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MXPA05008619A - Derivados novedosos de 2-piridincarboxamida. - Google Patents

Derivados novedosos de 2-piridincarboxamida.

Info

Publication number
MXPA05008619A
MXPA05008619A MXPA05008619A MXPA05008619A MXPA05008619A MX PA05008619 A MXPA05008619 A MX PA05008619A MX PA05008619 A MXPA05008619 A MX PA05008619A MX PA05008619 A MXPA05008619 A MX PA05008619A MX PA05008619 A MXPA05008619 A MX PA05008619A
Authority
MX
Mexico
Prior art keywords
general formula
novel
sulfur
oxygen
iii
Prior art date
Application number
MXPA05008619A
Other languages
English (en)
Inventor
Jun-Ichi Eiki
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of MXPA05008619A publication Critical patent/MXPA05008619A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Los compuestos representados por la formula general (I) o sales farmaceuticamente aceptables de los mismos, que tienen un efecto activante de la glucocinasa y que son utiles como remedios para la diabetes: (I) en donde X1 es nitrogeno, azufre, oxigeno o lo similar ; R1 es un arilo de 6 a 10 miembros, heteroarilo de 5 a 7 miembros o lo similar; D es oxigeno o azufre; R2 y R3 son cada uno, de manera independiente, hidrogeno, alquilo inferior o lo similar; el anillo A de la formula general (II): (II) es un heteroarilo de 5 a 7 miembros sustituido opcionalmente o lo similar y el anillo B de la formula general (III): (III) es un grupo heteroarilo mono o biciclico.
MXPA05008619A 2003-02-13 2004-02-13 Derivados novedosos de 2-piridincarboxamida. MXPA05008619A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2003034987 2003-02-13
JP2003342860 2003-10-01
JP2004014799 2004-01-22
PCT/JP2004/001568 WO2004081001A1 (ja) 2003-02-13 2004-02-13 新規２－ピリジンカルボキサミド誘導体

Publications (1)

Publication Number Publication Date
MXPA05008619A true MXPA05008619A (es) 2005-11-04

Family

ID=32995582

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05008619A MXPA05008619A (es) 2003-02-13 2004-02-13 Derivados novedosos de 2-piridincarboxamida.

Country Status (20)

Country Link
US (3) US7629362B2 (es)
EP (1) EP1598349B1 (es)
JP (1) JP4400563B2 (es)
KR (1) KR20050101208A (es)
AR (1) AR045414A1 (es)
AT (1) ATE517887T1 (es)
AU (2) AU2004220234C1 (es)
BR (1) BRPI0407283A (es)
CA (1) CA2515841C (es)
EC (1) ECSP056016A (es)
IL (1) IL169905A0 (es)
MA (1) MA27626A1 (es)
MX (1) MXPA05008619A (es)
NO (1) NO20054224L (es)
NZ (1) NZ540791A (es)
PE (1) PE20050194A1 (es)
TW (1) TWI336329B (es)
UA (1) UA82867C2 (es)
WO (1) WO2004081001A1 (es)
ZA (1) ZA200504852B (es)

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AU2004220234C1 (en) 2013-01-17
ECSP056016A (es) 2006-01-27
AU2010200004B2 (en) 2012-07-19
IL169905A0 (en) 2007-07-04
US7629362B2 (en) 2009-12-08
HK1088602A1 (zh) 2006-11-10
WO2004081001A1 (ja) 2004-09-23
ATE517887T1 (de) 2011-08-15
CA2515841A1 (en) 2004-09-23
US20060258701A1 (en) 2006-11-16
NZ540791A (en) 2009-09-25
AU2004220234B2 (en) 2009-11-26
TWI336329B (en) 2011-01-21
BRPI0407283A (pt) 2006-01-31
MA27626A1 (fr) 2005-11-01
AU2004220234A1 (en) 2004-09-23
US8344003B2 (en) 2013-01-01
US8765789B2 (en) 2014-07-01
TW200510381A (en) 2005-03-16
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KR20050101208A (ko) 2005-10-20
NO20054224D0 (no) 2005-09-12
UA82867C2 (en) 2008-05-26
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AU2010200004A1 (en) 2010-01-28
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