|
WO2008010101A2
(en)
|
2006-07-18 |
2008-01-24 |
Sanofi-Aventis |
Antagonist antibody against epha2 for the treatment of cancer
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
PT2019104E
(pt)
*
|
2007-07-19 |
2013-12-03 |
Sanofi Sa |
Agentes citotóxicos compreendendo novos derivados de tomaimicina e sua utilização terapêutica
|
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
AU2010210646B2
(en)
|
2009-02-05 |
2015-10-29 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
|
FR2947269B1
(fr)
|
2009-06-29 |
2013-01-18 |
Sanofi Aventis |
Nouveaux composes anticancereux
|
|
FR2949469A1
(fr)
*
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
TW201116297A
(en)
|
2009-10-02 |
2011-05-16 |
Sanofi Aventis |
Antibodies that specifically bind to the EphA2 receptor
|
|
KR20130009760A
(ko)
|
2010-02-10 |
2013-01-23 |
이뮤노젠 아이엔씨 |
Cd20 항체 및 이의 용도
|
|
NZ602933A
(en)
|
2010-04-15 |
2014-09-26 |
Seattle Genetics Inc |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
|
MA34277B1
(fr)
*
|
2010-04-15 |
2013-06-01 |
Spirogen Developments Sarl |
Pyrrolobenzodiazépines et conjugués de celles-ci
|
|
JP5870400B2
(ja)
*
|
2010-04-15 |
2016-03-01 |
シアトル ジェネティクス,インコーポレーテッド |
標的化ピロロベンゾジアゼピンコンジュゲート
|
|
FR2963007B1
(fr)
|
2010-07-26 |
2013-04-05 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application therapeutique
|
|
MY183977A
(en)
|
2011-02-15 |
2021-03-17 |
Immunogen Inc |
Cytotoxic benzodiazepine derivatives
|
|
WO2012145112A2
(en)
*
|
2011-04-18 |
2012-10-26 |
Immunogen, Inc. |
Novel maytansinoid derivatives with sulfoxide linker
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
WO2013041606A1
(en)
|
2011-09-20 |
2013-03-28 |
Spirogen Sàrl |
Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates
|
|
WO2013053871A1
(en)
|
2011-10-14 |
2013-04-18 |
Spirogen Sàrl |
Pyrrolobenzodiazepines
|
|
AU2012322613B2
(en)
|
2011-10-14 |
2016-04-21 |
Medimmune Limited |
Pyrrolobenzodiazepines and targeted conjugates
|
|
EP2751111B1
(en)
|
2011-10-14 |
2017-04-26 |
MedImmune Limited |
Asymmetrical bis-(5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one) derivatives for the treatment of proliferative or autoimmune diseases
|
|
JP6393617B2
(ja)
|
2011-10-14 |
2018-09-19 |
シアトル ジェネティクス,インコーポレーテッド |
ピロロベンゾジアゼピンおよび標的コンジュゲート
|
|
DK2750713T3
(en)
*
|
2011-10-14 |
2015-12-21 |
Medimmune Ltd |
PYRROLOBENZODIAZEPINS AND CONJUGATES THEREOF
|
|
PH12020500604A1
(en)
|
2012-02-24 |
2023-06-14 |
Abbvie Stemcentrx Llc |
Anti sez6 antibodies and methods of use
|
|
JP6089047B2
(ja)
|
2012-02-24 |
2017-03-01 |
アッヴィ・ステムセントルクス・エル・エル・シー |
Dll3モジュレーター及び使用方法
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
AU2013256596A1
(en)
|
2012-05-01 |
2014-10-09 |
Genentech, Inc. |
Anti-PMEL17 antibodies and immunoconjugates
|
|
HK1207388A1
(en)
|
2012-05-15 |
2016-01-29 |
Seattle Genetics, Inc. |
Self-stabilizing linker conjugates
|
|
WO2013177481A1
(en)
|
2012-05-25 |
2013-11-28 |
Immunogen, Inc. |
Benzodiazepines and conjugates thereof
|
|
KR20150027829A
(ko)
|
2012-07-09 |
2015-03-12 |
제넨테크, 인크. |
항-cd22 항체를 포함하는 면역접합체
|
|
SG11201500093TA
(en)
|
2012-07-09 |
2015-02-27 |
Genentech Inc |
Immunoconjugates comprising anti-cd79b antibodies
|
|
US9464141B2
(en)
|
2012-08-02 |
2016-10-11 |
Genentech, Inc. |
Anti-ETBR antibodies and immunoconjugates
|
|
HK1211208A1
(zh)
|
2012-08-22 |
2016-05-20 |
Immunogen, Inc. |
細胞毒性苯並二氮呯衍生物
|
|
WO2014057114A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
|
EP2906296B1
(en)
|
2012-10-12 |
2018-03-21 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
|
KR101995621B1
(ko)
|
2012-10-12 |
2019-07-03 |
에이디씨 테라퓨틱스 에스에이 |
피롤로벤조디아제핀-항-cd22 항체 컨주게이트
|
|
JP6270859B2
(ja)
|
2012-10-12 |
2018-01-31 |
エイディーシー・セラピューティクス・エス・アー・エール・エルAdc Therapeutics Sarl |
ピロロベンゾジアゼピン−抗体結合体
|
|
EP2906249B1
(en)
|
2012-10-12 |
2018-06-27 |
MedImmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
|
DK2906248T3
(en)
|
2012-10-12 |
2019-03-04 |
Medimmune Ltd |
Pyrrolobenzodiazepines and their conjugates
|
|
US9931414B2
(en)
|
2012-10-12 |
2018-04-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
JP5993093B2
(ja)
|
2012-10-12 |
2016-09-14 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン類およびその複合体
|
|
US10695433B2
(en)
|
2012-10-12 |
2020-06-30 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
JP6133431B2
(ja)
|
2012-11-24 |
2017-05-24 |
ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ.Hangzhou Dac Biotech Co.,Ltd. |
親水性連結体及び薬物分子と細胞結合分子との共役反応における親水性連結体の使用
|
|
HK1216176A1
(zh)
|
2012-12-21 |
2016-10-21 |
Medlmmune Limited |
用於治疗增殖性和自身免疫疾病的非对称吡咯并苯并二氮杂卓二聚物
|
|
EP2745876A1
(en)
|
2012-12-21 |
2014-06-25 |
Prous Institute for Biomedical Research, S.A. |
Hydroxy aliphatic substituted phenyl aminoalkyl ether derivatives
|
|
AU2013366493B2
(en)
|
2012-12-21 |
2017-08-24 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
SMT201900339T1
(it)
|
2013-02-22 |
2019-07-11 |
Medimmune Ltd |
Coniugati anticorpo anti-dll3/pbd e loro usi
|
|
AU2014229529B2
(en)
|
2013-03-13 |
2018-02-15 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2014159981A2
(en)
|
2013-03-13 |
2014-10-02 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
AU2014230735B2
(en)
|
2013-03-13 |
2018-03-15 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3299391B1
(en)
|
2013-03-14 |
2019-12-04 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
US10442836B2
(en)
|
2013-08-12 |
2019-10-15 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1H-benzo[E]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
|
JP2016538318A
(ja)
|
2013-08-28 |
2016-12-08 |
ステムセントリックス, インコーポレイテッド |
新規sez6モジュレーターおよび使用方法
|
|
EP3892294A1
(en)
|
2013-08-28 |
2021-10-13 |
AbbVie Stemcentrx LLC |
Site-specific antibody conjugation methods and compositions
|
|
NZ717003A
(en)
|
2013-09-02 |
2019-05-31 |
Hangzhou Dac Biotech Co Ltd |
Novel cytotoxic agents for conjugation of drugs to cell binding molecule
|
|
JP2016537399A
(ja)
|
2013-09-17 |
2016-12-01 |
ジェネンテック, インコーポレイテッド |
抗lgr5抗体を使用する方法
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
|
MX2021008464A
(es)
|
2013-10-15 |
2023-03-03 |
Seattle Genetics Inc |
Farmaco-enlazadores modificados con polietilenglicol para la farmacocinetica mejorada de conjugados de ligando-farmaco.
|
|
JP6515111B2
(ja)
|
2013-11-06 |
2019-05-22 |
アッヴィ・ステムセントルクス・エル・エル・シー |
新規の抗クローディン抗体および使用方法
|
|
CA2932476A1
(en)
|
2013-12-12 |
2015-06-18 |
Stemcentrx, Inc. |
Novel anti-dpep3 antibodies and methods of use
|
|
SG11201604784XA
(en)
|
2013-12-13 |
2016-07-28 |
Genentech Inc |
Anti-cd33 antibodies and immunoconjugates
|
|
BR112016013258A2
(pt)
|
2013-12-16 |
2018-01-16 |
Genentech Inc |
composto conjugado anticorpo-droga, composição farmacêutica, método para tratar câncer e kit
|
|
CN106456725B9
(zh)
|
2014-02-11 |
2022-08-09 |
西雅图基因公司 |
蛋白质的选择性还原
|
|
BR112016018891A2
(pt)
|
2014-02-21 |
2017-10-10 |
Abbvie Stemcentrx Llc |
anticorpos anti-dll3 e conjugados de fármacos para uso em melanoma
|
|
US10464955B2
(en)
|
2014-02-28 |
2019-11-05 |
Hangzhou Dac Biotech Co., Ltd. |
Charged linkers and their uses for conjugation
|
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
|
GB201407816D0
(en)
|
2014-05-02 |
2014-06-18 |
King S College London |
Pyrrolobenzodiazepine Compounds
|
|
WO2015179658A2
(en)
|
2014-05-22 |
2015-11-26 |
Genentech, Inc. |
Anti-gpc3 antibodies and immunoconjugates
|
|
WO2016008112A1
(en)
|
2014-07-16 |
2016-01-21 |
Medshine Discovery Inc. |
Linkers and application towards adc thereof
|
|
MX2017002605A
(es)
|
2014-08-28 |
2017-05-19 |
Bioatla Llc |
Receptores de antigeno quimerico condicionalmente activos para celulas t modificadas.
|
|
CN109147874A
(zh)
*
|
2014-09-02 |
2019-01-04 |
伊缪诺金公司 |
用于配制抗体药物缀合物组合物的方法
|
|
TW201613930A
(en)
|
2014-09-03 |
2016-04-16 |
Immunogen Inc |
Cytotoxic benzodiazepine derivatives
|
|
SG11201701455SA
(en)
|
2014-09-03 |
2017-03-30 |
Immunogen Inc |
Cytotoxic benzodiazepine derivatives
|
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗mfi2抗體及使用方法
|
|
CN106687141A
(zh)
|
2014-09-10 |
2017-05-17 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其缀合物
|
|
PE20170935A1
(es)
|
2014-09-12 |
2017-07-13 |
Genentech Inc |
Anticuerpos anti-her2 e inmunoconjugados
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
BR112017004802A2
(pt)
|
2014-09-12 |
2017-12-12 |
Genentech Inc |
anticorpos anti-cll-1 e imunoconjugados
|
|
CN113698485A
(zh)
|
2014-09-12 |
2021-11-26 |
基因泰克公司 |
抗-b7-h4抗体及免疫缀合物
|
|
MX2017003123A
(es)
|
2014-09-12 |
2017-05-12 |
Genentech Inc |
Anticuerpos y conjugados modificados geneticamente con cisteina.
|
|
BR112017004953A2
(pt)
*
|
2014-09-17 |
2017-12-05 |
Genentech Inc |
imunoconjugado, formulação farmacêutica, método de tratamento e método de inibição da proliferação de uma célula
|
|
SG11201702079UA
(en)
|
2014-09-17 |
2017-04-27 |
Genentech Inc |
Pyrrolobenzodiazepines and antibody disulfide conjugates thereof
|
|
BR112017011111A2
(pt)
|
2014-11-25 |
2017-12-26 |
Adc Therapeutics Sa |
conjugados de pirrolobenzodiazepina-anticorpo
|
|
CN107428780B
(zh)
|
2015-01-14 |
2020-09-04 |
百时美施贵宝公司 |
苯并二氮杂*二聚体、其缀合物及制备和使用方法
|
|
JP6676058B2
(ja)
|
2015-01-14 |
2020-04-08 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
ヘテロアリーレン架橋したベンゾジアゼピン二量体、そのコンジュゲート、ならびに製造および使用方法
|
|
US9504694B2
(en)
*
|
2015-03-19 |
2016-11-29 |
Cellerant Therapeutics, Inc. |
Isoquinolidinobenzodiazepines
|
|
US10206942B2
(en)
|
2015-04-10 |
2019-02-19 |
Thomas Jefferson University |
Methods and compositions for treating cancers and enhancing therapeutic immunity by selectively reducing immunomodulatory M2 monocytes
|
|
GB201506389D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
CA2989269C
(en)
|
2015-06-15 |
2020-09-22 |
Robert Yongxin Zhao |
Hydrophilic linkers for conjugation of a cytotoxic agent or chromophore molecule to a cell-binding molecule
|
|
CN108391434A
(zh)
|
2015-06-23 |
2018-08-10 |
百时美施贵宝公司 |
大环苯并二氮杂*二聚体、其缀合物、制备和用途
|
|
EP3319936B1
(en)
|
2015-07-12 |
2025-12-17 |
Hangzhou Dac Biotech Co., Ltd. |
Bridge linkers for conjugation of cell-binding molecules
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
IL286788B2
(en)
|
2015-07-21 |
2024-01-01 |
Immunogen Inc |
Methods of preparing cytotoxic benzodiazepine derivatives
|
|
US11078286B2
(en)
|
2015-09-20 |
2021-08-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies specific for fibroblast growth factor receptor 4 (FGFR4) and methods of their use
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
CN109843919A
(zh)
|
2016-03-25 |
2019-06-04 |
西雅图基因公司 |
用于制备聚乙二醇化的药物-接头及其中间体的方法
|
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
|
MX395074B
(es)
|
2016-04-15 |
2025-03-24 |
Bioatla Llc |
Anticuerpos anti-axl, fragmentos de anticuerpos y sus inmunoconjugados y usos de los mismos
|
|
CA3021098A1
(en)
|
2016-04-21 |
2017-10-26 |
Abbvie Stemcentrx Llc |
Novel anti-bmpr1b antibodies and methods of use
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017196847A1
(en)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
|
|
TW201808336A
(zh)
|
2016-05-11 |
2018-03-16 |
賽諾菲公司 |
用抗muc1類美登素免疫綴合物抗體治療腫瘤的治療方案
|
|
PL3455261T3
(pl)
|
2016-05-13 |
2022-12-12 |
Bioatla, Inc. |
Przeciwciała anty-ror2, fragmenty przeciwciał, ich immunokoniugaty oraz ich zastosowania
|
|
JP7022080B2
(ja)
|
2016-05-27 |
2022-02-17 |
ジェネンテック, インコーポレイテッド |
部位特異的抗体-薬物複合体の特徴付けのための生化学分析的方法
|
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
|
EP3494135A1
(en)
|
2016-08-02 |
2019-06-12 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Monoclonal antibodies targeting glypican-2 (gpc2) and use thereof
|
|
TWI851531B
(zh)
|
2016-08-09 |
2024-08-11 |
美商思進公司 |
具有改善之生理化學性質之具自我穩定連接子之藥物結合物
|
|
JP7093767B2
(ja)
|
2016-08-11 |
2022-06-30 |
ジェネンテック, インコーポレイテッド |
ピロロベンゾジアゼピンプロドラッグ及びその抗体コンジュゲート
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
KR20220147721A
(ko)
|
2016-11-14 |
2022-11-03 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
|
JP7313684B2
(ja)
|
2016-11-21 |
2023-07-25 |
キュレアブ ゲーエムベーハー |
抗gp73抗体及びイムノコンジュゲート
|
|
JP7244987B2
(ja)
|
2016-12-14 |
2023-03-23 |
シージェン インコーポレイテッド |
多剤抗体薬物コンジュゲート
|
|
AU2017382883B2
(en)
|
2016-12-21 |
2024-07-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies specific for FLT3 and uses thereof
|
|
UA123889C2
(uk)
|
2017-02-08 |
2021-06-16 |
Ейдісі Терапьютікс Са |
Кон'югати піролобензодіазепін-антитіло
|
|
HUE054689T2
(hu)
|
2017-02-08 |
2021-09-28 |
Adc Therapeutics Sa |
Pirrolobenzodiazepin-antitest konjugátumok
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
CN110430901B
(zh)
|
2017-03-24 |
2024-08-16 |
西雅图基因公司 |
制备葡糖苷酸药物-接头及其中间体的方法
|
|
SI3612537T1
(sl)
|
2017-04-18 |
2022-10-28 |
Medimmune Limited |
Konjugati pirolobenzodiazepina
|
|
EP3612234B1
(en)
|
2017-04-20 |
2024-03-13 |
ADC Therapeutics SA |
Combination therapy with an anti-axl antibody-drug conjugate
|
|
TW201839001A
(zh)
|
2017-04-20 |
2018-11-01 |
美商伊繆諾金公司 |
細胞毒性苯并二氮平衍生物及其綴合物
|
|
EP3625256A1
(en)
|
2017-05-19 |
2020-03-25 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Human monoclonal antibody targeting tnfr2 for cancer immunotherapy
|
|
CA3064804A1
(en)
|
2017-06-14 |
2018-12-20 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-cd19 adc
|
|
CA3066953A1
(en)
|
2017-06-30 |
2019-01-03 |
Lentigen Technology, Inc. |
Human monoclonal antibodies specific for cd33 and methods of their use
|
|
WO2019005208A1
(en)
|
2017-06-30 |
2019-01-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
ANTIBODIES TO HUMAN MESOTHELIN AND USES IN ANTICANCER THERAPY
|
|
EP3658172A4
(en)
|
2017-07-25 |
2021-05-05 |
TrueBinding, Inc. |
TREATING CANCER BY BLOCKING THE INTERACTION OF TIM-3 AND HIS LIGAND
|
|
SG11202000358YA
(en)
|
2017-08-18 |
2020-02-27 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
IL273387B2
(en)
|
2017-09-20 |
2023-10-01 |
Ph Pharma Co Ltd |
Thylanstatin analogs
|
|
TWI885539B
(zh)
|
2017-09-29 |
2025-06-01 |
日商第一三共股份有限公司 |
抗體-吡咯并苯二氮呯衍生物複合體
|
|
EP3705471A4
(en)
*
|
2017-11-02 |
2021-08-11 |
UBE Industries, Ltd. |
TWO-HEAD PROTEASE INHIBITOR
|
|
JP2021502969A
(ja)
|
2017-11-14 |
2021-02-04 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン複合体
|
|
TWI827575B
(zh)
|
2017-12-28 |
2024-01-01 |
美商伊繆諾金公司 |
苯二氮平衍生物
|
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
*
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3801630A1
(en)
|
2018-05-25 |
2021-04-14 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
WO2020014482A1
(en)
|
2018-07-12 |
2020-01-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Affinity matured cd22-specific monoclonal antibody and uses thereof
|
|
US12377164B2
(en)
|
2018-07-31 |
2025-08-05 |
Astrazeneca Ab |
Linkers and conjugates
|
|
CA3106544A1
(en)
|
2018-08-08 |
2020-02-13 |
Mitchell Ho |
High affinity monoclonal antibodies targeting glypican-2 and uses thereof
|
|
KR20210081350A
(ko)
|
2018-10-19 |
2021-07-01 |
메드임뮨 리미티드 |
피롤로벤조디아제핀 컨쥬게이트
|
|
EP3866857A1
(en)
|
2018-10-19 |
2021-08-25 |
MedImmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
GB201820725D0
(en)
|
2018-12-19 |
2019-01-30 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine resistance
|
|
US20220347309A1
(en)
|
2018-12-19 |
2022-11-03 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine resistance
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
WO2020141923A2
(ko)
*
|
2019-01-03 |
2020-07-09 |
주식회사 레고켐 바이오사이언스 |
안전성이 향상된 피롤로벤조디아제핀 이량체 화합물 및 이의 용도
|
|
CA3125484A1
(en)
|
2019-01-08 |
2020-07-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Cross-species single domain antibodies targeting mesothelin for treating solid tumors
|
|
EP3883971A1
(en)
|
2019-01-22 |
2021-09-29 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
High affinity monoclonal antibodies targeting glypican-1 and methods of use
|
|
CN120058944A
(zh)
|
2019-01-30 |
2025-05-30 |
真和制药有限公司 |
抗gal3抗体及其用途
|
|
MX2021010477A
(es)
|
2019-03-15 |
2021-10-01 |
Medimmune Ltd |
Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer.
|
|
KR102679892B1
(ko)
|
2019-03-29 |
2024-07-02 |
메디뮨 리미티드 |
화합물 및 이의 접합체
|
|
TW202102506A
(zh)
|
2019-03-29 |
2021-01-16 |
美商伊繆諾金公司 |
苯二氮平衍生物
|
|
GB201908128D0
(en)
|
2019-06-07 |
2019-07-24 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
CN110483504B
(zh)
*
|
2019-08-02 |
2022-04-26 |
桂林理工大学 |
以DMF为甲酰化试剂构建2-(2-萘基)咪唑[1,2-a]吡啶-3-醛的新方法
|
|
WO2021074392A1
(en)
*
|
2019-10-16 |
2021-04-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Visual detection of pbd induced dna crosslinks
|
|
CN119899265A
(zh)
|
2019-10-22 |
2025-04-29 |
美国政府(由卫生和人类服务部的部长所代表) |
用于治疗多种实体瘤的靶向b7h3(cd276)的高亲和力纳米抗体
|
|
WO2021080608A1
(en)
|
2019-10-25 |
2021-04-29 |
Medimmune, Llc |
Branched moiety for use in conjugates
|
|
AU2020402752A1
(en)
|
2019-12-12 |
2022-06-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody-drug conjugates specific for CD276 and uses thereof
|
|
WO2021148500A1
(en)
|
2020-01-22 |
2021-07-29 |
Medimmune Limited |
Compounds and conjugates thereof
|
|
TW202140076A
(zh)
|
2020-01-22 |
2021-11-01 |
英商梅迪繆思有限公司 |
化合物及其軛合物
|
|
TW202144572A
(zh)
|
2020-03-19 |
2021-12-01 |
美商亞維代堤生物科學公司 |
治療臉肩胛肱骨肌肉失養症之組合物及方法
|
|
BR112022019137A2
(pt)
|
2020-03-27 |
2023-01-31 |
Avidity Biosciences Inc |
Composições e métodos de tratamento de distrofia muscular
|
|
BR112022020332A2
(pt)
|
2020-04-10 |
2022-12-13 |
Seagen Inc |
Composto conjugado anticorpo-droga, composição, método de tratamento de câncer e de um distúrbio autoimune
|
|
MX2022014786A
(es)
|
2020-05-26 |
2023-01-16 |
Truebinding Inc |
Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3.
|
|
WO2022093745A1
(en)
|
2020-10-26 |
2022-05-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies targeting sars coronavirus spike protein and uses thereof
|
|
JP2024511360A
(ja)
|
2021-03-18 |
2024-03-13 |
シージェン インコーポレイテッド |
生体活性化合物の内部移行複合体からの選択的薬物放出
|
|
AU2022238571A1
(en)
|
2021-03-18 |
2023-09-14 |
Seagen Inc. |
Selective drug release from internalized conjugates of biologically active compounds
|
|
GB202105187D0
(en)
|
2021-04-12 |
2021-05-26 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
GB202105186D0
(en)
|
2021-04-12 |
2021-05-26 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
WO2022232612A1
(en)
|
2021-04-29 |
2022-11-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Lassa virus-specific nanobodies and methods of their use
|
|
US20240270851A1
(en)
|
2021-06-09 |
2024-08-15 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Cross species single domain antibodies targeting pd-l1 for treating solid tumors
|
|
WO2023288252A1
(en)
|
2021-07-13 |
2023-01-19 |
Truebinding, Inc. |
Methods of preventing protein aggregation
|
|
GB202110726D0
(en)
|
2021-07-26 |
2021-09-08 |
Cambridge Entpr Ltd |
Conjugating reagents and conjugates thereof
|
|
CA3231330A1
(en)
|
2021-09-16 |
2023-03-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
|
AU2021362997A1
(en)
|
2021-11-03 |
2024-05-16 |
Hangzhou Dac Biotech Co., Ltd. |
Specific conjugation of an antibody
|
|
AU2022388722A1
(en)
|
2021-11-09 |
2024-05-23 |
Truebinding, Inc. |
Methods of treating or inhibiting cardiovascular diseases
|
|
CN119137157A
(zh)
|
2022-05-03 |
2024-12-13 |
基因泰克公司 |
抗Ly6E抗体、免疫缀合物及其用途
|
|
GB202207691D0
(en)
|
2022-05-25 |
2022-07-06 |
Cambridge Entpr Ltd |
Quinone protected forms and conjugates
|
|
WO2024129756A1
(en)
|
2022-12-13 |
2024-06-20 |
Seagen Inc. |
Site-specific engineered cysteine antibody drug conjugates
|
|
WO2025019228A1
(en)
|
2023-07-20 |
2025-01-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Fully human monoclonal antibodies and chimeric antigen receptors against cd276 for the treatment of solid tumors
|
|
EP4509142A1
(en)
|
2023-08-16 |
2025-02-19 |
Ona Therapeutics S.L. |
Fgfr4 as target in cancer treatment
|
|
WO2025149947A1
(en)
|
2024-01-12 |
2025-07-17 |
Seagen Inc. |
Antibody-drug conjugates
|
|
WO2025171238A1
(en)
|
2024-02-07 |
2025-08-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind the juxta-membrane region of mesothelin and uses thereof
|