[go: up one dir, main page]

MXPA01007169A - 1-(6-metilpiridin-3-il)-2-(4-(metilsulfonil)fenil)etanona y metodo para su elaboracion. - Google Patents

1-(6-metilpiridin-3-il)-2-(4-(metilsulfonil)fenil)etanona y metodo para su elaboracion.

Info

Publication number
MXPA01007169A
MXPA01007169A MXPA01007169A MXPA01007169A MXPA01007169A MX PA01007169 A MXPA01007169 A MX PA01007169A MX PA01007169 A MXPA01007169 A MX PA01007169A MX PA01007169 A MXPA01007169 A MX PA01007169A MX PA01007169 A MXPA01007169 A MX PA01007169A
Authority
MX
Mexico
Prior art keywords
methylpyridine
ethanone
methylsulfonyl
phenyl
preparation
Prior art date
Application number
MXPA01007169A
Other languages
English (en)
Inventor
David Kuo
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Priority claimed from PCT/EP2000/000240 external-priority patent/WO2000042014A2/de
Publication of MXPA01007169A publication Critical patent/MXPA01007169A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe un nuevo producto de partida para la elaboracion de inhibidores de COX-2, el compuesto 1- (6- metilpiridin-3-il) -2-[ (4- (metilsulfonil) fenil]etanona de la formula (ver formula) asi como a un metodo para su elaboracion.
MXPA01007169A 1999-01-14 2000-01-13 1-(6-metilpiridin-3-il)-2-(4-(metilsulfonil)fenil)etanona y metodo para su elaboracion. MXPA01007169A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99100590 1999-01-14
US14599699P 1999-07-29 1999-07-29
PCT/EP2000/000240 WO2000042014A2 (de) 1999-01-14 2000-01-13 1-(6-methylpyridin-3-yl)-2-((4-(methylsulfonyl)phenyl)ethanon und verfahren zu seiner herstellung

Publications (1)

Publication Number Publication Date
MXPA01007169A true MXPA01007169A (es) 2003-06-06

Family

ID=26152856

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01007169A MXPA01007169A (es) 1999-01-14 2000-01-13 1-(6-metilpiridin-3-il)-2-(4-(metilsulfonil)fenil)etanona y metodo para su elaboracion.

Country Status (5)

Country Link
US (2) US7141673B1 (es)
KR (1) KR100446324B1 (es)
IL (2) IL143981A (es)
MX (1) MXPA01007169A (es)
NO (1) NO319822B1 (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313683A (en) 1963-04-22 1967-04-11 Lilly Co Eli Nematocidal and fungicidal methods
FR2074674A1 (en) 1970-01-16 1971-10-08 Simafex Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water
US4155909A (en) 1977-06-13 1979-05-22 Philip Morris Incorporated 2-Alkyl nicotinoids and processes for their production
US5596008A (en) 1995-02-10 1997-01-21 G. D. Searle & Co. 3,4-Diaryl substituted pyridines for the treatment of inflammation
BRPI9710372B8 (pt) 1996-07-18 2021-05-25 Merck Canada Inc composto, e, composição farmacêutica.
TW492959B (en) 1997-04-18 2002-07-01 Merck & Co Inc Process for making 2-aryl-3-aryl-5-halo pyridines useful as cox-2 inhibitors
AR015938A1 (es) 1997-09-25 2001-05-30 Merck Sharp & Dohme Procedimiento para preparar diaril piridinas utiles como inhibidores cox-2 y compuesto intermediario
HU227627B1 (en) 1998-04-24 2011-10-28 Merck Sharp & Dohme Process for synthesizing pyridine derivatives as cox-2 inhibitors and the intermediates
US6515134B1 (en) * 1999-02-16 2003-02-04 Kaneka Corporation Substituted acetylpridine derivatives and process for the preparation of intermediates for optically active beta-3 agonist by the use of the same
US6566527B1 (en) * 1999-07-27 2003-05-20 Merck & Co., Inc. Process for preparing 1-(6-methylpyridin-3-yl)-2-[4-methylsulphonyl)-phenyl]ethanone

Also Published As

Publication number Publication date
US7141673B1 (en) 2006-11-28
NO20013498D0 (no) 2001-07-13
US7355048B2 (en) 2008-04-08
IL176734A0 (en) 2009-02-11
IL176734A (en) 2010-12-30
KR20010089587A (ko) 2001-10-06
KR100446324B1 (ko) 2004-08-30
NO319822B1 (no) 2005-09-19
NO20013498L (no) 2001-09-05
US20050159458A1 (en) 2005-07-21
IL143981A (en) 2006-12-31

Similar Documents

Publication Publication Date Title
YU5503A (sh) Nesteroidni supresori zapaljenja
AP2000001889A0 (en) Substituted ozoazaheterocyclyl factor Xa inhibitors.
IS6614A (is) Ný tríasólpýrimídínefnasambönd
PL371127A1 (en) 6-aminomorphinane derivatives, method for the production and use thereof
EP1466898A4 (en) INHIBITORS OF THE PRODUCTION / SEPARATION OF BETA-AMYLOIDS PROTEINS
NO984344L (no) Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger
SE0103710D0 (sv) Compounds
WO2001081316A3 (en) Substituted phenyl farnesyltransferase inhibitors
MY157375A (en) Novel crystalline forms of <2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1h-[1,2,3]triazol-4-yl]-pyridin-3-yl>-(2-chlorophenyl)-methanone
AP2002002466A0 (en) 3-heterocycliylpropanohydroxamic acid PCP INHIBITORS.
ATE359283T1 (de) Substituierte pyrazinonverbindungen zur behandlung von entzündungen
NO20016151L (no) Fremstilling av substituerte piperidin-4-oner
WO2002014313A3 (de) Neue beta-amyloid inhibitoren, verfahren zu deren herstellung und deren verwendung als arzneimittel
WO2004030664A3 (en) New compounds for the inhibition of undesired cell proliferation and use thereof
BG104575A (en) Matrix metalloprotease inhibitors
DK1102765T3 (da) Fremgangsmåde til syntese af (1H)-benzo[c]quinolizin-3-on-derivater
PT1265891E (pt) Novos derivados heterociclicos ou benzenicos do acido lipoico sua preparacao e sua aplicacao a titulo de medicamentos
MXPA03002493A (es) Proceso eficiente para preparacion de un inhibidor del factor xa.
MXPA01007169A (es) 1-(6-metilpiridin-3-il)-2-(4-(metilsulfonil)fenil)etanona y metodo para su elaboracion.
WO2000042014A3 (de) 1-(6-methylpyridin-3-yl)-2-((4-(methylsulfonyl)phenyl)ethanon und verfahren zu seiner herstellung
AU2002339158A1 (en) 2-(3-sulfonylamino-2-oxopyrrolidin-1-yl)propanamides as factor xa inhibitors
AU6721000A (en) Synthesis of 3-ethoxy-4-ethoxycarbonyl phenyl acetic acid, key acid synthon ofrepaglinide
WO2004096828A3 (fr) Nouveau procede et intermediaires de preparation de composes 19-nor-steroïdes
WO2001083423A3 (en) 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof
PL359727A1 (en) Crystalline pharmaceutical

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees