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MX9504349A - Derivados de aroilpiperidina. - Google Patents

Derivados de aroilpiperidina.

Info

Publication number
MX9504349A
MX9504349A MX9504349A MX9504349A MX9504349A MX 9504349 A MX9504349 A MX 9504349A MX 9504349 A MX9504349 A MX 9504349A MX 9504349 A MX9504349 A MX 9504349A MX 9504349 A MX9504349 A MX 9504349A
Authority
MX
Mexico
Prior art keywords
aroylpiperidine
derivatives
trifluoromethyl
pipindependently
naphtoylamino
Prior art date
Application number
MX9504349A
Other languages
English (en)
Inventor
Silvio Ofner
Siem Jacob Veenstra
Walter Schilling
Original Assignee
Novartis Ag Tambien Denominada
Y O Novartis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag Tambien Denominada, Y O Novartis Inc filed Critical Novartis Ag Tambien Denominada
Publication of MX9504349A publication Critical patent/MX9504349A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

La invencion se refiere a novedosas N-(3,5-bis-trifluorometil-benzoil)-2-bencil-4-(aza naftoilamino)-piperidinas de la formula I, en donde X e Y son cl anillo A está insustituido o mono- o polisustituido por sustituyentes seleccionados a partir del grupo que consiste en alquilo inferior, alcoxi inferior, halogeno, nitro, y trifluorometilo; y a las sales de los mismos, al uso de los mismos, a procesos para la preparacion de los mismos, y a composiciones farmacéuticas que comprenden un compuesto de acuerdo con la invencion o una sal farmacéuticamente aceptable de las mismas.
MX9504349A 1994-10-14 1995-10-13 Derivados de aroilpiperidina. MX9504349A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH309194 1994-10-14

Publications (1)

Publication Number Publication Date
MX9504349A true MX9504349A (es) 1997-03-29

Family

ID=4248427

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9504349A MX9504349A (es) 1994-10-14 1995-10-13 Derivados de aroilpiperidina.

Country Status (23)

Country Link
US (1) US5965562A (es)
EP (1) EP0707006B1 (es)
JP (1) JP3022951B2 (es)
KR (1) KR100413985B1 (es)
CN (1) CN1066445C (es)
AT (1) ATE178602T1 (es)
AU (1) AU705851B2 (es)
CA (1) CA2160444C (es)
DE (1) DE59505575D1 (es)
DK (1) DK0707006T3 (es)
ES (1) ES2132580T3 (es)
FI (1) FI114795B (es)
GR (1) GR3030515T3 (es)
HU (1) HUT74103A (es)
IL (1) IL115572A (es)
MX (1) MX9504349A (es)
MY (1) MY114679A (es)
NO (1) NO308034B1 (es)
NZ (1) NZ280212A (es)
RU (1) RU2158731C2 (es)
SA (1) SA96160637B1 (es)
TW (1) TW397825B (es)
ZA (1) ZA958647B (es)

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TW537894B (en) * 1998-05-26 2003-06-21 Novartis Ag A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist
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RU2309953C2 (ru) 1999-11-03 2007-11-10 Эймр Текнолоджи, Инк. Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
JP2001294582A (ja) * 2000-04-12 2001-10-23 Fuji Chemical Industries Ltd 光学活性アミノブチロラクトンの製造法
WO2002004455A2 (en) 2000-07-11 2002-01-17 Albany Molecular Research, Inc 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
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US7541357B2 (en) 2004-07-15 2009-06-02 Amr Technology, Inc. Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
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WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
KR20120034644A (ko) 2009-05-12 2012-04-12 알바니 몰레큘라 리써치, 인크. 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
DK2429296T3 (en) 2009-05-12 2018-03-12 Albany Molecular Res Inc 7 - ([1,2,4,] TRIAZOLO [1,5, -A] PYRIDIN-6-YL) -4- (3,4-DICHLORPHENYL) -1,2,3,4- TETRAHYDROISOQUINOLINE AND USE thereof
EP2429293B1 (en) 2009-05-12 2014-10-29 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
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JP2013537423A (ja) 2010-08-17 2013-10-03 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸（ｓｉＮＡ）を用いたＢ型肝炎ウイルス（ＨＢＶ）遺伝子発現のＲＮＡ干渉媒介性阻害
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Also Published As

Publication number Publication date
KR960014121A (ko) 1996-05-22
FI954829A0 (fi) 1995-10-11
TW397825B (en) 2000-07-11
NZ280212A (en) 2001-10-26
HUT74103A (en) 1996-11-28
EP0707006A1 (de) 1996-04-17
US5965562A (en) 1999-10-12
AU705851B2 (en) 1999-06-03
CA2160444A1 (en) 1996-04-15
CN1066445C (zh) 2001-05-30
RU2158731C2 (ru) 2000-11-10
NO308034B1 (no) 2000-07-10
AU3317495A (en) 1996-04-26
IL115572A (en) 2001-05-20
JP3022951B2 (ja) 2000-03-21
CN1133839A (zh) 1996-10-23
SA96160637B1 (ar) 2005-06-14
NO954067L (no) 1996-04-15
HU9502973D0 (en) 1995-12-28
IL115572A0 (en) 1996-01-19
GR3030515T3 (en) 1999-10-29
JPH08176145A (ja) 1996-07-09
DE59505575D1 (de) 1999-05-12
FI954829L (fi) 1996-04-15
KR100413985B1 (ko) 2004-03-26
CA2160444C (en) 2006-11-28
NO954067D0 (no) 1995-10-13
ZA958647B (en) 1996-04-15
ATE178602T1 (de) 1999-04-15
MY114679A (en) 2002-12-31
FI114795B (fi) 2004-12-31
DK0707006T3 (da) 1999-10-18
ES2132580T3 (es) 1999-08-16
EP0707006B1 (de) 1999-04-07

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