MX9301155A - NEW SULFONAMIDOCARBOXAMIDES AND PROCEDURE FOR THEIR PREPARATION. - Google Patents
NEW SULFONAMIDOCARBOXAMIDES AND PROCEDURE FOR THEIR PREPARATION.Info
- Publication number
- MX9301155A MX9301155A MX9301155A MX9301155A MX9301155A MX 9301155 A MX9301155 A MX 9301155A MX 9301155 A MX9301155 A MX 9301155A MX 9301155 A MX9301155 A MX 9301155A MX 9301155 A MX9301155 A MX 9301155A
- Authority
- MX
- Mexico
- Prior art keywords
- sulfonamidocarboxamides
- new
- procedure
- preparation
- amidination
- Prior art date
Links
- 108010049003 Fibrinogen Proteins 0.000 abstract 1
- 102000008946 Fibrinogen Human genes 0.000 abstract 1
- 108090000190 Thrombin Proteins 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- 229960004072 thrombin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Las nuevas sulfonamidocarboxamidas de la fórmula (I), en donde A, M, Q, X en Y tienen el significado expuesto en la descripción, así como sus hidratos o solvatos inhiben la agregación de plaquetas en la sangre inducida por trombina y coagulación de fibrinógeno en plasma. Se preparan mediante la amidinación de un grupo amino cíclico que corresponde a agrupación X o mediante formación a amida C(O)N(Q).The new sulfonamidocarboxamides of the formula (I), where A, M, Q, X in Y have the meaning set forth in the description, as well as their hydrates or solvates inhibit thrombin-induced blood platelet aggregation and fibrinogen coagulation in plasma. They are prepared by amidination of a cyclic amino group corresponding to group X or by formation of amide C (O) N (Q).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH72892 | 1992-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9301155A true MX9301155A (en) | 1993-09-01 |
Family
ID=4193803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9301155A MX9301155A (en) | 1992-03-06 | 1993-03-02 | NEW SULFONAMIDOCARBOXAMIDES AND PROCEDURE FOR THEIR PREPARATION. |
Country Status (10)
| Country | Link |
|---|---|
| KR (1) | KR100274422B1 (en) |
| BR (1) | BR9300753A (en) |
| HR (1) | HRP930266A2 (en) |
| MX (1) | MX9301155A (en) |
| PL (1) | PL173030B1 (en) |
| SG (1) | SG48063A1 (en) |
| SI (1) | SI9300104A (en) |
| SK (1) | SK14893A3 (en) |
| YU (1) | YU14493A (en) |
| ZA (1) | ZA931403B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201303B (en) * | 1990-07-05 | 1993-03-01 | Hoffmann La Roche |
-
1993
- 1993-02-22 SG SG1996006774A patent/SG48063A1/en unknown
- 1993-02-26 ZA ZA931403A patent/ZA931403B/en unknown
- 1993-03-01 SK SK148-93A patent/SK14893A3/en unknown
- 1993-03-02 MX MX9301155A patent/MX9301155A/en unknown
- 1993-03-03 YU YU14493A patent/YU14493A/en unknown
- 1993-03-04 BR BR9300753A patent/BR9300753A/en not_active Application Discontinuation
- 1993-03-05 PL PL93297960A patent/PL173030B1/en unknown
- 1993-03-05 HR HR930266A patent/HRP930266A2/en not_active Application Discontinuation
- 1993-03-05 KR KR1019930003315A patent/KR100274422B1/en not_active Expired - Fee Related
- 1993-03-05 SI SI19939300104A patent/SI9300104A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA931403B (en) | 1993-09-06 |
| SK14893A3 (en) | 1993-11-10 |
| SI9300104A (en) | 1993-09-30 |
| PL173030B1 (en) | 1998-01-30 |
| KR100274422B1 (en) | 2000-12-15 |
| BR9300753A (en) | 1993-09-08 |
| SG48063A1 (en) | 1998-04-17 |
| HRP930266A2 (en) | 1996-04-30 |
| KR930019627A (en) | 1993-10-18 |
| PL297960A1 (en) | 1993-09-20 |
| YU14493A (en) | 1997-01-08 |
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