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MX9304658A - Preparaciones en forma de particulas solidas que contienen sustancia activa. - Google Patents

Preparaciones en forma de particulas solidas que contienen sustancia activa.

Info

Publication number
MX9304658A
MX9304658A MX9304658A MX9304658A MX9304658A MX 9304658 A MX9304658 A MX 9304658A MX 9304658 A MX9304658 A MX 9304658A MX 9304658 A MX9304658 A MX 9304658A MX 9304658 A MX9304658 A MX 9304658A
Authority
MX
Mexico
Prior art keywords
preparations
containing active
water
active substance
solid particles
Prior art date
Application number
MX9304658A
Other languages
English (en)
Inventor
Sven Grabowski
Axel Sanner
Joerg Rosenberg
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of MX9304658A publication Critical patent/MX9304658A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

El presente invento se refiere a preparaciones en forma de partículas sólidas que contienen sustancia activa, y que se obtienen por mezcla íntima de la sustancia activa con una fusión soluble en agua a partir de a) 10 a 90 en peso de un polímero A soluble en agua de una viscosidad Va de 1.000 hasta 120.000 cps, y b) 10 a 90 en peso de un polímero B soluble en agua de una viscosidad Vb de 1 hasta 500 cps como sustancia portadora, midiéndose las viscosidades Va y Vb a base de una solución acuosa al 2 en peos a 20°C según el método capilar de ASTM D 2363-72 (Farmacopea Europea, vol. III, pág. 37), y elaboración de la fusión bajo conformado en las partículas.
MX9304658A 1992-08-13 1993-08-02 Preparaciones en forma de particulas solidas que contienen sustancia activa. MX9304658A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4226753A DE4226753A1 (de) 1992-08-13 1992-08-13 Wirkstoffe enthaltende Zubereitungen in Form fester Teilchen

Publications (1)

Publication Number Publication Date
MX9304658A true MX9304658A (es) 1994-02-28

Family

ID=6465437

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304658A MX9304658A (es) 1992-08-13 1993-08-02 Preparaciones en forma de particulas solidas que contienen sustancia activa.

Country Status (12)

Country Link
US (1) US5641516A (es)
EP (1) EP0596203B1 (es)
JP (1) JPH06172160A (es)
AT (1) ATE186638T1 (es)
AU (1) AU661407B2 (es)
CA (1) CA2103961C (es)
DE (2) DE4226753A1 (es)
DK (1) DK0596203T3 (es)
ES (1) ES2140428T3 (es)
GR (1) GR3031871T3 (es)
MX (1) MX9304658A (es)
NO (1) NO307811B1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0661045T3 (da) 1992-09-18 2002-10-28 Yamanouchi Pharma Co Ltd Hydrogelpræparat med forsinket frigivelse
JP3598049B2 (ja) * 1992-09-18 2004-12-08 山之内製薬株式会社 ハイドロゲル徐放性製剤
WO1995031900A1 (en) * 1994-05-24 1995-11-30 Nippon Shinyaku Co., Ltd. Pesticide composition, production process, and pesticidal preparation
FR2725624B1 (fr) * 1994-10-14 1997-01-17 Jouveinal Inst Rech Procede de preparation de formes pharmaceutiques a liberation controlee
DE19504831A1 (de) * 1995-02-14 1996-09-05 Basf Ag Feste Wirkstoffzubereitungen enthaltend Hydroxypropylcellulose
US5695781A (en) * 1995-03-01 1997-12-09 Hallmark Pharmaceuticals, Inc. Sustained release formulation containing three different types of polymers
SI9500173B (sl) * 1995-05-19 2002-02-28 Lek, Trofazna farmacevtska oblika s konstantnim in kontroliranim sproščanjem amorfne učinkovine za enkrat dnevno aplikacijo
DE19531277A1 (de) 1995-08-25 1997-02-27 Basf Ag Verwendung von Lipiden als Hilfsmittel bei der Herstellung von festen Arzneiformen nach dem Schmelzextrusionsverfahren
DE19531684A1 (de) * 1995-08-29 1997-03-06 Bayer Ag Verfahren zur Herstellung von Arzneimittelzubereitungen mit kontrollierter Freisetzung
NZ330739A (en) 1996-05-20 1999-06-29 Janssen Pharmaceutica Nv Particulate solid dispersion of itraconazole and a water soluble polymer
DE19710009A1 (de) * 1997-03-12 1998-09-24 Knoll Ag Mehrphasige wirkstoffhaltige Zubereitungsformen
HN1998000115A (es) * 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
EP1026946A1 (de) * 1997-10-29 2000-08-16 Basf Aktiengesellschaft Feste zubereitung eines pflanzenschutzmittels
US6787157B1 (en) 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
DE19934610A1 (de) * 1999-07-23 2001-01-25 Bayer Ag Schnellfreisetzende Extrudate und Verfahren zu ihrer Herstellung sowie daraus erhältliche Zubereitungen
DE60028754T2 (de) * 1999-11-12 2007-05-31 Abbott Laboratories, Abbott Park Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
DE10215147A1 (de) * 2002-04-05 2003-10-16 Basf Ag Verwendung von Polymerisation, enthaltend thermoplastische Polymere als Filterhilfs- und/oder Stabilisierungsmittel
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
EP1832281A1 (en) * 2006-03-10 2007-09-12 Abbott GmbH & Co. KG Process for producing a solid dispersion of an active ingredient
US8617596B2 (en) 2006-04-12 2013-12-31 Nippon Soda Co., Ltd. Sustained-release tablet production process
ITPI20060098A1 (it) 2006-07-28 2008-01-29 Antonio Maccari Sistema di controllo della funzionalita' degli ugelli di una testina di stampa.
CA2669938C (en) * 2006-11-15 2016-01-05 Abbott Laboratories Solid pharmaceutical dosage formulations
JP6854162B2 (ja) * 2017-03-17 2021-04-07 ライオン株式会社 錠剤
TWI692499B (zh) * 2019-07-19 2020-05-01 怡定興科技股份有限公司 用於微針貼片之針底組成物及包含其之微針貼片
FR3107203B1 (fr) * 2020-02-14 2023-11-24 Ab7 Innovation Matrice solide composite pour la délivrance prolongée d’actifs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE636865A (es) * 1962-08-31
GB1388786A (en) * 1972-04-03 1975-03-26 Scherer Corp R P Integral solid gel-lattice dosage form of high-moisture content
US4259314A (en) * 1979-12-10 1981-03-31 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals
US4571333A (en) * 1983-06-14 1986-02-18 Syntex (U.S.A.) Inc. Controlled release naproxen and naproxen sodium tablets
US4832957A (en) * 1987-12-11 1989-05-23 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
US4814168A (en) * 1988-03-04 1989-03-21 Noven Pharmaceuticals, Inc. Transdermal multipolymer drug delivery system
DE3830353A1 (de) * 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
US5273760A (en) * 1991-12-24 1993-12-28 Euroceltigue, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer

Also Published As

Publication number Publication date
NO932875D0 (no) 1993-08-12
EP0596203A1 (de) 1994-05-11
EP0596203B1 (de) 1999-11-17
DE59309876D1 (de) 1999-12-23
DK0596203T3 (da) 2000-03-13
NO932875L (no) 1994-02-14
ES2140428T3 (es) 2000-03-01
US5641516A (en) 1997-06-24
CA2103961A1 (en) 1994-02-14
DE4226753A1 (de) 1994-02-17
AU4457293A (en) 1994-02-17
CA2103961C (en) 2005-08-09
AU661407B2 (en) 1995-07-20
JPH06172160A (ja) 1994-06-21
NO307811B1 (no) 2000-06-05
GR3031871T3 (en) 2000-02-29
ATE186638T1 (de) 1999-12-15

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