 | 2015-03-04 | GlaxoSmithKline Biologicals s.a. | Vaccine compositions comprising l2 and/or l3 immunotype lipooligosaccharides from lgtb- neisseria menigitidis |
| AU2003287980B2 (en) | 2002-11-01 | 2009-06-25 | Glaxosmithkline Biologicals S.A. | Drying process |
| JP2006506989A (ja) * | 2002-11-07 | 2006-03-02 | シナジー アメリカ,インコーポレイテッド | 肺炎球菌感染を治療または予防するための組成物および方法 |
| KR101052996B1 (ko) | 2003-03-13 | 2011-07-29 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 박테리아 세포용해소에 대한 정제 공정 |
| EP1667712B1 (en) | 2003-10-02 | 2010-07-21 | GlaxoSmithKline Biologicals S.A. | B. pertussis antigens and use thereof in vaccination |
| WO2005076696A2 (en) * | 2004-02-13 | 2005-08-25 | Sanofi Pasteur Limited | Pneumolysin derivatives |
| GB0410220D0 (en) * | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
| WO2005108419A1 (en) * | 2004-05-07 | 2005-11-17 | Lea-Ann Kirkham | Mutant cholesterol-binding cytolysin proteins |
| WO2006021210A2 (en) * | 2004-08-23 | 2006-03-02 | Genesto A/S | Binding member towards pneumolysin |
| GB0421083D0 (en) * | 2004-09-22 | 2004-10-27 | Glaxosmithkline Biolog Sa | Purification process |
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| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| KR101441368B1 (ko) | 2005-12-22 | 2014-09-24 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 폐렴구균 다당류 컨쥬게이트 백신 |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| ZA200805602B (en) | 2006-01-17 | 2009-12-30 | Arne Forsgren | A novel surface exposed haemophilus influenzae protein (protein E; pE) |
| US9370557B2 (en) * | 2006-06-15 | 2016-06-21 | The University Court Of The University Of Glasgow | Adjuvant compounds |
| SI2484375T1 (en) | 2006-09-26 | 2018-08-31 | Infectious Disease Research Institute | A vaccine composition comprising a synthetic adjuvant |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| DK2086582T3 (da) | 2006-10-12 | 2013-02-04 | Glaxosmithkline Biolog Sa | Vaccine omfattende en olie-i-vand-emulsionsadjuvans |
| PL2086582T3 (pl) | 2006-10-12 | 2013-04-30 | Glaxosmithkline Biologicals Sa | Kompozycja zawierająca adiuwant w postaci emulsji typu olej w wodzie |
| US9717788B2 (en) | 2007-03-02 | 2017-08-01 | Glaxosmithkline Biologicals Sa | Method of inducing an immune response against HIV employing HIV immunogens, adenoviral vectors encoding said immunogens, and adjuvant |
| EP2998316B1 (en) | 2007-03-02 | 2019-06-12 | GlaxoSmithKline Biologicals S.A. | Novel method and compositions |
| AU2008287286B2 (en) | 2007-04-13 | 2013-10-10 | The Board Of Regents Of The University Of Oklahoma | Mutants of cholesterol-dependent cytolysins and uses thereof |
| DK2167121T3 (en) | 2007-06-26 | 2015-11-23 | Glaxosmithkline Biolog Sa | A vaccine comprising Streptococcus pneumoniae kapselpolysaccharidkonjugater |
| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| HUE026586T2 (hu) | 2008-04-16 | 2016-06-28 | Glaxosmithkline Biologicals Sa | Vakcina |
| EP2293815A4 (en) * | 2008-05-22 | 2013-04-03 | Childrens Medical Center | SYNERGISTIC IMMUNOGENIC FUSION PROTEIN POLYSACCHARIDE CONJUGATE |
| GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
| CN106008679A (zh) * | 2008-12-24 | 2016-10-12 | 荷兰王国卫生福利和运动部国家公共卫生和环境研究所 | 修饰的肺炎链球菌溶血素(ply)多肽 |
| CN102438649A (zh) | 2009-03-24 | 2012-05-02 | 诺华有限公司 | 脑膜炎球菌h因子结合蛋白和肺炎球菌结合糖的组合物 |
| HRP20161585T1 (hr) | 2009-06-05 | 2016-12-30 | Infectious Disease Research Institute | Sintetski glukopiranozilni lipidi kao adjuvansi i cjepivni pripravci koji ih sadrže |
| EP2475385A1 (en) | 2009-09-10 | 2012-07-18 | Novartis AG | Combination vaccines against respiratory tract diseases |
| GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| WO2011112717A1 (en) | 2010-03-09 | 2011-09-15 | Biomedical Research Models, Inc. | A novel mucosal vaccination approach for herpes simplex virus type-2 |
| US20130004530A1 (en) | 2010-03-10 | 2013-01-03 | Jan Poolman | Vaccine composition |
| WO2011112906A2 (en) * | 2010-03-12 | 2011-09-15 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
| KR101958753B1 (ko) | 2010-04-13 | 2019-03-15 | 셀덱스 쎄라퓨틱스, 인크. | 인간 cd27에 결합하는 항체 및 이의 용도 |
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| AU2011336366B2 (en) | 2010-12-03 | 2016-05-12 | Sanofi Pasteur Limited | Composition for immunization against Streptococcus pneumoniae |
| GB201022007D0 (en) | 2010-12-24 | 2011-02-02 | Imp Innovations Ltd | DNA-sensor |
| CA2832307A1 (en) | 2011-04-08 | 2012-10-18 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| US20140072622A1 (en) * | 2011-05-17 | 2014-03-13 | Glaxosmithkline Biologicals S.A. | Vaccine against streptococcus pneumoniae |
| US20140294930A1 (en) | 2011-08-04 | 2014-10-02 | The Regents Of The University Of California | STREPTOCOCCAL GlcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM |
| EP2811981B1 (en) | 2012-02-07 | 2019-05-08 | Infectious Disease Research Institute | Improved adjuvant formulations comprising tlr4 agonists and methods of using the same |
| CN104519910B (zh) | 2012-03-07 | 2017-05-03 | 诺华股份有限公司 | 肺炎链球菌抗原的含佐剂制剂 |
| ES2673556T3 (es) | 2012-05-16 | 2018-06-22 | Immune Design Corp. | Vacunas para el VHS-2 |
| US20140193451A1 (en) * | 2012-10-17 | 2014-07-10 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| WO2014107731A1 (en) | 2013-01-07 | 2014-07-10 | Biomedical Research Models, Inc. | Therapeutic vaccines for treating herpes simplex virus type 2 infections |
| WO2014124228A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| EP3711768A1 (en) | 2013-04-18 | 2020-09-23 | Immune Design Corp. | Gla monotherapy for use in cancer treatment |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| JP6741580B2 (ja) | 2013-12-31 | 2020-08-19 | インフェクシャス ディズィーズ リサーチ インスティチュート | 単一バイアルのワクチン製剤 |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| ES2993430T3 (en) | 2014-11-21 | 2024-12-30 | Univ Oklahoma | Pneumolysin mutants and methods of use thereof |
| US20180044429A1 (en) | 2015-03-09 | 2018-02-15 | Celldex Therapeutics, Inc. | Cd27 agonists |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| WO2017176076A1 (en) | 2016-04-06 | 2017-10-12 | Ewha University - Industry Collaboration Foundation | A peptide with ability to penetrate cell membrane |
| EP3445783A2 (en) | 2016-04-18 | 2019-02-27 | Celldex Therapeutics, Inc. | Agonistic antibodies that bind human cd40 and uses thereof |
| KR102392974B1 (ko) | 2016-05-16 | 2022-05-02 | 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) | Tlr 작용제를 함유하는 제제 및 사용 방법 |
| IL263030B2 (en) | 2016-05-16 | 2024-11-01 | Access To Advanced Health Inst | Pegylated liposomes and methods of use |
| RU2753874C2 (ru) | 2016-06-01 | 2021-08-24 | Инфекшес Дизис Рисёрч Инститьют | Наноалюмочастицы, содержащие агент, регулирующий размер |
| GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| US20200038499A1 (en) * | 2017-03-22 | 2020-02-06 | Modernatx, Inc. | Rna bacterial vaccines |
| ES3003260T3 (en) | 2017-06-15 | 2025-03-10 | Access To Advanced Health Inst | Nanostructured lipid carriers and stable emulsions and uses thereof |
| CN111315406A (zh) | 2017-09-08 | 2020-06-19 | 传染病研究所 | 包括皂苷的脂质体调配物及其使用方法 |
| US11459393B2 (en) | 2018-04-17 | 2022-10-04 | Celldex Therapeutics, Inc. | Anti-CD27 and anti-PD-L1 antibodies and bispecific constructs |
| CN112969474A (zh) | 2018-09-12 | 2021-06-15 | 艾芬尼维克斯公司 | 多价肺炎球菌疫苗 |
| US20220016168A1 (en) | 2018-12-11 | 2022-01-20 | Celldex Therapeutics, Inc. | Methods of using cd27 antibodies as conditioning treatment for adoptive cell therapy |
| CN113227125A (zh) | 2018-12-12 | 2021-08-06 | 葛兰素史密丝克莱恩生物有限公司 | 用于o-连接的糖基化的修饰的载体蛋白 |
| MX2021014363A (es) | 2019-05-25 | 2022-02-21 | Infectious Disease Res Inst | Composicion y metodo para secar por pulverizacion una emulsion de vacuna adyuvante. |
| AU2021337493A1 (en) | 2020-09-04 | 2023-05-18 | Access To Advanced Health Institute | Co-lyophilized rna and nanostructured lipid carrier |
| KR20240006541A (ko) | 2021-04-09 | 2024-01-15 | 셀덱스 쎄라퓨틱스, 인크. | Ilt4에 대한 항체, 이중특이적 항-ilt4/pd-l1 항체 및 이의 용도 |
| US12036276B2 (en) | 2021-09-09 | 2024-07-16 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
| WO2023077521A1 (en) | 2021-11-08 | 2023-05-11 | Celldex Therapeutics, Inc | Anti-ilt4 and anti-pd-1 bispecific constructs |
| WO2024052882A1 (en) | 2022-09-09 | 2024-03-14 | Access To Advanced Health Institute | Immunogenic vaccine composition incorporating a saponin |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2160570T3 (es) * | 1988-12-16 | 2001-11-16 | Nederlanden Staat | Mutantes de neumolisina y vacunas de neumococos fabricadas a partir de los mismos. |
| CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| EP0687688A1 (en) | 1993-12-17 | 1995-12-20 | Universidad De Oviedo | Antibodies against pneumolysine and their applications |
| US5565204A (en) * | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| US6019982A (en) * | 1994-08-26 | 2000-02-01 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
| CA2262748A1 (en) * | 1996-08-12 | 1998-02-19 | Board Of Regents, The University Of Texas System | Defining epitopes of the outer membrane protein copb of moraxella catarrhalis |
-
1998
- 1998-07-21 US US09/120,044 patent/US6764686B2/en not_active Expired - Fee Related
- 1998-07-21 HU HU0002475A patent/HUP0002475A3/hu unknown
- 1998-07-21 WO PCT/US1998/014716 patent/WO1999003884A2/en not_active Ceased
- 1998-07-21 JP JP2000503106A patent/JP2001510031A/ja active Pending
- 1998-07-21 AU AU84078/98A patent/AU740956B2/en not_active Ceased
- 1998-07-21 EP EP98934590A patent/EP0998557A2/en not_active Withdrawn
- 1998-07-21 CA CA002297374A patent/CA2297374A1/en not_active Abandoned
- 1998-07-21 KR KR1020007000844A patent/KR100619350B1/ko not_active Expired - Fee Related
-
2000
- 2000-01-19 NO NO20000257A patent/NO20000257L/no not_active Application Discontinuation
-
2004
- 2004-02-23 US US10/785,673 patent/US20050070695A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010022271A (ko) | 2001-03-15 |
| US20010014332A1 (en) | 2001-08-16 |
| KR100619350B1 (ko) | 2006-09-05 |
| HUP0002475A3 (en) | 2002-01-28 |
| NO20000257D0 (no) | 2000-01-19 |
| HUP0002475A2 (hu) | 2000-10-28 |
| EP0998557A2 (en) | 2000-05-10 |
| CA2297374A1 (en) | 1999-01-28 |
| AU8407898A (en) | 1999-02-10 |
| WO1999003884A2 (en) | 1999-01-28 |
| WO1999003884A3 (en) | 1999-04-08 |
| US6764686B2 (en) | 2004-07-20 |
| US20050070695A1 (en) | 2005-03-31 |
| AU740956B2 (en) | 2001-11-15 |
| JP2001510031A (ja) | 2001-07-31 |
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