NO174032C - Fremgangsmåte for fremstilling av en legemiddel-polymer-matriks innbefattende dimenhydrinat som en aktiv bestanddel - Google Patents
Fremgangsmåte for fremstilling av en legemiddel-polymer-matriks innbefattende dimenhydrinat som en aktiv bestanddelInfo
- Publication number
- NO174032C NO174032C NO863398A NO863398A NO174032C NO 174032 C NO174032 C NO 174032C NO 863398 A NO863398 A NO 863398A NO 863398 A NO863398 A NO 863398A NO 174032 C NO174032 C NO 174032C
- Authority
- NO
- Norway
- Prior art keywords
- active ingredient
- drug
- polymer matrix
- hydrinate
- dimene
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title abstract 3
- 239000011159 matrix material Substances 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title abstract 2
- NFLLKCVHYJRNRH-UHFFFAOYSA-N 8-chloro-1,3-dimethyl-7H-purine-2,6-dione 2-(diphenylmethyl)oxy-N,N-dimethylethanamine Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC(Cl)=N2.C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 NFLLKCVHYJRNRH-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- ZIKJCAPMXXTMDD-UHFFFAOYSA-M sodium;2-(1-hydroxycyclohexyl)butanoate Chemical compound [Na+].CCC(C([O-])=O)C1(O)CCCCC1 ZIKJCAPMXXTMDD-UHFFFAOYSA-M 0.000 title 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76898185A | 1985-08-26 | 1985-08-26 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO863398D0 NO863398D0 (no) | 1986-08-25 |
| NO863398L NO863398L (no) | 1987-02-27 |
| NO174032B NO174032B (no) | 1993-11-29 |
| NO174032C true NO174032C (no) | 1994-03-09 |
Family
ID=25084045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO863398A NO174032C (no) | 1985-08-26 | 1986-08-25 | Fremgangsmåte for fremstilling av en legemiddel-polymer-matriks innbefattende dimenhydrinat som en aktiv bestanddel |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0212641B1 (no) |
| JP (1) | JPH0816069B2 (no) |
| AT (1) | ATE62407T1 (no) |
| AU (1) | AU589991B2 (no) |
| CA (1) | CA1306949C (no) |
| DE (1) | DE3678640D1 (no) |
| DK (1) | DK404486A (no) |
| FI (1) | FI863435A7 (no) |
| GR (1) | GR862190B (no) |
| IE (1) | IE58832B1 (no) |
| IL (1) | IL79816A (no) |
| NO (1) | NO174032C (no) |
| NZ (1) | NZ217326A (no) |
| PH (1) | PH23378A (no) |
| PT (1) | PT83241B (no) |
| ZA (1) | ZA866427B (no) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4971791A (en) * | 1985-08-26 | 1990-11-20 | The Procter & Gamble Company | Taste masking compositions |
| US4760093A (en) * | 1986-10-21 | 1988-07-26 | American Home Products Corporation (Del.) | Spray dried acetaminophen |
| US4851226A (en) * | 1987-11-16 | 1989-07-25 | Mcneil Consumer Products Company | Chewable medicament tablet containing means for taste masking |
| JP2687401B2 (ja) * | 1988-03-22 | 1997-12-08 | 藤沢薬品工業株式会社 | 内服用懸濁剤 |
| HU208495B (en) * | 1990-06-27 | 1993-11-29 | Alkaloida Vegyeszeti Gyar | Process for producing retarde pharmaceutical compositions |
| EP0572731A1 (en) * | 1992-06-01 | 1993-12-08 | The Procter & Gamble Company | Chewable preparation containing a decongestant |
| JPH0710747A (ja) * | 1993-04-28 | 1995-01-13 | Takeda Chem Ind Ltd | 固形製剤およびその製造方法 |
| DE69419281T2 (de) * | 1993-04-28 | 2000-03-23 | Takeda Chemical Industries, Ltd. | Geschmacksmaskierte feste Zubereitung und Verfahren zur Herstellung |
| IT1274241B (it) * | 1993-12-03 | 1997-07-15 | Smithkline Beecham Farma | Complessi agente terapeutico/matrice polimerica dotati di migliorate caratteristiche di sapore e composizioni farmaceutiche che li contengono |
| DE19631084A1 (de) * | 1996-08-01 | 1998-02-05 | Basf Ag | Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut |
| US6638948B1 (en) * | 1996-09-09 | 2003-10-28 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
| DE59712198D1 (de) * | 1997-07-10 | 2005-03-17 | Gergely Dr & Co | Lösliche, gummihaltige, dragierte Kautablette |
| JP3143433B2 (ja) * | 1998-07-07 | 2001-03-07 | 三基商事株式会社 | マスキング組成物 |
| WO2000016742A1 (en) * | 1998-09-24 | 2000-03-30 | The Procter & Gamble Company | Chewable compositions containing dextromethorphan |
| CN111904924A (zh) * | 2013-11-13 | 2020-11-10 | 财团法人国际教育基金会 | 化合物降低对乙酰氨基酚引起的肝毒性的用途及复方组合 |
| JP6858729B2 (ja) * | 2018-05-25 | 2021-04-14 | ▲財▼▲団▼法人国防教育研究基金会National Defense Education And Research Foundation | 肝臓に対する副作用がない、新しいアセトアミノフェン複合組成 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2993837A (en) * | 1959-07-13 | 1961-07-25 | Frosst & Co Charles E | Enteric coated tablets |
| US3594470A (en) * | 1968-02-19 | 1971-07-20 | Abbott Lab | Chewable tablets including coated particles of pseudoephedrine-weak cation exchange resin |
| USRE28316E (en) * | 1968-09-03 | 1975-01-21 | Entrapment compositions and processes | |
| ZA718014B (en) * | 1970-12-23 | 1972-08-30 | Beecham Group Ltd | Pharmaceutical formulations |
| JPS5179716A (en) * | 1974-12-28 | 1976-07-12 | Shinetsu Chemical Co | Kokeiiyakuseizaino seizohoho |
-
1986
- 1986-08-22 CA CA000516619A patent/CA1306949C/en not_active Expired - Lifetime
- 1986-08-22 DE DE8686111636T patent/DE3678640D1/de not_active Expired - Lifetime
- 1986-08-22 IL IL79816A patent/IL79816A/xx not_active IP Right Cessation
- 1986-08-22 PT PT83241A patent/PT83241B/pt not_active IP Right Cessation
- 1986-08-22 EP EP86111636A patent/EP0212641B1/en not_active Expired - Lifetime
- 1986-08-22 AU AU61680/86A patent/AU589991B2/en not_active Ceased
- 1986-08-22 PH PH34175A patent/PH23378A/en unknown
- 1986-08-22 NZ NZ217326A patent/NZ217326A/xx unknown
- 1986-08-22 AT AT86111636T patent/ATE62407T1/de not_active IP Right Cessation
- 1986-08-25 ZA ZA866427A patent/ZA866427B/xx unknown
- 1986-08-25 NO NO863398A patent/NO174032C/no unknown
- 1986-08-25 FI FI863435A patent/FI863435A7/fi not_active Application Discontinuation
- 1986-08-25 DK DK404486A patent/DK404486A/da not_active Application Discontinuation
- 1986-08-25 JP JP61198790A patent/JPH0816069B2/ja not_active Expired - Lifetime
- 1986-08-25 IE IE226786A patent/IE58832B1/en not_active IP Right Cessation
- 1986-08-25 GR GR862190A patent/GR862190B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3678640D1 (de) | 1991-05-16 |
| IL79816A (en) | 1990-11-05 |
| PT83241B (pt) | 1988-07-01 |
| EP0212641A3 (en) | 1988-03-09 |
| GR862190B (en) | 1986-12-23 |
| IL79816A0 (en) | 1986-11-30 |
| PH23378A (en) | 1989-07-26 |
| JPH0816069B2 (ja) | 1996-02-21 |
| IE862267L (en) | 1987-02-26 |
| AU589991B2 (en) | 1989-10-26 |
| DK404486A (da) | 1987-02-27 |
| ZA866427B (en) | 1987-10-28 |
| NZ217326A (en) | 1990-02-26 |
| PT83241A (en) | 1986-09-01 |
| FI863435L (fi) | 1987-02-27 |
| IE58832B1 (en) | 1993-11-17 |
| NO863398D0 (no) | 1986-08-25 |
| FI863435A7 (fi) | 1987-02-27 |
| AU6168086A (en) | 1987-03-05 |
| ATE62407T1 (de) | 1991-04-15 |
| NO863398L (no) | 1987-02-27 |
| FI863435A0 (fi) | 1986-08-25 |
| DK404486D0 (da) | 1986-08-25 |
| CA1306949C (en) | 1992-09-01 |
| EP0212641A2 (en) | 1987-03-04 |
| EP0212641B1 (en) | 1991-04-10 |
| NO174032B (no) | 1993-11-29 |
| JPS6251627A (ja) | 1987-03-06 |
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