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MX9300603A - Derivados tiaciclicos de piperidinilo. - Google Patents

Derivados tiaciclicos de piperidinilo.

Info

Publication number
MX9300603A
MX9300603A MX9300603A MX9300603A MX9300603A MX 9300603 A MX9300603 A MX 9300603A MX 9300603 A MX9300603 A MX 9300603A MX 9300603 A MX9300603 A MX 9300603A MX 9300603 A MX9300603 A MX 9300603A
Authority
MX
Mexico
Prior art keywords
piperidinyl
derivatives
thiaciclic
treatment
diseases
Prior art date
Application number
MX9300603A
Other languages
English (en)
Inventor
Albert A Carr
John M Kane
George D Maynard
Hsien C Cheng
Mark W Dudley
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of MX9300603A publication Critical patent/MX9300603A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Derivados tiacíclicos de piperidinilo útiles en el tratamiento de enfermedades alérgicas y de enfermedades que responden al antagonismo de 5HT2, composiciones farmacéuticas y método para el tratamiento mediante el uso de estos compuestos.
MX9300603A 1992-02-13 1993-02-04 Derivados tiaciclicos de piperidinilo. MX9300603A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83565892A 1992-02-13 1992-02-13

Publications (1)

Publication Number Publication Date
MX9300603A true MX9300603A (es) 1993-09-01

Family

ID=25270117

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300603A MX9300603A (es) 1992-02-13 1993-02-04 Derivados tiaciclicos de piperidinilo.

Country Status (17)

Country Link
US (8) US5371093A (es)
EP (1) EP0626968B1 (es)
JP (1) JP3357879B2 (es)
KR (1) KR100269756B1 (es)
AT (1) ATE206119T1 (es)
AU (1) AU669156B2 (es)
CA (1) CA2129995C (es)
DE (1) DE69330823T2 (es)
DK (1) DK0626968T3 (es)
ES (1) ES2163407T3 (es)
FI (1) FI943727L (es)
HU (1) HUT71097A (es)
MX (1) MX9300603A (es)
NO (1) NO305247B1 (es)
NZ (1) NZ249286A (es)
PT (1) PT626968E (es)
WO (1) WO1993016081A1 (es)

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US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
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US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
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US7302990B2 (en) * 2004-05-06 2007-12-04 General Electric Company Method of forming concavities in the surface of a metal component, and related processes and articles
NZ554374A (en) * 2004-10-07 2010-11-26 Vitae Pharmaceuticals Inc Diaminoalkane aspartic protease inhibitors
TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
ATE520690T1 (de) * 2006-09-18 2011-09-15 Vitae Pharmaceuticals Inc Piperidinderivate als renin-inhibitoren
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100317697A1 (en) * 2007-06-20 2010-12-16 Baldwin John J Renin Inhibitors
EP2170815A2 (en) * 2007-06-20 2010-04-07 Vitae Pharmaceuticals, Inc. Renin inhibitors
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Also Published As

Publication number Publication date
KR100269756B1 (ko) 2000-10-16
JP3357879B2 (ja) 2002-12-16
NO942993D0 (no) 1994-08-12
NZ249286A (en) 1996-02-27
AU3585593A (en) 1993-09-03
EP0626968B1 (en) 2001-09-26
US5650416A (en) 1997-07-22
FI943727A0 (fi) 1994-08-12
HUT71097A (en) 1995-11-28
NO942993L (no) 1994-08-12
DE69330823D1 (en) 2001-10-31
DE69330823T2 (de) 2002-05-02
CA2129995A1 (en) 1993-08-19
US5476861A (en) 1995-12-19
ES2163407T3 (es) 2002-02-01
CA2129995C (en) 2000-04-11
NO305247B1 (no) 1999-04-26
US5596003A (en) 1997-01-21
US5739150A (en) 1998-04-14
AU669156B2 (en) 1996-05-30
WO1993016081A1 (en) 1993-08-19
EP0626968A4 (es) 1995-01-04
US5541200A (en) 1996-07-30
ATE206119T1 (de) 2001-10-15
FI943727A7 (fi) 1994-08-12
KR950700309A (ko) 1995-01-16
US5602147A (en) 1997-02-11
US5631268A (en) 1997-05-20
FI943727L (fi) 1994-08-12
US5371093A (en) 1994-12-06
JPH07506346A (ja) 1995-07-13
DK0626968T3 (da) 2001-12-31
HU9402352D0 (en) 1994-10-28
PT626968E (pt) 2002-03-28
EP0626968A1 (en) 1994-12-07

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