NL930021I2 - Process for the preparation of pharmaceutical preparations with anti-inflammatory, analgesic, antipyretic and smooth muscle relaxing effect, the pharmaceutical preparations thus obtained, and a process for the preparation of compounds with said effects. - Google Patents

Process for the preparation of pharmaceutical preparations with anti-inflammatory, analgesic, antipyretic and smooth muscle relaxing effect, the pharmaceutical preparations thus obtained, and a process for the preparation of compounds with said effects.

Info

Publication number: NL930021I2
Authority: NL; Netherlands
Prior art keywords: preparation; pharmaceutical preparations; antipyretic; analgesic; inflammatory
Prior art date: 1976-07-14

Application number

NL930021C

Other languages

Dutch (nl)

Other versions

NL930021I1 (en

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-14

Filing date

1993-03-23

Publication date

1997-03-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL930021(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1977-02-23 Priority claimed from US05/771,286 external-priority patent/US4089969A/en

1993-03-23 Application filed by Syntex Inc filed Critical Syntex Inc

1993-05-03 Publication of NL930021I1 publication Critical patent/NL930021I1/en

1997-03-03 Publication of NL930021I2 publication Critical patent/NL930021I2/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)

NL930021C 1976-07-14 1993-03-23 Process for the preparation of pharmaceutical preparations with anti-inflammatory, analgesic, antipyretic and smooth muscle relaxing effect, the pharmaceutical preparations thus obtained, and a process for the preparation of compounds with said effects. NL930021I2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US70490976A	1976-07-14	1976-07-14
US05/771,286 US4089969A (en)	1976-07-14	1977-02-23	5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (2)

Publication Number	Publication Date
NL930021I1 NL930021I1 (en)	1993-05-03
NL930021I2 true NL930021I2 (en)	1997-03-03

Family

ID=27107410

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7707651,A NL186318C (en)	1976-07-14	1977-07-08	PROCESS FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS WITH ANTI-INFLAMMATORY, ANALGETIC, ANTIPYRETIC AND SMOOTH MUSCLE-RELATING EFFECTS, THE PHARMACEUTICAL PREPARATIONS THAT HAVE BEEN PROTECTED THAN PROTECTED PROTECTION AGAINST THESE PREVENTIONAL OPERATIONS.
NL930021C NL930021I2 (en)	1976-07-14	1993-03-23	Process for the preparation of pharmaceutical preparations with anti-inflammatory, analgesic, antipyretic and smooth muscle relaxing effect, the pharmaceutical preparations thus obtained, and a process for the preparation of compounds with said effects.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7707651,A NL186318C (en)	1976-07-14	1977-07-08	PROCESS FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS WITH ANTI-INFLAMMATORY, ANALGETIC, ANTIPYRETIC AND SMOOTH MUSCLE-RELATING EFFECTS, THE PHARMACEUTICAL PREPARATIONS THAT HAVE BEEN PROTECTED THAN PROTECTED PROTECTION AGAINST THESE PREVENTIONAL OPERATIONS.

Country Status (27)

Country	Link
JP (1)	JPS539788A (en)
AR (1)	AR224997A1 (en)
CA (1)	CA1102809A (en)
CH (3)	CH641458A5 (en)
CS (1)	CS204954B2 (en)
DE (2)	DE2731678A1 (en)
DK (1)	DK151886C (en)
ES (2)	ES460706A1 (en)
FI (1)	FI63406C (en)
FR (2)	FR2358406A1 (en)
GB (1)	GB1554075A (en)
GR (1)	GR61111B (en)
HK (1)	HK15981A (en)
HU (1)	HU174224B (en)
IE (1)	IE45253B1 (en)
IL (2)	IL52493A (en)
IT (1)	IT1117313B (en)
MX (1)	MX163202B (en)
MY (1)	MY8100357A (en)
NL (2)	NL186318C (en)
NO (1)	NO147564C (en)
NZ (1)	NZ184610A (en)
PL (4)	PL124444B1 (en)
PT (1)	PT66780B (en)
SE (1)	SE434643B (en)
SU (1)	SU695558A3 (en)
YU (1)	YU40816B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4140698A (en) *	1977-07-25	1979-02-20	Syntex (Usa) Inc.	1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
JPS55124633A (en) *	1979-03-19	1980-09-25	Sohachi Takeuchi	Manufacturing method of tubular vessel
US4344943A (en) *	1980-06-09	1982-08-17	Syntex (U.S.A.) Inc.	6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) *	1980-11-21	1982-10-12	Syntex (U.S.A.) Inc.	Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4511724A (en) *	1982-06-10	1985-04-16	Merck & Co., Inc.	5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
JPS5910589A (en) *	1982-06-10	1984-01-20	メルク　エンド　カムパニー　インコーポレーテツド	Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4874871A (en) *	1987-03-25	1989-10-17	Syntex (U.S.A.) Inc.	Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
JPH0739418B2 (en) *	1987-09-10	1995-05-01	久光製薬株式会社	Novel 3-aroyl-6,7-dihydro-5H-pyrrolo [1,2-c] imidazole-7-carboxylic acid derivative
JP2649168B2 (en) *	1988-02-25	1997-09-03	久光製薬株式会社	Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo [1,2-a] pyrrole-1-carboxylic acid derivatives
IT1250691B (en) *	1991-07-22	1995-04-21	Giancarlo Santus	THERAPEUTIC COMPOSITIONS FOR INTRANASAL ADMINISTRATION INCLUDING KETOROLAC.
DK0612521T3 (en) *	1991-11-11	2000-01-17	Hisamitsu Pharmaceutical Co	Keterola cold hot cover
DE4300697C1 (en) *	1993-01-13	1994-05-19	Roemmers Sa	New 2-pyrrolidino-ethyl ester of ketorolac - useful as analgesic, antiinflammatory and antipyretic agent with low ulcerogenicity
US5622948A (en) *	1994-12-01	1997-04-22	Syntex (U.S.A.) Inc.	Pyrrole pyridazine and pyridazinone anti-inflammatory agents
JP2008210666A (en) *	2007-02-27	2008-09-11	Okamura Corp	Lighting system in merchandise display shelf
CA3202461A1 (en) *	2020-12-16	2022-06-23	Robert T. Streeper	Dicarboxylic acid esters for inducing an analgesic effect

1977
- 1977-05-17 JP JP5697777A patent/JPS539788A/en active Granted
- 1977-07-07 DK DK307577A patent/DK151886C/en active
- 1977-07-07 AR AR268356A patent/AR224997A1/en active
- 1977-07-07 GR GR53907A patent/GR61111B/en unknown
- 1977-07-08 CH CH850077A patent/CH641458A5/en not_active IP Right Cessation
- 1977-07-08 IE IE1423/77A patent/IE45253B1/en not_active IP Right Cessation
- 1977-07-08 IL IL52493A patent/IL52493A/en unknown
- 1977-07-08 NL NLAANVRAGE7707651,A patent/NL186318C/en not_active IP Right Cessation
- 1977-07-08 PT PT66780A patent/PT66780B/en unknown
- 1977-07-11 FR FR7721356A patent/FR2358406A1/en active Granted
- 1977-07-11 YU YU1721/77A patent/YU40816B/en unknown
- 1977-07-11 GB GB28919/77A patent/GB1554075A/en not_active Expired
- 1977-07-11 FI FI772153A patent/FI63406C/en not_active IP Right Cessation
- 1977-07-11 NZ NZ184610A patent/NZ184610A/en unknown
- 1977-07-12 CS CS774646A patent/CS204954B2/en unknown
- 1977-07-12 CA CA282,599A patent/CA1102809A/en not_active Expired
- 1977-07-13 PL PL1977227290A patent/PL124444B1/en unknown
- 1977-07-13 SU SU772501050A patent/SU695558A3/en active
- 1977-07-13 IT IT68630/77A patent/IT1117313B/en active Protection Beyond IP Right Term
- 1977-07-13 PL PL1977227289A patent/PL124711B1/en unknown
- 1977-07-13 PL PL1977227291A patent/PL124445B1/en unknown
- 1977-07-13 PL PL1977199603A patent/PL109390B1/en unknown
- 1977-07-13 SE SE7708141A patent/SE434643B/en not_active IP Right Cessation
- 1977-07-13 NO NO772494A patent/NO147564C/en unknown
- 1977-07-13 DE DE19772731678 patent/DE2731678A1/en active Granted
- 1977-07-13 DE DE2760330A patent/DE2760330C2/de not_active Expired
- 1977-07-13 ES ES460706A patent/ES460706A1/en not_active Expired
- 1977-07-14 HU HU77SI1582A patent/HU174224B/en unknown
- 1977-12-20 FR FR7738508A patent/FR2375234A1/en active Granted
1978
- 1978-05-24 ES ES470214A patent/ES470214A1/en not_active Expired
1979
- 1979-11-22 IL IL58779A patent/IL58779A0/en unknown
1981
- 1981-04-23 HK HK159/81A patent/HK15981A/en unknown
- 1981-12-30 MY MY357/81A patent/MY8100357A/en unknown
1984
- 1984-02-22 CH CH86684A patent/CH646973A5/en not_active IP Right Cessation
- 1984-02-22 CH CH86584A patent/CH646972A5/en not_active IP Right Cessation
1991
- 1991-07-05 MX MX9100104A patent/MX163202B/en unknown
1993
- 1993-03-23 NL NL930021C patent/NL930021I2/en unknown

Also Published As

Publication number	Publication date
ES460706A1 (en)	1978-12-01
CH646972A5 (en)	1984-12-28
CH641458A5 (en)	1984-02-29
GB1554075A (en)	1979-10-17
FI63406B (en)	1983-02-28
NL186318B (en)	1990-06-01
PT66780A (en)	1977-08-01
CA1102809A (en)	1981-06-09
CS204954B2 (en)	1981-04-30
YU40816B (en)	1986-06-30
IL58779A0 (en)	1980-02-29
FI63406C (en)	1983-06-10
NL930021I1 (en)	1993-05-03
NO147564B (en)	1983-01-24
NO772494L (en)	1978-01-17
IE45253L (en)	1978-01-14
CH646973A5 (en)	1984-12-28
IT1117313B (en)	1986-02-17
HU174224B (en)	1979-11-28
PT66780B (en)	1978-12-18
PL124444B1 (en)	1983-01-31
GR61111B (en)	1978-09-12
NZ184610A (en)	1979-03-28
PL124445B1 (en)	1983-01-31
IE45253B1 (en)	1982-07-14
AU513384B2 (en)	1980-11-27
FR2358406A1 (en)	1978-02-10
DE2731678C2 (en)	1989-06-08
NL186318C (en)	1990-11-01
MX163202B (en)	1992-02-20
IL52493A0 (en)	1977-10-31
YU172177A (en)	1983-09-30
SU695558A3 (en)	1979-10-30
PL109390B1 (en)	1980-05-31
DK151886C (en)	1988-06-06
IL52493A (en)	1982-02-28
NO147564C (en)	1983-05-18
PL199603A1 (en)	1978-04-24
HK15981A (en)	1981-05-01
AU2697577A (en)	1979-01-18
AR224997A1 (en)	1982-02-15
DK307577A (en)	1978-01-15
FR2375234B1 (en)	1980-11-07
FI772153A7 (en)	1978-01-15
FR2375234A1 (en)	1978-07-21
DE2760330C2 (en)	1989-06-15
NL7707651A (en)	1978-01-17
MY8100357A (en)	1981-12-31
JPS539788A (en)	1978-01-28
DK151886B (en)	1988-01-11
JPS6254109B2 (en)	1987-11-13
SE434643B (en)	1984-08-06
SE7708141L (en)	1978-01-15
DE2731678A1 (en)	1978-03-16
FR2358406B1 (en)	1981-04-17
ES470214A1 (en)	1979-09-16
PL124711B1 (en)	1983-02-28

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