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MXPA02012682A - Metodo para administrar bisfosfonatos. - Google Patents

Metodo para administrar bisfosfonatos.

Info

Publication number
MXPA02012682A
MXPA02012682A MXPA02012682A MXPA02012682A MXPA02012682A MX PA02012682 A MXPA02012682 A MX PA02012682A MX PA02012682 A MXPA02012682 A MX PA02012682A MX PA02012682 A MXPA02012682 A MX PA02012682A MX PA02012682 A MXPA02012682 A MX PA02012682A
Authority
MX
Mexico
Prior art keywords
bisphosphonates
osteoporosis
potent
months
periods
Prior art date
Application number
MXPA02012682A
Other languages
English (en)
Inventor
Zebulun D Horowitz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26952565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA02012682(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MXPA02012682A publication Critical patent/MXPA02012682A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Los bisfosfonatos, en particular los N- bisfosfonatos mas potentes, tales como acido zolendronico y sus derivados, se pueden utilizar con resultados satisfactorios para la inhibicion prolongada de la resorcion osea en condiciones de cambio oseo anormalmente incrementado, por ejemplo osteoporosis, mediante la administracion intermitente, en donde los periodos entre las administraciones de bisfosfonato son mas largos de lo que anteriormente se consideraba apropiado, por ejemplo un intervalo de dosificacion de cuando menos aproximadamente meses, o con menos frecuencia.
MXPA02012682A 2000-06-20 2001-06-18 Metodo para administrar bisfosfonatos. MXPA02012682A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59713500A 2000-06-20 2000-06-20
US26768901P 2001-02-09 2001-02-09
PCT/EP2001/006850 WO2001097788A2 (en) 2000-06-20 2001-06-18 Method of administering bisphosphonates

Publications (1)

Publication Number Publication Date
MXPA02012682A true MXPA02012682A (es) 2003-04-25

Family

ID=26952565

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012682A MXPA02012682A (es) 2000-06-20 2001-06-18 Metodo para administrar bisfosfonatos.

Country Status (24)

Country Link
US (1) US8052987B2 (es)
EP (1) EP1296689B3 (es)
JP (2) JP4722375B2 (es)
KR (1) KR100864743B1 (es)
CN (1) CN1272013C (es)
AT (1) ATE304856T1 (es)
AU (2) AU7410901A (es)
BR (1) BR0111806A (es)
CA (1) CA2410201C (es)
CY (2) CY1113740T1 (es)
CZ (1) CZ301972B6 (es)
DE (1) DE60113537T3 (es)
DK (1) DK1296689T3 (es)
ES (2) ES2394211T3 (es)
HU (1) HU228400B1 (es)
IL (2) IL153229A0 (es)
MX (1) MXPA02012682A (es)
NO (1) NO330459B1 (es)
NZ (1) NZ523086A (es)
PL (1) PL203087B1 (es)
PT (1) PT1591122E (es)
SK (1) SK287278B6 (es)
TW (1) TWI289451B (es)
WO (1) WO2001097788A2 (es)

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US9949992B2 (en) 2011-11-16 2018-04-24 Duke University Bisphosphonate compositions and methods for treating and\or reducing cardiac dysfunction
CN103623465B (zh) * 2013-11-21 2015-12-30 彭江 一种可局部调节成破骨活性的组织工程骨支架及制备方法
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KR20180115979A (ko) * 2017-04-14 2018-10-24 연세대학교 산학협력단 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물
GB201716716D0 (en) 2017-10-12 2017-11-29 Univ Of Hertfordshire Higher Education Corporation Method for coating particles
KR20210124958A (ko) * 2018-11-02 2021-10-15 앰퍼샌드 바이오파마슈티컬스, 인코포레이티드 국소적으로 적용되는 완충제(buffers)를 사용하는 양이온 과부하 및 전해질 불균형의 위험 가능성 관리를 위한 제형 및 방법
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Also Published As

Publication number Publication date
IL153229A (en) 2007-07-24
HU228400B1 (en) 2013-03-28
WO2001097788A2 (en) 2001-12-27
NO20026117L (no) 2002-12-19
JP2003535889A (ja) 2003-12-02
JP2005247873A (ja) 2005-09-15
DK1296689T3 (da) 2005-11-28
CN1620300A (zh) 2005-05-25
CY1113740T1 (el) 2015-08-05
PT1591122E (pt) 2012-12-12
CA2410201C (en) 2010-10-26
HUP0301164A2 (hu) 2003-08-28
SK18082002A3 (sk) 2003-08-05
AU7410901A (en) 2002-01-02
NZ523086A (en) 2007-07-27
WO2001097788A3 (en) 2002-06-27
EP1296689B3 (en) 2013-02-13
EP1296689A2 (en) 2003-04-02
ES2247123T7 (es) 2013-03-01
ATE304856T1 (de) 2005-10-15
PL358224A1 (en) 2004-08-09
CZ301972B6 (cs) 2010-08-18
NO330459B1 (no) 2011-04-18
SK287278B6 (sk) 2010-05-07
CY2013011I2 (el) 2015-08-05
PL203087B1 (pl) 2009-08-31
HUP0301164A3 (en) 2005-11-28
KR20030015283A (ko) 2003-02-20
CY2013011I1 (el) 2015-08-05
CA2410201A1 (en) 2001-12-27
KR100864743B1 (ko) 2008-10-22
NO20026117D0 (no) 2002-12-19
IL153229A0 (en) 2003-07-06
US20030181421A1 (en) 2003-09-25
CZ20024134A3 (cs) 2003-06-18
ES2394211T3 (es) 2013-01-23
HK1072539A1 (en) 2005-09-02
EP1296689B1 (en) 2005-09-21
DE60113537T2 (de) 2006-06-29
ES2247123T3 (es) 2006-03-01
DE60113537T3 (de) 2013-05-29
AU2001274109B2 (en) 2004-12-23
JP5005188B2 (ja) 2012-08-22
CN1272013C (zh) 2006-08-30
US8052987B2 (en) 2011-11-08
DE60113537D1 (de) 2006-02-02
TWI289451B (en) 2007-11-11
JP4722375B2 (ja) 2011-07-13
BR0111806A (pt) 2003-05-20

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