MX9305764A - Procedimiento para la preparacion de los esteres de la bacatina iii y dela 10-desacetil bacatina iii y productos obtenidos por medio del mismo. - Google Patents
Procedimiento para la preparacion de los esteres de la bacatina iii y dela 10-desacetil bacatina iii y productos obtenidos por medio del mismo.Info
- Publication number
- MX9305764A MX9305764A MX9305764A MX9305764A MX9305764A MX 9305764 A MX9305764 A MX 9305764A MX 9305764 A MX9305764 A MX 9305764A MX 9305764 A MX9305764 A MX 9305764A MX 9305764 A MX9305764 A MX 9305764A
- Authority
- MX
- Mexico
- Prior art keywords
- bacatin iii
- esters
- preparation
- desacetile
- dela
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
La presente invención concierne a la preparación de ésteres de la bacatinaIII y de la 10-desacetil bacatina III, de fórmula general: medianteesterificación de la bacatina III o de la 10-desacetil bacatina IIIprotegida convenientemente, de fórmula general: por medio de un ácidoactivado de fórmula general:.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9211739A FR2696464B1 (fr) | 1992-10-05 | 1992-10-05 | Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9305764A true MX9305764A (es) | 1995-01-31 |
Family
ID=9434116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9305764A MX9305764A (es) | 1992-10-05 | 1993-09-21 | Procedimiento para la preparacion de los esteres de la bacatina iii y dela 10-desacetil bacatina iii y productos obtenidos por medio del mismo. |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US5717103A (es) |
| EP (1) | EP0663905B1 (es) |
| JP (1) | JP3064419B2 (es) |
| KR (1) | KR100290663B1 (es) |
| AT (1) | ATE147734T1 (es) |
| AU (1) | AU689446B2 (es) |
| CA (1) | CA2146372C (es) |
| CZ (1) | CZ284818B6 (es) |
| DE (1) | DE69307526T2 (es) |
| DK (1) | DK0663905T3 (es) |
| ES (1) | ES2096328T3 (es) |
| FI (1) | FI115909B (es) |
| FR (1) | FR2696464B1 (es) |
| GR (1) | GR3022286T3 (es) |
| HU (1) | HU225973B1 (es) |
| MX (1) | MX9305764A (es) |
| NO (1) | NO313141B1 (es) |
| NZ (1) | NZ256443A (es) |
| PL (1) | PL178090B1 (es) |
| RU (1) | RU2123493C1 (es) |
| SK (1) | SK281035B6 (es) |
| TW (1) | TW372234B (es) |
| WO (1) | WO1994007876A1 (es) |
| ZA (1) | ZA937316B (es) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
| FR2697522B1 (fr) * | 1992-10-30 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| FR2698361B1 (fr) * | 1992-11-20 | 1995-01-13 | Rhone Poulenc Rorer Sa | Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5. |
| MX9307777A (es) | 1992-12-15 | 1994-07-29 | Upjohn Co | 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. |
| SI0703909T1 (en) * | 1993-06-11 | 2000-08-31 | Pharmacia & Upjohn Company | Delta 6,7 -taxols antineoplastic use and pharmaceutical compositions containing them |
| KR20090090403A (ko) | 1993-07-19 | 2009-08-25 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 항맥관형성 조성물, 당해 조성물로 피복된 스텐트 및 당해 스텐트의 제조방법 |
| CA2172809A1 (en) * | 1993-11-12 | 1995-05-18 | Richard A. Nugent | Pyrimidine-thioalkyl and alkylether compounds |
| IL127597A (en) * | 1994-01-28 | 2003-07-31 | Upjohn Co | Iso-taxol analogs |
| CA2178541C (en) | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
| CN1216039A (zh) * | 1996-05-08 | 1999-05-05 | 法玛西雅厄普约翰美国公司 | 制备紫杉酚的方法 |
| US6150537A (en) * | 1997-12-12 | 2000-11-21 | Emory University | Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents |
| JP4502338B2 (ja) * | 1999-09-17 | 2010-07-14 | 株式会社横浜国際バイオ研究所 | タキソイド化合物の製造法 |
| EP2289549A3 (en) | 1999-10-01 | 2011-06-15 | Immunogen, Inc. | Immunoconjugates for treating cancer |
| CA2307393A1 (en) | 2000-05-01 | 2001-11-01 | The University Of British Columbia | Ginsenoside chemotherapy |
| MXPA03002494A (es) | 2000-09-22 | 2004-05-24 | Bristol Myers Squibb Co | Metodo para reducir toxicidad de quimio terapias combinadas. |
| US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| CA2440935A1 (en) | 2001-03-13 | 2002-09-19 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| PT1392254E (pt) * | 2001-04-20 | 2007-06-29 | Univ British Columbia | Sistemas de distribuição micelares de fármacos para fármacos hidrofóbicos. |
| US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
| ITMI20021921A1 (it) * | 2002-09-10 | 2004-03-11 | Indena Spa | Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali. |
| CA2511521C (en) | 2002-12-30 | 2012-02-07 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| WO2005016241A2 (en) | 2003-05-16 | 2005-02-24 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
| US7407973B2 (en) | 2003-10-24 | 2008-08-05 | Intermune, Inc. | Use of pirfenidone in therapeutic regimens |
| US7846940B2 (en) | 2004-03-31 | 2010-12-07 | Cordis Corporation | Solution formulations of sirolimus and its analogs for CAD treatment |
| US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
| US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| WO2006089218A2 (en) | 2005-02-17 | 2006-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for modulating angiogenesis |
| CA2646156C (en) | 2006-03-22 | 2016-05-24 | Medigene Ag | Treatment of triple receptor negative breast cancer |
| WO2008005284A2 (en) | 2006-06-30 | 2008-01-10 | Cook Incorporated | Methods of manufacturing and modifying taxane coatings for implantable medical devices |
| US8420110B2 (en) | 2008-03-31 | 2013-04-16 | Cordis Corporation | Drug coated expandable devices |
| US8409601B2 (en) | 2008-03-31 | 2013-04-02 | Cordis Corporation | Rapamycin coated expandable devices |
| US8273404B2 (en) | 2008-05-19 | 2012-09-25 | Cordis Corporation | Extraction of solvents from drug containing polymer reservoirs |
| EP2859916B1 (en) | 2008-05-22 | 2017-11-29 | Galera Labs, LLC | Combination of an antimitotic agent and a selective superoxide dismutase mimetic in antitumor therapy |
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| WO2010005850A1 (en) | 2008-07-08 | 2010-01-14 | The J. David Gladstone Institutes | Methods and compositions for modulating angiogenesis |
| US8642063B2 (en) | 2008-08-22 | 2014-02-04 | Cook Medical Technologies Llc | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent |
| PL388144A1 (pl) | 2009-05-29 | 2010-12-06 | Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością | Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie |
| US20120303115A1 (en) | 2011-05-25 | 2012-11-29 | Dadino Ronald C | Expandable devices coated with a rapamycin composition |
| US20120302954A1 (en) | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
| US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
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| KR102132246B1 (ko) | 2013-02-15 | 2020-07-09 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 키메라 항원 수용체 및 이의 이용 방법 |
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| US10654875B2 (en) | 2015-11-12 | 2020-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery |
| TWI760319B (zh) | 2015-12-30 | 2022-04-11 | 杏國新藥股份有限公司 | 乳癌治療 |
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| TWI852903B (zh) | 2017-01-05 | 2024-08-21 | 杏國新藥股份有限公司 | 胰臟癌治療 |
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| EP3630189A4 (en) | 2017-05-24 | 2021-06-23 | The Board of Regents of The University of Texas System | LINKER FOR ANTIBODY MEDICINAL CONJUGATES |
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| WO2019195596A1 (en) | 2018-04-06 | 2019-10-10 | The Regents Of The University Of California | Methods of treating glioblastomas |
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| BR112022011158A2 (pt) | 2019-12-12 | 2022-08-30 | Ignite Immunotherapy Inc | Vírus vaccinia oncolítico variante e métodos de uso do mesmo |
| MX2022009355A (es) | 2020-01-29 | 2022-09-02 | Kenjockety Biotechnology Inc | Anticuerpo anti-mdr1 y uso del mismo. |
| US20230212305A1 (en) | 2020-06-04 | 2023-07-06 | Kenjockety Biotechnology, Inc. | Anti-abcg2 antibodies and uses thereof |
| JP7768902B2 (ja) | 2020-06-04 | 2025-11-12 | ウィリアム ロバート アラスーン リビング トラスト デイテッド オーガスト 29, 2016 | Abcg2排出ポンプ-がん抗原多重特異性抗体並びにそれらに関連する組成物、試薬、キット、及び方法 |
| AU2021310520A1 (en) | 2020-07-14 | 2023-02-16 | Pfizer Inc. | Recombinant vaccinia virus |
| CA3193588A1 (en) | 2020-09-02 | 2022-03-10 | Kenjockety Biotechnology, Inc. | Anti-abcc1 antibodies and uses thereof |
| AU2021380659A1 (en) | 2020-11-13 | 2023-06-01 | Kenjockety Biotechnology, Inc. | Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof |
| AU2021382033A1 (en) | 2020-11-20 | 2023-06-22 | R.P. Scherer Technologies, Llc | Glycoside dual-cleavage linkers for antibody-drug conjugates |
| EP4448007A1 (en) | 2021-12-13 | 2024-10-23 | William Robert Arathoon Living Trust Dated August 29, 2016 | Anti-abcb1 antibodies |
| WO2023159220A1 (en) | 2022-02-18 | 2023-08-24 | Kenjockety Biotechnology, Inc. | Anti-cd47 antibodies |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US34277A (en) * | 1862-01-28 | Improvement in lamps | ||
| US4942184A (en) * | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
| USRE34277E (en) * | 1988-04-06 | 1993-06-08 | Centre National De La Recherche Scientifique | Process for preparing taxol |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| MX9102128A (es) * | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
| FR2696458B1 (fr) * | 1992-10-05 | 1994-11-10 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| FR2696460B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
-
1992
- 1992-10-05 FR FR9211739A patent/FR2696464B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-21 MX MX9305764A patent/MX9305764A/es unknown
- 1993-10-01 ZA ZA937316A patent/ZA937316B/xx unknown
- 1993-10-02 TW TW082108116A patent/TW372234B/zh not_active IP Right Cessation
- 1993-10-04 DK DK93921980.4T patent/DK0663905T3/da active
- 1993-10-04 NZ NZ256443A patent/NZ256443A/en not_active IP Right Cessation
- 1993-10-04 AT AT93921980T patent/ATE147734T1/de active
- 1993-10-04 AU AU51148/93A patent/AU689446B2/en not_active Expired
- 1993-10-04 CA CA002146372A patent/CA2146372C/fr not_active Expired - Lifetime
- 1993-10-04 JP JP6508785A patent/JP3064419B2/ja not_active Expired - Lifetime
- 1993-10-04 PL PL93308239A patent/PL178090B1/pl unknown
- 1993-10-04 US US08/411,691 patent/US5717103A/en not_active Expired - Lifetime
- 1993-10-04 WO PCT/FR1993/000965 patent/WO1994007876A1/fr not_active Ceased
- 1993-10-04 DE DE69307526T patent/DE69307526T2/de not_active Expired - Lifetime
- 1993-10-04 EP EP93921980A patent/EP0663905B1/fr not_active Expired - Lifetime
- 1993-10-04 RU RU95110766A patent/RU2123493C1/ru active
- 1993-10-04 HU HU9500970A patent/HU225973B1/hu unknown
- 1993-10-04 CZ CZ95839A patent/CZ284818B6/cs not_active IP Right Cessation
- 1993-10-04 SK SK438-95A patent/SK281035B6/sk not_active IP Right Cessation
- 1993-10-04 KR KR1019950701300A patent/KR100290663B1/ko not_active Expired - Lifetime
- 1993-10-04 ES ES93921980T patent/ES2096328T3/es not_active Expired - Lifetime
-
1995
- 1995-03-29 NO NO19951200A patent/NO313141B1/no not_active IP Right Cessation
- 1995-04-04 FI FI951593A patent/FI115909B/fi not_active IP Right Cessation
-
1997
- 1997-01-16 GR GR960402654T patent/GR3022286T3/el unknown
- 1997-10-31 US US08/962,452 patent/US5977375A/en not_active Expired - Lifetime
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