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NO177963C - Fremgangsmåte for fremstilling av nye insulinderivater - Google Patents

Fremgangsmåte for fremstilling av nye insulinderivater

Info

Publication number
NO177963C
NO177963C NO894424A NO894424A NO177963C NO 177963 C NO177963 C NO 177963C NO 894424 A NO894424 A NO 894424A NO 894424 A NO894424 A NO 894424A NO 177963 C NO177963 C NO 177963C
Authority
NO
Norway
Prior art keywords
insulin derivatives
amino acid
genetically encodable
formula
amide
Prior art date
Application number
NO894424A
Other languages
English (en)
Norwegian (no)
Other versions
NO894424L (no
NO894424D0 (no
NO177963B (no
Inventor
Michael Dorschug
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6366698&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO177963(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO894424D0 publication Critical patent/NO894424D0/no
Publication of NO894424L publication Critical patent/NO894424L/no
Publication of NO177963B publication Critical patent/NO177963B/no
Publication of NO177963C publication Critical patent/NO177963C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO894424A 1988-11-08 1989-11-07 Fremgangsmåte for fremstilling av nye insulinderivater NO177963C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3837825A DE3837825A1 (de) 1988-11-08 1988-11-08 Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Publications (4)

Publication Number Publication Date
NO894424D0 NO894424D0 (no) 1989-11-07
NO894424L NO894424L (no) 1990-05-09
NO177963B NO177963B (no) 1995-09-18
NO177963C true NO177963C (no) 1995-12-27

Family

ID=6366698

Family Applications (2)

Application Number Title Priority Date Filing Date
NO894424A NO177963C (no) 1988-11-08 1989-11-07 Fremgangsmåte for fremstilling av nye insulinderivater
NO2001023C NO2001023I1 (no) 1988-11-08 2001-11-29 Insulin glargin

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2001023C NO2001023I1 (no) 1988-11-08 2001-11-29 Insulin glargin

Country Status (22)

Country Link
US (2) US5656722A (fr)
EP (1) EP0368187B1 (fr)
JP (1) JP2680145B2 (fr)
KR (1) KR0158197B1 (fr)
AT (1) ATE93868T1 (fr)
AU (1) AU621680B2 (fr)
CA (1) CA1339044C (fr)
DE (3) DE3837825A1 (fr)
DK (1) DK173196B1 (fr)
ES (1) ES2059676T4 (fr)
FI (1) FI100185B (fr)
HK (1) HK1006171A1 (fr)
HU (2) HU213018B (fr)
IE (1) IE63338B1 (fr)
IL (1) IL92222A (fr)
LU (1) LU90614I2 (fr)
NL (1) NL300019I2 (fr)
NO (2) NO177963C (fr)
NZ (1) NZ231272A (fr)
PH (1) PH30695A (fr)
PT (1) PT92220B (fr)
ZA (1) ZA898456B (fr)

Families Citing this family (128)

* Cited by examiner, † Cited by third party
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US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
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FR3052072A1 (fr) 2016-06-07 2017-12-08 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
KR20240128130A (ko) 2016-12-05 2024-08-23 뉴리타스 리미티드 펩티드 wkdeagkplvk를 포함하는 조성물
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FR3083089A1 (fr) 2018-06-29 2020-01-03 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
WO2019110625A1 (fr) 2017-12-06 2019-06-13 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
FR3083088B1 (fr) 2018-06-29 2020-10-02 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
US11633460B2 (en) 2017-12-07 2023-04-25 Adocia Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals
CA3084688A1 (fr) 2017-12-07 2019-06-13 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
EP4671300A2 (fr) 2017-12-07 2025-12-31 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
US20210214412A1 (en) * 2018-04-16 2021-07-15 University Of Utah Research Foundation Glucose-responsive insulin
WO2019243628A1 (fr) 2018-06-22 2019-12-26 Adocia Composition injectable a ph 7 comprenant un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes et au moins une insuline basale presentant au moins un effet prandial et un effet basal
FR3084585B1 (fr) 2018-08-03 2020-11-06 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un compose amphiphile porteur de radicaux hydrophobes
KR102666154B1 (ko) 2018-08-08 2024-05-20 주식회사 대웅제약 지속형 인슐린 아날로그 및 그 복합체
WO2020115334A1 (fr) 2018-12-07 2020-06-11 Adocia Procede de preparation d'une composition stable sous forme d'une solution aqueuse injectable
US20200179489A1 (en) 2018-12-07 2020-06-11 Adocia Injectable solution at ph 7 comprising at least one basal insulin which pi is from 5.8 to 8.5 and a co-polyamino-acid bearing carboxylate charges and hydrophobic radicals and a limited amount of m-cresol
KR20200080747A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 인슐린 전구체의 인슐린 효소 전환용 조성물 및 이를 이용하여 인슐린 전구체를 인슐린으로 전환하는 방법
KR20200080748A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법
KR20200082618A (ko) 2018-12-31 2020-07-08 주식회사 폴루스 인슐린 과발현용 램프 태그 및 이를 이용한 인슐린의 제조방법
WO2020245470A1 (fr) 2019-06-07 2020-12-10 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5, du liraglutide et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
TWI844709B (zh) 2019-07-31 2024-06-11 美商美國禮來大藥廠 鬆弛素(relaxin)類似物及其使用方法
CN113105536B (zh) 2020-09-11 2023-07-18 美药星（南京）制药有限公司 一种新甘精胰岛素原及其制备甘精胰岛素的方法
CN114805610B (zh) * 2022-06-23 2022-10-04 北京惠之衡生物科技有限公司 一种高表达甘精胰岛素前体的重组基因工程菌及其构建方法

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NO894424L (no) 1990-05-09
NZ231272A (en) 1992-11-25
ATE93868T1 (de) 1993-09-15
DE3837825A1 (de) 1990-05-10
AU4441289A (en) 1990-05-17
HU210800A9 (en) 1995-07-28
DK554789D0 (da) 1989-11-07
KR900007435A (ko) 1990-06-01
DK554789A (da) 1990-05-09
HU213018B (en) 1997-01-28
NL300019I1 (nl) 2000-12-01
JP2680145B2 (ja) 1997-11-19
US5656722A (en) 1997-08-12
IE893576L (en) 1990-05-08
HUT52549A (en) 1990-07-28
ZA898456B (en) 1990-06-27
LU90614I2 (fr) 2000-09-26
EP0368187A2 (fr) 1990-05-16
PT92220A (pt) 1990-05-31
PH30695A (en) 1997-09-16
EP0368187B1 (fr) 1993-09-01
PT92220B (pt) 1995-07-06
ES2059676T4 (es) 2012-03-13
US6100376A (en) 2000-08-08
IE63338B1 (en) 1995-04-19
FI100185B (fi) 1997-10-15
DK173196B1 (da) 2000-03-13
NO894424D0 (no) 1989-11-07
IL92222A (en) 1999-09-22
IL92222A0 (en) 1990-07-26
CA1339044C (fr) 1997-04-01
DE58905456D1 (de) 1993-10-07
ES2059676T3 (es) 1994-11-16
DE10075022I2 (de) 2002-07-04
NL300019I2 (nl) 2001-02-01
KR0158197B1 (ko) 1998-12-01
NO177963B (no) 1995-09-18
HU895678D0 (en) 1990-01-28
EP0368187A3 (fr) 1991-07-03
HK1006171A1 (en) 1999-02-12
DE10075022I1 (de) 2000-10-05
NO2001023I1 (no) 2001-12-17
FI895259A0 (fi) 1989-11-06
AU621680B2 (en) 1992-03-19
JPH02218696A (ja) 1990-08-31

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