NO176275C - Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazinonderivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazinonderivater

Info

Publication number: NO176275C
Authority: NO; Norway
Prior art keywords: preparation; therapeutically active; analogous process; pyridazinone derivatives; active pyridazinone
Prior art date: 1988-02-13

Application number

NO894088A

Other languages

English (en)

Other versions

NO894088L (no

NO894088D0 (no

NO176275B (no

Inventor

You Kusase

Masatoshi Murakata

Nobuo Mochizuki

Michinori Takebayashi

Original Assignee

Nippon Soda Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-13

Filing date

1989-10-12

Publication date

1995-03-08

1989-10-12 Application filed by Nippon Soda Co filed Critical Nippon Soda Co

1989-10-12 Publication of NO894088L publication Critical patent/NO894088L/no

1989-10-12 Publication of NO894088D0 publication Critical patent/NO894088D0/no

1994-11-28 Publication of NO176275B publication Critical patent/NO176275B/no

1995-03-08 Publication of NO176275C publication Critical patent/NO176275C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/36—Benzo-cinnolines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO894088A 1988-02-13 1989-10-12 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazinonderivater NO176275C (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP3161888		1988-02-13
JP7591088		1988-03-31
PCT/JP1989/000127 WO1989007594A1 (en)	1988-02-13	1989-02-09	Pyridazinone derivatives

Publications (4)

Publication Number	Publication Date
NO894088L NO894088L (no)	1989-10-12
NO894088D0 NO894088D0 (no)	1989-10-12
NO176275B NO176275B (no)	1994-11-28
NO176275C true NO176275C (no)	1995-03-08

Family

ID=26370117

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO894088A NO176275C (no)	1988-02-13	1989-10-12	Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazinonderivater

Country Status (11)

Country	Link
US (1)	US5110925A (no)
EP (1)	EP0357788B1 (no)
JP (1)	JP2717687B2 (no)
KR (1)	KR910005233B1 (no)
CA (1)	CA1320957C (no)
DE (1)	DE68910447T2 (no)
DK (1)	DK170096B1 (no)
ES (1)	ES2012646A6 (no)
FI (1)	FI95570C (no)
NO (1)	NO176275C (no)
WO (1)	WO1989007594A1 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8903130D0 (en) *	1989-02-11	1989-03-30	Orion Yhtymae Oy	Substituted pyridazinones
JP2806192B2 (ja) *	1992-11-02	1998-09-30	日本曹達株式会社	血小板凝集抑制剤
US5678114A (en) *	1994-06-14	1997-10-14	Noritsu Koki Co., Ltd.	Automatic photographic developing apparatus for photosensitive materials
CA2204915A1 (en) *	1994-11-11	1996-05-23	Seiichi Uchida	Optically active compound
CA2265495A1 (en) *	1996-09-13	1998-03-19	The Board Of Trustees Of The Leland Stanford Junior University	Non-hormonal method of contraception
WO2000021935A1 (en) *	1998-10-09	2000-04-20	Nihon Nohyaku Co., Ltd.	Pyridazinone derivatives
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
EP2218442A1 (en)	2005-11-09	2010-08-18	CombinatoRx, Inc.	Methods, compositions, and kits for the treatment of ophthalmic disorders
WO2008151257A2 (en)	2007-06-04	2008-12-11	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009149279A2 (en)	2008-06-04	2009-12-10	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en)	2008-07-16	2019-09-24	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
KR102034748B1 (ko)	2011-03-01	2019-10-21	시너지 파마슈티컬즈 인코포레이티드	구아닐레이트 사이클라제 c 작용제의 제조 방법
EP2804603A1 (en)	2012-01-10	2014-11-26	President and Fellows of Harvard College	Beta-cell replication promoting compounds and methods of their use
US9545446B2 (en)	2013-02-25	2017-01-17	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
EP2970384A1 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
WO2014151200A2 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
AU2014274812B2 (en)	2013-06-05	2018-09-27	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2015021358A2 (en)	2013-08-09	2015-02-12	Dominique Charmot	Compounds and methods for inhibiting phosphate transport
US9884806B2 (en)	2013-08-30	2018-02-06	Icahn School Of Medicine At Mount Sinai	Cyclic vinylogous amides as bromodomain inhibitors
CN114340631A (zh)	2019-05-21	2022-04-12	阿德利克斯股份有限公司	用于降低患者的血清磷酸盐的组合

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4019575A (en) *	1975-12-22	1977-04-26	Chevron Research Company	System for recovering viscous petroleum from thick tar sand
JPS5746966A (en) *	1980-09-03	1982-03-17	Mitsui Toatsu Chem Inc	Pyridazinone derivative and its production
US4665174A (en) *	1981-05-12	1987-05-12	Sumitomo Chemical Company, Limited	Production of cyclopentenone derivatives
JPS58113180A (ja) *	1981-12-28	1983-07-05	Mitsui Toatsu Chem Inc	ピリダジノン誘導体
DE3302442A1 (de) *	1983-01-26	1984-07-26	Basf Ag, 6700 Ludwigshafen	Neue pyridazinone, verfahren zu ihrer herstellung, diese verbindungen enthaltende therapeutische mittel und deren verwendung
US4602019A (en) *	1983-04-22	1986-07-22	Warner-Lambert Company	Indeno[1,2-c]pyridazin-3-one derivatives useful as cardiotonic and antihypertensive agents
US4666902A (en) *	1983-06-20	1987-05-19	Cassella Aktiengesellschaft	Tetrahydropyridazinone derivatives, processes for their preparation and their use
GB2164643B (en) *	1984-07-27	1988-11-02	Boehringer Biochemia Srl	Tricyclic dihydropyridazinones and pharmaceutical compositions containing them
JPH06763B2 (ja) *	1984-08-28	1994-01-05	吉富製薬株式会社	ベンゾ〔ｈ〕シンノリン誘導体
US4816454A (en) *	1984-09-21	1989-03-28	Cassella Aktiengesellschaft	4,5-dihydro-3(2H)-pyridazinones and their pharmacological use
US4681621A (en) *	1984-12-20	1987-07-21	Stauffer Chemical Company	Herbicidal 2-(2-substituted benzoyl)-1,3-cyclopentanediones
DE3505609A1 (de) *	1985-02-19	1986-08-21	Merck Patent Gmbh, 6100 Darmstadt	Benzimidazolyl-pyridazinone
GB2177689B (en) *	1985-07-09	1989-07-19	Boehringer Biochemia Srl	Tricyclic dihydropyridazinones and pharmaceutical compositions containing them
JPH0633277B2 (ja) *	1986-01-10	1994-05-02	吉富製薬株式会社	ベンゾチオピラノ〔４，３−ｃ〕ピリダジン化合物
US4775411A (en) *	1986-06-09	1988-10-04	Stauffer Chemica Company	Certain substituted 3-amino-2-benzoylcyclohex-2-enones
EP0281045B1 (en) *	1987-03-02	1991-12-27	Yoshitomi Pharmaceutical Industries, Ltd.	Benzothiepino (5,4-c) pyridazine compounds and their pharmaceutical uses
DE3804490A1 (de) *	1988-02-12	1989-08-24	Heumann Pharma Gmbh & Co	Substituierte 6-phenyldihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPH0216991A (ja) *	1988-07-04	1990-01-19	Mitsui Toatsu Chem Inc	Ｌ−トリプトファンの製法

1989
- 1989-01-31 JP JP1019514A patent/JP2717687B2/ja not_active Expired - Lifetime
- 1989-02-09 DE DE89902288T patent/DE68910447T2/de not_active Expired - Fee Related
- 1989-02-09 US US07/427,123 patent/US5110925A/en not_active Expired - Fee Related
- 1989-02-09 CA CA000590590A patent/CA1320957C/en not_active Expired - Fee Related
- 1989-02-09 WO PCT/JP1989/000127 patent/WO1989007594A1/en not_active Ceased
- 1989-02-09 KR KR1019890701882A patent/KR910005233B1/ko not_active Expired
- 1989-02-09 EP EP89902288A patent/EP0357788B1/en not_active Expired - Lifetime
- 1989-02-10 ES ES8900493A patent/ES2012646A6/es not_active Expired - Fee Related
- 1989-10-10 DK DK502389A patent/DK170096B1/da not_active IP Right Cessation
- 1989-10-12 FI FI894844A patent/FI95570C/fi not_active IP Right Cessation
- 1989-10-12 NO NO894088A patent/NO176275C/no unknown

Also Published As

Publication number	Publication date
FI894844A0 (fi)	1989-10-12
NO894088L (no)	1989-10-12
FI95570C (fi)	1996-02-26
FI95570B (fi)	1995-11-15
KR900700462A (ko)	1990-08-13
DK502389A (da)	1989-11-20
ES2012646A6 (es)	1990-04-01
NO894088D0 (no)	1989-10-12
WO1989007594A1 (en)	1989-08-24
JP2717687B2 (ja)	1998-02-18
NO176275B (no)	1994-11-28
DK170096B1 (da)	1995-05-22
EP0357788B1 (en)	1993-11-03
DK502389D0 (da)	1989-10-10
CA1320957C (en)	1993-08-03
EP0357788A1 (en)	1990-03-14
DE68910447T2 (de)	1994-03-17
DE68910447D1 (de)	1993-12-09
US5110925A (en)	1992-05-05
KR910005233B1 (ko)	1991-07-24
JPH0256468A (ja)	1990-02-26

Publication	Publication Date	Title
FI96861C (fi)	1996-09-10	Menetelmä terapeuttisesti aktiivisten substituoitujen indolyylipyrrolijohdannaisten valmistamiseksi
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NO176275C (no)	1995-03-08	Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazinonderivater
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NO174203C (no)	1994-04-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive
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NO169652C (no)	1992-07-22	Analogifremgangsmaate til fremstilling av terapeutisk aktive guaninderivater
NO176242C (no)	1995-03-01	Analogifremgangsmåte for fremstilling av terapeutisk aktive 5-substituerte ornithinderivater
NO304428B1 (no)	1998-12-14	AnalogifremgangsmÕte for fremstilling av terapeutisk aktive vinylazoler