NO171852C - Analogifremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser med to substituerte 5-leddede ringer - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser med to substituerte 5-leddede ringer

Info

Publication number: NO171852C
Authority: NO; Norway
Prior art keywords: substituted; preparation; therapeutically active; ring rings; analogy procedure
Prior art date: 1986-09-22

Application number

NO873640A

Other languages

English (en)

Norwegian (no)

Other versions

NO171852B (no

NO873640L (no

NO873640D0 (no

Inventor

Takao Takaya

Kazuo Sakane

Kenzi Miyai

Kohji Kawabata

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-22

Filing date

1987-08-28

Publication date

1993-05-12

1986-09-22 Priority claimed from GB868622766A external-priority patent/GB8622766D0/en

1986-11-24 Priority claimed from GB868628061A external-priority patent/GB8628061D0/en

1987-03-04 Priority claimed from GB878705072A external-priority patent/GB8705072D0/en

1987-05-18 Priority claimed from GB878711653A external-priority patent/GB8711653D0/en

1987-07-13 Priority claimed from GB878716437A external-priority patent/GB8716437D0/en

1987-08-28 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1987-08-28 Publication of NO873640D0 publication Critical patent/NO873640D0/no

1988-03-23 Publication of NO873640L publication Critical patent/NO873640L/no

1993-02-01 Publication of NO171852B publication Critical patent/NO171852B/no

1993-05-12 Publication of NO171852C publication Critical patent/NO171852C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO873640A 1986-09-22 1987-08-28 Analogifremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser med to substituerte 5-leddede ringer NO171852C (no)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
GB868622766A GB8622766D0 (en)	1986-09-22	1986-09-22	Cephem compounds
GB868628061A GB8628061D0 (en)	1986-11-24	1986-11-24	Cephem compounds
GB878705072A GB8705072D0 (en)	1987-03-04	1987-03-04	Cephem compounds
GB878711653A GB8711653D0 (en)	1987-05-18	1987-05-18	Cephem compounds
GB878716437A GB8716437D0 (en)	1987-07-13	1987-07-13	Cephem compounds

Publications (4)

Publication Number	Publication Date
NO873640D0 NO873640D0 (no)	1987-08-28
NO873640L NO873640L (no)	1988-03-23
NO171852B NO171852B (no)	1993-02-01
NO171852C true NO171852C (no)	1993-05-12

Family

ID=27516672

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO873640A NO171852C (no)	1986-09-22	1987-08-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser med to substituerte 5-leddede ringer

Country Status (19)

Country	Link
US (2)	US4927818A (fi)
EP (1)	EP0261615B1 (fi)
JP (2)	JPH064647B2 (fi)
KR (1)	KR950013566B1 (fi)
CN (1)	CN87106452A (fi)
AU (2)	AU607157B2 (fi)
CA (1)	CA1293719C (fi)
DE (1)	DE3788261T2 (fi)
DK (1)	DK460087A (fi)
ES (1)	ES2061462T3 (fi)
FI (1)	FI87925C (fi)
HU (1)	HU202540B (fi)
IE (1)	IE872329L (fi)
IL (1)	IL83760A (fi)
NO (1)	NO171852C (fi)
NZ (1)	NZ221843A (fi)
OA (1)	OA08665A (fi)
PH (1)	PH23767A (fi)
PT (1)	PT85762B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ198350A (en) *	1980-09-25	1985-02-28	Toyama Chemical Co Ltd	Cephalosporins and intermediates;pharmaceutical compositions
CA1293719C (en) *	1986-09-22	1991-12-31	Takao Takaya	Cephem compounds and processes for preparation thereof
US5162520A (en) *	1986-09-22	1992-11-10	Fujisawa Pharmaceutical Co., Ltd.	Intermediates for cephem compounds
IL86941A (en) *	1987-07-10	1993-07-08	Gist Brocades Nv	Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process
US5210080A (en) *	1987-09-07	1993-05-11	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
US5663163A (en) *	1987-09-07	1997-09-02	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds and processes for preparation thereof
GB8905301D0 (en) *	1989-03-08	1989-04-19	Fujisawa Pharmaceutical Co	New cephem compound and a process for preparation thereof
KR910015587A (ko) *	1990-02-27	1991-09-30	후지사와 토모키치로	세펨 화합물
US5604222A (en) *	1993-12-27	1997-02-18	Lupin Laboratories, Ltd.	Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) *	1994-07-11	1996-11-26	Lupin Laboratories Limited	Process for preparation of 3-exomethylene cepham sulfoxide esters
PL366507A1 (en) *	2001-05-01	2005-02-07	Fujisawa Pharmaceutical Co, Ltd.	Cephem compounds
ES2290498T7 (es) *	2002-10-30	2015-07-10	Astellas Pharma Inc.	Compuestos de cefem
AU2003902380A0 (en) *	2003-05-16	2003-06-05	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
KR20060069475A (ko) *	2003-09-18	2006-06-21	아스텔라스세이야쿠 가부시키가이샤	세펨 화합물
JP4758371B2 (ja) *	2007-02-23	2011-08-24	株式会社荻野精機製作所	動力伝達切換機構
PT3616695T (pt)	2011-09-09	2024-11-18	Merck Sharp & Dohme	Ceftolozano/tazobactam para tratar infeções intrapulmonares
US8809314B1 (en)	2012-09-07	2014-08-19	Cubist Pharmacueticals, Inc.	Cephalosporin compound
US8476425B1 (en)	2012-09-27	2013-07-02	Cubist Pharmaceuticals, Inc.	Tazobactam arginine compositions
CN102875572B (zh) *	2012-10-26	2014-07-30	四川科伦药物研究有限公司	一种硫酸头孢噻利中间体的精制方法
CN110279698B (zh)	2013-03-15	2022-10-28	默沙东有限责任公司	头孢特咯瓒抗生素组合物
US20140274990A1 (en)	2013-03-15	2014-09-18	Cubist Pharmaceuticals, Inc.	Ceftolozane pharmaceutical compositions
US9872906B2 (en)	2013-03-15	2018-01-23	Merck Sharp & Dohme Corp.	Ceftolozane antibiotic compositions
CN105377812B (zh)	2013-06-21	2018-09-18	组合化学工业株式会社	2-氨基-2-肟基-n-烷氧基亚氨代乙酰基氰化物的制备方法及其制备中间体
ES2800603T3 (es)	2013-09-09	2021-01-04	Merck Sharp & Dohme	Tratamiento de infecciones con ceftolozano/tazobactam en sujetos con insuficiencia renal
US8906898B1 (en)	2013-09-27	2014-12-09	Calixa Therapeutics, Inc.	Solid forms of ceftolozane
WO2015196077A1 (en) *	2014-06-20	2015-12-23	Merck Sharp & Dohme Corp.	Reactions of thiadiazolyl-oximinoacetic acid derivative compounds

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4268509A (en) *	1978-07-10	1981-05-19	Fujisawa Pharmaceutical Co., Ltd.	New cephem compounds and processes for preparation thereof
DK480679A (da) *	1978-11-15	1980-05-16	Glaxo Group Ltd	Fremgangsmaade til fremstilling af cephalosporinforbindelser
US4390534A (en) *	1978-12-29	1983-06-28	Fujisawa Pharmaceutical Co., Ltd.	Cephem and cepham compounds
US4332800A (en) *	1979-10-12	1982-06-01	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
ZA816321B (en) *	1980-09-12	1982-09-29	Ciba Geigy	Ammoniomethyl compounds,processes for their manufacture,pharmaceutical preparations that contain these compounds,and the use of these compounds
GR78245B (fi) *	1980-09-12	1984-09-26	Ciba Geigy Ag
US4431642A (en) *	1980-12-01	1984-02-14	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
JPS584789A (ja) *	1981-04-03	1983-01-11	Fujisawa Pharmaceut Co Ltd	新規セフエム化合物およびその製造法
ES511101A0 (es) *	1981-04-03	1983-05-01	Fujisawa Pharmaceutical Co	"procedimiento para preparar un nuevo compuesto de cefem".
GR75487B (fi) *	1981-06-22	1984-07-23	Fujisawa Pharmaceutical Co
US4521413A (en) *	1981-09-14	1985-06-04	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
US4563449A (en) *	1982-07-19	1986-01-07	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
DE3419012A1 (de) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
PH22107A (en) *	1984-06-07	1988-06-01	Takeda Chemical Industries Ltd	3-pyrazolo(1,5-a)pyrdinium cephem compounds
JPS61286389A (ja) *	1985-06-11	1986-12-16	Eisai Co Ltd	セフエム系化合物
CN86107947A (zh) *	1985-11-22	1987-05-27	藤沢药品工业株式会社	新的头孢烯化合物及其制备方法
CA1293719C (en) *	1986-09-22	1991-12-31	Takao Takaya	Cephem compounds and processes for preparation thereof
IE63094B1 (en) *	1987-09-14	1995-03-22	Fujisawa Pharmaceutical Co	Cephem compound and a process for preparation thereof

1987
- 1987-08-26 CA CA000545415A patent/CA1293719C/en not_active Expired - Fee Related
- 1987-08-28 NO NO873640A patent/NO171852C/no unknown
- 1987-08-28 US US07/090,345 patent/US4927818A/en not_active Expired - Fee Related
- 1987-08-31 PH PH35750A patent/PH23767A/en unknown
- 1987-08-31 IE IE872329A patent/IE872329L/xx unknown
- 1987-09-02 IL IL83760A patent/IL83760A/xx not_active IP Right Cessation
- 1987-09-03 DK DK460087A patent/DK460087A/da not_active Application Discontinuation
- 1987-09-09 JP JP62225787A patent/JPH064647B2/ja not_active Expired - Lifetime
- 1987-09-17 NZ NZ221843A patent/NZ221843A/xx unknown
- 1987-09-18 AU AU78671/87A patent/AU607157B2/en not_active Ceased
- 1987-09-19 DE DE87113726T patent/DE3788261T2/de not_active Expired - Fee Related
- 1987-09-19 EP EP87113726A patent/EP0261615B1/en not_active Expired - Lifetime
- 1987-09-19 ES ES87113726T patent/ES2061462T3/es not_active Expired - Lifetime
- 1987-09-21 CN CN198787106452A patent/CN87106452A/zh active Pending
- 1987-09-21 PT PT85762A patent/PT85762B/pt not_active IP Right Cessation
- 1987-09-21 HU HU874258A patent/HU202540B/hu unknown
- 1987-09-21 FI FI874102A patent/FI87925C/fi not_active IP Right Cessation
- 1987-09-21 KR KR1019870010461A patent/KR950013566B1/ko not_active Expired - Fee Related
- 1987-09-22 OA OA59199A patent/OA08665A/xx unknown
1989
- 1989-09-06 US US07/403,406 patent/US5108997A/en not_active Expired - Fee Related
1990
- 1990-11-28 AU AU67077/90A patent/AU642929B2/en not_active Ceased
1993
- 1993-06-25 JP JP5154852A patent/JPH0680064B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
PT85762B (pt)	1990-07-31
DE3788261T2 (de)	1994-04-07
EP0261615B1 (en)	1993-11-24
NO171852B (no)	1993-02-01
FI87925C (fi)	1993-03-10
NO873640L (no)	1988-03-23
PT85762A (en)	1987-10-01
FI874102A0 (fi)	1987-09-21
EP0261615A3 (en)	1989-09-20
FI87925B (fi)	1992-11-30
IE872329L (en)	1988-03-22
IL83760A (en)	1993-04-04
AU7867187A (en)	1988-03-24
DE3788261D1 (de)	1994-01-05
PH23767A (en)	1989-11-03
HUT45071A (en)	1988-05-30
DK460087D0 (da)	1987-09-03
JPH0656846A (ja)	1994-03-01
DK460087A (da)	1988-03-23
HU202540B (en)	1991-03-28
NO873640D0 (no)	1987-08-28
CN87106452A (zh)	1988-05-04
IL83760A0 (en)	1988-02-29
KR880003958A (ko)	1988-06-01
ES2061462T3 (es)	1994-12-16
JPH0680064B2 (ja)	1994-10-12
AU642929B2 (en)	1993-11-04
JPS6399079A (ja)	1988-04-30
AU6707790A (en)	1991-02-14
NZ221843A (en)	1989-08-29
US4927818A (en)	1990-05-22
FI874102L (fi)	1988-03-23
OA08665A (en)	1988-11-30
CA1293719C (en)	1991-12-31
EP0261615A2 (en)	1988-03-30
JPH064647B2 (ja)	1994-01-19
US5108997A (en)	1992-04-28
AU607157B2 (en)	1991-02-28
KR950013566B1 (ko)	1995-11-09

Publication	Publication Date	Title
NO171852C (no)	1993-05-12	Analogifremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser med to substituerte 5-leddede ringer
NO801415L (no)	1980-11-17	Fremgangsmaate for fremstilling av antibakterielt aktive bisestere av metandiol med penicillinderivater
NO150206C (no)	1984-09-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive hoeyredreiende spiro-hydantoinforbindelser
NO844879L (no)	1985-06-07	Analogifremgangsmaate for fremstilling av terapeutisk aktive indolderivater
NO168174C (no)	1992-01-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive triazolforbindelser
NO872946D0 (no)	1987-07-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzensulfonamidoindanylforbindelser.
NO172581C (no)	1993-08-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske ketoner
NO162113C (no)	1989-11-08	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenetanolaminforbindelser.
NO171913C (no)	1993-05-19	Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske forbindelser
NO810762L (no)	1981-09-09	Fremgangsmaate for fremstilling av farmakologisk aktive heterocykliske forbindelser
NO780883L (no)	1978-09-15	Analogifremgangsmaate for fremstilling av farmakologisk aktive 4-acylamino-fenyl-etanolaminer
NO864879D0 (no)	1986-12-04	Fremgangsmaate for fremstilling av terapeutisk aktive tiasolforbindelser.
NO914490D0 (no)	1991-11-15	Analogifremgangsmaate for fremstilling av terapeutisk virksomme tricykliske forbindelser
NO169438C (no)	1992-06-24	Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrazolforbindelser
NO168362C (no)	1992-02-12	Analogifremgangsmaate for fremstilling av terapeutisk aktive peptidforbindelser
NO151201C (no)	1985-02-27	Fremgangsmaate for fremstilling av terapeutisk virksomme antigenderivater
NO820493L (no)	1982-08-19	Analogifremgangsmaate for fremstilling av farmakologisk aktive azepinderivater
NO871867D0 (no)	1987-05-05	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske kondenserte tricykliske forbindelser.
NO172849C (no)	1993-09-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazol- og oksazol-derivater
NO145762C (no)	1982-05-26	Analogifremgangsmaate for fremstilling av terapeutisk aktive antracyklinglykosidiske forbindelser
NO152255C (no)	1985-08-28	Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazolylvinylethere
NO165842C (no)	1991-04-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser.
NO834729L (no)	1984-06-25	Fremgangsmaate for fremstilling av farmakologisk aktive tio-cefalosporiner
NO170582C (no)	1992-11-04	Analogifremgangsmaate for fremstilling av terapeutisk aktive aryl-piperazinyl-alkylenfenyl-heterocykliske forbindelser
NO151239C (no)	1985-03-06	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-fenyliminoimidazolidiner