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MX9300586A - Nuevos fragmentos de hormona paratiroidea proceso para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Nuevos fragmentos de hormona paratiroidea proceso para su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
MX9300586A
MX9300586A MX9300586A MX9300586A MX9300586A MX 9300586 A MX9300586 A MX 9300586A MX 9300586 A MX9300586 A MX 9300586A MX 9300586 A MX9300586 A MX 9300586A MX 9300586 A MX9300586 A MX 9300586A
Authority
MX
Mexico
Prior art keywords
fragments
pct
preparation
contain
pharmaceutical compositions
Prior art date
Application number
MX9300586A
Other languages
English (en)
Inventor
Christian Duvos
Hubert Mayer
Bernd Mueller-Beckmann
Klaus Strein
Edgar Wingender
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of MX9300586A publication Critical patent/MX9300586A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención proporciona modificaciones de bPTH, pPTH y hPTH, en donde las mismas incluyen la secuencia de péptido de bPTH(3-35), pPTH(3-35 o hPTH(3-35) y también posiblemente están alargadas sobre el extremo C-terminal por un aminoácido, y posiblemente sobre el extremo N-terminal por uno o dos aminoácidos. La presente invención también proporciona un proceso para la preparación de estas modificaciones de PTH y de las composiciones farmacéuticas que las contienen.
MX9300586A 1992-02-04 1993-02-03 Nuevos fragmentos de hormona paratiroidea proceso para su preparacion y composiciones farmaceuticas que los contienen. MX9300586A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4203040A DE4203040A1 (de) 1992-02-04 1992-02-04 Neue parathormonfragmente, deren herstellung und diese enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
MX9300586A true MX9300586A (es) 1993-08-01

Family

ID=6450869

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300586A MX9300586A (es) 1992-02-04 1993-02-03 Nuevos fragmentos de hormona paratiroidea proceso para su preparacion y composiciones farmaceuticas que los contienen.

Country Status (14)

Country Link
US (1) US5783558A (es)
EP (1) EP0625163B1 (es)
JP (1) JPH07507051A (es)
KR (1) KR950700326A (es)
AT (1) ATE171952T1 (es)
AU (1) AU3628093A (es)
CA (1) CA2126974A1 (es)
DE (2) DE4203040A1 (es)
HU (1) HUT69708A (es)
IL (1) IL104580A (es)
MX (1) MX9300586A (es)
TW (1) TW286320B (es)
WO (1) WO1993015109A2 (es)
ZA (1) ZA93727B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2141588A1 (en) * 1992-08-05 1994-02-17 Sandra R. Hilliker Parathyroid hormone fragments and analogs
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
DE19538687A1 (de) * 1995-10-17 1997-04-24 Boehringer Mannheim Gmbh Stabile pharmazeutische Darreichungsformen enthaltend Parathormon
WO1999006563A1 (en) 1997-07-30 1999-02-11 Emory University Novel bone mineralization proteins, dna, vectors, expression systems
AU3673699A (en) * 1998-05-05 1999-11-23 Beth Israel Deaconess Medical Center Pth2 receptor selective compounds
US7820393B2 (en) * 1999-01-14 2010-10-26 Scantibodies Laboratory, Inc. Methods, kits and antibodies for detecting parathyroid hormone
US6689566B1 (en) 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone
US20080108086A1 (en) * 1999-06-02 2008-05-08 Cantor Thomas L Parathyroid hormone antagonists and uses thereof
WO2004028444A2 (en) * 1999-06-02 2004-04-08 Scantibodies Laboratory, Inc. Parathyroid hormone antagonists and uses thereof
WO2003059291A2 (en) 2002-01-10 2003-07-24 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs
US20040067526A1 (en) * 2002-10-03 2004-04-08 Cantor Thomas L. Methods for diagnosing and guiding treatment of bone turnover disease
KR100540659B1 (ko) * 2003-07-02 2006-01-10 삼성전자주식회사 이미지 확대 인쇄 방법과 장치 및 컴퓨터 프로그램을저장하는 컴퓨터로 읽을 수 있는 기록 매체
US7541140B2 (en) * 2004-06-03 2009-06-02 Scantibodies Laboratory, Inc. Assessing risk for kidney stones using parathyroid hormone agonist and antagonist
CA2628945A1 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
JP2013512688A (ja) 2009-12-07 2013-04-18 ミシガン テクノロジカル ユニバーシティ クロクマの副甲状腺ホルモン及びクロクマの副甲状腺ホルモンを使用する方法
CN108066740A (zh) * 2016-11-07 2018-05-25 亿菩升（上海）生物科技有限公司 牛骨肽在制备治疗和预防骨质疏松的药物和食物中的应用
CN111057139B (zh) * 2018-10-17 2023-12-22 南京华威医药科技集团有限公司 一种制备特立帕肽的新工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) * 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
US4423037A (en) * 1982-05-13 1983-12-27 The General Hospital Corporation Inhibitors of peptide hormone action
US4833125A (en) * 1986-12-05 1989-05-23 The General Hospital Corporation Method of increasing bone mass
US5457092A (en) * 1987-07-30 1995-10-10 Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) Methods of promoting bone growth in mammals comprising administration of modified parathyroid hormone
DE3725320A1 (de) * 1987-07-30 1989-02-09 Biotechnolog Forschung Gmbh Expressionsvektoren und verfahren unter deren verwendung zur gewinnung von cro/ss-galaktosidase/pth-fusionsproteinen und von pth
DE3935738A1 (de) * 1989-10-27 1991-05-08 Forssmann Wolf Georg Arzneimittel, enthaltend das humane parathormon-fragment (1-37) als aktiven wirkstoff
JP2952951B2 (ja) * 1990-04-12 1999-09-27 三菱化学株式会社 ペプチド誘導体
GB9020544D0 (en) * 1990-09-20 1990-10-31 Sandoz Ltd Improvements in or relating to organic compounds
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体
US5434246A (en) * 1992-03-19 1995-07-18 Takeda Chemical Industries, Ltd. Parathyroid hormone derivatives
CA2150371C (en) * 1992-12-11 2002-09-17 Dov Borovsky Materials and methods for control of pests

Also Published As

Publication number Publication date
DE59309044D1 (de) 1998-11-12
EP0625163B1 (de) 1998-10-07
HUT69708A (en) 1995-09-28
ZA93727B (en) 1994-08-03
TW286320B (es) 1996-09-21
CA2126974A1 (en) 1993-08-05
DE4203040A1 (de) 1993-08-05
WO1993015109A2 (de) 1993-08-05
IL104580A (en) 1997-01-10
ATE171952T1 (de) 1998-10-15
WO1993015109A3 (de) 1993-08-19
KR950700326A (ko) 1995-01-16
EP0625163A1 (de) 1994-11-23
AU3628093A (en) 1993-09-01
JPH07507051A (ja) 1995-08-03
HU9402272D0 (en) 1994-11-28
US5783558A (en) 1998-07-21
IL104580A0 (en) 1993-06-10

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