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MXPA03005372A - Androgenos 14 (15) -insaturados, 15- y/o 16-sustituidos, con perfil de actividad mixto androgenico-progestacional. - Google Patents

Androgenos 14 (15) -insaturados, 15- y/o 16-sustituidos, con perfil de actividad mixto androgenico-progestacional.

Info

Publication number
MXPA03005372A
MXPA03005372A MXPA03005372A MXPA03005372A MXPA03005372A MX PA03005372 A MXPA03005372 A MX PA03005372A MX PA03005372 A MXPA03005372 A MX PA03005372A MX PA03005372 A MXPA03005372 A MX PA03005372A MX PA03005372 A MXPA03005372 A MX PA03005372A
Authority
MX
Mexico
Prior art keywords
profile
progestational
unsaturated
androgen
mixed
Prior art date
Application number
MXPA03005372A
Other languages
English (en)
Inventor
Leysen Dirk
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of MXPA03005372A publication Critical patent/MXPA03005372A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describen esteroides relacionados con androgeno, que tienen una doble ligadura ?14 y que llevan un sustituyente en cualquiera de los atomos de carbono numeros 15 y 16, o en ambos. Los esteroides de la presente estan caracterizados porque poseen un perfil mixto de actividades androgenicas y progestagenicas. Esto hace que estos compuestos sean adecuados para terapia de reemplazo hormonal masculino o femenino, asi como para anticoncepcion masculina.
MXPA03005372A 2000-12-15 2001-12-10 Androgenos 14 (15) -insaturados, 15- y/o 16-sustituidos, con perfil de actividad mixto androgenico-progestacional. MXPA03005372A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00204543 2000-12-15
PCT/EP2001/014776 WO2002048169A1 (en) 2000-12-15 2001-12-10 14(15)-unsaturated 15- and/or 16- substituted androgens with mixed androgen-progestational profile

Publications (1)

Publication Number Publication Date
MXPA03005372A true MXPA03005372A (es) 2004-04-20

Family

ID=8172438

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03005372A MXPA03005372A (es) 2000-12-15 2001-12-10 Androgenos 14 (15) -insaturados, 15- y/o 16-sustituidos, con perfil de actividad mixto androgenico-progestacional.

Country Status (12)

Country Link
US (1) US20040059140A1 (es)
EP (1) EP1343804A1 (es)
JP (1) JP2004520300A (es)
CN (1) CN1481388A (es)
AR (1) AR034194A1 (es)
AU (1) AU2002229663A1 (es)
BR (1) BR0116127A (es)
CA (1) CA2431328A1 (es)
IL (1) IL156208A0 (es)
MX (1) MXPA03005372A (es)
PE (1) PE20020752A1 (es)
WO (1) WO2002048169A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2492B1 (en) 2003-04-28 2009-10-05 شيرينج ايه جي A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
TW200745156A (en) * 2005-06-17 2007-12-16 Organon Nv Steroids having a mixed androgenic and progestagenic profile
CN110294782B (zh) * 2018-03-22 2023-06-23 天津药业研究院股份有限公司 一种11烯甾体化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042689A (en) * 1960-11-21 1962-07-03 Searle & Co 16-hydrocarbon substituted 16,17-dihydroxyestren-3-ones, their esters and ethers, and intermediates for their production
US3577410A (en) * 1968-07-30 1971-05-04 American Home Prod 13beta-alkyl-17-hydroxygona-4,14-dien-3-ones
ZA712312B (en) * 1970-04-28 1972-01-26 Ochsner Med Found Alton 4,14-estradiene compounds
US3766224A (en) * 1971-06-03 1973-10-16 Sandoz Ag 15-methyl-substituted steroids
DE2920184A1 (de) * 1979-05-17 1980-11-27 Schering Ag 16 alpha -alkylsteroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US5952319A (en) * 1997-11-26 1999-09-14 Research Triangle Institute Androgenic steroid compounds and a method of making and using the same
DE19827522A1 (de) * 1998-06-22 1999-12-23 Jenapharm Gmbh 14,15-Cyclopropanosteroide der 19-Nor-Androstanreihe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
EP1343804A1 (en) 2003-09-17
CA2431328A1 (en) 2002-06-20
PE20020752A1 (es) 2002-08-22
IL156208A0 (en) 2003-12-23
WO2002048169A1 (en) 2002-06-20
AR034194A1 (es) 2004-02-04
BR0116127A (pt) 2003-11-04
CN1481388A (zh) 2004-03-10
JP2004520300A (ja) 2004-07-08
US20040059140A1 (en) 2004-03-25
AU2002229663A1 (en) 2002-06-24

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