NO960630D0 - Heterocykler anvendelige som neurokinin antagonister - Google Patents

Heterocykler anvendelige som neurokinin antagonister

Info

Publication number: NO960630D0
Authority: NO; Norway
Prior art keywords: neurokinin antagonists; heterocycles useful; heterocycles; useful; neurokinin
Prior art date: 1993-08-17

Application number

NO960630A

Other languages

English (en)

Other versions

NO960630L (no

NO305657B1 (no

Inventor

Scott Carson Miller

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-08-17

Filing date

1996-02-16

Publication date

1996-02-16

1996-02-16 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1996-02-16 Publication of NO960630L publication Critical patent/NO960630L/no

1996-02-16 Publication of NO960630D0 publication Critical patent/NO960630D0/no

1999-07-05 Publication of NO305657B1 publication Critical patent/NO305657B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO960630A 1993-08-17 1996-02-16 4-substituerte piperidinderivater og farmas°ytisk preparat derav NO305657B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939317104A GB9317104D0 (en)	1993-08-17	1993-08-17	Therapeutic heterocycles
PCT/GB1994/001777 WO1995005377A1 (en)	1993-08-17	1994-08-15	Heterocycles useful as neurokinin antagonists

Publications (3)

Publication Number	Publication Date
NO960630L NO960630L (no)	1996-02-16
NO960630D0 true NO960630D0 (no)	1996-02-16
NO305657B1 NO305657B1 (no)	1999-07-05

Family

ID=10740632

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO960630A NO305657B1 (no)	1993-08-17	1996-02-16	4-substituerte piperidinderivater og farmas°ytisk preparat derav

Country Status (24)

Country	Link
US (6)	US5567700A (no)
EP (1)	EP0714392B1 (no)
JP (1)	JP3502386B2 (no)
KR (1)	KR100359631B1 (no)
CN (1)	CN1077573C (no)
AT (1)	ATE172971T1 (no)
AU (1)	AU677091B2 (no)
CA (1)	CA2166800C (no)
CZ (1)	CZ285299B6 (no)
DE (1)	DE69414398T2 (no)
DK (1)	DK0714392T3 (no)
ES (1)	ES2123810T3 (no)
FI (1)	FI111253B (no)
GB (2)	GB9317104D0 (no)
HU (1)	HU219586B (no)
IL (1)	IL110672A (no)
MY (1)	MY112102A (no)
NO (1)	NO305657B1 (no)
NZ (1)	NZ269575A (no)
PL (1)	PL178426B1 (no)
RU (1)	RU2153498C2 (no)
SK (1)	SK281232B6 (no)
WO (1)	WO1995005377A1 (no)
ZA (1)	ZA946142B (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5583134A (en) *	1992-09-30	1996-12-10	Sanofi	1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present
GB9321557D0 (en) *	1992-11-03	1993-12-08	Zeneca Ltd	Carboxamide derivatives
GB9317104D0 (en) *	1993-08-17	1993-09-29	Zeneca Ltd	Therapeutic heterocycles
GB9322643D0 (en) *	1993-11-03	1993-12-22	Zeneca Ltd	Lactam derivatives
US5589489A (en) *	1993-12-15	1996-12-31	Zeneca Limited	Cyclic amide derivatives for treating asthma
GB9408872D0 (en) *	1994-05-03	1994-06-22	Zeneca Ltd	Heterocyclic compounds
TW432061B (en) *	1994-08-09	2001-05-01	Pfizer Res & Dev	Lactams
US5998444A (en) *	1995-10-24	1999-12-07	Zeneca Ltd.	Piperidinyl compounds as NK1 or NK2 antagonists
EP0709375B1 (en) *	1994-10-25	2005-05-18	AstraZeneca AB	Therapeutic heterocycles
GB9421709D0 (en) *	1994-10-27	1994-12-14	Zeneca Ltd	Therapeutic compounds
US6008223A (en) *	1994-10-27	1999-12-28	Zeneca Limited	Therapeutic compounds
GB9508786D0 (en)	1995-04-29	1995-06-21	Zeneca Ltd	Substituted heterocycles
US5696267A (en) *	1995-05-02	1997-12-09	Schering Corporation	Substituted oximes, hydrazones and olefins as neurokinin antagonists
US5688960A (en) *	1995-05-02	1997-11-18	Schering Corporation	Substituted oximes, hydrazones and olefins useful as neurokinin antagonists
GB9521781D0 (en) *	1995-10-24	1996-01-03	Merck Sharp & Dohme	Therapeutic agents
GB9523526D0 (en) *	1995-11-17	1996-01-17	Zeneca Ltd	Therapeutic compounds
US5998439A (en)	1996-02-21	1999-12-07	Hoescht Marion Roussel, Inc.	Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) *	1996-02-21	1999-07-13	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5932571A (en) *	1996-02-21	1999-08-03	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5789422A (en) *	1996-10-28	1998-08-04	Schering Corporation	Substituted arylalkylamines as neurokinin antagonists
ID26508A (id) *	1997-11-21	2001-01-11	Schering Corp	Oksim-oksim tersubstitusi sebagai antagonis-antagonis neurokinin
GB9924141D0 (en) *	1998-10-30	1999-12-15	Zeneca Ltd	Treatment of gastric asthma
US6063926A (en) *	1998-11-18	2000-05-16	Schering Corporation	Substituted oximes as neurokinin antagonists
US6204265B1 (en)	1998-12-23	2001-03-20	Schering Corporation	Substituted oximes and hydrazones as neurokinin antagonists
WO2000039114A2 (en) *	1998-12-23	2000-07-06	Schering Corporation	Substituted oximes and hydrazones as neurokinin antagonists
GB0015246D0 (en) *	2000-06-22	2000-08-16	Astrazeneca Ab	Method for the treatment of urinary incontinence
SE0103795D0 (sv)	2001-11-02	2001-11-02	Astrazeneca Ab	Compounds and method for the treatment of överactive bladder
SE0103668D0 (sv) *	2001-11-02	2001-11-02	Astrazeneca Ab	Method for the treatment of overactive blader
PE20030762A1 (es) *	2001-12-18	2003-09-05	Schering Corp	Compuestos heterociclicos como antagonistas nk1
US20100189797A1 (en)	2002-06-10	2010-07-29	Julien Mendlewicz	Oral antidepressant formulation
TW200508221A (en)	2003-06-13	2005-03-01	Astrazeneca Ab	New azetidine compounds
GB0326407D0 (en) *	2003-11-12	2003-12-17	Glaxo Group Ltd	Chemical compounds
TWI396686B (zh) *	2004-05-21	2013-05-21	Takeda Pharmaceutical	環狀醯胺衍生物、以及其製品和用法
GB0412865D0 (en) *	2004-06-09	2004-07-14	Glaxo Group Ltd	Chemical compounds
AR057828A1 (es)	2005-09-29	2007-12-19	Astrazeneca Ab	Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
US8106208B2 (en)	2006-05-18	2012-01-31	Albireo Ab	Benzamide compounds that act as NK receptor antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4804663A (en) *	1985-03-27	1989-02-14	Janssen Pharmaceutica N.V.	3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
IE903957A1 (en) *	1989-11-06	1991-05-08	Sanofi Sa	Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
WO1991009844A1 (en) *	1990-01-04	1991-07-11	Pfizer Inc.	Substance p antagonists
IL99320A (en) *	1990-09-05	1995-07-31	Sanofi Sa	Arylalkylamines, their preparation and pharmaceutical compositions containing them
FR2676054B1 (fr) *	1991-05-03	1993-09-03	Sanofi Elf	Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676053B1 (fr) *	1991-05-03	1993-08-27	Sanofi Elf	Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676055B1 (fr) *	1991-05-03	1993-09-03	Sanofi Elf	Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676781B1 (fr) *	1991-05-23	1995-03-31	Peugeot	Dispositif de refroidissement de l'air de suralimentation d'un moteur a combustion interne d'un vehicule.
FR2688219B1 (fr) *	1992-03-03	1994-07-08	Sanofi Elf	Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
GB9321557D0 (en) *	1992-11-03	1993-12-08	Zeneca Ltd	Carboxamide derivatives
GB9317104D0 (en) *	1993-08-17	1993-09-29	Zeneca Ltd	Therapeutic heterocycles
GB9325074D0 (en) *	1993-12-07	1994-02-02	Zeneca Ltd	Bicyclic heterocycles

1993
- 1993-08-17 GB GB939317104A patent/GB9317104D0/en active Pending
1994
- 1994-08-15 EP EP94923781A patent/EP0714392B1/en not_active Expired - Lifetime
- 1994-08-15 SK SK210-96A patent/SK281232B6/sk not_active IP Right Cessation
- 1994-08-15 DK DK94923781T patent/DK0714392T3/da active
- 1994-08-15 CZ CZ96434A patent/CZ285299B6/cs not_active IP Right Cessation
- 1994-08-15 AU AU73880/94A patent/AU677091B2/en not_active Ceased
- 1994-08-15 WO PCT/GB1994/001777 patent/WO1995005377A1/en not_active Ceased
- 1994-08-15 ZA ZA946142A patent/ZA946142B/xx unknown
- 1994-08-15 CA CA002166800A patent/CA2166800C/en not_active Expired - Fee Related
- 1994-08-15 JP JP50682295A patent/JP3502386B2/ja not_active Expired - Fee Related
- 1994-08-15 NZ NZ269575A patent/NZ269575A/en not_active IP Right Cessation
- 1994-08-15 ES ES94923781T patent/ES2123810T3/es not_active Expired - Lifetime
- 1994-08-15 HU HU9503826A patent/HU219586B/hu not_active IP Right Cessation
- 1994-08-15 DE DE69414398T patent/DE69414398T2/de not_active Expired - Fee Related
- 1994-08-15 KR KR1019960700676A patent/KR100359631B1/ko not_active Expired - Fee Related
- 1994-08-15 US US08/290,642 patent/US5567700A/en not_active Expired - Lifetime
- 1994-08-15 GB GB9416442A patent/GB9416442D0/en active Pending
- 1994-08-15 CN CN94193155A patent/CN1077573C/zh not_active Expired - Fee Related
- 1994-08-15 RU RU96105910/04A patent/RU2153498C2/ru not_active IP Right Cessation
- 1994-08-15 AT AT94923781T patent/ATE172971T1/de not_active IP Right Cessation
- 1994-08-15 PL PL94313075A patent/PL178426B1/pl not_active IP Right Cessation
- 1994-08-16 IL IL11067294A patent/IL110672A/xx not_active IP Right Cessation
- 1994-08-16 MY MYPI94002143A patent/MY112102A/en unknown
1996
- 1996-02-16 NO NO960630A patent/NO305657B1/no not_active IP Right Cessation
- 1996-02-16 FI FI960727A patent/FI111253B/fi active
- 1996-08-05 US US08/689,199 patent/US5861392A/en not_active Expired - Fee Related
1998
- 1998-06-29 US US09/106,606 patent/US5990130A/en not_active Expired - Fee Related
1999
- 1999-06-18 US US09/336,087 patent/US6124279A/en not_active Expired - Fee Related
2000
- 2000-09-22 US US09/668,257 patent/US6444809B1/en not_active Expired - Fee Related
2002
- 2002-08-30 US US10/233,160 patent/US7053213B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5567700A (en)	1996-10-22
PL313075A1 (en)	1996-05-27
KR100359631B1 (ko)	2003-01-24
CA2166800A1 (en)	1995-02-23
NO960630L (no)	1996-02-16
JPH09501439A (ja)	1997-02-10
US5861392A (en)	1999-01-19
ES2123810T3 (es)	1999-01-16
CZ43496A3 (en)	1996-05-15
US5990130A (en)	1999-11-23
WO1995005377A1 (en)	1995-02-23
DE69414398D1 (de)	1998-12-10
DK0714392T3 (da)	2001-02-05
AU7388094A (en)	1995-03-14
GB9416442D0 (en)	1994-10-05
US20030187255A1 (en)	2003-10-02
SK21096A3 (en)	1997-02-05
SK281232B6 (sk)	2001-01-18
CN1129449A (zh)	1996-08-21
NO305657B1 (no)	1999-07-05
ZA946142B (en)	1995-02-17
HU9503826D0 (en)	1996-02-28
MY112102A (en)	2001-04-30
EP0714392B1 (en)	1998-11-04
ATE172971T1 (de)	1998-11-15
CA2166800C (en)	2006-06-06
IL110672A (en)	1999-06-20
AU677091B2 (en)	1997-04-10
DE69414398T2 (de)	1999-05-06
NZ269575A (en)	1997-11-24
FI960727L (fi)	1996-02-16
GB9317104D0 (en)	1993-09-29
IL110672A0 (en)	1994-11-11
US6124279A (en)	2000-09-26
JP3502386B2 (ja)	2004-03-02
US6444809B1 (en)	2002-09-03
PL178426B1 (pl)	2000-04-28
CN1077573C (zh)	2002-01-09
HU219586B (hu)	2001-05-28
RU2153498C2 (ru)	2000-07-27
HUT75113A (en)	1997-04-28
US7053213B2 (en)	2006-05-30
EP0714392A1 (en)	1996-06-05
CZ285299B6 (cs)	1999-06-16
FI960727A0 (fi)	1996-02-16
FI111253B (fi)	2003-06-30

Publication	Publication Date	Title
FI960727A0 (fi)	1996-02-16	Neurokiniiniantagonisteina käyttökelpoiset heterosyklit
TR200102969T2 (tr)	2002-08-21	Siklik protein tirozin kinaz önleyicileri.
TR200001312T2 (tr)	2000-09-21	Benzotiyazol protein tirozin kinaz önleyicileri.
HUT74992A (en)	1997-03-28	Use of serotonin antagonist indol derivatives for producing pharmaceutical compositions using for treating fibromyalgia
SE9704545D0 (sv)	1997-12-05	Novel compounds
DK0674641T3 (da)	1999-09-27	Pyrrolopyrimidiner som CRF-antagonister
CO5011096A1 (es)	2001-02-28	Medicamentos que contienen antagonistas del receptor 5-ht3 para el tratamiento de la ibs
DK0760661T3 (da)	1999-08-30	Farmaceutiske sammensætninger omfattende en opiat-antagonist og calciumsalte, deres anvendelse til behandling af endorfin-m
TR199900318T2 (xx)	1999-05-21	IL-8 resept�r antagonistleri.
ATE230993T1 (de)	2003-02-15	Pharmazeutische zusammensetzung zur behandlung von alkoholabhängigkeit, die opioid antagonisten mit nmda-rezeptorkomplex-modulatoren enthält
MX9704037A (es)	1998-02-28	1,1-dioxidos de 1,2,5-tiadiazolidin-3-ona 2-substituida y composiciones y metodo de uso de los mismos.
MX9801890A (es)	1998-05-31	Nuevos compuestos antagonistas selectivos del receptor nk3 humano, procedimiento para su obtencion y composiciones farmaceuticas que los contienen.
ATE180781T1 (de)	1999-06-15	Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung
TR199700956T1 (xx)	1998-02-21	Indazolkarboksamidler.
AU2001290480A1 (en)	2002-04-08	Cyclized benzamide neurokinin antagonists for use in therapy
NO20014855L (no)	2001-12-06	N-(2-fenyl-4-aminobutyl)-1-naftamider som neurokinin-1- reseptorantagonister
MX9704034A (es)	1998-02-28	Derivados y composiciones de 1,1-dioxido de 2-arilcarboniloximetil-1,2,5-tiadiazolidin-3-ona substituido y metodo de uso.
DE69412073D1 (de)	1998-09-03	Xanthinderivate als adenosin-a1 rezeptor antagonisten
TR199800152T1 (xx)	1998-05-21	Endotelin Resept�r Antagonistleri
SE9302218D0 (sv)	1993-06-28	New use
DE69526738D1 (de)	2002-06-20	Endothelin-rezeptor-antagonisten
AR021502A1 (es)	2002-07-24	Uso de derivados de azabicicloalcanos n-sustituidos para el tratamiento de enfermedades del sistema central nervioso
ATE402178T1 (de)	2008-08-15	Substituierte 5,6,6a,11b-tetrahydro-7-oxa-5-aza- benzoäcüfluoren-6-carbonsäurederivate als nmda- antagonisten
TR200000916T2 (tr)	2000-07-21	İkameli piperidin türevleri.

Legal Events

Date	Code	Title	Description
2010-03-22	MM1K	Lapsed by not paying the annual fees