NI201900004A - Composición vaginal comprendiendo una combinación de estrógeno y vitamina d. - Google Patents
Composición vaginal comprendiendo una combinación de estrógeno y vitamina d.Info
- Publication number
- NI201900004A NI201900004A NI201900004A NI201900004A NI201900004A NI 201900004 A NI201900004 A NI 201900004A NI 201900004 A NI201900004 A NI 201900004A NI 201900004 A NI201900004 A NI 201900004A NI 201900004 A NI201900004 A NI 201900004A
- Authority
- NI
- Nicaragua
- Prior art keywords
- vitamin
- estrogen
- combination
- composition including
- vaginal composition
- Prior art date
Links
- 229940011871 estrogen Drugs 0.000 title abstract 4
- 239000000262 estrogen Substances 0.000 title abstract 4
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- 229930003316 Vitamin D Natural products 0.000 abstract 4
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 4
- 235000019166 vitamin D Nutrition 0.000 abstract 4
- 239000011710 vitamin D Substances 0.000 abstract 4
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 4
- 229940046008 vitamin d Drugs 0.000 abstract 4
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229930182833 estradiol Natural products 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/065—Diphenyl-substituted acyclic alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Composición vaginal que comprende una combinación de estrógeno y vitamina D o un análogo de vitamina D a una administración de dosificación diaria de (i) estrógeno que varía de 1 µg a 100 µg de estrógeno de equivalente de estradiol y (ii) vitamina D o análogo que varía de 7,5 µg a 100 µg de vitamina D equivalente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16305941.3A EP3272333A1 (en) | 2016-07-22 | 2016-07-22 | Vaginal composition comprising a combination of estrogen and vitamin d |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NI201900004A true NI201900004A (es) | 2019-04-29 |
Family
ID=56561320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NI201900004A NI201900004A (es) | 2016-07-22 | 2019-01-18 | Composición vaginal comprendiendo una combinación de estrógeno y vitamina d. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20190224213A1 (es) |
| EP (2) | EP3272333A1 (es) |
| BR (1) | BR112019001207A2 (es) |
| CL (1) | CL2019000174A1 (es) |
| CO (1) | CO2019000604A2 (es) |
| CR (1) | CR20190026A (es) |
| MX (1) | MX390231B (es) |
| NI (1) | NI201900004A (es) |
| PH (1) | PH12019500137A1 (es) |
| WO (1) | WO2018015503A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| EP3787659A1 (en) * | 2018-05-04 | 2021-03-10 | The Procter & Gamble Company | Compositions and methods for treating vaginal atrophy |
| WO2019213473A1 (en) | 2018-05-04 | 2019-11-07 | The Procter & Gamble Company | Compositions and methods for treating vaginal dryness |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
| EP4066824A1 (en) * | 2021-03-31 | 2022-10-05 | Dompe' Farmaceutici S.P.A. | Combination therapy for covid-19 vaccination |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3062715A (en) | 1953-11-18 | 1962-11-06 | George S Pfaus | Vaginal tablet |
| IE61236B1 (en) | 1986-07-15 | 1994-10-19 | American Home Prod | Combination dosage form for pre-menopausal women |
| GB8723846D0 (en) | 1987-10-10 | 1987-11-11 | Danbiosyst Ltd | Bioadhesive microsphere drug delivery system |
| US5514698A (en) | 1994-03-21 | 1996-05-07 | Ortho Pharmaceutical Corporation | Antifungal vaginal cream composition |
| JP3705620B2 (ja) | 1994-12-28 | 2005-10-12 | 帝国臓器製薬株式会社 | 経粘膜投与用製剤 |
| EP0889724A1 (en) | 1996-02-27 | 1999-01-13 | Rpms Technology Limited | Cox-2 selective inhibitors for managing labour and uterine contractions |
| DE19608423A1 (de) | 1996-03-05 | 1997-09-11 | Merck Patent Gmbh | Implantate mit phasenweiser Arzneistoffabgabe |
| IL123813A0 (en) | 1997-04-11 | 1998-10-30 | Akzo Nobel Nv | Drug delivery system for two or more active substances |
| US6197327B1 (en) | 1997-06-11 | 2001-03-06 | Umd, Inc. | Device and method for treatment of dysmenorrhea |
| US6905701B2 (en) | 1997-06-11 | 2005-06-14 | Umd, Inc. | Formulations for transmucosal vaginal delivery of bisphosphonates |
| US20050276836A1 (en) | 1997-06-11 | 2005-12-15 | Michelle Wilson | Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents |
| US20040043071A1 (en) | 2002-06-21 | 2004-03-04 | Pauletti Giovanni M. | Intravaginal mucosal or transmucosal delivery of antimigraine and antinausea drugs |
| FR2766710B1 (fr) | 1997-08-04 | 1999-10-29 | Inst Pharma De Rech Applic Et | Composition pharmaceutique, comprime forme a partir de celle-ci et son utilisation comme antiseptique vaginal a action prolongee |
| DE19916419B4 (de) | 1999-04-08 | 2005-06-16 | Schering Ag | Kombinationspräparat aus Vitamin-D-Metaboliten oder Vitamin-D-Analoga und einem Östrogenpartialagonisten zur Behandlung von Osteoporose |
| US6855703B1 (en) * | 2000-03-10 | 2005-02-15 | Endeavor Pharmaceuticals | Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds |
| ATE532521T1 (de) * | 2000-12-15 | 2011-11-15 | Novo Nordisk Femcare Ag | Verwendung eines östrogens bei der herstellung einer östrogenhaltigen zusammensetzung zur behandlung von atrophischer vaginitis |
| US7004171B2 (en) | 2002-02-25 | 2006-02-28 | Hi-Gienic Intra Vaginal Technologies Ltd. | System for transvaginal drug delivery |
| WO2004103232A1 (en) | 2003-05-15 | 2004-12-02 | Apothecus Pharmaceutical Corp. | Dissolvable vaginal deodorizing films and methods of vaginal deodorizing utilizing pliable dissolvable film |
| WO2005016321A1 (en) | 2003-08-15 | 2005-02-24 | Qlt Usa, Inc. | Adhesive bioerodible transmucosal drug delivery system |
| US20050070501A1 (en) | 2003-09-29 | 2005-03-31 | New York Blood Center, Inc. | Water dispersible film |
| US20060040904A1 (en) | 2004-08-17 | 2006-02-23 | Ahmed Salah U | Vaginal cream compositions, kits thereof and methods of using thereof |
| ATE540684T1 (de) | 2005-04-27 | 2012-01-15 | Shenzhen Phlora Biotechnology Ltd | Zubereitung und verfahren zur regulierung und aufrechterhaltung der vaginalen bakterienflora und der normalen acidität in der vagina |
| CA2640432A1 (en) | 2006-01-27 | 2007-08-09 | Duramed Pharmaceuticals, Inc. | Regimens for treatment of conditions related to estrogen deficiency |
| CA2687310A1 (en) | 2007-05-24 | 2008-12-04 | New York Blood Center Inc. | Rapidly dispersible vaginal tablet that provides a bioadhesive gel |
| US20080312198A1 (en) | 2007-06-14 | 2008-12-18 | Rodriguez Gustavo C | Pharmaceutical products containing hormones and a 25-hydroxy vitamin d compound |
| DK2456421T3 (en) | 2009-07-21 | 2017-06-06 | The Population Council Inc | VAGINAL RING consisting of multiple layers with gradient |
| CA2808276A1 (en) | 2010-08-20 | 2012-02-23 | Teva Women's Health, Inc. | Intravaginal devices, methods of making, and uses thereof |
| CN102641548B (zh) | 2011-02-18 | 2016-08-03 | 帕洛阿尔托研究中心公司 | 包括化学品渗透增强剂的透粘膜药物输送装置和方法 |
| KR101785414B1 (ko) | 2011-12-29 | 2017-10-16 | 라보라토리오스 안드로마코 에스.에이. | 여성에서 연속 사용 피임제로서 사용될 수 있는, 멜록시캄 및 유효 성분 방출 조절제를 포함하는 질 고리 |
| WO2013098592A1 (es) | 2011-12-29 | 2013-07-04 | Universidad De Chile | Anillo vaginal que comprende dhea o dhea sulfato y opcionalmente un agente modulador de la liberación del principio activo, útil para aumentar la reserva ovárica en mujeres y para aliviar síntomas asociados a la menopausia |
| ITMI20120867A1 (it) | 2012-05-18 | 2013-11-19 | Labomar S R L | Composizione per il trattamento di lesioni. |
| FR3018193B1 (fr) | 2014-03-10 | 2017-09-08 | Probionov | Comprime vaginal muco-adhesif a liberation prolongee |
| CN107073019B (zh) * | 2014-03-13 | 2020-04-17 | 深圳优丽康生物技术有限公司 | 一种阴道用组合物与该组合物的用途 |
| WO2016054002A1 (en) | 2014-09-29 | 2016-04-07 | Yale University | Progesterone impregnated vaginal ring/pessary |
-
2016
- 2016-07-22 EP EP16305941.3A patent/EP3272333A1/en not_active Withdrawn
-
2017
- 2017-07-20 CR CR20190026A patent/CR20190026A/es unknown
- 2017-07-20 MX MX2019000806A patent/MX390231B/es unknown
- 2017-07-20 EP EP17743316.6A patent/EP3487478A1/en active Pending
- 2017-07-20 BR BR112019001207-9A patent/BR112019001207A2/pt not_active Application Discontinuation
- 2017-07-20 US US16/318,510 patent/US20190224213A1/en not_active Abandoned
- 2017-07-20 WO PCT/EP2017/068391 patent/WO2018015503A1/en not_active Ceased
-
2019
- 2019-01-18 PH PH12019500137A patent/PH12019500137A1/en unknown
- 2019-01-18 NI NI201900004A patent/NI201900004A/es unknown
- 2019-01-22 CO CONC2019/0000604A patent/CO2019000604A2/es unknown
- 2019-01-22 CL CL2019000174A patent/CL2019000174A1/es unknown
-
2020
- 2020-11-19 US US16/952,142 patent/US11590145B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CL2019000174A1 (es) | 2019-06-28 |
| EP3487478A1 (en) | 2019-05-29 |
| PH12019500137A1 (en) | 2019-07-29 |
| CO2019000604A2 (es) | 2019-05-21 |
| CR20190026A (es) | 2019-04-09 |
| MX390231B (es) | 2025-03-20 |
| US20210069210A1 (en) | 2021-03-11 |
| MX2019000806A (es) | 2019-06-20 |
| US20190224213A1 (en) | 2019-07-25 |
| BR112019001207A2 (pt) | 2019-04-30 |
| US11590145B2 (en) | 2023-02-28 |
| EP3272333A1 (en) | 2018-01-24 |
| WO2018015503A1 (en) | 2018-01-25 |
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