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MXPA02012732A - Soluciones de meloxicam estables muy concentradas. - Google Patents

Soluciones de meloxicam estables muy concentradas.

Info

Publication number
MXPA02012732A
MXPA02012732A MXPA02012732A MXPA02012732A MXPA02012732A MX PA02012732 A MXPA02012732 A MX PA02012732A MX PA02012732 A MXPA02012732 A MX PA02012732A MX PA02012732 A MXPA02012732 A MX PA02012732A MX PA02012732 A MXPA02012732 A MX PA02012732A
Authority
MX
Mexico
Prior art keywords
highly concentrated
concentrated stable
meloxicam
meloxicam solutions
stable meloxicam
Prior art date
Application number
MXPA02012732A
Other languages
English (en)
Inventor
Axel Prox
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7646375&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA02012732(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Publication of MXPA02012732A publication Critical patent/MXPA02012732A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Solucion acuosa de meloxicam, administrable por via oral o parenteral y exenta de ciclodextrina, que contiene una sal de meloxicam farmacologicamente compatible de una base organica o inorganica y uno o mas coadyuvantes adecuados, encontrandose el contenido en sal de meloxicam disuelta por encima de 10 mg/ml. La formulacion de acuerdo con la invencion presenta una estabilidad al almacenamiento de hasta 24 meses mayor.
MXPA02012732A 2000-06-20 2001-06-19 Soluciones de meloxicam estables muy concentradas. MXPA02012732A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10030345A DE10030345A1 (de) 2000-06-20 2000-06-20 Hochkonzentrierte stabile Meloxicamlösungen
PCT/EP2001/006904 WO2001097813A2 (en) 2000-06-20 2001-06-19 Highly concentrated stable meloxicam solutions

Publications (1)

Publication Number Publication Date
MXPA02012732A true MXPA02012732A (es) 2004-09-10

Family

ID=7646375

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012732A MXPA02012732A (es) 2000-06-20 2001-06-19 Soluciones de meloxicam estables muy concentradas.

Country Status (31)

Country Link
EP (1) EP1299107B1 (es)
JP (2) JP2003535902A (es)
KR (1) KR100805651B1 (es)
CN (1) CN1236774C (es)
AR (2) AR028967A1 (es)
AT (1) ATE297736T1 (es)
AU (2) AU2001281852B2 (es)
BG (1) BG65798B1 (es)
CA (1) CA2414063C (es)
CZ (1) CZ302717B6 (es)
DE (2) DE10030345A1 (es)
EA (1) EA005765B1 (es)
EC (1) ECSP024371A (es)
EE (1) EE04930B1 (es)
ES (1) ES2244643T3 (es)
HR (1) HRP20021011B1 (es)
HU (1) HU229184B1 (es)
IL (2) IL153114A0 (es)
ME (1) ME00253B (es)
MX (1) MXPA02012732A (es)
MY (1) MY137729A (es)
NO (1) NO330199B1 (es)
NZ (1) NZ523583A (es)
PT (1) PT1299107E (es)
RS (1) RS50142B (es)
SK (1) SK286938B6 (es)
TW (1) TWI250018B (es)
UA (1) UA73584C2 (es)
UY (1) UY26781A1 (es)
WO (1) WO2001097813A2 (es)
ZA (1) ZA200209989B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
EP1348436A1 (en) * 2002-03-30 2003-10-01 Boehringer Ingelheim International GmbH Meloxicam suppositories
JP4707316B2 (ja) * 2002-10-11 2011-06-22 ロート製薬株式会社 水性液状組成物
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
DE10250081A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Vetmedica Gmbh Wasserlösliche Meloxicam Granulate
EP1568369A1 (en) * 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004025324A1 (de) * 2004-05-19 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Flüssige Zubereitung für die Veterinärmedizin, Verfahren zu deren Herstellung und deren Verwendung
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
PL1824493T3 (pl) * 2004-12-06 2009-01-30 Janssen Pharmaceutica Nv Zawiesina zawierająca meloksykam do podawania doustnego
US8097614B2 (en) * 2005-02-17 2012-01-17 Velcera Pharmaceuticals, Inc. Transmucosal administration of meloxicam compositions for treating and preventing disorders in non-human domesticated animals
RU2383344C2 (ru) * 2008-01-22 2010-03-10 Закрытое Акционерное Общество "Канонфарма Продакшн" Фармацевтический раствор мелоксикама и глицина, способ его получения и способ лечения
CN101584696A (zh) * 2008-05-21 2009-11-25 上海艾力斯医药科技有限公司 包含喹唑啉衍生物的组合物及制备方法、用途
TR200809200A1 (tr) 2008-12-01 2009-12-21 Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� Meloksikam içeren farmasötik formülasyonlar
DK4378443T3 (da) 2009-10-12 2025-08-18 Boehringer Ingelheim Vetmedica Gmbh Beholdere til sammensætninger, der omfatter meloxicam
SG183846A1 (en) 2010-03-03 2012-10-30 Boehringer Ingelheim Vetmed Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
KR101045052B1 (ko) * 2011-01-18 2011-06-28 지수광 자세교정용 발받침대
CN102908310A (zh) * 2012-11-02 2013-02-06 青岛康地恩药业股份有限公司 一种犬、猫用治疗类风湿性关节炎的美洛昔康注射液
CN104983686A (zh) * 2015-07-13 2015-10-21 胡涵 畜禽用美洛昔康可溶性粉剂及其制备方法
CN105213402B (zh) * 2015-09-30 2018-12-18 洛阳市兽药厂 一种畜禽复方恩诺沙星美洛昔康可溶性粉
CN116999563A (zh) * 2017-05-10 2023-11-07 艾克萨姆治疗公司 包含美洛昔康的药物组合物
WO2019037757A1 (zh) * 2017-08-24 2019-02-28 江苏恒瑞医药股份有限公司 一种包含美洛昔康的可注射的药物组合物及其制备方法
KR20190107481A (ko) * 2018-03-12 2019-09-20 충북대학교 산학협력단 멜록시캄을 포함하는 구강붕해필름 제조방법 및 이에 의해 제조된 멜록시캄을 포함하는 구강붕해필름
US12059423B2 (en) 2018-05-11 2024-08-13 Nanjing Delova Biotech Co., Ltd. Meloxicam composition, pharmaceutical preparation and preparation method and use thereof
CN112823786A (zh) * 2019-11-21 2021-05-21 北京泰德制药股份有限公司 一种含有美洛昔康的药物组合物及应用
WO2021224815A1 (en) * 2020-05-06 2021-11-11 Cadila Healthcare Limited Stable aqueous parenteral solutions of nonsteroidal anti-inflammatory drug (nsaid)
CN115068419A (zh) * 2022-07-22 2022-09-20 潍坊恒邦兽药有限公司 兽用高浓度美洛昔康注射剂及其加工设备

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DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen

Also Published As

Publication number Publication date
EP1299107B1 (en) 2005-06-15
EE200200701A (et) 2004-08-16
JP5330347B2 (ja) 2013-10-30
CA2414063C (en) 2008-06-17
MEP39808A (en) 2011-02-10
CN1236774C (zh) 2006-01-18
UY26781A1 (es) 2002-01-31
ECSP024371A (es) 2003-02-06
NO330199B1 (no) 2011-03-07
CZ302717B6 (cs) 2011-09-21
AU8185201A (en) 2002-01-02
YU96402A (sh) 2006-01-16
EP1299107A2 (en) 2003-04-09
HK1057859A1 (en) 2004-04-23
DE10030345A1 (de) 2002-01-10
JP2010280726A (ja) 2010-12-16
AU2001281852B2 (en) 2006-04-13
WO2001097813A2 (en) 2001-12-27
JP2003535902A (ja) 2003-12-02
IL153114A (en) 2011-07-31
AR028967A1 (es) 2003-05-28
NZ523583A (en) 2004-09-24
EA005765B1 (ru) 2005-06-30
ES2244643T3 (es) 2005-12-16
DE60111529D1 (de) 2005-07-21
ME00253B (me) 2011-05-10
CZ20024191A3 (cs) 2003-04-16
CN1437472A (zh) 2003-08-20
HUP0300854A2 (hu) 2003-08-28
HRP20021011A2 (en) 2005-02-28
TWI250018B (en) 2006-03-01
ZA200209989B (en) 2003-10-08
DE60111529T2 (de) 2005-12-15
WO2001097813A3 (en) 2002-05-10
SK286938B6 (sk) 2009-07-06
SK17992002A3 (sk) 2003-04-01
RS50142B (sr) 2009-03-25
PL359553A1 (en) 2004-08-23
NO20026132L (no) 2003-02-11
AR100293A2 (es) 2016-09-28
CA2414063A1 (en) 2001-12-27
BG107347A (bg) 2003-09-30
PT1299107E (pt) 2005-08-31
MY137729A (en) 2009-03-31
ATE297736T1 (de) 2005-07-15
HRP20021011B1 (en) 2006-02-28
HU229184B1 (en) 2013-09-30
KR100805651B1 (ko) 2008-02-26
EE04930B1 (et) 2007-12-17
UA73584C2 (en) 2005-08-15
BG65798B1 (bg) 2009-12-31
IL153114A0 (en) 2003-06-24
NO20026132D0 (no) 2002-12-19
EA200201254A1 (ru) 2003-06-26
KR20030013447A (ko) 2003-02-14

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