MXPA99003876A - Compositions for reducing odor on skin - Google Patents

Abstract

The present invention relates to an aqueous odor-absorbing composition which is safe for use on human skin comprising from about 0.1%to about 5%, by weight of the composition, of solubilized, water-soluble, uncomplexed cyclodextrin;from about 0.5%to about 30%, by weight of the composition, of a linear dimethicone having a nominal viscosity of 350 centistokes or less;and an aqueous carrier. The compositions can also comprise one or more of the following optional components:low molecular weight polyols;water-soluble antimicrobial preservatives;zinc salts;water-soluble polymers;soluble carbonate and/or bicarbonate salts;chelating agents;zeolites;activated carbon;and mixtures thereof. The present invention also relates the use of the aforementioned compositions in reducing body, vaginal, and or environmental odors on skin. The composition can be applied directly as a spray, poured from a bottle and applied by hand, or applied via a wipe.

Description

COMPOSITIONS TO REDUCE THE ODOR IN THE SKIN BACKGROUND OF THE INVENTION Body odor is most commonly caused by fatty acids in skin and by the bad odors of microbial sources. Human skin is naturally populated by numerous microorganisms that are fed by various secreted substances on the skin (eccrine and apocrine sweat, and bait), cell debris on the skin, skin breaking products and the same organisms. Said unpleasant body odors are mainly organic molecules having different structures and functional groups, such as amines, acids, alcohols, aldehydes, ketones, phenolics, polycyclics, indoles, aromatics, polyaromatics, etc. They can also be made from functional groups containing sulfur, such as thiol, mercáptan, sulfur and / or disulfide groups. In addition, daily contact with substances that leave non-pleasurable and / or prolonged odors in the body and hair of the individual is almost unavoidable. Foods such as fish, onions, garlic and other spices, cooking odors, smoke, tobacco and gasoline are just some of the common environmental sources of bad smells in everyday life. Numerous attempts have been made to hide unpleasant odors with the use of deodorant compositions. Such compositions are typically based on the presence of heavy fragrances or perfumes to cover odors. Not only are such perfumes and fragrances unsuitable to completely cover odors, they are often Irritants for the user. The very smell of the perfume or fragrance can be irritating or damaging to the user's skin, respiratory system and / or sense of smell, as well as to the individuals who are close to it. Attempts have been made to inhibit the microbes responsible for the body odor of the moisture / moist environment that are needed to proliferate and grow. Such efforts include the use of powders and / or antiperspirants. Body dusts are often undesirable as they can be difficult to apply and can be spread or adhered to clothing. Antiperspirants are not always preferred in the body odor control product since, when used throughout the body, they can interfere with the body's thermal regulating process by inhibiting perspiration through the action of astringent salts. Additionally, such salts can be irritating to a large number of users, particularly when applied to sensitive areas such as the pelvic region. Other deodorant compositions intended to combat / control body odor associated with skin secretions, which have been described in the chemical and cosmetic literature, include emulsion sticks or suspensoid sticks, aerosols, movable ball deodorants, pads, dewdrops rubber, and even bars of soap. Such known deodorants try to control the odor through a variety of means. For example, the patent of E.U.A. No. 5,525,331 to Betts, issued on June 11 of 1996, describes compositions that inhibit the growth of microorganisms in bodily secretions. Deodorants can also include antibacterial compounds that help destroy / control the amount of bacteria present in the skin, thus minimizing the odor produced by the bacterial metabolism of skin secretions. Zeolites such as those marketed under the trade name ABSCENTS by the Union Carbide Corporation and UOP are known odor absorbers. However, such commonly known solid odor absorbers, in addition to the known activated charcoal odor absorbers, lose their functionality when wet. Therefore, when wetted by body fluids or when carried in an aqueous solution, such odor absorbers are not preferred, since they lose their desired odor absorbing characteristics. further, zeolites can cause a "rough" sensation if they are deposited excessively on the skin. The patent of E.U.A. No. 5,534,165, to Pilosof et al., Issued July 9, 1996, discloses aqueous odor-absorbing compositions for controlling odors in fabrics, particularly garments. Said compositions, however, are not used directly on human skin. Thus, there is still a need for an improved odor absorbing composition, which is essentially free of irritating ingredients such as perfumes or astringent anti-transplants and which is Safe and effective for use throughout the body. Most particularly, there is a need for a convenient, smeared composition that is capable of absorbing a broad spectrum of body and environmental odors that are not completely suppressed by the aforementioned means. It has been found that such controlled body odor control can be safely delivered to the entire body by application of a composition, which is smeared on the skin, and which incorporates odor absorption, cyclodextrins that do not form complexes in a aqueous solution. It has been discovered that a particular advantage of the present invention is the ability to provide convenient, non-irritating odor protection when applied to the hidden areas of the skin such as the pelvic region, the outer vagina, the line of the pantyhose, the line of the bra, and the folds of the skin, which can be very sensitive. In addition, the use of cyclodextrin that does not form complexes and other optional components in the control of body and environmental odor in human skin has been discovered. Said compositions and uses thereof provide a solution that smears on the skin with optimum characteristics of odor absorption and extended shelf life. In addition, it has been discovered that the aforementioned benefits can be delivered in an aqueous solution which also optionally provides auxiliary skin benefits to the user such as protection and / or wetting. These and other objects of the present invention will become apparent from the following detailed description.

All percentages, relationships and parts in the present, in the specification, examples and claims are by weight, unless stated otherwise. The term "g", as used herein refers to gram. The term "ml", as used herein refers to millimeter.

BRIEF DESCRIPTION OF THE INVENTION The present invention relates to an aqueous odor absorption composition that is safe for use on human skin, containing from about 0.1% to about 5% by weight of the solubilized, water-soluble cyclodextrin composition, which does not form complexes; from about 0.5% to about 30% by weight of the composition, of a linear dimethicone having a nominal viscosity of 350 centitokes less; and a watery vehicle. The compositions may also comprise one or more of the following optional components: low molecular weight polyols; antimicrobial preservatives soluble in water; zinc salts; water soluble polymers, soluble carbonate and / or bicarbonate salts; chelating agents; zeolites; activated carbon and mixtures thereof. The compositions can be applied directly as a sprinkler, pour from a bottle and applied by hand, or applied with a cloth.

The present invention also relates to the use of cyclodextrin compositions in the control of body, vaginal and / or environmental odors in the skin.

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a perfume-free, aqueous, odor-absorbing composition. The present invention also relates to the use of the odor absorbing composition to reduce body and / or environmental odor in the skin. The composition can be applied directly to the skin as a sprinkler, pour from a bottle and applied by hand, or applied using a cloth that is damp. The term "body fluids", as used herein, includes eccrine sweat, aprocrine sweat, bait, reasonable moisture accumulation of transpidermal water loss, vaginal discharge, urine and mixtures thereof. The term "body odor", as used herein, refers to odors that are generated as a result of the natural functioning of a human body. Such odors include, but are not limited to, odors produced by microorganisms of human skin (i.e., bacterial decomposition of skin secretions), urine, or vaginal discharge, and mixtures thereof.

The term "total body" refers to the total external surface of human or mammalian skin. The term "vaginal odor" refers specifically to those body odors that emanate from the pelvic region of a woman, particularly the vagina and the line of the panties. A detailed description of the essential and optional components of the present invention is given below. CICLQDEXTRINA As used herein, the term "cyclodextrin" includes any known cyclodextrin such as unsubstituted cyclodextrins containing from 6 to 12 glucose units, especially, alpha-cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin and / or its derivatives and / or mixtures thereof. The term "non-compliant cyclodextrin", as used herein, refers to the cavities within the cyclodextrin in the solution of the present invention must remain essentially unfilled while in the solution, to allow the Cyclodextrin absorbs several odor molecules when the solution is applied to a surface. The term "water-soluble cyclodextrin, which does not form complexes", as used herein, refers to cyclodextrin that does not form complexes having a minimum solubility limit of 1% (one gram in 100 grams of water).

The non-derived beta-cyclodextrin may be present at a level up to its solubility limit of about 1.85% at room temperature. When beta-ciciodextrin is applied to a rinsing substrate, levels above its solubility limit can be used. Preferably, the cyclodextrins used in the present invention are highly water soluble, such as: alpha-cyclodextrin and / or derivatives thereof, gamma-cyclodextrin and / or derivatives thereof, beta-cyclodextrin derivative, and / or mixtures from the same. The cyclodextrin derivatives consist mainly of molecules where some of the OH groups are converted to OR groups. The highly water soluble cyclodextrins are those which have solubility in water of at least about 10 g in 100 ml of water at room temperature, preferably at least about 20 g in 100 ml of water, most preferably at least about 25 g in water. 100 ml of water at room temperature. Most preferred are beta-cyclodextrin, hydroxypropyl alpha-cyclodextrin, hydroxypropyl beta-cyclodextrin, alpha-cyclodextrin-methylated or beta-cyclodextrin-methylated. It is also preferred to use a mixture of cyclodextrins. These mixtures absorb body odors more broadly by subjecting complexes with a broader scale of odoriferous molecules that have a larger scale of molecular sizes. The cyclodextrin levels are from about 0.1% to about 5%, preferably from about 0.2% to about 4%, most preferably from about 0.3% to about 3%, most preferably from about 0.4% to about 2% by weight of the composition.

The concentrated compositions can also be used.

When a concentrated product is used, that is, when the level of cyclodextrin used is from about 3% to about 5%, it is preferred to dilute the composition before applying to the skin to avoid the sticky feel of the skin and / or an amount undesirable residue. Preferably, the cyclodextrin is diluted from about 50% to about 2000, most preferably from about 60% to about 1000, most preferably from about 75% to about 500% by weight of the water composition. The formation of complexes between ciclodextppa and odor molecules occurs rapidly in the presence of water when solubilized ciciodextrins are first applied to the skin. Additionally, cyclodextrins that are dried on the surface of the skin will once again achieve enhanced absorption capacities when re-wetting with body fluids. The above is convenient for the user because the cyclodextrins, when found on dry skin, they will not fill their cavities with other environmental odors that could make them otherwise less efficient to absorb body odors. Most particularly, in the solubilization of cyclodextrins by bodily noises, the isolated cavities become available to form the inclusion complexes with the body odor molecules. In this way, finally, the availability of cyclodextrin Solubilized that does not form complexes is essential for an effective and efficient amount of odor control development. A more complete description of the cyclodextrins and derivatives of the cyclodextrin useful in the present invention can be found in the patent of E.U.A. No. 5,534,165, Pilosol et al., Issued July 9, 1996, which is incorporated herein by reference in its entirety. DIMETICONE. The compositions of the present invention also comprise an effective level of dimethicone, which helps to prevent or reduce skin irritation and may also contribute other benefits such as reduction of skin friction. An "effective level" of dimethicone, as used herein, is a level that effectively provides the desired benefits of dimethicone to the skin. The dimethicones used in the present invention should be linear dimethicones having nominal viscosities of 350 centistokes or less. Preferred are linear dimethicones having nominal viscosities of about 50 centistokes to about 100 centistokes, available from Dow corning® 200 Fluid. Typically, dimethicone is present at a level of from about 0.5% to about 30%, preferably from about 1% to about 2% by weight of the composition. AQUEOUS VEHICLE. The cyclodextrins useful in the present invention must be solubilized and dispersed in an aqueous vehicle. The diluted aqueous solution provides the maximum separation of cyclodextrin molecules in the skin and maximizes the possibility that an odor molecule interacts with a molecule of cyclodextrin. A watery vehicle is also beneficial because it provides cleaning means, convenient to apply the cyclodextrin to the desired sites of the skin. Additionally, an aqueous vehicle can impart a degree of cleaning potential by washing the cell debris from the skin and secretions from the skin to which the bacteria are delivered, as well as the bacteria themselves. The term "aqueous vehicle", as used herein, refers to water and / or any water-soluble material suitable for use as a solvent. Any water can be used, such as distilled, deionized or tap water. The water not only serves as a liquid vehicle for the cyclodextripaps, but also facilitates the complex formation reaction between the cyclodextrin molecules and any odor molecule that is found at the site of the skin when applied to the composition. The aqueous vehicle of the present invention will typically comprise from about 80% to about 98% of the composition of the present invention. Preferably, the composition of the present invention comprises the aqueous vehicle from about 85% to about 95%. LOW MOLECULAR WEIGHT POLYOLES. The present composition may also comprise low molecular weight polyols. The phrase "low molecular weight polyols", as used herein, is refers to linear organic compounds, of a functional group of alcohol per molecule where the molecular weight is less than 95. Low molecular weight polyols with relatively high boiling points, when compared to water, such as propylene glycol and glycerol , are preferred ingredients for improving the development of odor control of the composition of the present invention. Without being limited by the foregoing, it is believed that the incorporation of a small amount of low molecular weight glycols in the composition of the present invention drives the formation of cyclodextrin inclusion complexes as the skin dries. It is believed that the ability of polyols to remain in the skin for a period longer than water, as the skin dries, allows to form complex compounds with the cyclodextrin and some malodorous molecules. It is believed that the addition of the snails will fill the empty space in the cyclodextrin cavity which is unable to be filled by some malodor molecules of relatively lower sizes. Preferably, the glycol used is propylene glycol. Cyclodextrins prepared by processes resulting in a level of said polyols are highly desirable, since they can be used without the removal of the polyols. Optimally, the low molecular weight polyols will be added at an effective level to aid in the formation of complexes without significantly reducing the available cyclodextrin capacity to absorb malodor molecules having larger sizes. Typically, low molecular weight polyols are added to the composition of the present invention at a level of from about 0.01% to about 1% by weight of the composition, preferably from about 0.02% to about 0.5%, most preferably from about 0.03% to about 0.3% by weight of the composition. ANTIMICROBIAL CONSERVATIVE. The compositions may optionally, but preferably, contain solubilized, mild, water-soluble antimicrobial preservatives that are effective to inhibit and / or regulate microbial growth in the composition. Contamination of the compositions of the present invention by microorganisms and subsequent microbial growth can result in unpleasant or malodorous compositions. Similarly, the microorganisms are typically found in cyclodextrin supplies and their growth in aqueous solutions is possible. The inclusion of antimicrobial preservatives helps increase the storage stability of the composition of the present invention. In the present invention, the water soluble antimicrobial preservative includes in an effective amount. The phrase "effective amount" of water-soluble antimicrobial preservative as used herein refers to a level sufficient to prevent filtration, or prevent the growth of micro-organisms unexpectedly added to the composition, during the specific period. Antimicrobial preservatives useful in the present invention include biocidal and biostatic compounds (substances which kill microorganisms and / or regulate the growth of microorganisms).

Suitable antimicrobial preservatives have a solubility of 0. 3% or more. In addition, suitable preservatives are those that can be brought into contact with the skin without high potential irritation. Preferred antimicrobial preservatives are those that are soluble in water and effective at low levels because water-insoluble organic preservatives can form inclusion complexes with the cyclodextrin molecules and compete with the malodor molecules for the cyclodextrin cavities, thus making the cyclodextrins effective as odor control assets. Suitable preservatives for use in the present compositions are described in full in The Theory and Practice of Industrial Pharmacv. by Lachman, Lieberman, Kanig, 3rd. Edition, pages 466-467 and 520-522 (1986), and Patent of E.U.A. No. 5,534,165, to Pilosof et al., Issued July 9, 1996, which are incorporated herein by reference. It is preferred to use a broad spectrum conservative such as that which is effective in bacteria (gram positive and gram negative) and fungi. A limited spectrum conservative such as one that is effective only in a single group of microorganisms, for example fungi, can be used in combination with a broad spectrum conservator or other limited spectrum conservatives with complementary and / or supplementary activity. A mixture of broad spectrum preservatives can also be used.

Preferred water-soluble water preservatives include the following: sodium hydroxymethylglycinate (ie Suttocide® A. from Sutton) Labs, Chatham, NJ); sodium benzoate; cyclic organic nitrogen compounds including imidazolidenedione compounds (such as dimethyoldimethyl-diettoin, ie Lonly Glydant® Plus, diazolidinyl urea and imidazolidinyl urea) and bicyclic oxazolidine polymethoxy; phenyl and phenoxy compounds including benzylalcohol, 2-phenoxyethanol and hexamidiniseethionate; quaternary ammonium compounds including poly (meth) methylene biguanide; low molecular weight aldehydes including formaldehyde and glutaraldehyde; halogenated compounds including chlorhexidine, chlorobutanol and dibromopropamide. and mixtures thereof.

To reserve most cyclodextrins for pain control, the minimum amount of effective preservative should be used. Preferred levels of preservative are from about 0.0001% to about 2%, most preferably from about 0.0002% to about 1%, most preferably from about 0.01% to about 0.5% by weight of the composition. pH. The aqueous compositions of the present invention should have a pH of from about 3 to about 10, preferably from about 3.5 to about 8, most preferably from about 3.5 to about 6. Some conventional pH regulating agents are known in the prior art, which can be used to adjust the pH to the desired level if necessary. For example, combinations of salts and acids, such as the following examples: sodium lactate, sodium citrate, potassium phosphate, lactic acid, citric acid, phosphoric acid, are also useful. A part of the effectiveness of said ingredients can be lost as they form complexes with the cyclodextrin, so that care is taken in the formulation to adjust the above. Other optional pH regulators appear in The Theorv and Prediction of Industrial Pharmacv. Lachman, Lieberman and Kanig, Third Edition, incorporated herein by reference. OTHER COMPONENTS. The composition of the present invention may optionally contain odor control adjuncts, such as zinc salts, water-soluble cationic polymers, water-soluble anionic polymers, water-soluble carbonate salts, water-soluble bicarbonate salts, zeolites. , and activated carbon; chelating agents; dyes and / or antiperspirants. Optionally, but highly preferred, the present invention may include zinc salts for the absorption of added odor and / or antimicrobial benefit for the cyclodextrin solution. Zinc compounds have been used more frequently because of their ability to reduce malodor, ie, in mouthwash products, as described in the U.S. Patents. Nos. 4,325,939, issued April 20, 1982 and 4,469,674, issued September 4, 1983, to N. B. Shah, and others, which are incorporated herein by reference in their totals. Zinc salts highly ionized and soluble in water, such as chloride of zinc, provide the best source of zinc ions. The zinc salt, zinc phenolsulfonate, is preferred for use in the skin composition of the present invention; although others may be within the scope of the present invention. However, care must be taken in selecting the zinc salts as well as their levels, since some may be irritating to the skin and therefore are not preferred for use in the present invention. Said zinc salts aid in the absorption of low molecular weight amine and sulfur containing compounds. Low molecular weight amines and low molecular weight sulfur containing materials such as sulfur and mercáptans are components of various types of odors such as food odors (garlic, onion), mouth odor, urine odors, and particularly body odor / perspiration. When the zinc salts are added to the composition of the present invention, they are typically present at a level of from about 0.1% to about 10%, preferably from about 0.2% to about 8%, most preferably from about 0.3% to about 5%. % by weight of the composition.

Some water-soluble polymers such as the water-soluble cationic polymer and water-soluble anionic polymers can be used in the composition of the present invention to provide additional odor control benefits. Water-soluble cationic polymers such as those containing amino functionalities, amido functionalities, and mixtures thereof, are useful in the present invention for controlling certain odors of acid type. Water-soluble anionic polymers such as polyacrylic acids and their water-soluble salts are useful in the present invention to control certain amino-type odors. Preferred polyacrylic acids and their alkali metal salts have an average molecular weight of less than about 20,000, most preferably less than about 5,000. Also suitable are polymers containing sulfonic acid groups, phosphoric acid groups, phosphonic acid groups, and their water soluble salts, and mixtures thereof, and mixtures with carboxylic acid and carboxylate groups. Water-soluble polymers containing cationic and anionic functionalities are also suitable. Examples of said polymers are given in the patent of E.U.A. 4, 909,986, issued March 20, 1990, to N. Kobayashi and A. Kawazoe, incorporated herein by reference in its entirety. Another example of water-soluble polymers containing cationic and anionic functionalities is a copolymer of dimethyldiallylammonium chloride and acrylic acid, commercially available under the tradename Merquat 280® from Calgon. Although the aforementioned water-soluble polymers are useful in the present invention, when such materials are used, care must be taken to ensure that no residual acrylic acid is present due to safety issues associated with the presence of the acrylic acid.

Preferred salts are sodium carbonate monohydrate, potassium carbonate, sodium bicarbonate, sodium bicarbonate, potassium bicarbonate and mixtures thereof. When such salts are added to the composition of the present invention, they are typically present at a level of from about 0.1% to about 5%, preferably from about 0.2% to about 3%, most preferably from about 0.3% to about 2% in weight of the composition.

When said salts are added to the composition of the present invention, it is preferred that the incompatible metal salts are not present in the invention. Preferably, when such salts are used, the composition should be essentially free of zinc and other incompatible metal ions, ie, Ca. Fe, etc., which form water-insoluble salts. Amine acid chelating agents, such as ethylenediaminetretraacetic acid (EDTA), can optionally be added to the composition of the present invention to boost the activity of the water-soluble, antimicrobial preservative. When the chelating agent is added to the composition of the present invention, it is typically present at a level of from about 0.01% to about 0.3%, preferably from about 0.05% to about 0.2% by weight of the composition. It is important that the composition of the present invention is essentially free of any metal ion that can be chelated by any chelating agent that is added to the composition of the present invention, because the metal ions form a complex, and are deactivated, with the chelating agents. It is also used in the zeolites in the present invention. A preferred class of zeolite is characterized as "intermediate" silicate / aluminate zeolites, particularly for use in amine-type absorption odors. "High" zeolites are preferred for controlling sulfur-containing odors, ie, thiols, mercaptans. The zeolites, the "intermediate" and "high", are explained in more detail in the U.S. Patent. 5,429,628 to Trinh et al., Issued July 4, 1995, which is incorporated herein by reference in its entirety. The carbon material suitable for use in the present invention is the material well known in commercial practice as an absorbent for organic molecules and / or for air purification purposes. Often, said carbon material is called "activated" carbon or "activated" charcoal. Said carbon is available from commercial sources under the trade names Calgon-Type CPG®; Type PCB®; Type SGL®; Type CAL®; and Type OL®. The dyes and dyes may optionally be added to the odor absorption compositions for visual appearance and developmental impression. When dyes are used, care must be taken in the selection of dyes that do not stain the skin. Preferred colorants for use in the present compositions are dyes highly soluble in water, ie, acid blue, acid blue 104, acid green 1, green acid, yellow 3 acid, sodium salt of yellow acid 73, D &C green no. 5, 6 and 8, D &C yellow no. 7, 8, 10 and 11, D &C violet no. 2, D &C blue no. 1 and 2, FD &C, green no. 3, FD &C yellow no. 5 and 6 and mixtures thereof. Optionally, the present skin composition may also comprise known antiperspirants and / or known deodorant compositions that are not explicitly described above.

Examples of suitable antiperspirants for the aqueous solutions include aluminum-zirconium tetrachlorhydrexglycine, aluminum-zirconium pentachlorohydrate, aluminum sesquichlorhydrate or aluminum chlorohydrate and mixtures thereof.

PROCEDURE FOR PREPARING COMPOSITIONS The compositions used in the present invention are prepared by a process comprising the steps of preparing an aqueous carrier mixture and all the ingredients (except dimethicone) upon mixing until all are dissolved and the mixture is homogeneous. The term "homogeneous", as used herein, refers to the uniformly distributed solution. If dimethicone is used, the composition preparation process further comprises: mixing the mixture with the dimethicone using a high cut (for example using a mill) until the composition is homogeneous.

Although the compositions of the present invention are to be applied directly to the skin, several applicators are useful for delivering the compositions throughout the body for maximum odor control. For example, the compositions are preferably deposited on a paper product such as a cloth which is subsequently contacted with the skin to transfer the composition to the skin. Any cloth structure and / or cloth structure preparation methods commonly known in the art can be used in the present invention. The cloth comprises flexible distribution means. The term "flexible dispensing means", as used herein, includes papers, garments, nonwovens, films, foams, sponges, rolls, pads, cloths, pieces of cotton and the like. Preferred cloth substrates comprise a porous material, such as nonwoven substrates, foams or sponges, which are capable of maintaining the composition within the pores of the substrates. Examples of particularly useful and inexpensive cellulosic nonwovens in the present invention are described in the patent of E.U.A. No. 4,191, 609, Trokhan, issued March 4, 1980. Another description of useful cloths and method of making such cloths is found in world patent 95/17175, to Mitra et al., Publication date, June 29 of 1995. Both references are incorporated herein as a reference in their totalities. Techniques for combining cloth substrates with the composition of the present invention are well known in the art.

Examples of common methods of combining the composition to the cloth substrate may include coating, dipping, soaking or sprinkling, the cloth substrate with the composition of the present invention. When dimethicone is included in the present invention, care must be taken to ensure that the solution is mixed with high cut (such as milling) to obtain a homogeneous solution immediately prior to application to the cloths. The composition of the present invention is added to the cloth substrate at a level sufficient to provide the desired odor control and / or other desired skin benefits of the present invention. A convenient method of combining the composition of the present invention with the selected substrate is to place the substrate in an open package that will finally house the finished product until use. The composition is poured into the substrate and allows its distribution. Where the composition comprises dimethicone, it is preferred that the homogeneous composition is poured into each cloth individually rather than in a set of cloths. The packaging is then closed and the cloths are ready for use. The composition of the present invention can also be provided as a liquid by a spray distributor or bottle. A manually activated spray dispenser is preferred to avoid the use of aerosols that may be irritating to sensitive areas of the body. The spray dispensers useful in the present invention are described in more detail in the patent of E.U.A. No. 5,534,165, which is incorporated herein by reference in its entirety.

USE OF THE COMPOSITIONS IN THE SMELL OF REDUCTION The present invention also comprises the use of compositions described herein in the reduction of body odor comprising the application of the compositions described herein on the skin. The present invention also comprises the use of compositions described herein to reduce vaginal odor comprising the application of compositions described herein in a pelvic region, external vagina, and / or panty line. However, the compositions of the present invention should not be inserted into the vagina, nor applied to the vulva. The present invention also comprises the use of the compositions described herein to reduce environmental odors on the skin comprising the application of the compositions described herein on the skin. An "effective amount" of the compositions of the present invention, as used herein, refers to an amount sufficient to absorb body, vaginal, and / or environmental odor to the extent that it is not discernible by the human sense of the smell. The compositions of the present invention are topically applied directly to the skin or hair. The compositions can be delivered by placing the composition in distribution means and applying an effective amount by spraying or rubbing the composition on the desired surface of the skin; typically throughout the body. Preferably, the dispensing means is a cloth comprising flexible dispensing means, when the composition does not comprise dimethicone, a spray distributor. The distribution of the composition of the present invention can be achieved by the use of a preformed cloth, a hand, or a spray bottle. Alternatively, when the composition does not include dimethicone, the user may combine the composition of the present invention with a cloth comprising flexible distribution means of his own choice. To do so, the user simply selects flexible dispensing means such as a laundry, and pours, from a bottle or other suitable container, a solution of the composition of the present invention into the selected flexible dispensing means that apply the composition to the desired area of the body. In this way, the user can use as much as he wishes the composition of the present invention, depending on the intended use and the necessary degree of odor control. The following are non-limiting examples that illustrate the formulations and methods of use of the present invention EXAMPLE I, II AND III Example I Example II Eiemolo III Inherentientes P% P & P% EDTA of tetrasodium 0.1 0.1 ~ Zinc Chloride 1 - - Zinc Phenolsulfate - - 1 Suttocide® A - 0.5 0.25 Glydant Plus® 0.2 - - Benzalkonium Chloride 0.14 - - Sodium Bensoate - - 0.1 Beta-cyclodextrin 5 1 3 hydroxypropyl Dimethicone (100 3 1 -centistokes) Distilled water the rest the rest the rest * Optionally, the propylene glycol can be added to the previous examples from about 1% to about 1%. Citric acid can also be added to the above examples at approximately 0.12%. Prepare examples I and II as follows: add tetrasodium EDTA to approximately 66% of the distilled water in each formula and mix until dissolved. Then add each of the ingredients residuals, except for dimethicone, in the order listed above, with mixing. Ensure that each ingredient dissolves or the solution is homogeneous before adding the next ingredient. Add the residual water of each of the total formulas and stir until it is homogeneous. Finally, add the dimethicone using the high cut until the dimethicone is evenly dispersed in the mixture. Prepare example III as follows: add each of the ingredients in the order listed above, with mixture, ensure that each ingredient is dissolved or the solution is homogeneous before adding the next ingredient. Finally, add the residual water of each of the formulas and shake until it is homogeneous. Preparation for application to the skin: the solutions of the present invention, such as those formed from the examples, can be loaded onto a cloth, poured into a spray device, or poured directly into the skin or a flexible dispersion medium of the selection of the user for the convenient application to the skin. To prepare cloths: place the dry cloth or cloth substance inside an open package that will finally contain the finished product. Where the composition comprises dimethicone, the mixture must be mixed once more vigorously to obtain a uniformly dispersed mixture. Pour the composition on the fabric to distribute it. Close the packaging for storage until the consumer uses it.

Prepare aspersion: Pour the composition into the selected spray pack. Close the package to store until the consumer uses it. Example IV. A woman with tension urinary continence finds that the moisture associated with this condition causes vaginal odor. After urinating, the woman cleans her outer vagina with a cloth containing the composition in Example I. Cyclodextrin and zinc salts in the complex of the composition with odors such as the polycyclic compounds and amines (respectively) found in the urine . The woman observes less odor after using the cloths. Example V. A woman with large breasts notes that when she exercises she tends to experience sweating and skin irritation under the breasts. Before and after exercising, apply the composition of Example II with the cloth. Spread the composition under the breasts and the composition provides protection against odor and against odor compounds that are expelled with sweat and / or decompositions of sweat. Said woman observes odor and feels more comfortable after using the cloth. Example V I. A man has several allergies to cosmetic deodorants and antiperspirants and avoids using such products, which results in an uncontrolled and embarrassing body odor. Your doctor suggests that you apply the mild odor absorption composition of Example III. The man applies the composition by spraying every morning after bathing, and does not suffer allergic reaction; he also does not suffer from embarrassing body odor. The man keeps a bag of cloths in the job, which also contains the composition of example III, for convenient and discreet reapplication as required. Example Vil. A man is cooking fish and a sauce that requires garlic, onions and several peppers. He sees that his hands and hair smell the food and he wants to remove those odors from his body. The man rubs his hands and hair with cloths containing the composition in Example I. The shoulder observes less odor after using the cloths. Example VIII. A woman finds that after she smokes a cigar during her break at work, her hands and face smell of smoke and tobacco. Apply the composition of Example II using a preformed cloth. Open a package and rub the cloth (which is wet with the composition) on your face and hands. The composition removes the odors of residual smoke and tobacco that seem unpleasant to you. The woman observes less odor and feels more comfortable when returning to her desk after using the spray. Example IX. A man, when going to an important meeting, stops to put gasoline in his car. When filling the gas tank, it splashes on your hands. The man rubs his hands with a paper towel, but the smell of gasoline remains in his hands. The man removes a small bottle from his bag, which contains the composition of Example III. Open the bottle and pour some of the composition into your hands. Then he smells his hands and notes that the smell of gas is no longer present.

Claims (16)

NOVELTY OF THE INVENTION CLAIMS

1. - An aqueous odor absorption composition containing: a) from about 0.1% to about 5% by weight of the composition, of solubilized cyclodextrin that is not complexed, soluble in water, b) of about 0.5 about 30% by weight of the composition, and a linear dimethicone having a nominal viscosity of 350 centistokes or less; and c) an aqueous vehicle.

2. An aqueous odor absorption composition, containing: a) from about 0.1% to about 5% by weight of the cyclodextrin composition that is not subjected to solubilized complex, soluble in water, b) from about 0.5% to about 30% of the composition, of a linear dimethicone having a nominal viscosity of 350 centistokes or less; c) an effective amount of solubilized preservative, soluble in water, antimicrobin; and d) an aqueous vehicle.

3. The composition according to claim 2, further characterized in that the water-soluble antimicrobial preservative is sodium hydroxymethylglycinate.

4. The composition according to any of claim 1-3, further characterized in that it comprises about 0.01% to about 1% by weight of the low molecular weight polyol composition.

5. The composition according to claim 1, 2, 3, further characterized in that the cyclodextrin is selected from the group consisting of beta-cyclodextrins, derivatives of beta-cilcodextrins, alpha-cyclodextrins, derivatives of alpha-cyclodextrins, gamma -cyclodextrins, derived from gamma-cyclodextrins, and mixtures thereof.

6. The composition according to claim 1, 2 or 3, further characterized in that it comprises one or more adjunct odor control materials selected from the group consisting of zinc salts, zeolites, activated carbon, soluble water ep polymers, water soluble carbonate, water soluble bicarbonates, and mixtures thereof. .

7. The composition according to claim 4, further characterized in that the low molecular weight polyols are selected from the group consisting of propylene glycol, glycerol and mixtures thereof.

8. A preformed cloth composition, further characterized in that the composition according to claim 1, 2 or 3 is deposited on a cloth comprising flexible distribution means.

9. The use of an odor absorption composition for the manufacture of a topical deodorant to be applied to human skin to reduce body, vaginal and / or environmental odors.

10. - The use of an odor absorption composition for the manufacture of a topical deodorant to be applied on human skin to reduce body, vaginal and / or environmental odors, containing: a. from about 0.1% to about 5% by weight of the cyclodextrin composition which is not subjected to a solubilized complex, soluble in water; b. an effective amount of solubilized water-soluble, antimicrobial preservative; and c. a watery vehicle

11. The use according to claim 9 or 10, further characterized in that the composition further comprises from about 0.5% to about 30% by weight of the composition of a linear dimethicone having a nominal viscosity of 350 centistokes or less.

12. The use according to claim 9 or 10, further characterized in that the composition further comprises about 0.1% about 1% of the composition of low molecular weight polyols.

13. The use according to claim 9 or 10, further characterized in that the composition further comprises one or more adjunctive odor control materials selected from the group consisting of zinc salts, zeolites, activated carbon, water soluble polymers, water-soluble carbonate, water-soluble bicarbonate and mixtures thereof.

14. - The use according to claim 9 or 10, further characterized in that the skin is a pelvic region, an outer vagina and / or a line of the panty.

15. The use according to claim 9 or 10, further characterized in that the composition is applied to the skin using a cloth comprising flexible dispensing means.

16. The use according to claim 9 or 10, further characterized in that the composition is applied to the skin using a spray bottle.