NL1004939C2 - Gebruik van een Eriobotrya japonica extract, in het bijzonder in het gebied van de cosmetica, voor het stimuleren van de synthesen van glucosaminoglycanen. - Google Patents
Gebruik van een Eriobotrya japonica extract, in het bijzonder in het gebied van de cosmetica, voor het stimuleren van de synthesen van glucosaminoglycanen. Download PDFInfo
- Publication number
- NL1004939C2 NL1004939C2 NL1004939A NL1004939A NL1004939C2 NL 1004939 C2 NL1004939 C2 NL 1004939C2 NL 1004939 A NL1004939 A NL 1004939A NL 1004939 A NL1004939 A NL 1004939A NL 1004939 C2 NL1004939 C2 NL 1004939C2
- Authority
- NL
- Netherlands
- Prior art keywords
- extract
- synthesis
- skin
- use according
- eriobotrya japonica
- Prior art date
Links
- 239000000284 extract Substances 0.000 title claims description 83
- 230000015572 biosynthetic process Effects 0.000 title claims description 34
- 238000003786 synthesis reaction Methods 0.000 title claims description 31
- 244000061508 Eriobotrya japonica Species 0.000 title claims description 30
- 239000002537 cosmetic Substances 0.000 title claims description 29
- 235000009008 Eriobotrya japonica Nutrition 0.000 title claims description 15
- 229920002683 Glycosaminoglycan Polymers 0.000 claims description 43
- 210000003491 skin Anatomy 0.000 claims description 38
- 239000000203 mixture Substances 0.000 claims description 37
- 238000000034 method Methods 0.000 claims description 23
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 18
- 210000002950 fibroblast Anatomy 0.000 claims description 16
- 238000002360 preparation method Methods 0.000 claims description 13
- 238000011282 treatment Methods 0.000 claims description 13
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 claims description 11
- 230000000694 effects Effects 0.000 claims description 11
- 238000000605 extraction Methods 0.000 claims description 11
- 230000000638 stimulation Effects 0.000 claims description 11
- 239000002253 acid Substances 0.000 claims description 10
- 210000004027 cell Anatomy 0.000 claims description 9
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 8
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 229920002674 hyaluronan Polymers 0.000 claims description 8
- 229960003160 hyaluronic acid Drugs 0.000 claims description 8
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 8
- 210000004207 dermis Anatomy 0.000 claims description 7
- 239000001963 growth medium Substances 0.000 claims description 7
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 6
- 150000001412 amines Chemical class 0.000 claims description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- 230000006872 improvement Effects 0.000 claims description 6
- 210000004927 skin cell Anatomy 0.000 claims description 6
- 229930003231 vitamin Natural products 0.000 claims description 6
- 239000011782 vitamin Substances 0.000 claims description 6
- 235000013343 vitamin Nutrition 0.000 claims description 6
- 229940088594 vitamin Drugs 0.000 claims description 6
- MSWZFWKMSRAUBD-GASJEMHNSA-N 2-amino-2-deoxy-D-galactopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O MSWZFWKMSRAUBD-GASJEMHNSA-N 0.000 claims description 5
- 102000008186 Collagen Human genes 0.000 claims description 5
- 108010035532 Collagen Proteins 0.000 claims description 5
- 229920001436 collagen Polymers 0.000 claims description 5
- 229960002442 glucosamine Drugs 0.000 claims description 5
- MSWZFWKMSRAUBD-IVMDWMLBSA-N glucosamine group Chemical group OC1[C@H](N)[C@@H](O)[C@H](O)[C@H](O1)CO MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 claims description 5
- 230000036571 hydration Effects 0.000 claims description 5
- 238000006703 hydration reaction Methods 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- 230000037303 wrinkles Effects 0.000 claims description 5
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 4
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 4
- OHCQJHSOBUTRHG-KGGHGJDLSA-N FORSKOLIN Chemical compound O=C([C@@]12O)C[C@](C)(C=C)O[C@]1(C)[C@@H](OC(=O)C)[C@@H](O)[C@@H]1[C@]2(C)[C@@H](O)CCC1(C)C OHCQJHSOBUTRHG-KGGHGJDLSA-N 0.000 claims description 4
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 claims description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 4
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims description 4
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims description 4
- 150000002148 esters Chemical class 0.000 claims description 4
- 229960002591 hydroxyproline Drugs 0.000 claims description 4
- 239000002798 polar solvent Substances 0.000 claims description 4
- 229960002429 proline Drugs 0.000 claims description 4
- 230000004936 stimulating effect Effects 0.000 claims description 4
- 241000167550 Centella Species 0.000 claims description 3
- 229940099471 Phosphodiesterase inhibitor Drugs 0.000 claims description 3
- UDMBCSSLTHHNCD-KQYNXXCUSA-N adenosine 5'-monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 claims description 3
- 102000030621 adenylate cyclase Human genes 0.000 claims description 3
- 108060000200 adenylate cyclase Proteins 0.000 claims description 3
- 150000001298 alcohols Chemical class 0.000 claims description 3
- QCYLIQBVLZBPNK-UHFFFAOYSA-N asiaticoside A Natural products O1C(C(=O)C(C)C)=CC(C)C(C2(C(OC(C)=O)CC34C5)C)C1CC2(C)C3CCC(C1(C)C)C45CCC1OC1OCC(O)C(O)C1O QCYLIQBVLZBPNK-UHFFFAOYSA-N 0.000 claims description 3
- 230000015556 catabolic process Effects 0.000 claims description 3
- 238000006731 degradation reaction Methods 0.000 claims description 3
- 235000013399 edible fruits Nutrition 0.000 claims description 3
- -1 for example Chemical compound 0.000 claims description 3
- 230000000887 hydrating effect Effects 0.000 claims description 3
- 239000002571 phosphodiesterase inhibitor Substances 0.000 claims description 3
- 239000000080 wetting agent Substances 0.000 claims description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 2
- 235000021508 Coleus Nutrition 0.000 claims description 2
- 244000061182 Coleus blumei Species 0.000 claims description 2
- 241000195493 Cryptophyta Species 0.000 claims description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 2
- SUZLHDUTVMZSEV-UHFFFAOYSA-N Deoxycoleonol Natural products C12C(=O)CC(C)(C=C)OC2(C)C(OC(=O)C)C(O)C2C1(C)C(O)CCC2(C)C SUZLHDUTVMZSEV-UHFFFAOYSA-N 0.000 claims description 2
- 244000133098 Echinacea angustifolia Species 0.000 claims description 2
- 229940122858 Elastase inhibitor Drugs 0.000 claims description 2
- 229940122393 Hyaluronidase inhibitor Drugs 0.000 claims description 2
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims description 2
- 229930182821 L-proline Natural products 0.000 claims description 2
- BNMGUJRJUUDLHW-HCZMHFOYSA-N Madecassoside Chemical compound O([C@@H]1[C@@H](CO)O[C@H]([C@@H]([C@H]1O)O)OC[C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)[C@]12CC[C@H]([C@@H]([C@H]1C=1[C@@]([C@@]3(C[C@@H](O)[C@H]4[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]4(C)[C@H]3CC=1)C)(C)CC2)C)C)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O BNMGUJRJUUDLHW-HCZMHFOYSA-N 0.000 claims description 2
- BNMGUJRJUUDLHW-HLUHVYOBSA-N Madecassoside Natural products C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5[C@H](O)C[C@@]34C)[C@@H]2[C@H]1C)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O BNMGUJRJUUDLHW-HLUHVYOBSA-N 0.000 claims description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 claims description 2
- NCYCYZXNIZJOKI-OVSJKPMPSA-N Retinaldehyde Chemical compound O=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-OVSJKPMPSA-N 0.000 claims description 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims description 2
- 241000213914 Tephrosia <angiosperm> Species 0.000 claims description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 2
- 229930003268 Vitamin C Natural products 0.000 claims description 2
- 229930003427 Vitamin E Natural products 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 229960005070 ascorbic acid Drugs 0.000 claims description 2
- 235000010323 ascorbic acid Nutrition 0.000 claims description 2
- 239000011668 ascorbic acid Substances 0.000 claims description 2
- 229960001948 caffeine Drugs 0.000 claims description 2
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims description 2
- 229940106189 ceramide Drugs 0.000 claims description 2
- 150000001783 ceramides Chemical class 0.000 claims description 2
- OHCQJHSOBUTRHG-UHFFFAOYSA-N colforsin Natural products OC12C(=O)CC(C)(C=C)OC1(C)C(OC(=O)C)C(O)C1C2(C)C(O)CCC1(C)C OHCQJHSOBUTRHG-UHFFFAOYSA-N 0.000 claims description 2
- 229940126513 cyclase activator Drugs 0.000 claims description 2
- 230000007423 decrease Effects 0.000 claims description 2
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 claims description 2
- 235000014134 echinacea Nutrition 0.000 claims description 2
- 239000003602 elastase inhibitor Substances 0.000 claims description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 claims description 2
- 229940090813 madecassoside Drugs 0.000 claims description 2
- 239000011777 magnesium Substances 0.000 claims description 2
- 231100000065 noncytotoxic Toxicity 0.000 claims description 2
- 230000002020 noncytotoxic effect Effects 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 230000008569 process Effects 0.000 claims description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 2
- 235000020945 retinal Nutrition 0.000 claims description 2
- 239000011604 retinal Substances 0.000 claims description 2
- 150000004492 retinoid derivatives Chemical class 0.000 claims description 2
- 229960003471 retinol Drugs 0.000 claims description 2
- 235000020944 retinol Nutrition 0.000 claims description 2
- 239000011607 retinol Substances 0.000 claims description 2
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 claims description 2
- 235000019155 vitamin A Nutrition 0.000 claims description 2
- 239000011719 vitamin A Substances 0.000 claims description 2
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 claims description 2
- 235000019160 vitamin B3 Nutrition 0.000 claims description 2
- 239000011708 vitamin B3 Substances 0.000 claims description 2
- 235000019154 vitamin C Nutrition 0.000 claims description 2
- 239000011718 vitamin C Substances 0.000 claims description 2
- 235000019165 vitamin E Nutrition 0.000 claims description 2
- 239000011709 vitamin E Substances 0.000 claims description 2
- 229940046009 vitamin E Drugs 0.000 claims description 2
- 229940045997 vitamin a Drugs 0.000 claims description 2
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 2
- 230000002378 acidificating effect Effects 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 230000003020 moisturizing effect Effects 0.000 claims 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 claims 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 1
- 108010003272 Hyaluronate lyase Proteins 0.000 claims 1
- 102000001974 Hyaluronidases Human genes 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- 102000016387 Pancreatic elastase Human genes 0.000 claims 1
- 108010067372 Pancreatic elastase Proteins 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims 1
- 238000009499 grossing Methods 0.000 claims 1
- 229960002773 hyaluronidase Drugs 0.000 claims 1
- 229960003136 leucine Drugs 0.000 claims 1
- PRAUVHZJPXOEIF-AOLYGAPISA-N madecassic acid Chemical compound C1[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]2[C@H](O)C[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C PRAUVHZJPXOEIF-AOLYGAPISA-N 0.000 claims 1
- 229940011656 madecassic acid Drugs 0.000 claims 1
- BUWCHLVSSFQLPN-UHFFFAOYSA-N madecassic acid Natural products CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C5CCC34C)C(=O)O)C2C1C)C(=O)OC6OC(COC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7O)C(O)C(O)C6O BUWCHLVSSFQLPN-UHFFFAOYSA-N 0.000 claims 1
- 159000000003 magnesium salts Chemical class 0.000 claims 1
- 229930002330 retinoic acid Natural products 0.000 claims 1
- 229960001153 serine Drugs 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 229960000278 theophylline Drugs 0.000 claims 1
- 229960002898 threonine Drugs 0.000 claims 1
- 229960001727 tretinoin Drugs 0.000 claims 1
- 241000196324 Embryophyta Species 0.000 description 17
- 238000004519 manufacturing process Methods 0.000 description 11
- 102000016611 Proteoglycans Human genes 0.000 description 8
- 108010067787 Proteoglycans Proteins 0.000 description 8
- 210000004209 hair Anatomy 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 239000002904 solvent Substances 0.000 description 7
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 239000000499 gel Substances 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 4
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 4
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 4
- 210000002744 extracellular matrix Anatomy 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 241001092070 Eriobotrya Species 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 210000002615 epidermis Anatomy 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 3
- 239000006210 lotion Substances 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000010992 reflux Methods 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 229920002971 Heparan sulfate Polymers 0.000 description 2
- 108010059712 Pronase Proteins 0.000 description 2
- 235000004789 Rosa xanthina Nutrition 0.000 description 2
- 241000220222 Rosaceae Species 0.000 description 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000002921 anti-spasmodic effect Effects 0.000 description 2
- 230000003833 cell viability Effects 0.000 description 2
- 238000005352 clarification Methods 0.000 description 2
- 125000000600 disaccharide group Chemical group 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000002500 effect on skin Effects 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 210000003780 hair follicle Anatomy 0.000 description 2
- 230000003779 hair growth Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 239000002304 perfume Substances 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000013049 sediment Substances 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 229940058015 1,3-butylene glycol Drugs 0.000 description 1
- MGGVALXERJRIRO-UHFFFAOYSA-N 4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]-2-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-1H-pyrazol-5-one Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C=1C(=NN(C=1)CC(=O)N1CC2=C(CC1)NN=N2)O MGGVALXERJRIRO-UHFFFAOYSA-N 0.000 description 1
- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- WYQVAPGDARQUBT-FGWHUCSPSA-N Madecassol Chemical compound O([C@@H]1[C@@H](CO)O[C@H]([C@@H]([C@H]1O)O)OC[C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)[C@]12CC[C@H]([C@@H]([C@H]1C=1[C@@]([C@@]3(CC[C@H]4[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]4(C)[C@H]3CC=1)C)(C)CC2)C)C)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O WYQVAPGDARQUBT-FGWHUCSPSA-N 0.000 description 1
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 description 1
- 240000004371 Panax ginseng Species 0.000 description 1
- 235000002789 Panax ginseng Nutrition 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- 244000184734 Pyrus japonica Species 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000012675 alcoholic extract Substances 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- WYQVAPGDARQUBT-XCWYDTOWSA-N asiaticoside Natural products O=C(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@H](O)[C@H](O)[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](CO)O2)O1)[C@@]12[C@@H]([C@@H](C)[C@H](C)CC1)C=1[C@](C)([C@@]3(C)[C@@H]([C@@]4(C)[C@H]([C@@](CO)(C)[C@@H](O)[C@H](O)C4)CC3)CC=1)CC2 WYQVAPGDARQUBT-XCWYDTOWSA-N 0.000 description 1
- 229940022757 asiaticoside Drugs 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 229960005261 aspartic acid Drugs 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- MSWZFWKMSRAUBD-QZABAPFNSA-N beta-D-glucosamine Chemical compound N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-QZABAPFNSA-N 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 229940007061 capsicum extract Drugs 0.000 description 1
- 239000001943 capsicum frutescens fruit extract Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000008278 cosmetic cream Substances 0.000 description 1
- 230000003013 cytotoxicity Effects 0.000 description 1
- 231100000135 cytotoxicity Toxicity 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
- 238000004299 exfoliation Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000003325 follicular Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 125000003827 glycol group Chemical group 0.000 description 1
- 230000031774 hair cycle Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- AEMOLEFTQBMNLQ-CLQWQSTFSA-N l-iduronic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O AEMOLEFTQBMNLQ-CLQWQSTFSA-N 0.000 description 1
- 229960003646 lysine Drugs 0.000 description 1
- GVALZJMUIHGIMD-UHFFFAOYSA-H magnesium phosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GVALZJMUIHGIMD-UHFFFAOYSA-H 0.000 description 1
- 229960002261 magnesium phosphate Drugs 0.000 description 1
- 229910000157 magnesium phosphate Inorganic materials 0.000 description 1
- 239000004137 magnesium phosphate Substances 0.000 description 1
- 235000010994 magnesium phosphates Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 229960003632 minoxidil Drugs 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002522 swelling effect Effects 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9600018A FR2742987B1 (fr) | 1996-01-03 | 1996-01-03 | Utilisation dans le domaine de la cosmetique et de la pharmacie, notamment de la dermatologie, d'un extrait d'eriobotrya japonica pour stimuler la synthese des glycosaminoglycanes |
| FR9600018 | 1996-01-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL1004939A1 NL1004939A1 (nl) | 1997-07-07 |
| NL1004939C2 true NL1004939C2 (nl) | 1997-07-07 |
Family
ID=9487870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1004939A NL1004939C2 (nl) | 1996-01-03 | 1997-01-06 | Gebruik van een Eriobotrya japonica extract, in het bijzonder in het gebied van de cosmetica, voor het stimuleren van de synthesen van glucosaminoglycanen. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5955083A (de) |
| JP (1) | JPH11501325A (de) |
| AU (1) | AU1181097A (de) |
| BE (1) | BE1010042A3 (de) |
| CH (1) | CH692902A5 (de) |
| DE (1) | DE19780092B3 (de) |
| ES (1) | ES2129014B1 (de) |
| FR (1) | FR2742987B1 (de) |
| GB (1) | GB2314272A (de) |
| IT (1) | IT1290991B1 (de) |
| NL (1) | NL1004939C2 (de) |
| WO (1) | WO1997006659A2 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5874094A (en) * | 1997-08-05 | 1999-02-23 | Costello; Jeremiah | Cream formulation for topical application |
| FR2767057B1 (fr) * | 1997-08-08 | 1999-10-29 | Lvmh Rech | Utilisation du ginsenoside rb1 comme agent destine a stimuler la synthese de l'elastine |
| FR2768927B1 (fr) * | 1997-10-01 | 2000-01-21 | Lvmh Rech | Utilisation de l'acide ellagique, de ses sels, de ses complexes metalliques, de ses derives mono- ou poly-ethers, mono- ou poly-acyles dans le domaine de la cosmetique et de la pharmacie, notamment de la dermatologie |
| PT982990E (pt) * | 1998-02-06 | 2007-01-31 | Ester C Company | Composições líquidas estáveis de ascorbato de cálcio e métodos de preparação e utilização |
| KR100371416B1 (ko) | 1998-03-16 | 2003-02-07 | 더 프록터 앤드 갬블 캄파니 | 피부 외형을 조절하는 조성물 |
| JP3816262B2 (ja) * | 1998-09-30 | 2006-08-30 | 花王株式会社 | セラミド産生促進剤 |
| US6783546B2 (en) | 1999-09-13 | 2004-08-31 | Keraplast Technologies, Ltd. | Implantable prosthetic or tissue expanding device |
| US6371984B1 (en) | 1999-09-13 | 2002-04-16 | Keraplast Technologies, Ltd. | Implantable prosthetic or tissue expanding device |
| PT1220680E (pt) | 1999-09-30 | 2008-06-25 | Factors R & D Technologies Ltd | Suplemento de echinacea e método de fabrico |
| JP3256746B2 (ja) | 2000-03-02 | 2002-02-12 | 高知医科大学長 | 細胞線維化を抑制する組成物及び枇杷核エキスの調製方法 |
| US20020182237A1 (en) * | 2001-03-22 | 2002-12-05 | The Procter & Gamble Company | Skin care compositions containing a sugar amine |
| EP2465491A1 (de) * | 2002-06-25 | 2012-06-20 | Shiseido Company, Ltd. | Anti-Aging-Präparat |
| KR100485326B1 (ko) * | 2002-12-26 | 2005-04-27 | 주식회사 태평양 | 진세노사이드 화합물 k로 이루어진 히알루론산 생성촉진제 |
| JP2005247826A (ja) * | 2004-02-04 | 2005-09-15 | Kose Corp | デコリン産生促進剤及びそれを含有する皮膚外用剤 |
| WO2006109888A1 (ja) * | 2005-04-13 | 2006-10-19 | Shiseido Company, Ltd. | 抗シワ剤 |
| JP2007197371A (ja) * | 2006-01-26 | 2007-08-09 | Yaizu Suisankagaku Industry Co Ltd | 美肌促進剤及び美容健康食品 |
| FR2932086A1 (fr) * | 2008-06-06 | 2009-12-11 | Lvmh Rech | Methode de soin cosmetique anti-age par stimulation de l'expression de la survivine |
| JP2011084539A (ja) * | 2009-10-19 | 2011-04-28 | Meiko Shoji Kk | 化粧料および化粧料シート |
| EP2924432B1 (de) | 2011-05-17 | 2017-07-05 | Chanel Parfums Beauté | Criblage d'activateurs de hs6st2 pour la prévention et/ou l'atténuation du vieillissement de la peau et/ou pour l'hydratation de la peau |
| CN104666145B (zh) * | 2013-11-28 | 2018-09-04 | 上海家化联合股份有限公司 | 一种用于紫外损伤修复和促进能量代谢的中草药及其在化妆品中的应用 |
| EP4110461A4 (de) * | 2020-02-25 | 2024-05-01 | Amplifica, Inc. | Zusammensetzungen und verfahren zur stimulierung des haarwachstums |
| JP7742622B2 (ja) * | 2020-12-09 | 2025-09-22 | 丸善製薬株式会社 | ヒアルロン酸産生促進剤 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2068433A1 (en) * | 1969-11-18 | 1971-08-27 | Garcia Jose | Japanese medlar antihaemorrhoidal extracts |
| JPS53136506A (en) * | 1977-05-02 | 1978-11-29 | Mototaka Ueno | Production of bathing agent being nontoxious to human and animal used in squeezed towell and bath waer to wipe body of0patient * old man and disabled parson |
| JPS6267028A (ja) * | 1985-09-18 | 1987-03-26 | Shiseido Co Ltd | 肌荒れ防止剤 |
| JPS62249907A (ja) * | 1986-04-22 | 1987-10-30 | Eikoudou:Kk | 化粧料 |
| JPH0629167B2 (ja) * | 1986-05-09 | 1994-04-20 | 株式会社資生堂 | 毛髪化粧料 |
| JPS63115807A (ja) * | 1986-11-04 | 1988-05-20 | Eikoudou:Kk | 化粧料 |
| JPH03188008A (ja) * | 1989-12-15 | 1991-08-16 | Shiseido Co Ltd | 化粧料 |
| JP2977672B2 (ja) * | 1992-06-03 | 1999-11-15 | 鐘紡株式会社 | 浴剤組成物 |
| JPH07215838A (ja) * | 1994-02-04 | 1995-08-15 | Shiseido Co Ltd | 皮膚外用剤 |
| JPH0873314A (ja) * | 1994-09-05 | 1996-03-19 | Ichimaru Pharcos Co Ltd | 皮膚外用剤および浴用剤 |
| JP3667376B2 (ja) * | 1995-02-15 | 2005-07-06 | 御木本製薬株式会社 | ヒアルロニターゼ阻害剤 |
-
1996
- 1996-01-03 FR FR9600018A patent/FR2742987B1/fr not_active Expired - Lifetime
-
1997
- 1997-01-02 IT IT97TO000001A patent/IT1290991B1/it active IP Right Grant
- 1997-01-03 DE DE19780092T patent/DE19780092B3/de not_active Expired - Lifetime
- 1997-01-03 AU AU11810/97A patent/AU1181097A/en not_active Abandoned
- 1997-01-03 WO PCT/FR1997/000009 patent/WO1997006659A2/fr not_active Ceased
- 1997-01-03 US US08/894,701 patent/US5955083A/en not_active Expired - Lifetime
- 1997-01-03 BE BE9700001A patent/BE1010042A3/fr not_active IP Right Cessation
- 1997-01-03 GB GB9718684A patent/GB2314272A/en not_active Withdrawn
- 1997-01-03 JP JP9508997A patent/JPH11501325A/ja active Pending
- 1997-01-03 CH CH02066/97A patent/CH692902A5/fr not_active IP Right Cessation
- 1997-01-06 NL NL1004939A patent/NL1004939C2/nl not_active IP Right Cessation
- 1997-09-03 ES ES009750020A patent/ES2129014B1/es not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5955083A (en) | 1999-09-21 |
| DE19780092B3 (de) | 2012-05-24 |
| CH692902A5 (fr) | 2002-12-13 |
| IT1290991B1 (it) | 1998-12-14 |
| FR2742987A1 (fr) | 1997-07-04 |
| GB2314272A (en) | 1997-12-24 |
| JPH11501325A (ja) | 1999-02-02 |
| WO1997006659A2 (fr) | 1997-02-27 |
| NL1004939A1 (nl) | 1997-07-07 |
| FR2742987B1 (fr) | 1998-04-03 |
| DE19780092T1 (de) | 1998-02-26 |
| ES2129014A1 (es) | 1999-05-16 |
| ES2129014B1 (es) | 2000-02-16 |
| BE1010042A3 (fr) | 1997-12-02 |
| GB9718684D0 (en) | 1997-11-05 |
| ITTO970001A1 (it) | 1998-07-02 |
| WO1997006659A3 (fr) | 1997-10-23 |
| AU1181097A (en) | 1997-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL1004939C2 (nl) | Gebruik van een Eriobotrya japonica extract, in het bijzonder in het gebied van de cosmetica, voor het stimuleren van de synthesen van glucosaminoglycanen. | |
| KR102807168B1 (ko) | 피키아 아노말라 추출물 및 치커리 뿌리 추출물을 포함하는 국소용 조성물 | |
| JPH05504757A (ja) | スキンケア製剤 | |
| US11285093B2 (en) | Cosmetic uses of swertiamarin | |
| JP4388289B2 (ja) | 皮膚老化防止・改善剤及び/又は肌荒れ防止・改善剤キット | |
| KR20100135871A (ko) | 섬유모세포의 증식 및/또는 활성을 자극하는 활성 성분 | |
| KR100892888B1 (ko) | 표피세포에 있어서의 라미닌 5 생산능을 증강시킬 수 있는물질 및 이들의 사용 | |
| JP2000191498A (ja) | コラ―ゲン産生促進剤および皮膚外用剤 | |
| JP2020529420A (ja) | ネフェリウム・ラパセウム(Nephelium lappaceum)抽出物の新規な美容的使用 | |
| US6193975B1 (en) | Use of potentilla erecta extract in the cosmetic and pharmaceutical field | |
| FR2735981A1 (fr) | Composition cosmetique ou pharmaceutique contenant un extrait de plante du genre foetidia | |
| JP3172753B2 (ja) | 生体ヒアルロン酸合成促進剤 | |
| JP3449624B2 (ja) | 化粧料および燕窩抽出物の製造方法 | |
| JP2578341B2 (ja) | 皮膚外用剤 | |
| JPWO1999022709A1 (ja) | 化粧料および燕窩抽出物の製造方法 | |
| EP0835121A1 (de) | Kosmetische oder pharmazeutische zusammensetzung, enthaltend einen pflanzenextrakt der gattung filicium, und anwendung dieses extrakts zur stimulation der glycosaminglycan-synthese | |
| JP3432175B2 (ja) | 細胞増殖促進化粧料 | |
| JPS6277308A (ja) | 化粧料 | |
| JP2003342179A (ja) | 老化防止剤 | |
| KR101436819B1 (ko) | 피부 보습, 진정 및 여드름 개선용 화장료 조성물 | |
| JP7289833B2 (ja) | 植物ゾウゲ抽出物(ファイテレファス属種(Phytelephas sp.))の化粧的使用 | |
| EP1009378A1 (de) | Verwendung von extrakten der planze rhoeoo discolor im kosmetikbereich und in der pharmazie, insbesondere in der dermatologie | |
| JP2009234976A (ja) | 細胞賦活剤、及び老化防止用皮膚外用剤 | |
| JP7485336B2 (ja) | MSX-2 mRNA発現促進剤、まつ毛の育毛剤、及びまつ毛の育毛用外用剤組成物 | |
| RU2825635C2 (ru) | Композиции для местного нанесения, содержащие pichia anomala и n-ацетилглюкозамин |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1B | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| AD1A | A request for search or an international type search has been filed | ||
| PD2A | A request for search or an international type search has been filed | ||
| BV | The patent application has lapsed | ||
| VD1 | Lapsed due to non-payment of the annual fee |
Effective date: 20070801 |