NI201200112A - Combinacion triple para reduccion de presion intraocular - Google Patents
Combinacion triple para reduccion de presion intraocularInfo
- Publication number
- NI201200112A NI201200112A NI201200112A NI201200112A NI201200112A NI 201200112 A NI201200112 A NI 201200112A NI 201200112 A NI201200112 A NI 201200112A NI 201200112 A NI201200112 A NI 201200112A NI 201200112 A NI201200112 A NI 201200112A
- Authority
- NI
- Nicaragua
- Prior art keywords
- intraocular pressure
- pressure reduction
- triple combination
- iop
- eye
- Prior art date
Links
- 230000004410 intraocular pressure Effects 0.000 title abstract 6
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 abstract 1
- XYLJNLCSTIOKRM-UHFFFAOYSA-N Alphagan Chemical compound C1=CC2=NC=CN=C2C(Br)=C1NC1=NCCN1 XYLJNLCSTIOKRM-UHFFFAOYSA-N 0.000 abstract 1
- AQOKCDNYWBIDND-FTOWTWDKSA-N bimatoprost Chemical compound CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1 AQOKCDNYWBIDND-FTOWTWDKSA-N 0.000 abstract 1
- 229960002470 bimatoprost Drugs 0.000 abstract 1
- 229960003679 brimonidine Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960004605 timolol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
En el presente instrumento se revelan las composiciones para disminuir la presión intraocular (PIO) de un ojo mediante la combinación de agentes que disminuyen la presión intra-ocular (PIO) bimatoprost, brimonidina y timolol. Además se revelan los métodos para reducir la PIO en el ojo de un sujeto.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28893609P | 2009-12-22 | 2009-12-22 | |
| US36174910P | 2010-07-06 | 2010-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NI201200112A true NI201200112A (es) | 2013-04-09 |
Family
ID=43743470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NI201200112A NI201200112A (es) | 2009-12-22 | 2012-06-22 | Combinacion triple para reduccion de presion intraocular |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20130116254A1 (es) |
| CN (1) | CN102695498A (es) |
| AR (1) | AR079696A1 (es) |
| BR (1) | BR112012017319A2 (es) |
| CL (1) | CL2012001736A1 (es) |
| CO (1) | CO6592061A2 (es) |
| CR (1) | CR20120360A (es) |
| EC (1) | ECSP12012033A (es) |
| GT (1) | GT201200213A (es) |
| IN (1) | IN2012DN06416A (es) |
| MX (1) | MX2012007397A (es) |
| NI (1) | NI201200112A (es) |
| PE (2) | PE20121468A1 (es) |
| TW (1) | TW201143773A (es) |
| WO (1) | WO2011087790A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050244458A1 (en) * | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular neuropathies |
| EP3434257A1 (en) | 2010-07-29 | 2019-01-30 | Allergan, Inc. | Preservative free brimonidine and timolol solutions |
| WO2013163219A1 (en) | 2012-04-24 | 2013-10-31 | Allergan, Inc. | Prostaglandin and vasoconstrictor pharmaceutical compositions and methods of use |
| AU2016233125A1 (en) * | 2015-03-19 | 2017-09-14 | Allergan, Inc. | Fixed dose combination of bromonidine and timolol |
| WO2019246130A1 (en) * | 2018-06-19 | 2019-12-26 | Cella Therapeutics, Llc | Sustained-release drug delivery systems comprising an intraocular pressure lowering agent, a cnp compound, an npr-b compound, a tie-2 agonist, or neurotrophic agent for use for treating glaucoma or ocular hypertension |
| US12064440B2 (en) * | 2022-03-21 | 2024-08-20 | Somerset Therapeutics, Llc | Ophthalmic gel compositions of bimatoprost and timolol and associated methods |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994274A (en) | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
| US5028624A (en) | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
| US5034413A (en) | 1989-07-27 | 1991-07-23 | Allergan, Inc. | Intraocular pressure reducing 9,11-diacyl prostaglandins |
| US7030149B2 (en) * | 2002-04-19 | 2006-04-18 | Allergan, Inc. | Combination of brimonidine timolol for topical ophthalmic use |
| US7851504B2 (en) * | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
-
2010
- 2010-12-21 PE PE2012000877A patent/PE20121468A1/es not_active Application Discontinuation
- 2010-12-21 WO PCT/US2010/061563 patent/WO2011087790A1/en not_active Ceased
- 2010-12-21 BR BR112012017319A patent/BR112012017319A2/pt not_active Application Discontinuation
- 2010-12-21 MX MX2012007397A patent/MX2012007397A/es active IP Right Grant
- 2010-12-21 PE PE2016000624A patent/PE20160904A1/es unknown
- 2010-12-21 CN CN2010800609772A patent/CN102695498A/zh active Pending
- 2010-12-21 US US13/698,182 patent/US20130116254A1/en not_active Abandoned
- 2010-12-22 TW TW099145385A patent/TW201143773A/zh unknown
- 2010-12-22 AR ARP100104881A patent/AR079696A1/es not_active Application Discontinuation
-
2012
- 2012-06-22 GT GT201200213A patent/GT201200213A/es unknown
- 2012-06-22 NI NI201200112A patent/NI201200112A/es unknown
- 2012-06-22 CL CL2012001736A patent/CL2012001736A1/es unknown
- 2012-06-29 CR CR20120360A patent/CR20120360A/es unknown
- 2012-07-11 EC ECSP12012033 patent/ECSP12012033A/es unknown
- 2012-07-19 CO CO12122166A patent/CO6592061A2/es not_active Application Discontinuation
- 2012-07-20 IN IN6416DEN2012 patent/IN2012DN06416A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE20121468A1 (es) | 2012-10-28 |
| CN102695498A (zh) | 2012-09-26 |
| US20130116254A1 (en) | 2013-05-09 |
| AR079696A1 (es) | 2012-02-15 |
| WO2011087790A1 (en) | 2011-07-21 |
| TW201143773A (en) | 2011-12-16 |
| CL2012001736A1 (es) | 2012-10-12 |
| BR112012017319A2 (pt) | 2016-04-19 |
| CO6592061A2 (es) | 2013-01-02 |
| GT201200213A (es) | 2014-08-29 |
| MX2012007397A (es) | 2012-08-15 |
| PE20160904A1 (es) | 2016-09-16 |
| CR20120360A (es) | 2012-07-30 |
| IN2012DN06416A (es) | 2015-10-09 |
| ECSP12012033A (es) | 2012-10-30 |
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