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MX9708013A - Procedimiento para preparar 1-(piridil)-2-ciclohexil-amina racemica y enantiomera. - Google Patents

Procedimiento para preparar 1-(piridil)-2-ciclohexil-amina racemica y enantiomera.

Info

Publication number
MX9708013A
MX9708013A MX9708013A MX9708013A MX9708013A MX 9708013 A MX9708013 A MX 9708013A MX 9708013 A MX9708013 A MX 9708013A MX 9708013 A MX9708013 A MX 9708013A MX 9708013 A MX9708013 A MX 9708013A
Authority
MX
Mexico
Prior art keywords
cyclohexylethylamine
pyridyl
enantiomeric
racemic
preparing racemic
Prior art date
Application number
MX9708013A
Other languages
English (en)
Inventor
Karl Georg Grozinger
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MX9708013A publication Critical patent/MX9708013A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Esta invencion se refiere a la preparacion de 1-(piridil)-2-ciclohexilentilamina racémica y enantiomera y, en particular, a la separacion de (+)-(S)- o (-)-(R)-1-(2-piridil)-2-ciclohexiletilamina a partir de una mezcla racémica de 1-(R,S)-(2-piridil)-2-ciclohexiletilamina. de acuerdo con esta invencion, la separacion de una mezcla racémica de 1-(piridil)-2-ciclohexiletilamina se lleva a cabo utilizando ácido 3- bromocanfo-8-sulfonico (BCSA). Esta invencion se refiere también a un procedimiento para preparar una mezcla racémica de 1-(piridil)-2-ciclohexiletilamina y BCSA libre a partir de materiales de partida fácilmente disponibles.
MX9708013A 1995-04-20 1996-11-08 Procedimiento para preparar 1-(piridil)-2-ciclohexil-amina racemica y enantiomera. MX9708013A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/425,526 US5616717A (en) 1995-04-20 1995-04-20 Process for the preparation of pure enantiomers of 1-(2-pyridyl)-2-cyclohexylethylamine
PCT/US1996/003296 WO1996033173A2 (en) 1995-04-20 1996-03-18 Process for preparing racemic and enantiomeric 1-(pyridyl)-2-cyclohexylethylamine

Publications (1)

Publication Number Publication Date
MX9708013A true MX9708013A (es) 1997-12-31

Family

ID=23686941

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9708013A MX9708013A (es) 1995-04-20 1996-11-08 Procedimiento para preparar 1-(piridil)-2-ciclohexil-amina racemica y enantiomera.

Country Status (20)

Country Link
US (1) US5616717A (es)
EP (1) EP0821672A2 (es)
JP (1) JPH11503756A (es)
KR (1) KR19990007877A (es)
CN (1) CN1183771A (es)
AU (1) AU5306896A (es)
BG (1) BG101969A (es)
BR (1) BR9608237A (es)
CA (1) CA2218480A1 (es)
CO (2) CO4480023A1 (es)
CZ (1) CZ330697A3 (es)
EE (1) EE9700268A (es)
HU (1) HUP9801583A3 (es)
MX (1) MX9708013A (es)
NO (1) NO974826L (es)
PL (1) PL322908A1 (es)
SK (1) SK139397A3 (es)
TR (1) TR199701206T1 (es)
WO (1) WO1996033173A2 (es)
ZA (1) ZA963132B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7790757B2 (en) * 1998-06-16 2010-09-07 Targacept, Inc. Compounds capable of activating cholinergic receptors
US20050131034A1 (en) * 1998-06-16 2005-06-16 Caldwell William S. Compounds capable of activating cholinergic receptors
EP1737387B1 (en) * 2004-04-02 2009-09-16 Arterial Remodelling Technologies Inc. Polymer-based stent assembly
WO2014063142A1 (en) 2012-10-19 2014-04-24 Lear Corporation Electrical terminal
US9431740B2 (en) 2013-06-21 2016-08-30 Lear Corporation Method of assembling an electrical terminal assembly
US9444205B2 (en) 2014-03-25 2016-09-13 Lear Corporation Electric connector with contact protection
US10128602B2 (en) 2014-05-13 2018-11-13 Lear Corporation Electric connector with a terminal interface
US9847591B2 (en) 2014-07-22 2017-12-19 Lear Corporation Electric terminal assembly
CN112174763B (zh) * 2020-11-27 2021-04-27 北京邦克凯姆医药科技有限公司 一种吡啶衍生物的消旋方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5296486A (en) * 1991-09-24 1994-03-22 Boehringer Ingelheim Pharmaceuticals, Inc. Leukotriene biosynthesis inhibitors

Also Published As

Publication number Publication date
CN1183771A (zh) 1998-06-03
HUP9801583A2 (hu) 1998-11-30
EP0821672A2 (en) 1998-02-04
HUP9801583A3 (en) 1998-12-28
JPH11503756A (ja) 1999-03-30
CO4480022A1 (es) 1997-07-09
AU5306896A (en) 1996-11-07
CO4480023A1 (es) 1997-07-09
BR9608237A (pt) 1999-11-30
WO1996033173A3 (en) 1996-12-05
CA2218480A1 (en) 1996-10-24
PL322908A1 (en) 1998-03-02
ZA963132B (en) 1997-11-06
BG101969A (bg) 1998-05-29
US5616717A (en) 1997-04-01
SK139397A3 (en) 1998-08-05
WO1996033173A2 (en) 1996-10-24
KR19990007877A (ko) 1999-01-25
NO974826L (no) 1997-12-17
EE9700268A (et) 1998-06-15
TR199701206T1 (xx) 1998-03-21
NO974826D0 (no) 1997-10-17
CZ330697A3 (cs) 1998-06-17

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