MX9709571A - Device for transdermal electrotransport delivery of fentanyl and sufentanil. - Google Patents
Device for transdermal electrotransport delivery of fentanyl and sufentanil.Info
- Publication number
- MX9709571A MX9709571A MX9709571A MX9709571A MX9709571A MX 9709571 A MX9709571 A MX 9709571A MX 9709571 A MX9709571 A MX 9709571A MX 9709571 A MX9709571 A MX 9709571A MX 9709571 A MX9709571 A MX 9709571A
- Authority
- MX
- Mexico
- Prior art keywords
- fentanyl
- sufentanil
- concentration
- transdermal electrotransport
- electrotransport
- Prior art date
Links
- 229960002428 fentanyl Drugs 0.000 title abstract 6
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 title abstract 6
- 229960004739 sufentanil Drugs 0.000 title abstract 6
- GGCSSNBKKAUURC-UHFFFAOYSA-N sufentanil Chemical compound C1CN(CCC=2SC=CC=2)CCC1(COC)N(C(=O)CC)C1=CC=CC=C1 GGCSSNBKKAUURC-UHFFFAOYSA-N 0.000 title abstract 6
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 229960004379 fentanyl hydrochloride Drugs 0.000 abstract 1
- 230000004907 flux Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- LHCBOXPPRUIAQT-UHFFFAOYSA-N n-phenyl-n-[1-(2-phenylethyl)piperidin-4-yl]propanamide;hydrochloride Chemical compound Cl.C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 LHCBOXPPRUIAQT-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides an improved electrotransport drug delivery system for analgesic drugs, namely fentanyl and sufentanil. The fentanyl/sufentanil is provided as a water soluble salt (e.g., fentanyl hydrochloride) dispersed in a hydrogel formulation for use in an electrotransport device (10). In accordance with the invention, the concentration of fentanyl/sufentanil in the donor reservoir (26) solution is maintained above a predetermined minimum concentration, whereby the transdermal electrotransport flux of fentanyl/sufentanil is maintained independent of the concentration of fentanyl/sufentanil in solution.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60925695A | 1995-06-05 | 1995-06-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9709571A true MX9709571A (en) | 1998-03-31 |
Family
ID=39427892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9709571A MX9709571A (en) | 1995-06-05 | 1997-12-04 | Device for transdermal electrotransport delivery of fentanyl and sufentanil. |
Country Status (1)
| Country | Link |
|---|---|
| MX (1) | MX9709571A (en) |
-
1997
- 1997-12-04 MX MX9709571A patent/MX9709571A/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |