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MXPA05010783A - Derivados antimicrobianos de [3.1.0] biciclohexilfenil-oxazolidinona y analogos. - Google Patents

Derivados antimicrobianos de [3.1.0] biciclohexilfenil-oxazolidinona y analogos.

Info

Publication number
MXPA05010783A
MXPA05010783A MXPA05010783A MXPA05010783A MXPA05010783A MX PA05010783 A MXPA05010783 A MX PA05010783A MX PA05010783 A MXPA05010783 A MX PA05010783A MX PA05010783 A MXPA05010783 A MX PA05010783A MX PA05010783 A MXPA05010783 A MX PA05010783A
Authority
MX
Mexico
Prior art keywords
bicyclohexylphenyl
analogues
antimicrobial
oxazolidinone derivatives
methods
Prior art date
Application number
MXPA05010783A
Other languages
English (en)
Inventor
Prasad Venkata Nagendra J Vara
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of MXPA05010783A publication Critical patent/MXPA05010783A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencion provee ciertos derivados biciclicos de [3.1.0] oxazolidinona de Formula I (ver Formula I) o sus sales o profarmacos farmaceuticamente aceptables que son agentes antibacterianos, composiciones farmaceuticas que los contienen, metodos para su uso y metodos para preparar estos compuestos.
MXPA05010783A 2003-04-09 2004-03-30 Derivados antimicrobianos de [3.1.0] biciclohexilfenil-oxazolidinona y analogos. MXPA05010783A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46113403P 2003-04-09 2003-04-09
PCT/IB2004/001135 WO2004089943A1 (en) 2003-04-09 2004-03-30 Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues

Publications (1)

Publication Number Publication Date
MXPA05010783A true MXPA05010783A (es) 2005-12-12

Family

ID=33159819

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05010783A MXPA05010783A (es) 2003-04-09 2004-03-30 Derivados antimicrobianos de [3.1.0] biciclohexilfenil-oxazolidinona y analogos.

Country Status (7)

Country Link
US (2) US7279494B2 (es)
EP (1) EP1615916A1 (es)
JP (1) JP2006522791A (es)
BR (1) BRPI0409217A (es)
CA (1) CA2521685A1 (es)
MX (1) MXPA05010783A (es)
WO (1) WO2004089943A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
MXPA05013132A (es) 2003-06-03 2006-05-25 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo y metodos de produccion y su uso.
ATE471937T1 (de) 2003-07-02 2010-07-15 Merck Sharp & Dohme Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon
WO2005005399A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
JP2007514782A (ja) 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
US8399660B2 (en) 2005-06-08 2013-03-19 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
AU2009318783A1 (en) 2008-11-20 2011-06-23 Panacea Biotec Ltd. Novel antimicrobials
CN102803224A (zh) 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物
JP2013542929A (ja) 2010-09-28 2013-11-28 パナセア バイオテック リミテッド 新規ビシクロ環化合物
KR20130102614A (ko) * 2010-11-03 2013-09-17 욱크하르트 리미티드 인산 모노-(1-[4-[(s)-5-(아세틸아미노메틸)-2-옥소-옥사졸리딘-3-일]-2,6-디플루오로페닐]-4-메톡시메틸피페리딘-4-일) 에스테르의 제조 방법
JP7743829B2 (ja) * 2021-11-05 2025-09-25 小野薬品工業株式会社 Ｋｄｍ５阻害作用を有する化合物を含有する医薬組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
PL337329A1 (en) 1997-05-30 2000-08-14 Upjohn Co Oxazolydinone based antibacterial agents comprising a thiocarbonyl functional group
JP2002501059A (ja) 1998-01-23 2002-01-15 ファルマシア・アンド・アップジョン・カンパニー オキサゾリジノンの組合せライブラリー、組成物および調製方法
NZ508174A (en) 1998-06-05 2003-10-31 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
JP2003518117A (ja) * 1999-12-21 2003-06-03 ファルマシア・アンド・アップジョン・カンパニー スルホキシミン官能基を有するオキサゾリジノンおよび抗微生物剤としてのその使用
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
SK1402003A3 (en) 2000-07-17 2003-08-05 Ranbaxy Lab Ltd Oxazolidinone derivatives as antimicrobials
JP4170753B2 (ja) 2000-10-17 2008-10-22 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー オキサゾリジノン化合物の製造方法
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados

Also Published As

Publication number Publication date
US20050192325A1 (en) 2005-09-01
US7279494B2 (en) 2007-10-09
EP1615916A1 (en) 2006-01-18
WO2004089943A8 (en) 2005-09-29
BRPI0409217A (pt) 2006-03-28
CA2521685A1 (en) 2004-10-21
WO2004089943A1 (en) 2004-10-21
US20080090884A1 (en) 2008-04-17
JP2006522791A (ja) 2006-10-05

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