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NL980041I2 - 1H-imidazoÄ4,5-cÜchinoline en 1H-imidazoÄ4,5-cÜchinoline-4-aminen. - Google Patents

1H-imidazoÄ4,5-cÜchinoline en 1H-imidazoÄ4,5-cÜchinoline-4-aminen.

Info

Publication number
NL980041I2
NL980041I2 NL980041C NL980041C NL980041I2 NL 980041 I2 NL980041 I2 NL 980041I2 NL 980041 C NL980041 C NL 980041C NL 980041 C NL980041 C NL 980041C NL 980041 I2 NL980041 I2 NL 980041I2
Authority
NL
Netherlands
Prior art keywords
imidazo
cuquinoline
carbon atoms
group
amines
Prior art date
Application number
NL980041C
Other languages
English (en)
Other versions
NL980041I1 (nl
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of NL980041I1 publication Critical patent/NL980041I1/nl
Publication of NL980041I2 publication Critical patent/NL980041I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Physical Water Treatments (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Quinoline Compounds (AREA)
  • Alarm Systems (AREA)
  • Lubricants (AREA)
  • Luminescent Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
NL980041C 1983-11-18 1998-12-14 1H-imidazoÄ4,5-cÜchinoline en 1H-imidazoÄ4,5-cÜchinoline-4-aminen. NL980041I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55315883A 1983-11-18 1983-11-18
US55315783A 1983-11-18 1983-11-18

Publications (2)

Publication Number Publication Date
NL980041I1 NL980041I1 (nl) 1999-02-01
NL980041I2 true NL980041I2 (nl) 1999-07-01

Family

ID=27070262

Family Applications (2)

Application Number Title Priority Date Filing Date
NL980041C NL980041I2 (nl) 1983-11-18 1998-12-14 1H-imidazoÄ4,5-cÜchinoline en 1H-imidazoÄ4,5-cÜchinoline-4-aminen.
NL980043C NL980043I1 (nl) 1983-11-18 1998-12-14 Chinoline-tussenprodukten voor de synthese van 1H-imidazoc4,5-c!chinolines en 1H-imidazoc4,5-c!chinoline-4-amine.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL980043C NL980043I1 (nl) 1983-11-18 1998-12-14 Chinoline-tussenprodukten voor de synthese van 1H-imidazoc4,5-c!chinolines en 1H-imidazoc4,5-c!chinoline-4-amine.

Country Status (15)

Country Link
EP (2) EP0145340B1 (nl)
JP (1) JPS60123488A (nl)
KR (1) KR900005657B1 (nl)
AT (2) ATE84525T1 (nl)
AU (2) AU581190B2 (nl)
CA (1) CA1271477A (nl)
DE (3) DE19975027I2 (nl)
DK (6) DK164280C (nl)
ES (1) ES8603477A1 (nl)
IE (1) IE57874B1 (nl)
IL (2) IL84537A (nl)
NL (2) NL980041I2 (nl)
NO (7) NO163819C (nl)
NZ (1) NZ210228A (nl)
PH (1) PH22338A (nl)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
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CA1306260C (en) * 1985-10-18 1992-08-11 Shionogi & Co., Ltd. Condensed imidazopyridine derivatives
US4942168A (en) * 1987-07-13 1990-07-17 Hoechst-Roussel Pharmaceuticals Inc. Hydroxyquinoline amines, and method of enhancing memory in mammals
CA1335996C (en) * 1988-02-16 1995-06-20 Susumu Takada 2-substituted carbonylimidazo¬4,5-c|quinolines
US5019574A (en) * 1988-09-30 1991-05-28 Chugai Seiyaku Kabushiki Kaisha 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function
DE69029212T2 (de) * 1989-02-27 1997-05-22 Riker Laboratories Inc 4-Amino-1H-Imidazo(4,5-c)chinoline als antivirale Mittel
CA2011504C (en) * 1989-03-07 1998-06-02 Kenji Ohmori Imidazoquinolone derivatives
US4929624A (en) * 1989-03-23 1990-05-29 Minnesota Mining And Manufacturing Company Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
JP2988692B2 (ja) * 1989-07-18 1999-12-13 協和醗酵工業株式会社 イミダゾキノロン誘導体
US4988815A (en) * 1989-10-26 1991-01-29 Riker Laboratories, Inc. 3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines
FR2654021B1 (fr) * 1989-11-07 1992-02-28 Simond Jacques Procede de vitrification de cendres volantes et dispositif pour sa mise en óoeuvre.
GB8928281D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds
DK0459505T3 (da) * 1990-06-01 1996-11-18 Kyowa Hakko Kogyo Kk Imidazonaphthyridinderivater
HU222251B1 (hu) * 1991-03-01 2003-05-28 Minnesota Mining And Manufacturing Company 1-és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-amin-származékok előállításában alkalmazható 1- és 2-helyzetben szubsztituált 1H-imidazo[4,5-c]kinolin-4-(szubsztituált)-származékok
US5266575A (en) * 1991-11-06 1993-11-30 Minnesota Mining And Manufacturing Company 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
IL105325A (en) * 1992-04-16 1996-11-14 Minnesota Mining & Mfg Immunogen/vaccine adjuvant composition
US5395937A (en) * 1993-01-29 1995-03-07 Minnesota Mining And Manufacturing Company Process for preparing quinoline amines
US5693811A (en) * 1996-06-21 1997-12-02 Minnesota Mining And Manufacturing Company Process for preparing tetrahdroimidazoquinolinamines
US6069149A (en) * 1997-01-09 2000-05-30 Terumo Kabushiki Kaisha Amide derivatives and intermediates for the synthesis thereof
JPH10298181A (ja) * 1997-04-25 1998-11-10 Sumitomo Pharmaceut Co Ltd タイプ２ヘルパーｔ細胞選択的免疫応答抑制剤
JP2000119271A (ja) 1998-08-12 2000-04-25 Hokuriku Seiyaku Co Ltd １ｈ―イミダゾピリジン誘導体
UA74852C2 (en) * 2000-12-08 2006-02-15 3M Innovative Properties Co Urea-substituted imidazoquinoline ethers
CA2463101A1 (en) * 2001-10-23 2003-05-01 Applied Research Systems Ars Holding N.V. Azole derivatives and pharmaceutical compositions containing them
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IL166307A0 (en) 2002-07-26 2006-01-15 Preparation of 1h-imidazoÄ4,5-cÜquinolin-4-amines via novel 1h-imidazoÄ4,5-cÜquinolin-4-cyano and 1h-imidazo Ä4,5-cÜquinolin-4-cyano and 1h-imidazoÄ4,5-cÜquinolin-4-carboxamide intermediates
TW200510412A (en) 2003-08-12 2005-03-16 3M Innovative Properties Co Oxime substituted imidazo-containing compounds
AR045529A1 (es) * 2003-08-27 2005-11-02 3M Innovative Properties Co Imidazoquinolinas sustituidas con grupos ariloxi o arilalquilenoxi
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US7687628B2 (en) 2003-10-01 2010-03-30 Taro Pharmaceuticals U.S.A., Inc. Method of preparing 4-amino-1H-imidazo(4,5-c)quinolines and acid addition salts thereof
WO2005032484A2 (en) 2003-10-03 2005-04-14 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
ITMI20032121A1 (it) * 2003-11-04 2005-05-05 Dinamite Dipharma Spa In Forma Abbr Eviata Dipharm Procedimento per la preparazione di imiquimod e suoi intermedi
JP2007511527A (ja) 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー オキシム置換イミダゾ環化合物
EP1682544A4 (en) 2003-11-14 2009-05-06 3M Innovative Properties Co HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS
AU2004293078B2 (en) 2003-11-25 2012-01-19 3M Innovative Properties Company Substituted imidazo ring systems and methods
US8802853B2 (en) 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
EP1699788A2 (en) 2003-12-30 2006-09-13 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl and imidazonaphthyridinyl sulfonamides
EP1730143A2 (en) 2004-03-24 2006-12-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
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WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
AU2005322898B2 (en) 2004-12-30 2011-11-24 3M Innovative Properties Company Chiral fused (1,2)imidazo(4,5-c) ring compounds
WO2006083440A2 (en) 2004-12-30 2006-08-10 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
WO2006084251A2 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
US7968563B2 (en) 2005-02-11 2011-06-28 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
CA2602590A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
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JP2009504803A (ja) 2005-08-22 2009-02-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Ｔｌｒアゴニスト
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EP2009002A1 (en) * 2007-06-21 2008-12-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) New process for the manufacture of 1H-imidazo [4,5-c]-quinoline ring systems
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US8728486B2 (en) 2011-05-18 2014-05-20 University Of Kansas Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds
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CN106943596A (zh) 2016-01-07 2017-07-14 博笛生物科技（北京）有限公司 用于治疗肿瘤的抗-cd20组合
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US11697851B2 (en) 2016-05-24 2023-07-11 The Regents Of The University Of California Early ovarian cancer detection diagnostic test based on mRNA isoforms
TWI674261B (zh) 2017-02-17 2019-10-11 美商英能腫瘤免疫股份有限公司 Nlrp3 調節劑
CN108794467A (zh) 2017-04-27 2018-11-13 博笛生物科技有限公司 2-氨基-喹啉衍生物
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FR3113287B1 (fr) 2020-08-07 2023-06-23 Phv Pharma Procédé industriel de synthèse de l’imiquimod à partir de la quinolèine-2,4-diol applicable à son utilisation pharmaceutique
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US3700674A (en) * 1969-04-30 1972-10-24 American Cyanamid Co 4-alkylamino-3-nitroquinolines
IL68495A0 (en) * 1982-05-03 1983-07-31 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines

Also Published As

Publication number Publication date
DK164451B (da) 1992-06-29
DK164455B (da) 1992-06-29
DK164455C (da) 1992-11-16
ES537677A0 (es) 1985-12-16
DK164452C (da) 1992-11-09
DK136191D0 (da) 1991-07-16
AU2991189A (en) 1989-06-15
NO890826L (no) 1985-05-20
DK164452B (da) 1992-06-29
NO163819B (no) 1990-04-17
NO169437C (no) 1992-06-24
DK542684D0 (da) 1984-11-15
AU581190B2 (en) 1989-02-16
AU611997B2 (en) 1991-06-27
KR900005657B1 (ko) 1990-08-03
NO165147C (no) 1991-01-02
ATE49763T1 (de) 1990-02-15
DE3486043D1 (de) 1993-02-25
NO163819C (no) 1990-08-01
EP0145340A2 (en) 1985-06-19
IL84537A0 (en) 1988-04-29
NO890825D0 (no) 1989-02-27
DK135791A (da) 1991-07-16
DK136191A (da) 1991-07-16
DK136091A (da) 1991-07-16
NO165145C (no) 1991-01-02
JPS60123488A (ja) 1985-07-02
NZ210228A (en) 1989-01-27
NO165146C (no) 1991-01-02
EP0145340B1 (en) 1990-01-24
NO165147B (no) 1990-09-24
NO890825L (no) 1985-05-20
NO165146B (no) 1990-09-24
DK542684A (da) 1985-05-19
DK135991A (da) 1991-07-16
JPH0586391B2 (nl) 1993-12-10
ATE84525T1 (de) 1993-01-15
IE842952L (en) 1985-05-18
NO890823D0 (no) 1989-02-27
NO169437B (no) 1992-03-16
DE3486043T2 (de) 1993-06-03
AU3540284A (en) 1985-05-23
DK165921C (da) 1993-06-28
DE3481124D1 (de) 1990-03-01
EP0145340A3 (en) 1986-06-11
EP0310950A1 (en) 1989-04-12
NO165145B (no) 1990-09-24
NL980041I1 (nl) 1999-02-01
DE19975027I2 (de) 2000-09-21
DK135791D0 (da) 1991-07-16
DK135891A (da) 1991-07-16
NO890822L (no) 1985-05-20
EP0310950B1 (en) 1993-01-13
NO168705B (no) 1991-12-16
DK164280B (da) 1992-06-01
NO890826D0 (no) 1989-02-27
NO168705C (no) 1992-03-25
NO844565L (no) 1985-05-20
NO890822D0 (no) 1989-02-27
NO1999015I1 (no) 1999-07-08
DK164280C (da) 1992-11-30
NO890824D0 (no) 1989-02-27
ES8603477A1 (es) 1985-12-16
NL980043I1 (nl) 1999-02-01
DK136091D0 (da) 1991-07-16
CA1271477A (en) 1990-07-10
NO890823L (no) 1985-05-20
DK169179B1 (da) 1994-09-05
DK165921B (da) 1993-02-08
PH22338A (en) 1988-08-12
DK135991D0 (da) 1991-07-16
KR850003890A (ko) 1985-06-29
NO890824L (no) 1985-05-20
DK164451C (da) 1992-11-09
IL84537A (en) 1990-12-23
DK135891D0 (da) 1991-07-16
IE57874B1 (en) 1993-05-05

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